Leonard works in the agriculture industry and raises beef cattle. At 60 years of age, he has spent
most of his life working outdoors harvesting hay and tending to his herds. His wife was the first
to notice a change in his skin. One day, after taking off his shirt, she noticed a significant change
in the mole he had on his right shoulder. It not only was darker but was moist and appeared to
have been bleeding at one point. Surrounding the mole, his skin was red. His wife remembered
hearing stories of Leonard working on his fathers farm, spending long hours out in the hot sun
even though his father had gone into the barn to work during the hottest part of the day. She
insisted him go to the family physician to have it examined.
Tasks
Please address the following:
Leonards physician performed a biopsy on the lesion and told Leonard he suspected the growth
may be malignant melanoma. What cells are affected in this form of skin cancer?
How might his childhood exposures to the sun predispose him to this form of cancer?
How do UVA and UVB rays contribute to the process of oncogenesis in skin cells?
The mole on Leonards shoulder was a nevocellular nevus. What are the cellular composition and
appearance of this type of mole before it underwent malignant change?.
Leonard works in the agriculture industry and raises beef cattle. At.pdf
1. Leonard works in the agriculture industry and raises beef cattle. At 60 years of age, he has spent
most of his life working outdoors harvesting hay and tending to his herds. His wife was the first
to notice a change in his skin. One day, after taking off his shirt, she noticed a significant change
in the mole he had on his right shoulder. It not only was darker but was moist and appeared to
have been bleeding at one point. Surrounding the mole, his skin was red. His wife remembered
hearing stories of Leonard working on his fathers farm, spending long hours out in the hot sun
even though his father had gone into the barn to work during the hottest part of the day. She
insisted him go to the family physician to have it examined.
Tasks
Please address the following:
Leonards physician performed a biopsy on the lesion and told Leonard he suspected the growth
may be malignant melanoma. What cells are affected in this form of skin cancer?
How might his childhood exposures to the sun predispose him to this form of cancer?
How do UVA and UVB rays contribute to the process of oncogenesis in skin cells?
The mole on Leonards shoulder was a nevocellular nevus. What are the cellular composition and
appearance of this type of mole before it underwent malignant change?
