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INTRA-
ABDOMINAL
HYPERTENSION
ABDOMINAL
COMPARTMENT
SYNDROME
BRUNO MT
PEREIRA
MD, MSc, PhD, FACS,
FCCM
● Trauma Surgery &
Surgical Critical Care
● Associate Professor of Surgery
and Surgical Critical Care
University of Campinas/ BR
● PRESIDENT WSACS 2017-2018
WSACS
CONSENSUS
● A variety of previous definitions led to confusion
and difficulty in comparing one study with another
● IAH and ACS are recognized as factors that affect
considerably the morbidity / mortality of
critically ill patients
● Consensus Creation
(Intensive Care Medicine 2006; 32:1722-1732)
www.wsacs.org
THE STUDY
● 36 Questions
● Sept 2013 – Nov 2013
● 15 Participating Countries
184 Specialists
Portuguese: 64
English: 102
Spanish: 18
5
EXCLUDED
SPAIN (3)/ Finland (1)/ UK
(1)
179
IN GENERAL
IAH/ ACS
● 100% are doctors(3% residents or fellows)
● 100% work on ICU
● 43.8% have more than 15 years of experience
● 94.1% answered that are familiar with IAH//ACS
● 89.4% answered that are familiar with APP
● 57.9% affirm that manage less than 5 ACS cases a year
All Americas
● 48.2% consider 6 – 10 mmHg IAP normal value
● Only 22.4% answered correctly
● Only 39.7% recognized the correct definition for ACS
● 33% believe ACS is a pressure above 25 mmHg
94.1% AFFIRM THAT ARE AWARE
ABOUT IAH CONCEPTS
ALTHOUGH
WHAT IS
IT?
● IAH = ACS?
● What is IAH? What’s normal?
● What is ACS? Should I intervene? When?
● What are the risk factors?
● What if my patient has an open abdomen...
?
OBJECTIVES
1. Recognize IAH / ACS
2 . Manage and Treat
● IAP is the resting pressure contained
in the abdominal cavity
● Increases and decreases according
to the respiratory movements
● Elevated IAP is a common finding in ICU
● It is directly changed by:
PRESSURE?
INTRA-ABDOMINAL
● Volume of internal organs
● Presence of intra-abdominal volume
● Conditions limiting the expansion
of the abdominal wall
DEFINITION 1
● APP = MAP – IAP
● IAP that induces MOF is variant for each patient
● APP demonstrates severity of IAP as well
as abdominal adequacy of blood flow
● APP > IAP> arterial pH> BD> lactate
in predicting prognosis and MOF
● Failure in maintaining APP > 60 mmHg
within 3 days decreases prognosis
PRESSURE?
INTRA-ABDOMINAL
DEFINITION 2
● FG = Glomerular Filtration Pressure –
Proximal Tubular Pressure
● PTP = MAP - (2 x IAH)
● Changes in IAP has a major impact
on renal function and urine production,
increasing finally MAP
● GFP APP
● What is the first sign of elevated IAP?
GRADIENT
FILTRATION
DEFINITION 3
OLIGURIA!
● Normal IAP ranges from 5-7 mmHg
in critically ill patients in the ICU
● IAP will vary with the severity of disease
● IAP above 15 mmHg is associated with
dysfunction and failure of major
intra-abdominal organs leading to
patient’s death
REGULAR IAP
WHAT IS THE
DEFINITION 6
Regular Adult
0-5 mmHg
ICU Patient
5-7 mmHg
After Abdominal Surgery Patient
10-15 mmHg
Septic Shock Patient
15-25 mmHg
Acute Abdomen Patient
25-40 mmHg
● Defined as sustained or repeated pathologic
elevation of IAP > 12 mmHg
● Would IAP 20-25 mmHg safe?
IAH
DEFINITION 7
FAILURE TO INTERVENE
WHEN IAP > 25 MMHG
IS ASSOCIATED WITH
POOR PROGNOSIS
CLASSIFICATION
IAH
DEFINITION 8
Grade I
IAH 12 - 15 mmHg
Grade II
IAH 16 - 20 mmHg
Grade III
IAH 21 - 25 mmHg
Grade IV
IAH > 25 mmHg
● Defined as IAP > 20 mmHg (with or without
APP < 60 mmHg) associated with MOF
or isolated organ dysfunction
● ACS = IAH + organ dysfunction
ACS
DEFINITION 9
MOST COMMON CAUSES OF
DYSFUNCTION / ORGAN FAILURE:
● Metabolic acidosis (due to resuscitation), Oliguria
(because of volume repletion), High Airway
Pressure, Refractory Hypercapnia, Hypoxemia
refractory to oxygen support and PEEP,
Intracranial hypertension
● It is a condition associated
with trauma or abdominopelvic
disease that frequently requires
early surgical intervention or
interventional radiology
(interventional radiology)
ACS
PRIMARY
DEFINITION 10 Trauma
Ascites
Tumor
● Refers to conditions which do
not originate from the
abdominopelvic topography
ACS
SECUNDARY
DEFINITION 11
Sepsis
Burns
Massive Volume
Resuscitation
● Refers to the condition where
ACS resurge after medical /
surgical treatment of primary
or secondary ACS
ACS
RECURRENT
DEFINITION 12
● IAP measurement is essential for the
diagnosis and management of IAH / ACS
● Physical examination:
● Sensibility 40 - 61 %
● Positive Predictive Value 45 - 76 %
● The IAP should be measured with the
patient in the supine position and in
expiration with the "zeroed" transducer
at the mid-axillary line
IAP
HOW TO MEASURE
DEFINITION 4
IT IS
NOT
ACCURATE!
RISK FACTORS
IAH/ ACS
● Lethal triad
● Multi transfusion /
High volume infusion (>3.5 L /24)
● Pulmonary, renal and / or hepatic dysfunction
● Ileum
● Abdominal Surgery
Risk factors should be assessed at admission
or in the presence of organ dysfunction
● Via bladder instillation of a
maximum of 25 ml saline
● Bladder measurement of IAP
is a safe, fast and
cost-effective method
WHAT IS THE
DEFINITION 5
STANDARD METHOD
FOR MEASURING
THE IAP?
One-step
intra-abdominal
pressure monitoring
BRUNO M PEREIRA
dr.bruno@gruposurgical.com.br
www.gruposurgical.com.br
PRESIDENTE ELEITO
WSACS 2017 - 2019

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Intra-abdominal Hypertension - Abdominal Compartment Syndrome part 1

  • 2. BRUNO MT PEREIRA MD, MSc, PhD, FACS, FCCM ● Trauma Surgery & Surgical Critical Care ● Associate Professor of Surgery and Surgical Critical Care University of Campinas/ BR ● PRESIDENT WSACS 2017-2018
  • 3. WSACS CONSENSUS ● A variety of previous definitions led to confusion and difficulty in comparing one study with another ● IAH and ACS are recognized as factors that affect considerably the morbidity / mortality of critically ill patients ● Consensus Creation (Intensive Care Medicine 2006; 32:1722-1732) www.wsacs.org
  • 4. THE STUDY ● 36 Questions ● Sept 2013 – Nov 2013 ● 15 Participating Countries 184 Specialists Portuguese: 64 English: 102 Spanish: 18 5 EXCLUDED SPAIN (3)/ Finland (1)/ UK (1) 179
  • 5. IN GENERAL IAH/ ACS ● 100% are doctors(3% residents or fellows) ● 100% work on ICU ● 43.8% have more than 15 years of experience ● 94.1% answered that are familiar with IAH//ACS ● 89.4% answered that are familiar with APP ● 57.9% affirm that manage less than 5 ACS cases a year All Americas
  • 6. ● 48.2% consider 6 – 10 mmHg IAP normal value ● Only 22.4% answered correctly ● Only 39.7% recognized the correct definition for ACS ● 33% believe ACS is a pressure above 25 mmHg 94.1% AFFIRM THAT ARE AWARE ABOUT IAH CONCEPTS ALTHOUGH
  • 7. WHAT IS IT? ● IAH = ACS? ● What is IAH? What’s normal? ● What is ACS? Should I intervene? When? ● What are the risk factors? ● What if my patient has an open abdomen...
  • 8. ?
  • 9. OBJECTIVES 1. Recognize IAH / ACS 2 . Manage and Treat
  • 10. ● IAP is the resting pressure contained in the abdominal cavity ● Increases and decreases according to the respiratory movements ● Elevated IAP is a common finding in ICU ● It is directly changed by: PRESSURE? INTRA-ABDOMINAL ● Volume of internal organs ● Presence of intra-abdominal volume ● Conditions limiting the expansion of the abdominal wall DEFINITION 1
  • 11. ● APP = MAP – IAP ● IAP that induces MOF is variant for each patient ● APP demonstrates severity of IAP as well as abdominal adequacy of blood flow ● APP > IAP> arterial pH> BD> lactate in predicting prognosis and MOF ● Failure in maintaining APP > 60 mmHg within 3 days decreases prognosis PRESSURE? INTRA-ABDOMINAL DEFINITION 2
  • 12. ● FG = Glomerular Filtration Pressure – Proximal Tubular Pressure ● PTP = MAP - (2 x IAH) ● Changes in IAP has a major impact on renal function and urine production, increasing finally MAP ● GFP APP ● What is the first sign of elevated IAP? GRADIENT FILTRATION DEFINITION 3 OLIGURIA!
  • 13. ● Normal IAP ranges from 5-7 mmHg in critically ill patients in the ICU ● IAP will vary with the severity of disease ● IAP above 15 mmHg is associated with dysfunction and failure of major intra-abdominal organs leading to patient’s death REGULAR IAP WHAT IS THE DEFINITION 6 Regular Adult 0-5 mmHg ICU Patient 5-7 mmHg After Abdominal Surgery Patient 10-15 mmHg Septic Shock Patient 15-25 mmHg Acute Abdomen Patient 25-40 mmHg
  • 14. ● Defined as sustained or repeated pathologic elevation of IAP > 12 mmHg ● Would IAP 20-25 mmHg safe? IAH DEFINITION 7 FAILURE TO INTERVENE WHEN IAP > 25 MMHG IS ASSOCIATED WITH POOR PROGNOSIS
  • 15. CLASSIFICATION IAH DEFINITION 8 Grade I IAH 12 - 15 mmHg Grade II IAH 16 - 20 mmHg Grade III IAH 21 - 25 mmHg Grade IV IAH > 25 mmHg
  • 16. ● Defined as IAP > 20 mmHg (with or without APP < 60 mmHg) associated with MOF or isolated organ dysfunction ● ACS = IAH + organ dysfunction ACS DEFINITION 9 MOST COMMON CAUSES OF DYSFUNCTION / ORGAN FAILURE: ● Metabolic acidosis (due to resuscitation), Oliguria (because of volume repletion), High Airway Pressure, Refractory Hypercapnia, Hypoxemia refractory to oxygen support and PEEP, Intracranial hypertension
  • 17. ● It is a condition associated with trauma or abdominopelvic disease that frequently requires early surgical intervention or interventional radiology (interventional radiology) ACS PRIMARY DEFINITION 10 Trauma Ascites Tumor
  • 18. ● Refers to conditions which do not originate from the abdominopelvic topography ACS SECUNDARY DEFINITION 11 Sepsis Burns Massive Volume Resuscitation
  • 19. ● Refers to the condition where ACS resurge after medical / surgical treatment of primary or secondary ACS ACS RECURRENT DEFINITION 12
  • 20. ● IAP measurement is essential for the diagnosis and management of IAH / ACS ● Physical examination: ● Sensibility 40 - 61 % ● Positive Predictive Value 45 - 76 % ● The IAP should be measured with the patient in the supine position and in expiration with the "zeroed" transducer at the mid-axillary line IAP HOW TO MEASURE DEFINITION 4 IT IS NOT ACCURATE!
  • 21. RISK FACTORS IAH/ ACS ● Lethal triad ● Multi transfusion / High volume infusion (>3.5 L /24) ● Pulmonary, renal and / or hepatic dysfunction ● Ileum ● Abdominal Surgery Risk factors should be assessed at admission or in the presence of organ dysfunction
  • 22. ● Via bladder instillation of a maximum of 25 ml saline ● Bladder measurement of IAP is a safe, fast and cost-effective method WHAT IS THE DEFINITION 5 STANDARD METHOD FOR MEASURING THE IAP?
  • 24.

Editor's Notes

  1. HEADS OR TAILS