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Benha University Hospital,
Egypt
elnashar53@hotmail.com
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR
Postterm pregnancy: pregnancies that last longer
than 42 weeks.
Postdate pregnancies: pregnancies that last longer
than the estimated date of confinement, (ie, 40 wk).
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR
At 40 w only 58% had delivered.
By 41 w: 74%
By 42 w: 82%.
Postterm pregnancy(>42W):
16%. (12%)
Pregnancies >41: 26%
Postdate pregnancy >40W:42% (NICE)
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR
Both postterm and postdate pregnancy is
inaccurate dating criteria.
Ultrasound dating is inaccurate for a patient
who presents late in pregnancy
An ultrasound before 20 w reduces the need
for induction for post term pregnancy
(NICE,A)
ABOUBAKR ELNASHAR
CRL: ±3-5 days,
ultrasound at 12-20 w:±1 week,
at 20-30 weeks:±2 w
after 30 weeks: ±3 w.
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR
• In high risk pregnancy
• nonreassuring surveillance,
• oligohydramnios,
• growth restriction,
• certain maternal diseases,
The risks of remaining pregnant
outweigh the risks of delivery
ABOUBAKR ELNASHAR
Diabetes in pregnancy
fivefold increase in perinatal mortality
rate: induction of labour prior to their
estimated date for delivery.
(NICE C)
ABOUBAKR ELNASHAR
Elective induction of labor at or after 39 W in
the absence of documented lung maturity
provided that
1. 36 w after a positive hCG test
2. 20 w after fetal heart tones have been
established by a fetoscope or
3. 30 w by a Doppler examination, or
4. 39 w’ have been established by a CRL or
5. by an ultrasound performed before 20 w
consistent with dates by the LMP.
ABOUBAKR ELNASHAR
B. In the low-risk pregnancy.
•The certainty of gestational age,
•cervical examination findings,
•estimated fetal weight, and
•past obstetrical history
•Involving the patient in this discussion
ABOUBAKR ELNASHAR
Inducing labor at 41 weeks’ gestation in
an accurately dated, low-risk
pregnancy, regardless of cervical
examination findings.
1. Averts the need for antepartum fetal
surveillance and
2. does not increase the cesarean
delivery rate; in fact, it may decrease
the cesarean delivery rate.
ABOUBAKR ELNASHAR
3. Perinatal morbidity and mortality do
not increase appreciably between 40-41
weeks of gestation;
4. Several complications are associated
with postterm pregnanciesa.
ABOUBAKR ELNASHAR
a.macrosomia, shoulder dystocia, and
cephalopelvic disproportion
b.perinatal mortality increases
c.risk of stillbirth increases from
1 per 3000 ongoing pregnancies at 37
weeks to
3 per 3000 ongoing pregnancies at 42
weeks to
6 per 3000 ongoing pregnancies at 43
weeks.
ABOUBAKR ELNASHAR
5. increasing the risk for cesarean
delivery with a failed induction is far
less likely in the era of safe and
effective cervical ripening agents.
ABOUBAKR ELNASHAR
#A meta-analysis by Grant reviewed 11
trials and concluded that a policy of
routine induction had a lower rate of
perinatal morbidity and cesarean
delivery, demonstrating both fetal and
maternal benefit compared to
expectant management.
ABOUBAKR ELNASHAR
#A recent review in the Cochrane
Library concluded that routine induction
in low-risk pregnancies at or after 41
weeks’ gestation is associated with a
reduction in perinatal mortality, with no
increase in the rate of instrument
deliveries or cesarean delivery.
ABOUBAKR ELNASHAR
In summary, routine induction at 41
weeks’ gestation does not increase the
cesarean delivery rate, and may
decrease it, without negatively affecting
perinatal morbidity or mortality.
In fact, there may be both maternal and
neonatal benefits to a policy of routine
induction of labor in well-dated low-risk
pregnancies at 41 weeks’ gestation.
ABOUBAKR ELNASHAR
A policy of induction of labour prior to 41
weeks would generate an increase in
workload without reducing perinatal
mortality
(NICE).
ABOUBAKR ELNASHAR
•>42 wk : should be used
•before 41 weeks: not used, not improve
outcome
ABOUBAKR ELNASHAR
From 42 weeks women who decline
induction of labour should be offered
increased antenatal monitoring consisting of
a twice weekly CTG and ultrasound
estimation of maximum amniotic pool depth.
(NICE A)
A modified biophysical profile consisting of a
nonstress test and an amniotic fluid index
have been shown to be as sensitive as a full
biophysical profile.
ABOUBAKR ELNASHAR
1.An amniotic fluid index of more than 8
cm and
2. a reactive fetal heart rate tracing are
reassuring.
ABOUBAKR ELNASHAR
3. If the tracing remains nonreactive,
a. A contraction stress test or
b. a full biophysical profile. These may also
be used if the tracing is reactive but shows
fetal heart rate decelerations.
However, in the pregnancy that is beyond 41
weeks of gestation, the threshold for
delivery should be very low.
ABOUBAKR ELNASHAR
In summary, the use of a nonstress test and
an amniotic fluid index 2 times per week for
postterm, not postdate, pregnancies may
decrease fetal mortality.
In addition, if any indication during
antepartum surveillance leads the
practitioner to question the intrauterine
environment, delivery should be the rule.
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR
Once the decision to deliver a patient
has been made, the route of delivery
and the specifics of intrapartum
management depend on
individual circumstances,
ABOUBAKR ELNASHAR
Where?
Risk factors (e.g.suspected fetal
growth compromise, previous
caesarean section and high parity): C
The induction process should not occur
on an antenatal ward.
ABOUBAKR ELNASHAR
HOW?
80% of patients who reach 42 weeks’
gestation have an unfavorable cervical
examination finding (ie, Bishop score
<7)
(Harris, 1983).
ABOUBAKR ELNASHAR
A.chemical
1. prostaglandin E1 tablets for oral or
vaginal use,
2. prostaglandin E2 gel for intracervical
application, and
3. a vaginal insert containing 10 mg of
dinoprostone.
ABOUBAKR ELNASHAR
Oxytocin compared to prostaglandins for
induction of labour
Prostaglandins should be used in preference
to using oxytocin when induction of labour is
undertaken in either nulliparous or
multiparous women with intact membranes
regardless of their cervical favourability.A
Either prostaglandins or oxytocin may be used
when induction of labour is undertaken in
nulliparous or multiparous women who have
ruptured membranes, regardless of cervical
status,as they are equally effective. A
ABOUBAKR ELNASHAR
Comparison of different regimens of oxytocin
administration
Oxytocin should not be started for 6 hours
following administration of vaginal
prostaglandins. C
In women with intact membranes amniotomy
should be performed where feasible prior to
commencement of an infusion of oxytocin. C
ABOUBAKR ELNASHAR
B. mechanical.
1. Membrane sweeping or stripping
2. Foley balloon catheters placed in the
cervix
(Sullivan, 1996),
3. extra-amniotic saline infusions, and
4. laminaria: effective
(Guinn, 2000).
ABOUBAKR ELNASHAR
.
Membrane sweeping
Prior to formal induction of labour, women
should be offered sweeping of the
membranes. A
-is not associated with an increase in
maternal or neonatal infection.
-is associated with increased levels of
discomfort during the procedure and
bleeding.
ABOUBAKR ELNASHAR
EFM
Management of complications
ABOUBAKR ELNASHAR
Intrapartum fetal monitoring: EFM
If the fetal heart rate tracing is equivocal,
a. fetal scalp stimulation,
b. fetal scalp blood sampling, and/or
c. fetal pulse oximetry
d. If the practitioner cannot find reassurance
that the fetus is tolerating labor, cesarean
delivery is recommended.
ABOUBAKR ELNASHAR
•Management of complications
presence of meconium, macrosomia,
and
fetal intolerance to labor.
ABOUBAKR ELNASHAR
A.meconium.
{increased uteroplacental insufficiency,
which leads to hypoxia in labor and
activation of the vagal system}.
1. amnioinfusion of isotonic sodium
chloride solution and 2. suctioning of
the oropharynx and nose upon
delivery of the head
ABOUBAKR ELNASHAR
B. Fetal macrosomia can lead to maternal and
fetal birth trauma and to arrest of both first-
and second-stage labor. Recognizing the
limitations of ultrasound at term, it is still
advisable to obtain
1.an estimated fetal weight prior to induction
of the postdate pregnancy.
2. mid-pelvic instrument deliveries should not
be attempted.
3. delivery plan is being prepared for shoulder
dystocia
ABOUBAKR ELNASHAR
C. uterine hypercontractility with a suspicious
or pathological cardiotocograph (CTG),
secondary to oxytocin infusions,
1. the oxytocin infusion should be decreased or
discontinued.B
2. In the presence of abnormal FHR patterns
and uterine hypercontractility (not secondary
to oxytocin infusion) tocolysis should be
considered. A suggested regime is
subcutaneous terbutaline 0.25 milligrams.
A
ABOUBAKR ELNASHAR
D. suspected or confirmed acute fetal
compromise, delivery should be accomplished
as soon as possible, taking account of the
severity of the FHR abnormality and relevant
maternal factors. The accepted standard has
been that ideally this should be accomplished
within 30 minutes. B
ABOUBAKR ELNASHAR
ABOUBAKR ELNASHAR

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Postdate pregnancy

  • 3. Postterm pregnancy: pregnancies that last longer than 42 weeks. Postdate pregnancies: pregnancies that last longer than the estimated date of confinement, (ie, 40 wk). ABOUBAKR ELNASHAR
  • 5. At 40 w only 58% had delivered. By 41 w: 74% By 42 w: 82%. Postterm pregnancy(>42W): 16%. (12%) Pregnancies >41: 26% Postdate pregnancy >40W:42% (NICE) ABOUBAKR ELNASHAR
  • 7. Both postterm and postdate pregnancy is inaccurate dating criteria. Ultrasound dating is inaccurate for a patient who presents late in pregnancy An ultrasound before 20 w reduces the need for induction for post term pregnancy (NICE,A) ABOUBAKR ELNASHAR
  • 8. CRL: ±3-5 days, ultrasound at 12-20 w:±1 week, at 20-30 weeks:±2 w after 30 weeks: ±3 w. ABOUBAKR ELNASHAR
  • 11. • In high risk pregnancy • nonreassuring surveillance, • oligohydramnios, • growth restriction, • certain maternal diseases, The risks of remaining pregnant outweigh the risks of delivery ABOUBAKR ELNASHAR
  • 12. Diabetes in pregnancy fivefold increase in perinatal mortality rate: induction of labour prior to their estimated date for delivery. (NICE C) ABOUBAKR ELNASHAR
  • 13. Elective induction of labor at or after 39 W in the absence of documented lung maturity provided that 1. 36 w after a positive hCG test 2. 20 w after fetal heart tones have been established by a fetoscope or 3. 30 w by a Doppler examination, or 4. 39 w’ have been established by a CRL or 5. by an ultrasound performed before 20 w consistent with dates by the LMP. ABOUBAKR ELNASHAR
  • 14. B. In the low-risk pregnancy. •The certainty of gestational age, •cervical examination findings, •estimated fetal weight, and •past obstetrical history •Involving the patient in this discussion ABOUBAKR ELNASHAR
  • 15. Inducing labor at 41 weeks’ gestation in an accurately dated, low-risk pregnancy, regardless of cervical examination findings. 1. Averts the need for antepartum fetal surveillance and 2. does not increase the cesarean delivery rate; in fact, it may decrease the cesarean delivery rate. ABOUBAKR ELNASHAR
  • 16. 3. Perinatal morbidity and mortality do not increase appreciably between 40-41 weeks of gestation; 4. Several complications are associated with postterm pregnanciesa. ABOUBAKR ELNASHAR
  • 17. a.macrosomia, shoulder dystocia, and cephalopelvic disproportion b.perinatal mortality increases c.risk of stillbirth increases from 1 per 3000 ongoing pregnancies at 37 weeks to 3 per 3000 ongoing pregnancies at 42 weeks to 6 per 3000 ongoing pregnancies at 43 weeks. ABOUBAKR ELNASHAR
  • 18. 5. increasing the risk for cesarean delivery with a failed induction is far less likely in the era of safe and effective cervical ripening agents. ABOUBAKR ELNASHAR
  • 19. #A meta-analysis by Grant reviewed 11 trials and concluded that a policy of routine induction had a lower rate of perinatal morbidity and cesarean delivery, demonstrating both fetal and maternal benefit compared to expectant management. ABOUBAKR ELNASHAR
  • 20. #A recent review in the Cochrane Library concluded that routine induction in low-risk pregnancies at or after 41 weeks’ gestation is associated with a reduction in perinatal mortality, with no increase in the rate of instrument deliveries or cesarean delivery. ABOUBAKR ELNASHAR
  • 21. In summary, routine induction at 41 weeks’ gestation does not increase the cesarean delivery rate, and may decrease it, without negatively affecting perinatal morbidity or mortality. In fact, there may be both maternal and neonatal benefits to a policy of routine induction of labor in well-dated low-risk pregnancies at 41 weeks’ gestation. ABOUBAKR ELNASHAR
  • 22. A policy of induction of labour prior to 41 weeks would generate an increase in workload without reducing perinatal mortality (NICE). ABOUBAKR ELNASHAR
  • 23. •>42 wk : should be used •before 41 weeks: not used, not improve outcome ABOUBAKR ELNASHAR
  • 24. From 42 weeks women who decline induction of labour should be offered increased antenatal monitoring consisting of a twice weekly CTG and ultrasound estimation of maximum amniotic pool depth. (NICE A) A modified biophysical profile consisting of a nonstress test and an amniotic fluid index have been shown to be as sensitive as a full biophysical profile. ABOUBAKR ELNASHAR
  • 25. 1.An amniotic fluid index of more than 8 cm and 2. a reactive fetal heart rate tracing are reassuring. ABOUBAKR ELNASHAR
  • 26. 3. If the tracing remains nonreactive, a. A contraction stress test or b. a full biophysical profile. These may also be used if the tracing is reactive but shows fetal heart rate decelerations. However, in the pregnancy that is beyond 41 weeks of gestation, the threshold for delivery should be very low. ABOUBAKR ELNASHAR
  • 27. In summary, the use of a nonstress test and an amniotic fluid index 2 times per week for postterm, not postdate, pregnancies may decrease fetal mortality. In addition, if any indication during antepartum surveillance leads the practitioner to question the intrauterine environment, delivery should be the rule. ABOUBAKR ELNASHAR
  • 29. Once the decision to deliver a patient has been made, the route of delivery and the specifics of intrapartum management depend on individual circumstances, ABOUBAKR ELNASHAR
  • 30. Where? Risk factors (e.g.suspected fetal growth compromise, previous caesarean section and high parity): C The induction process should not occur on an antenatal ward. ABOUBAKR ELNASHAR
  • 31. HOW? 80% of patients who reach 42 weeks’ gestation have an unfavorable cervical examination finding (ie, Bishop score <7) (Harris, 1983). ABOUBAKR ELNASHAR
  • 32. A.chemical 1. prostaglandin E1 tablets for oral or vaginal use, 2. prostaglandin E2 gel for intracervical application, and 3. a vaginal insert containing 10 mg of dinoprostone. ABOUBAKR ELNASHAR
  • 33. Oxytocin compared to prostaglandins for induction of labour Prostaglandins should be used in preference to using oxytocin when induction of labour is undertaken in either nulliparous or multiparous women with intact membranes regardless of their cervical favourability.A Either prostaglandins or oxytocin may be used when induction of labour is undertaken in nulliparous or multiparous women who have ruptured membranes, regardless of cervical status,as they are equally effective. A ABOUBAKR ELNASHAR
  • 34. Comparison of different regimens of oxytocin administration Oxytocin should not be started for 6 hours following administration of vaginal prostaglandins. C In women with intact membranes amniotomy should be performed where feasible prior to commencement of an infusion of oxytocin. C ABOUBAKR ELNASHAR
  • 35. B. mechanical. 1. Membrane sweeping or stripping 2. Foley balloon catheters placed in the cervix (Sullivan, 1996), 3. extra-amniotic saline infusions, and 4. laminaria: effective (Guinn, 2000). ABOUBAKR ELNASHAR
  • 36. . Membrane sweeping Prior to formal induction of labour, women should be offered sweeping of the membranes. A -is not associated with an increase in maternal or neonatal infection. -is associated with increased levels of discomfort during the procedure and bleeding. ABOUBAKR ELNASHAR
  • 38. Intrapartum fetal monitoring: EFM If the fetal heart rate tracing is equivocal, a. fetal scalp stimulation, b. fetal scalp blood sampling, and/or c. fetal pulse oximetry d. If the practitioner cannot find reassurance that the fetus is tolerating labor, cesarean delivery is recommended. ABOUBAKR ELNASHAR
  • 39. •Management of complications presence of meconium, macrosomia, and fetal intolerance to labor. ABOUBAKR ELNASHAR
  • 40. A.meconium. {increased uteroplacental insufficiency, which leads to hypoxia in labor and activation of the vagal system}. 1. amnioinfusion of isotonic sodium chloride solution and 2. suctioning of the oropharynx and nose upon delivery of the head ABOUBAKR ELNASHAR
  • 41. B. Fetal macrosomia can lead to maternal and fetal birth trauma and to arrest of both first- and second-stage labor. Recognizing the limitations of ultrasound at term, it is still advisable to obtain 1.an estimated fetal weight prior to induction of the postdate pregnancy. 2. mid-pelvic instrument deliveries should not be attempted. 3. delivery plan is being prepared for shoulder dystocia ABOUBAKR ELNASHAR
  • 42. C. uterine hypercontractility with a suspicious or pathological cardiotocograph (CTG), secondary to oxytocin infusions, 1. the oxytocin infusion should be decreased or discontinued.B 2. In the presence of abnormal FHR patterns and uterine hypercontractility (not secondary to oxytocin infusion) tocolysis should be considered. A suggested regime is subcutaneous terbutaline 0.25 milligrams. A ABOUBAKR ELNASHAR
  • 43. D. suspected or confirmed acute fetal compromise, delivery should be accomplished as soon as possible, taking account of the severity of the FHR abnormality and relevant maternal factors. The accepted standard has been that ideally this should be accomplished within 30 minutes. B ABOUBAKR ELNASHAR