How does Vitamin D affect Testosterone? How can my DNA cause mood swings and depression? And what can I do about it? GeneSolve's Dr Richard Lee discusses body chemistry and how it affects our energy levels, mental focus, and weight loss.

3. FEEL GREAT
LOOK GREAT

9. ARE YOU IN OPTIMAL HEALTH?

10. EXHAUSTION
WAKING UP TIRED
TROUBLE SLEEPING
LACK OF FOCUS
FORGETFULLSOMETHING
WEIGHT GAIN
I USED TO BE SMARTER

12. DESCRIPTIVE
PRESCRIPTIVE

13. SICK

14. EXHAUSTION
WAKING UP TIRED
TROUBLE SLEEPING
LACK OF FOCUS
FORGETFULLSOMETHING
WEIGHT GAIN
I USED TO BE SMARTER
YOU’RE NORMAL.
YOU’RE JUST
GETTING OLD.
LET’S DO
SOME TESTS
AND FIND OUT!

15. NORMAL

16. Vitamin B12 Testosterone
(women)
Testosterone
(men)
Vitamin D SHBG
Low <200 <20 <241 <30 <10
NORMAL
(95%)
200-1100 20-89 241-827 30-100 10-50
High >1100 >90 >827 >100 >50
+ at least 60 others…

18. OPTIMAL

19. JOURNAL OF CLINICAL ENDORCINOLOGY AND METABOLISM, NOVEMBER 20, 2013
Bu B. Yeap, Helman Alfonso, S. A. Paul Chubb, David J. Handelsman, Graeme J. Hankey, Osvaldo P. Almeida, Jonathan Golledge, Paul E. Norman and Leon Flicker

20. ALL MY DATA
EXPERT SYSTEMS
OPTIMAL
+

21. ‘ALL MY DATA’
INCLUDES DNA

22.
METHYLENETETRAHYDROFOLATE REDUCTASE

23. AVOID
SHORTCUTS

24. 1. TSH
2. FREE T3 & FREE T4

25. EXPERT
SYSTEMS

27. FIND PATTERNS

29. KEEP LEARNING

30. TODAY’S LESSON

31. TOP 5 NUMBERS TO GET FROM YOUR DOCTOR NEXT TIME YOU SEE THEM:
1. WHY DO YOU THINK THAT IS?
2. WHAT CAN WE DO ABOUT IT?
AND IF ANY OF THEM ARE IN THE BOTTOM HALF OF THE NORMAL
RANGE, ASK YOUR DOCTOR:
YOUR NUMBER
TESTOSTERONE
FREE TESTOSTERONE
VITAMIN D
FREE T3
FREE T4

32. THE FUTURE

33. • MORE ACTIONABLE GENOMICS
• GETTING BETTER MEASURMENTS WITH BETTER TECHNOLOGY
(ESPECIALLY REALLY DIFFICULT ONES!)

34. CATECHOL-O-METHYLTRANSFERASE