Acinto bacter p

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elia1354

Acineobacter infection

Health & Medicine

TAXONOMY
:
Acinetobacter calcoaceticus.
1-Anitratus 2- lwoffii‫ههههههههه‬ :
Moraxellaceae‫هههه‬ ‫هه‬ ‫ههههه‬ ‫هههه‬
Moraxellaceae‫ه‬Acinetobacter‫ه‬psychrobacter
‫هههههه‬ ‫ههه‬ ‫هههههههه‬ ‫ههههه‬
.‫هههه‬ ‫هه‬

Acinetobacter Genus
•DNA
• A. calcoaceticus
• A. baumannii
• 13TU
• A. haemolyticus
• A. junii

LABORATORY IDENTIFICATION
•nutrient agar
•tryptic soy agr
•
•Herellea agar (Difco.(

Morphological Characteristics
•stationary
•
•

Cultural, and Metabolic
Characteristics
•
•
•
•
•A. Haemolyticus‫طططط‬ ‫طط‬Blood agar

Species Identification
•DNADNA16
•
•
•
•
•

NOSOCOMIAL INFECTIONS
• Respiratory Infection
• Bacteremia
• Meningitis
• Urinary Tract Infection
• Other Miscellaneous Infections

Respiratory Infection
•3-5
•ICU
•ICU
•24

Bacteremia
•
•polymicrobial bacteremia
•
•NeonatesICU11

PATHOGENESIS OF
ACINETOBACTER INFECTIONS
•
•
•
•

Virulence of Acinetobacter spp.
•
•
•
•LPS
•

TYPING SYSTEMS
• Biotyping
• Antibiograms
• Serotyping
• Phage Typing
• Bacteriocin Typing
• Multilocus Enzyme
Electrophoretic
Typing
• Plasmid Profiles
• Analysis by
Pulsed-Field Gel
Electrophoresis
• Ribotyping
• Protein Profiles
• PCR-Based
Methods

CLINICAL ANTIBIOTIC
RESISTANCE
•
•1970
• gentamicin, minocycline
• nalidixic acid, ampicillin, carbenicillin
•

ANTIBIOTIC RESISTANCE
•
• cephalosporins (cefotaxime,ceftazidime)
imipenem, tobramycin, amikacin, and
fluoroquinolones
•imipenem

BIOCHEMICAL AND GENETIC
MECHANISMS
OF ANTIBIOTIC RESISTANCE
•
•80

b-Lactams
•TEM-1TEM-2ACE-1ACE-2
•ARI-1 ARI-1imipenem
•Imipenemazlocillin
ARI-1A. junii.‫تتت‬ ‫تتت‬ ‫تتتتت‬

THERAPY OF ACINETOBACTER
INFECTIONS
•
•
•
•

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