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Wireless Transmission of Spirometric Measurements to ePRO Devices Used by Subjects with Asthma Stephen A. Raymond, PhD Chief Scientific Officer and Founder PHT Corporation
Relation to Session Objective ,[object Object],[object Object],[object Object],[object Object]
Spirometric Data Quality ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rationale for Wireless System ,[object Object],[object Object],[object Object]
eDiary and Wireless PEF Option1.  Wireless (short-range ~10 feet) radio link) Option 2. Manual Transcription  PEF, FEV1 from Meter to eDiary
Field Experience in Trials ,[object Object],[object Object],[object Object],[object Object]
Field Experience in Trials ,[object Object],[object Object],[object Object],[object Object]
Example 1: results ,[object Object],[object Object]
Example 1: the “manual” choice
Example 1: Sites matter
Data Quality--Completions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusions-Example 1 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Completions: Field Experience AVERAGE Completion Compliance for 3,365 Subjects *Trials still recruiting the number of subjects enrolled are shown relative to the number of planned randomized subjects . 94% 718 673 Yes 20 of 558 23 of 33 COPD 10* 74% 1,508 1,118 No 56 of 336 62 of 83 COPD 9* 96% 5,572 5,332 Yes 33 0f 45 96 of 320 Asthma 8* 89% 35,602 31,658 Yes 67 450 COPD 7 95% 127,261 120,818 Yes 76 660 COPD 6 95% 8,892 8,460 Yes 8 100 COPD 5 97% 8,266 7,996 No 22 100 Asthma 4 97% 39,932 38,416 No 72 600 Asthma 3 95% 12,826 12,195 Yes 18 172 Asthma 2 79% 398,296 316,420 No 147 1102 Asthma 1 Completion Compliance Expected Daily Diaries Received Daily Diaries eSense PiKo Sites Subjects Indication
Conclusions-Data Quality ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Disclaimer ,[object Object],[object Object],[object Object]

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Wireless Transmission Of Spirometric… By Stephen A. Raymond, Ph D

  • 1. Wireless Transmission of Spirometric Measurements to ePRO Devices Used by Subjects with Asthma Stephen A. Raymond, PhD Chief Scientific Officer and Founder PHT Corporation
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  • 5. eDiary and Wireless PEF Option1. Wireless (short-range ~10 feet) radio link) Option 2. Manual Transcription PEF, FEV1 from Meter to eDiary
  • 6.
  • 7.
  • 8.
  • 9. Example 1: the “manual” choice
  • 11.
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  • 13. Completions: Field Experience AVERAGE Completion Compliance for 3,365 Subjects *Trials still recruiting the number of subjects enrolled are shown relative to the number of planned randomized subjects . 94% 718 673 Yes 20 of 558 23 of 33 COPD 10* 74% 1,508 1,118 No 56 of 336 62 of 83 COPD 9* 96% 5,572 5,332 Yes 33 0f 45 96 of 320 Asthma 8* 89% 35,602 31,658 Yes 67 450 COPD 7 95% 127,261 120,818 Yes 76 660 COPD 6 95% 8,892 8,460 Yes 8 100 COPD 5 97% 8,266 7,996 No 22 100 Asthma 4 97% 39,932 38,416 No 72 600 Asthma 3 95% 12,826 12,195 Yes 18 172 Asthma 2 79% 398,296 316,420 No 147 1102 Asthma 1 Completion Compliance Expected Daily Diaries Received Daily Diaries eSense PiKo Sites Subjects Indication
  • 14.
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  • 16.