IMPONDERABLE CONTENT TO KNOW ABOUT THE ULCER.

1. NAME - CHANDA MALVIYA
BRANCH - B. PHARMA
INSTITUTE – BANSAL COLLEGE OF
PHARMACY

2. 1. Introduction
2. What is ulcer
3. Symptoms
4. Causes
5. Mechanism of action
6. Complication
7. Treatment
8. Side effect

4. Peptic ulcer is open perforation that develop on
the inside lining of stomach and the upper part of
small intestine.

8.  Most common cause of peptic ulcer is NSAID’S
which is responsible for decrease mucus
secretion or inhibition of secretion and
baterium known as Helicobactor Pyroli.
 The H. pyroli commonly located at mucos layer
that cover and protect tissue lining of stomach
and small intestine.

10. 1. Internal bleeding
2. Slow rate of blood loss leads to anemia or
severe blood loss which require hospitilization
and blood transfusion.
3. Infection
4. Perforation in peptic ulcer leads to severe H.
pyroli infection which is responsible for
severe abdominal cavity infection result
hospitilization.

11. We can treat ulcer via two ways :
 By life style changes
 By medication

13.  Gastric acid secretion: decrease acid
secretion
 Example: H2 antagonist – cimetidine
 Proton pump inhibitor: omeprazole ,lansoprazle
pantoprazole
 Anticholinergic: propantheline
 PG analogue: misoprostol
 Gastric acid neutrilization:
 Systemic: sod. Carbonate
 Non systemic: mag. hydeoxide

14.  Ulcer protective: Ex. Sucralfate
 Anti H. pyroli drug: amoxicillin
clarithromycin

15.  Nausea
 Vomiting