A research professor at the University of South Florida, Dominic D’Agostino has experience in preserving performance under extreme environments, maintaining muscle function, protecting the brain, ketone supplementation and ketone ester technologies. One issue addressed by Dominic D’Agostino is whether keto can assist in mitigating neuroinflammation in the context of environmental conditions and disease pathologies. . A chronic condition of the central nervous system (CNS), neuroinflammation starts with the release of chemicals by the immune system that activate leukocytes (white blood cells) and combat infection. This is normally an acute process that enables tissue repair and the restoration of homeostasis over a period of a few hours. In rare cases, the response overstays its utility, to the point where it’s prolonged and causes symptoms such as depression, anxiety, reduced libido, appetite suppression (or increase), body weight changes, impaired cognition, fatigue, and an increase in pain sensations.

1. How Keto May Assist in Fighting Neuroinflammation.
Dominic D'Agostino

2. Introduction
A research professor at the University of South Florida, Dominic D’Agostino has
experience in preserving performance under extreme environments, maintaining muscle
function, protecting the brain, ketone supplementation and ketone ester technologies.
One issue addressed by Dominic D’Agostino is whether keto can assist in mitigating
neuroinflammation in the context of environmental conditions and disease pathologies. .

3. A chronic condition of the central nervous system (CNS), neuroinflammation starts with
the release of chemicals by the immune system that activate leukocytes (white blood
cells) and combat infection. This is normally an acute process that enables tissue repair
and the restoration of homeostasis over a period of a few hours.

4. In rare cases, the response overstays its utility, to the point where it’s prolonged and
causes symptoms such as depression, anxiety, reduced libido, appetite suppression (or
increase), body weight changes, impaired cognition, fatigue, and an increase in pain
sensations.

5. One result of chronic systemic inflammation is permeability between barriers in the
body, such as the blood brain barrier (BBB) and the gut lining. In technical terms,
microglial activation in the CNS causes pro-inflammatory cytokine production and
degrades communication between neurons. Neurological disorders associated with
such low-grade, chronic inflammation range from migraines to Alzheimer’s disease,
epilepsy and chronic fatigue syndrome.

6. Low-carb, ketogenic diets (KD) can be part of the solution, as they encourage a
metabolic shift that involves reducing excess levels of insulin and preventing spikes in
blood glucose. This in turn enables increased fatty acid mobilization and utilization, and
boosts ketone bodies within the liver. The end result is enhanced anticonvulsant and
neuroprotective activity that may contribute to a lessening of neuroinflammation.
For more information, please visit of Blog on KetoNutrition.org.