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Health problems in
female- including
abortion, infertility
and menopause
Presented by- Dr Asmita Poudel
MPH-2022
School of public health and
community medicine
BPKIHS
1
Contents
• Health problems- before, during and after pregnancy
• Women health issues
• Health problems in women (Abortion, Infertility, Menopause)
• Global scenario
• National scenario
• Types
• Causes
• Management
• Preventive measures
• References
2
Health problems of female
3
Before pregnancy During pregnancy During later age of life
Eating disorders (anorexia
nervosa, bulimia nervosa)
Hypertensive disorders(pre
eclampsia , eclampsia)
Osteoporosis
Cancer anemia Cancers
Road traffic injuries Gestational diabetes Mental health problems like
depression
Sexually transmitted infections hemorrhage Uterine prolapse
Anemia sepsis Cardiovascular diseases
Malnutrition abortion Road traffic injuries
Sexually transmitted infections
4
Women
health
issues
5
Premenstrual Syndrome (PMS)
Reproductive Health
Heart Disease
Breast and Cervical Cancer
Osteoporosis and Arthritis
Prenatal Health
HIV and Sexually-Transmitted Disease
Mental Health Illnesses
Aging and Getting Older
Insomnia and Sleep Disorders
Violence against women
Premenstrual
Syndrome (PMS)
• Most common problem that women face
year after year
• PMS affects 40% of women and usually
occurs in the last two weeks of the
menstrual cycle.
• PMS is painful and mentally taxing, but you
can do things to fight its effects.
• Consumption of carb-rich diet consisting of
lots of grains and veggies, exercise for at
least 30 minutes per day, three days a
week, include a broad range of vitamins and
minerals in daily diets, such as calcium,
magnesium, and vitamin B6.
6
Reproductive Health
• RH means Physical, mental and social health condition related to reproductive system, process and
function.
• Components of reproductive health
1. Family planning
2. Safe motherhood
3. Newborn care
4. Safe abortion service
5. Adolescent sexual and reproductive health
6. STI, HIV/AIDS
7. Problem of elderly women
8. Prevention and management of infertility
9. Gender based violence 7
Heart Disease
• CVD develops 7-10 years later in women than in men.
• Study shows that young women with oestrogen deficiency have more than 7 fold
increase in coronary artery risk.
• Oestrogen have regulating effect on lipids, inflammatory markers and coagulant
system
• Post menopausal women are at high risk ( total cholesterol and LDL increases but
HDL remains unaffected)
• After menopause body weight may increase and body fat distribution changes from
gyneoid to more android pattern with central obesity- risk factor for CHD
• Also obese women are more prone to type 2 DM.
• Women have smaller coronary arteries than men which makes angiography,
angioplasty and coronary bypass surgery more difficult to do.
• Regular exercise, eating healthy, abstaining from smoking, and lowering your stress
levels will reduce the risk of heart problems. 8
Breast and Cervical Cancer
• women should receive screenings for once they reach adulthood.
• Breast cancer and cervical cancer common
• The earlier you diagnose cancer, the better your odds are of beating it.
Osteoporosis and Arthritis
• The older we get, the more likely women are to contract osteoporosis or arthritis.
• Osteoporosis is a disease that weakens the bones and increases your risk of fractures.
• Arthritis, on the other hand, attacks the joints and results in painful inflammation around the joints.
• The best way to prevent arthritis is through early screenings and catching the problem before it
progresses.
• Osteoarthritis can be prevented through regular exercise, a diet heavy in vitamin D and calcium, and taking
additional supplements where necessary.
9
Prenatal Health
• The health care of pregnant women
• Pre natal health care is an important entry point for pregnant women to receive health promotion and
preventive information and services including iron supplementation, deworming tablet, tetanus injection, and
malaria prophylaxis.
• The availability of routine prenatal care, including prenatal screening and diagnosis, has played a part in
reducing the frequency of maternal death, miscarriages, birth defects, low birth weight, neonatal
infections and other preventable health problems.
• Government of Nepal (GoN) recommends focused antenatal visits at fourth, sixth, eighth, and ninth months
of pregnancy
HIV and Sexually-Transmitted Disease
• HIV, gonorrhea, syphilis, and chlamydia are some of the top STDs
• Using proper protection and engaging in safe sex is the best way to protect from these illnesses.
• Syphilis that goes untreated is responsible for hundreds of thousands of stillbirths and tens of thousands of
newborn deaths.
10
Mental Health Illnesses
• Problem for women of all ages.
• The stresses of everyday life combined with the anxiety of uncertainty
can result in depression, high anxiety, and feelings of hopelessness.
• Women are more likely to experience a mental health problem than men,
and suicide has become a leading cause of death in women under 60.
• If you begin feeling any signs of anxiety or depression, it’s important to
seek the help you need.
• Reducing the stress in your life will help, but you may require counseling
to repair your mental health and well-being completely.
11
Aging and Getting Older
• Aging is the one thing that seems to catch up to everyone no matter what.
• However, some women age much faster than others and feel its negative effects.
• Can prevent the painful symptoms of aging by maintaining a healthy lifestyle that includes diet, exercise,
and stress reduction.
• Keeping your heart, mind, and bones healthy is paramount to living a long and healthy life.
Insomnia and Sleep Disorders
• result of a high-stress lifestyle and a lack of a healthy diet.
• Sleep disorders often accompany anxiety and other mental illnesses.
• Medication and learning a sleep routine that works for you are the best ways to overcome insomnia and other
sleep disorders.
12
• Road traffic injuries are among the five leading causes of death for adolescent
girls and women of reproductive age in all WHO regions – except for South-East
Asia, where burns are the third leading cause of death. While many are the
result of cooking accidents, some are homicides or suicides, often associated
with violence by an intimate partner.
• Suicide is among the leading causes of death for women between the ages of 20
and 59 years globally and the second leading cause of death in the low- and
middle-income countries of the WHO Western Pacific Region.
• For women over 60 years of age in low-, middle- and high-income countries,
cardiovascular disease and stroke are major killers and causes of chronic
health problems. Another significant cause of death is chronic obstructive
pulmonary disease, which has been linked to women’s exposure to smoke and
indoor air pollution
• loss of vision – every year, more than 2.5 million older women go blind. Much of
this burden of disability could be avoided if they had access to the necessary
care, particularly surgery for cataracts.
• In low-income countries, trachoma is a significant, but preventable, cause of
blindness that affects women in particular. 13
14
The 10 leading causes of death for
women in the world (2015)
• 1. Ischemic heart disease
2. Stroke
3. Lower respiratory infections
4. Chronic obstructive pulmonary disease
5. Alzheimer’s disease and other dementias
6. Diabetes mellitus
7. Diarrhoeal disease
8. Breast cancer
9. Kidney diseases
10. Hypertensive heart diseases
15
16
Health Problems of Women above Forty Years
of Age in Rupandehi District of Nepal
17
International Journal of Health Sciences and Research 2013
•Abortion is
defined
as pregnancy
termination prior
to 20 weeks of
gestation. (WHO)
18
Introduction(1)
Introduction(2)
• Those who oppose abortion often argue that an embryo or fetus is a person
with a right to life, and thus equate abortion with murder.
• Those who support the legality of abortion often argue that it is part of
a woman's right to make decisions about her own body.
• Where abortion is illegal or highly restricted, women resort to unsafe means to
end unwanted pregnancies- self-inflicted abdominal and bodily trauma,
ingestion of dangerous chemicals, self-medication with a variety of
drugs, and reliance on unqualified abortion providers
• Also reported methods of unsafe, self-induced abortion include misuse
of misoprostol and insertion of non-surgical implements such as knitting needles
and clothes hangers into the uterus.
20
ABORTION
INDUCED
SURGICAL (up to 24
weeks)
DILATION AND
CURETTAGE WITH
SUCTION (less than
14 weeks)
DILATION AND
EVACUATION
(between 14 and 24
weeks)
MEDICAL (less than
11 weeks or that are
more than 15 weeks)
MISCARRIAGE
(before the 20th
week of pregnancy)
21
An abortion may occur spontaneously, called a miscarriage, or it may be brought on purposefully,
called an induced abortion.
Abortion generally refers to an induced abortion.
Spontaneous abortion/ miscarriage
• Spontaneous expulsion of the embryo or fetus from the uterus before the 20th week
of pregnancy, prior to the conceptus having developed sufficiently to live without maternal
support.
• An estimated 10 to 25 percent of recognized pregnancies are lost as a result of
miscarriage, with the risk of loss being highest in the first six weeks of pregnancy.
• Because many miscarriages occur prior to a woman knowing she is pregnant, the
actual prevalence of miscarriage is suspected to be higher than that reflected in the data
for clinically recognized cases
• Occurs for many reasons, including disease, trauma, genetic defect, or biochemical
incompatibility of mother and fetus.
• Missed abortion: a condition in which a fetus dies in the uterus but fails to be expelled.
22
Induced abortion
• Those abortions which are performed for reasons that fall into four general
categories:
• to preserve the life or physical or mental well-being of the mother;
• to prevent the completion of a pregnancy that has resulted from rape
or incest;
• to prevent the birth of a child with serious deformity, mental deficiency
or genetic abnormality; or
• to prevent a birth for social or economic reasons (such as the
extreme youth of the pregnant female or the sorely strained resources
of the family unit).
• When properly done, induced abortion is one of the safest procedures in
medicine 23
Surgical abortion
• In Surgical abortion the contents of the uterus are removed through the vagina.
• Different techniques are used depending on the length of the pregnancy.
1. Dilation and curettage (D and C) with suction
2. Dilation and evacuation (D and E)
• Dilation refers to widening the cervix. Different types of dilators may be used, depending
on how long the pregnancy has lasted and how many children the woman has had.
• If women wish to prevent future pregnancies, contraception, including
a copper or levonorgestrel-releasing intrauterine device (IUD), can be started as
soon as the abortion is completed.
• Hysterotomy- Surgical removal of the uterine contents, may be used during the second
trimester or later.
24
Medical abortion(1)
• Pregnancy (less than 11 weeks)- at home.
• Later in pregnancy- admitted to the hospital to take the drugs that will induce
labor.
• Drugs - mifepristone (RU 486), followed by a prostaglandin, such
as misoprostol.
• Practitioners confirm the completion of the abortion by one of the following:
• Ultrasonography
• A urine test to measure human chorionic gonadotropin (hCG) on the
day the drug is given and 1 week later (hCG is produced early in
pregnancy)
• At home -involves taking mifepristone tablet, followed by misoprostol taken 1
to 2 days later. The woman may take mifepristone and misoprostol on her own
or have a doctor give it to her. This regimen causes abortion in about
• 95% of pregnancies that have lasted 8 to 9 weeks
• 87 to 92% of pregnancies that have lasted 9 to 11 weeks
• If a medication abortion is unsuccessful, a surgical abortion may be required.
25
Medical abortion(2)
• Introduced in the late 20th century
• An artificial steroid that is closely related to the contraceptive hormone
norethnidrone.
• Works by blocking the action of the hormone progesterone, which is
needed to support the development of a fertilized egg.
• Mifepristone also makes the uterus more sensitive to the second drug that
is given (the prostaglandin)
• When ingested within weeks of conception, it effectively triggers the menstrual
cycle and flushes the fertilized egg out of the uterus.
RU
486 (mifepristone)
• Hormonelike substances that stimulate the uterus to contract.
• They may be used with mifepristone.
Prostaglandins
(misoprostol)
Global scenerio
27
According to center for reproductive rights 2021, fact sheet
28
257 million
women who
want to avoid
pregnancy are
not using safe,
modern methods
of contraception
172 million are
using no method
at all
121 million
unintended
pregnancies
happen
60 per cent of
unintended
pregnancies will
end in abortion
45 per cent of all
abortions are
unsafe.
29
26
24
23
20
fear and experience of side effect infrequent sex opposition to contraception breast feeding or post partum and not mensturatiing
Reasons for not using modern contraceptives ( UNFPA, 2022)
National Scenerio
• Half of women (51%) reported that they received services from an
authorized abortion facility. Less than one-third (31%) of women said
they went to a government health facility, while 27% went to a private
health facility. Over one-fourth (27%) of women had their abortion at
home (NDHS report 2016)
• The percentage of pregnancies ending in abortion is higher in urban
than in rural areas (11% and 7%, respectively).
• Maternal mortality in Nepal decreased from 548 deaths per 100,000
live births in 2000 to 258 deaths per 100,000 live births in 2015
30
• Abortion rate among women of reproductive age is 42 per 1000 women of
reproductive age. (15-49 yrs). (DOHS)
• The safe abortion service has slightly decreased in FY 2077/78 in
comparison to last FY 2076/77. Abortion statistics shows a decreasing
trend from FY 2074/75.
• Post abortion contraceptive uptake is 76%(FY 77/78) but 72%(FY 76/77),
but only 15% have used LARCPMs indicating women after abortion are
relying on less effective methods.
31
6666666666666666666666666666666666666666
666666666666666666666666666666666
32
TYPES OF ABORTION SERVICES USED BY ADOLESCENTS, FY 2073/74 TO FY 2077/78
72
17
7
4
Types of abortion practiced in Nepal according to
NDHS 2016
Medical abortion Mannual vacuum aspiration D and E or D and C Others 33
71
19
5
5
Types of provider
Doctor, nurse, or auxiliary nurse midwife Pharmacist or medical shop
HA or other health worker Others
34
35
PERCENTAGE OF PREGNANCIES TERMINATE AMONG EXPECTED PREGNANCIES
The abortion law allows women to terminate their
pregnancy under the following conditions:-
• Fetus up to 12 weeks, with the consent of the pregnant woman
• Fetus up to 28 weeks , as per consent of such woman, after the opinion of the licensed doctor that
there may be danger upon the life of the pregnant woman or her physical or mental health may
deteriorate or disabled infant may be born in case the abortion is not performed.
• fetus remained due to rape or incest, up to 28 weeks with the consent of pregnant woman.
• Fetus up to 28 weeks with the consent of the woman who is suffering from H.I.V. or other incurable
diseases of such nature.
• Not to get abortion conducted forcefully.
• Not to commit abortion upon identifying sex.
• Maintain confidentiality.
(The Right to Safe Motherhood and Reproductive Health Act, 2075 and safe abortion service program
management guideline 2078) 36
Safe abortion services
• Nepal made abortion legal in September 2002, the procedural order
was passed in 2003, and the first ever comprehensive abortion care
service was started at the maternity hospital, Kathmandu, in March
2004.
• First-trimester surgical abortions were made available throughout the
country in 2004.
• Second-trimester abortion training began in 2007, and medical
abortions were introduced in 2009.
• The licensed health worker who has fulfilled the prescribed standards
and qualification shall have to provide the pregnant woman with safe
abortion service in the licensed health institution.
• The pregnant woman who wants to obtain the safe abortion service
shall have to give consent in the prescribed format to the health
institution which has obtained a license, or to the health worker who
has obtained a license. 37
• Medical abortion services are expanded at health post with additional training to the SBA.
• Comprehensive abortion care (manual vacuum aspiration [MVA]) services are available in all 77 district hospitals
and majority of PHCCs.
• A total of 912 sites for MA, 604 sites for both MA and MVA and 22 sites for abortion in/after second trimester
were listed to provide safe abortion services till the FY 2076/77.
• Similarly, a total of 1833 ANMs for MA, 743 nurses and 1853 doctors (MBBS) for MA/MVA and 92 OBGYN or
MDGPs have been listed for in/after second trimester safe abortion services till the FY 2076 /77.
• As per government policy, auxiliary nurse midwives are allowed to provide medical abortion care only up to 10
weeks’ gestation
• Staff nurses are allowed to perform both manual vacuum aspiration (MVA) and medical abortion up to 10 weeks’
gestation
• MBBS doctors are allowed to perform MVA up to 12 weeks
• Obstetrician-gynecologists and general practitioners are allowed to perform abortion at 13–28 weeks’ gestation
(second-trimester abortions).
38
Organizations working for safe abortion in
nepal
• Ipass Nepal
• Population services international Nepal
• Marie stopes international
• Fpan
• WHO Nepal
• UNFPA
39
Components of comprehensive abortion care
• Comprehensive abortion care is included in the list of essential
health care services published by WHO in 2020
• FWD has defined the four key components of comprehensive
abortion care as:
Pre and post counselling on safe abortion method and post-
abortion contraceptive methods.
Termination of pregnancies as per the national protocol.
Diagnosis and treatment of existing reproductive tract infection and
Provide contraceptive methods as per informed choice and follow up
for post abortion complication management.
40
Consequences of inaccessible quality
abortion care
• risks to women’s physical and mental well-being
• risks violating a range of human rights of women and girls
• Physical health risks associated with unsafe abortion include:
incomplete abortion (failure to remove or expel all pregnancy tissue
from the uterus);
haemorrhage (heavy bleeding);
infection;
uterine perforation (caused when the uterus is pierced by a sharp
object); and
damage to the genital tract and internal organs as a consequence of
inserting dangerous objects into the vagina or anus.
41
42
Introduction
• Infertility is a disease of the reproductive system defined by the
failure to achieve a clinical pregnancy after 12 months or more of
regular unprotected sexual intercourse (and there is no other
reason, such as breastfeeding or postpartum amenorrhea) (WHO)
• In the male reproductive system, infertility is most commonly caused
by problems in the ejection of semen, absence or low levels of
sperm, or abnormal morphology and motility of the sperm.
• In the female reproductive system, infertility may be caused by a
range of abnormalities of the ovaries, uterus, fallopian tubes,
and the endocrine system.
43
• Infertility can be primary or secondary.
• Primary infertility is when a pregnancy has never been achieved by
a person, and secondary infertility is when at least one prior
pregnancy has been achieved
• Fertility care encompasses the prevention, diagnosis and
treatment of infertility.
• Equal and equitable access to fertility care remains a challenge in
most countries; particularly in low and middle-income countries.
• Fertility care is rarely prioritized in national universal health
coverage benefit packages.
44
Risk factors
• Age. The quality and quantity of a woman's eggs begin to decline with
age. In the mid-30s, the rate of follicle loss speeds, resulting in fewer and
poorer quality eggs. This makes conception more difficult, and
increases the risk of miscarriage.
• Smoking. Besides damaging your cervix and fallopian tubes, smoking
increases your risk of miscarriage and ectopic pregnancy
• Weight. Being overweight or significantly underweight may affect
ovulation.
• Sexual history. Sexually transmitted infections such as chlamydia and
gonorrhea can damage the fallopian tubes.
• Alcohol. Excess alcohol consumption can reduce fertility.
45
Symptoms
• A menstrual cycle that's too long (35 days or more), too short (less than 21
days), irregular or absent can mean that you're not ovulating.
• There might be no other signs or symptoms.
When to see a doctor
• Up to age 35, most doctors recommend trying to get pregnant for at least a year
before testing or treatment.
• If you're between 35 and 40, discuss your concerns with your doctor after six
months of trying.
• If you're older than 40, your doctor might suggest testing or treatment
46
FEMALE REPRODUCTIVE ORGAN FERTILIZATION AND IMPLANTATION
47
What causes infertility?
• Tubal disorders such as blocked fallopian tubes→ caused by untreated sexually transmitted
infections (STIs) or complications of unsafe abortion, postpartum sepsis or abdominal/pelvic
surgery;
• Uterine disorders→ which could be inflammatory in nature (endometriosis), congenital in nature
(septate uterus), or benign in nature (fibroids);
• Disorders of the ovaries→ such as polycystic ovarian syndrome and other follicular disorders;
• Disorders of the endocrine system→ pituitary cancers and hypopituitarism causing
imbalances of reproductive hormones.
• Environmental and lifestyle factors→ smoking, excessive alcohol intake, obesity. In addition,
exposure to environmental pollutants and toxins can be directly toxic to gametes (eggs and sperm),
resulting in their decreased numbers and poor quality, leading to infertility
• In some cases, the cause of infertility is never found. A combination of several minor factors in
both partners could cause unexplained fertility problems. 48
Diagnosis of female infertility
• Physical examination – including medical history
• Blood tests – to check for the presence of ovulation hormones
• Pap test
• Laparoscopy – a ‘keyhole’ surgical procedure in which an instrument is inserted
through a small incision in the abdomen so that the reproductive organs can be
examined
• Hysteroscopy: In this test, a device called a hysteroscope (a flexible, thin device
with a camera) is inserted into the vagina and through the cervix. The healthcare
provider moves it into the uterus to view the inside of the organ.
• Ultrasound scans – to check for the presence of fibroids.
49
Treatment for female
infertility
• Surgery
• Ovulation induction (using hormone
treatment)
• Artificial insemination (IUI)
• Assisted reproductive technologies
(ART) including in-vitro fertilisation
(IVF) and intracytoplasmic sperm
injection (ICSI)
50
Surgery for female infertility
INDICATIONS
• Fibroids – non-malignant tumours growing inside the uterus
• Polyps – overgrowths of the uterine lining (endometrium)
• Endometriosis – the growth of endometrial tissue outside the
uterus, which can block the fallopian tubes
• Abnormalities of the uterus – such as a uterine septum
• Ovarian cysts – which can be drained or removed.
51
Ovulation induction for female infertility
• Used if a woman is not ovulating or not ovulating regularly.
• It involves taking a hormone medication (tablets or
injections) to stimulate ovulation.
• The response to the hormones is monitored with ultrasound and
when the time is right, an injection is given to trigger
ovulation.
• Timing intercourse to coincide with ovulation offers the chance
of pregnancy.
52
Artificial insemination or IUI
• It involves insertion of the male partner’s (or a donor’s) sperm
into a woman’s uterus at or just before the time of ovulation.
• IUI can help couples with so called unexplained infertility or
couples where the male partner has minor sperm
abnormalities.
• IUI can be performed during a natural menstrual cycle, or in
combination with ovulation induction (OI) if the woman has
irregular menstrual cycles.
• If a pregnancy is not achieved after a few IUI attempts, IVF or
intracytoplasmic sperm injection (ICSI) may be needed.
53
In-vitro fertilization
Assisted reproductive technologies (ART) includes in-vitro fertilisation (IVF) and intracytoplasmic sperm
injection (ICSI), which is used when there is a male cause of infertility.
ART involves hormone stimulation to make the ovaries produce 10 to 15 eggs rather than the one which
normally matures every month.
When the eggs are ‘ready’ they are retrieved in an ultrasound-guided procedure.
In the case of IVF the collected eggs are then mixed with sperm from the male partner or a donor, and in
the case of ICSI each egg is injected with a single sperm.
Two to 5 days later an embryo is transferred to the woman’s uterus using a thin tube that is inserted
through the cervix. If there are more embryos than needed, these can be frozen for future use.
54
IVF success rates
• Under 34: 44 per cent chance of a live
birth
• 35-39: 31 per cent chance of a live
birth
• 40-44: 11 per cent chance of a live
birth
• 44 and above: one per cent chance of
a live birth.
• (Research using the Australian and New
Zealand Assisted Reproduction Database,
calculated the chance of a woman having a
baby from her first cycle of IVF according to her
age)
55
56
Donor conception is the process of having a baby using donated sperm, eggs or embryos through
self-insemination or fertility treatment such as IVF.
Sometimes it involves surrogacy, too. Donor conception involves a donor (the person donating sperm,
eggs or an embryo) and recipient parent(s) who receive the donation. A child born as a result of the
donation is known as a donor-conceived person.
• There are many reasons why donor sperm, eggs or embryos may be needed.
 Donor sperm:
• a male partner does not produce any sperm or normal sperm
• there is a high risk of a man passing on a genetic disease or abnormality to a child.
• by single women and women in same-sex relationships. The process of donor insemination is the same as IUI.
• If the woman also has an infertility problem, donor sperm can be used in IVF treatment.
 Donor eggs
• a woman doesn’t produce eggs or her eggs are of low quality.
• a woman has experienced several miscarriages, or
• there is a high risk of the woman passing on a genetic disease or abnormality to a child.
 Donor embryos
• Donor embryos can be used if a person or couple requires both donor sperm and donor eggs to achieve a pregnancy. Although rare, some people
who have frozen embryos that they don’t need, choose to donate them for someone else to use.
57
Surrogacy
• Surrogacy involves a woman (the surrogate) carrying a child for
another person or couple with the intention of giving the child to that
person or couple after birth.
• The supreme court’s final verdict announced on December 12, 2016,
and holds that surrogacy is legal for infertile married couples but
illegal for singles, transgender and foreign nationals.
• It’s a popular option for male same-sex couples who want to have a
family and also can be used by people who are single in other
countries.
 Traditional surrogacy
• The surrogate provides her own egg, which is inseminated with the
parent’s sperm. This can be done using (IVF) or artificial insemination.
In this case, the baby is biologically related to the surrogate.
 Gestational surrogacy
• In this type of pregnancy, an embryo is transferred into the
surrogate’s uterus. The embryo is formed from the egg and sperm
of the intended parents or from donors, using IVF. 58
Risks of
assisted
reproductive
technologies
59
Ovarian hyperstimulation
syndrome (OHSS)
an increased incidence of
multiple pregnancies
an increased risk of premature
labour and low birth weight
an increased risk of caesarean
delivery
Global scenerio
• This problem was able to draw the attention of government leaders and
reproductive health experts in ICPD, 1994. This conference recommended
all members countries to include infertility as part of their reproductive
health care program.
• 48 million couples and 186 million individuals live with infertility, half of
these couples are living in Sub-Saharan Africa (SSA) and South
Asia globally. (WHO)
• 1 in 4 couples in developing countries is affected by infertility. (WHO,
2004)
• The use of assisted reproductive technology (ART) by infertile couples is
increasing by 5% to 10% per year.
• Nearly 2% of live births in the U.S. are a result of assisted reproductive
technology. (CDC, 2017)
60
61
Causes of infertility amongst couples visited
at infertility centre Kathmandu Nepal
62
National Level Advocacy Workshop On Infertility: Causes
And Consequences Of Violence Against Women
• WOREC in support of Swiss Network for International Studies and Graduate Institute of
International and Development studies Geneva conducted National Advocacy Workshop on
Infertility: January 27, 2020.
• The main objective of the workshop was to explore the perception of infertility, its causes and
consequences and health-seeking behavior among women and their husbands in order to
develop a strategy for action and policy setting.
• Conclusions
• Among all causes of infertility in the global south, it has been seen that 50 percent of the problem
lies within men whereas 90 percent of burden is borne by the women.
• Men are also victimized because of infertility and considered impotent (Napunsak). (a/c study in
2018)
63
• Infertility is a pretext of polygamy in all ethnicity whereas the social stigma of infertility is high among Brahmin
and Chettri.
• Depression and suicidal attempts are high in infertile women so it is better not to ask any couple when are we
going to hear good news? When I will get the chance to become an Aunt or Uncle and so on.
• Infertility has various dimensions like bio-medical, social, science and technology. The issue of infertility
should not be left alone with bio-medical treatment rather it should go clubbing with a social dimension too.
• Safe Motherhood Act 2075, has also incorporated the issue of infertility as one of the reproductive morbidities
64
65
Introduction
• Menopause is the time that marks the end of menstrual cycles in women. It's diagnosed after you've
gone 12 months without a menstrual period.
• Most women experience menopause between the ages of 45 and 55 years as a natural part of biological
ageing.
• Some women experience menopause earlier (before 40 years of age). This ‘premature menopause’
may be because of certain chromosomal abnormalities, autoimmune disorders, or other unknown
causes.
• Menopause is caused by the loss of ovarian follicular function and a decline in circulating blood
oestrogen levels.
• Menopause can affect physical, emotional, mental and social well-being.
• Menopause can also be induced as a consequence of surgical procedures that involve removal of
both ovaries or medical interventions that cause cessation of ovarian function (for example radiation
therapy or chemotherapy).
66
Stages of menopause
• Perimenopause: This is the transitional
time that starts before menopause and
includes the 12 months after person’s last
period.
• Menopause: This starts either after 12
months of the last period or when
menstruation has stopped for a clinical
reason, such as the removal of the
ovaries.
• Postmenopause: Postmeopause refers
to the years after menopause, although it
can be difficult to know when menopause
finished and postmenopause starts.
67
68
Complications
After menopause, your risk of certain medical conditions increases.
• Heart and blood vessel (cardiovascular) disease. When your estrogen levels decline, your risk of cardiovascular disease increases.
For example, blood pressure, LDL and triglycerides tend to go up after menopause. (Nearly a third of women develop cardiovascular
disease, the AHA says)
• Osteoporosis. This condition causes bones to become brittle and weak, leading to an increased risk of fractures. Women are 4 times as
likely as men to develop osteoporosis
• Urinary incontinence. As the tissues of your vagina and urethra lose elasticity, you may experience frequent, sudden, strong urges to
urinate, followed by an involuntary loss of urine (urge incontinence), or the loss of urine with coughing, laughing or lifting (stress
incontinence). You may have urinary tract infections more often.
• Weakening of the pelvic support structures. increasing the risk of pelvic organ prolapse due to Loss of bone
• Sexual function. Vaginal dryness from decreased moisture production and loss of elasticity can cause discomfort and slight bleeding
during sexual intercourse
• Weight gain because metabolism slows.
• Skin: The decrease in estrogen, as well as aging itself, causes a decrease in the amount of collagen (a protein that makes skin strong)
and elastin (a protein that makes skin elastic). Thus, the skin may become thinner, drier, less elastic, and more vulnerable to injury.
69
LGBTQIA+ and menopause
• Menopause can affect anyone who is born with ovaries.
• If a person starts taking supplementary testosterone as part of
their transition, they may experience menopause symptoms when
their ovaries stop producing eggs.
• The symptoms of menopause will be the same as those of
cisgender women.
• It is essential that transgender people have access to healthcare
providers who understand their needs and can address them
effectively.
70
Menopausal Health Status of
Nepalese Women
JNMA 2017
71
Treatments
72
References
1. https://www.msdmanuals.com/home/women-s-health-
issues/family-planning/abortion
2. acog.org/advocacy/facts-are-important/abortion-is-healthcare
3. https://www.acog.org/clinical-information/policy-and-position-
statements/statements-of-policy/2022/abortion-policy
4. https://www.who.int/news-room/fact-sheets/detail/abortion
5. https://reproductive-health-
journal.biomedcentral.com/articles/10.1186/s12978-019-0755-0
6. https://en.wikipedia.org/wiki/Abortion
7. https://www.britannica.com/science/abortion-pregnancy
73
8. Raymond EG, Grimes DA (February 2012.. "The comparative safety of legal induced abortion
and childbirth in the United States
9. Bearak J, Popinchalk A, Ganatra B, Moller A-B, Tunçalp Ö, Beavin C et al. Unintended
pregnancy and abortion by income, region, and the legal status of abortion: estimates from a
comprehensive model for 1990–2019. Lancet Glob Health. 2020 Sep; 8(9):e1152-e1161. doi:
10.1016/S2214-109X(20)30315-6
10. Ganatra B, Gerdts C, Rossier C, Johnson Jr B R, Tuncalp Ö, Assifi A et al. Global, regional, and
subregional classification of abortions by safety, 2010–14: estimates from a Bayesian
hierarchical model. The Lancet. 2017 Sep
11. Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J et al. Global causes of maternal
death: a WHO systematic analysis. Lancet Glob Health. 2014 Jun; 2(6):e323-33.
12. Singh S, Maddow-Zimet I. Facility-based treatment for medical complications resulting from
unsafe pregnancy termination in the developing world, 2012: a review of evidence from 26
countries. BJOG 2015; published online Aug 19. DOI:10.1111/1471-0528.13552.
13. Vlassoff et al. Economic impact of unsafe abortion-related morbidity and mortality: evidence and
estimation challenges. Brighton, Institute of Development Studies, 2008 (IDS Research Reports
59).
74
1. https://www.who.int/news-room/fact-sheets/detail/infertility
2. https://www.mayoclinic.org/diseases-conditions/female-
infertility/symptoms-causes/syc-20354308
3. https://www.betterhealth.vic.gov.au/health/conditionsandtreat
ments/infertility-in-women
4. https://www.singlecare.com/blog/news/infertility-statistics/
• https://www.mayoclinic.org/diseases-
conditions/menopause/symptoms-causes/syc-20353397
• https://www.who.int/news-room/fact-sheets/detail/menopause
• https://www.healthline.com/health/menopause#outlook
75
76

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Health problems in female-including abortion, infertility and menopause.pptx

  • 1. Health problems in female- including abortion, infertility and menopause Presented by- Dr Asmita Poudel MPH-2022 School of public health and community medicine BPKIHS 1
  • 2. Contents • Health problems- before, during and after pregnancy • Women health issues • Health problems in women (Abortion, Infertility, Menopause) • Global scenario • National scenario • Types • Causes • Management • Preventive measures • References 2
  • 3. Health problems of female 3 Before pregnancy During pregnancy During later age of life Eating disorders (anorexia nervosa, bulimia nervosa) Hypertensive disorders(pre eclampsia , eclampsia) Osteoporosis Cancer anemia Cancers Road traffic injuries Gestational diabetes Mental health problems like depression Sexually transmitted infections hemorrhage Uterine prolapse Anemia sepsis Cardiovascular diseases Malnutrition abortion Road traffic injuries Sexually transmitted infections
  • 4. 4
  • 5. Women health issues 5 Premenstrual Syndrome (PMS) Reproductive Health Heart Disease Breast and Cervical Cancer Osteoporosis and Arthritis Prenatal Health HIV and Sexually-Transmitted Disease Mental Health Illnesses Aging and Getting Older Insomnia and Sleep Disorders Violence against women
  • 6. Premenstrual Syndrome (PMS) • Most common problem that women face year after year • PMS affects 40% of women and usually occurs in the last two weeks of the menstrual cycle. • PMS is painful and mentally taxing, but you can do things to fight its effects. • Consumption of carb-rich diet consisting of lots of grains and veggies, exercise for at least 30 minutes per day, three days a week, include a broad range of vitamins and minerals in daily diets, such as calcium, magnesium, and vitamin B6. 6
  • 7. Reproductive Health • RH means Physical, mental and social health condition related to reproductive system, process and function. • Components of reproductive health 1. Family planning 2. Safe motherhood 3. Newborn care 4. Safe abortion service 5. Adolescent sexual and reproductive health 6. STI, HIV/AIDS 7. Problem of elderly women 8. Prevention and management of infertility 9. Gender based violence 7
  • 8. Heart Disease • CVD develops 7-10 years later in women than in men. • Study shows that young women with oestrogen deficiency have more than 7 fold increase in coronary artery risk. • Oestrogen have regulating effect on lipids, inflammatory markers and coagulant system • Post menopausal women are at high risk ( total cholesterol and LDL increases but HDL remains unaffected) • After menopause body weight may increase and body fat distribution changes from gyneoid to more android pattern with central obesity- risk factor for CHD • Also obese women are more prone to type 2 DM. • Women have smaller coronary arteries than men which makes angiography, angioplasty and coronary bypass surgery more difficult to do. • Regular exercise, eating healthy, abstaining from smoking, and lowering your stress levels will reduce the risk of heart problems. 8
  • 9. Breast and Cervical Cancer • women should receive screenings for once they reach adulthood. • Breast cancer and cervical cancer common • The earlier you diagnose cancer, the better your odds are of beating it. Osteoporosis and Arthritis • The older we get, the more likely women are to contract osteoporosis or arthritis. • Osteoporosis is a disease that weakens the bones and increases your risk of fractures. • Arthritis, on the other hand, attacks the joints and results in painful inflammation around the joints. • The best way to prevent arthritis is through early screenings and catching the problem before it progresses. • Osteoarthritis can be prevented through regular exercise, a diet heavy in vitamin D and calcium, and taking additional supplements where necessary. 9
  • 10. Prenatal Health • The health care of pregnant women • Pre natal health care is an important entry point for pregnant women to receive health promotion and preventive information and services including iron supplementation, deworming tablet, tetanus injection, and malaria prophylaxis. • The availability of routine prenatal care, including prenatal screening and diagnosis, has played a part in reducing the frequency of maternal death, miscarriages, birth defects, low birth weight, neonatal infections and other preventable health problems. • Government of Nepal (GoN) recommends focused antenatal visits at fourth, sixth, eighth, and ninth months of pregnancy HIV and Sexually-Transmitted Disease • HIV, gonorrhea, syphilis, and chlamydia are some of the top STDs • Using proper protection and engaging in safe sex is the best way to protect from these illnesses. • Syphilis that goes untreated is responsible for hundreds of thousands of stillbirths and tens of thousands of newborn deaths. 10
  • 11. Mental Health Illnesses • Problem for women of all ages. • The stresses of everyday life combined with the anxiety of uncertainty can result in depression, high anxiety, and feelings of hopelessness. • Women are more likely to experience a mental health problem than men, and suicide has become a leading cause of death in women under 60. • If you begin feeling any signs of anxiety or depression, it’s important to seek the help you need. • Reducing the stress in your life will help, but you may require counseling to repair your mental health and well-being completely. 11
  • 12. Aging and Getting Older • Aging is the one thing that seems to catch up to everyone no matter what. • However, some women age much faster than others and feel its negative effects. • Can prevent the painful symptoms of aging by maintaining a healthy lifestyle that includes diet, exercise, and stress reduction. • Keeping your heart, mind, and bones healthy is paramount to living a long and healthy life. Insomnia and Sleep Disorders • result of a high-stress lifestyle and a lack of a healthy diet. • Sleep disorders often accompany anxiety and other mental illnesses. • Medication and learning a sleep routine that works for you are the best ways to overcome insomnia and other sleep disorders. 12
  • 13. • Road traffic injuries are among the five leading causes of death for adolescent girls and women of reproductive age in all WHO regions – except for South-East Asia, where burns are the third leading cause of death. While many are the result of cooking accidents, some are homicides or suicides, often associated with violence by an intimate partner. • Suicide is among the leading causes of death for women between the ages of 20 and 59 years globally and the second leading cause of death in the low- and middle-income countries of the WHO Western Pacific Region. • For women over 60 years of age in low-, middle- and high-income countries, cardiovascular disease and stroke are major killers and causes of chronic health problems. Another significant cause of death is chronic obstructive pulmonary disease, which has been linked to women’s exposure to smoke and indoor air pollution • loss of vision – every year, more than 2.5 million older women go blind. Much of this burden of disability could be avoided if they had access to the necessary care, particularly surgery for cataracts. • In low-income countries, trachoma is a significant, but preventable, cause of blindness that affects women in particular. 13
  • 14. 14
  • 15. The 10 leading causes of death for women in the world (2015) • 1. Ischemic heart disease 2. Stroke 3. Lower respiratory infections 4. Chronic obstructive pulmonary disease 5. Alzheimer’s disease and other dementias 6. Diabetes mellitus 7. Diarrhoeal disease 8. Breast cancer 9. Kidney diseases 10. Hypertensive heart diseases 15
  • 16. 16
  • 17. Health Problems of Women above Forty Years of Age in Rupandehi District of Nepal 17 International Journal of Health Sciences and Research 2013
  • 18. •Abortion is defined as pregnancy termination prior to 20 weeks of gestation. (WHO) 18
  • 20. Introduction(2) • Those who oppose abortion often argue that an embryo or fetus is a person with a right to life, and thus equate abortion with murder. • Those who support the legality of abortion often argue that it is part of a woman's right to make decisions about her own body. • Where abortion is illegal or highly restricted, women resort to unsafe means to end unwanted pregnancies- self-inflicted abdominal and bodily trauma, ingestion of dangerous chemicals, self-medication with a variety of drugs, and reliance on unqualified abortion providers • Also reported methods of unsafe, self-induced abortion include misuse of misoprostol and insertion of non-surgical implements such as knitting needles and clothes hangers into the uterus. 20
  • 21. ABORTION INDUCED SURGICAL (up to 24 weeks) DILATION AND CURETTAGE WITH SUCTION (less than 14 weeks) DILATION AND EVACUATION (between 14 and 24 weeks) MEDICAL (less than 11 weeks or that are more than 15 weeks) MISCARRIAGE (before the 20th week of pregnancy) 21 An abortion may occur spontaneously, called a miscarriage, or it may be brought on purposefully, called an induced abortion. Abortion generally refers to an induced abortion.
  • 22. Spontaneous abortion/ miscarriage • Spontaneous expulsion of the embryo or fetus from the uterus before the 20th week of pregnancy, prior to the conceptus having developed sufficiently to live without maternal support. • An estimated 10 to 25 percent of recognized pregnancies are lost as a result of miscarriage, with the risk of loss being highest in the first six weeks of pregnancy. • Because many miscarriages occur prior to a woman knowing she is pregnant, the actual prevalence of miscarriage is suspected to be higher than that reflected in the data for clinically recognized cases • Occurs for many reasons, including disease, trauma, genetic defect, or biochemical incompatibility of mother and fetus. • Missed abortion: a condition in which a fetus dies in the uterus but fails to be expelled. 22
  • 23. Induced abortion • Those abortions which are performed for reasons that fall into four general categories: • to preserve the life or physical or mental well-being of the mother; • to prevent the completion of a pregnancy that has resulted from rape or incest; • to prevent the birth of a child with serious deformity, mental deficiency or genetic abnormality; or • to prevent a birth for social or economic reasons (such as the extreme youth of the pregnant female or the sorely strained resources of the family unit). • When properly done, induced abortion is one of the safest procedures in medicine 23
  • 24. Surgical abortion • In Surgical abortion the contents of the uterus are removed through the vagina. • Different techniques are used depending on the length of the pregnancy. 1. Dilation and curettage (D and C) with suction 2. Dilation and evacuation (D and E) • Dilation refers to widening the cervix. Different types of dilators may be used, depending on how long the pregnancy has lasted and how many children the woman has had. • If women wish to prevent future pregnancies, contraception, including a copper or levonorgestrel-releasing intrauterine device (IUD), can be started as soon as the abortion is completed. • Hysterotomy- Surgical removal of the uterine contents, may be used during the second trimester or later. 24
  • 25. Medical abortion(1) • Pregnancy (less than 11 weeks)- at home. • Later in pregnancy- admitted to the hospital to take the drugs that will induce labor. • Drugs - mifepristone (RU 486), followed by a prostaglandin, such as misoprostol. • Practitioners confirm the completion of the abortion by one of the following: • Ultrasonography • A urine test to measure human chorionic gonadotropin (hCG) on the day the drug is given and 1 week later (hCG is produced early in pregnancy) • At home -involves taking mifepristone tablet, followed by misoprostol taken 1 to 2 days later. The woman may take mifepristone and misoprostol on her own or have a doctor give it to her. This regimen causes abortion in about • 95% of pregnancies that have lasted 8 to 9 weeks • 87 to 92% of pregnancies that have lasted 9 to 11 weeks • If a medication abortion is unsuccessful, a surgical abortion may be required. 25
  • 26. Medical abortion(2) • Introduced in the late 20th century • An artificial steroid that is closely related to the contraceptive hormone norethnidrone. • Works by blocking the action of the hormone progesterone, which is needed to support the development of a fertilized egg. • Mifepristone also makes the uterus more sensitive to the second drug that is given (the prostaglandin) • When ingested within weeks of conception, it effectively triggers the menstrual cycle and flushes the fertilized egg out of the uterus. RU 486 (mifepristone) • Hormonelike substances that stimulate the uterus to contract. • They may be used with mifepristone. Prostaglandins (misoprostol)
  • 27. Global scenerio 27 According to center for reproductive rights 2021, fact sheet
  • 28. 28
  • 29. 257 million women who want to avoid pregnancy are not using safe, modern methods of contraception 172 million are using no method at all 121 million unintended pregnancies happen 60 per cent of unintended pregnancies will end in abortion 45 per cent of all abortions are unsafe. 29 26 24 23 20 fear and experience of side effect infrequent sex opposition to contraception breast feeding or post partum and not mensturatiing Reasons for not using modern contraceptives ( UNFPA, 2022)
  • 30. National Scenerio • Half of women (51%) reported that they received services from an authorized abortion facility. Less than one-third (31%) of women said they went to a government health facility, while 27% went to a private health facility. Over one-fourth (27%) of women had their abortion at home (NDHS report 2016) • The percentage of pregnancies ending in abortion is higher in urban than in rural areas (11% and 7%, respectively). • Maternal mortality in Nepal decreased from 548 deaths per 100,000 live births in 2000 to 258 deaths per 100,000 live births in 2015 30
  • 31. • Abortion rate among women of reproductive age is 42 per 1000 women of reproductive age. (15-49 yrs). (DOHS) • The safe abortion service has slightly decreased in FY 2077/78 in comparison to last FY 2076/77. Abortion statistics shows a decreasing trend from FY 2074/75. • Post abortion contraceptive uptake is 76%(FY 77/78) but 72%(FY 76/77), but only 15% have used LARCPMs indicating women after abortion are relying on less effective methods. 31
  • 33. 72 17 7 4 Types of abortion practiced in Nepal according to NDHS 2016 Medical abortion Mannual vacuum aspiration D and E or D and C Others 33
  • 34. 71 19 5 5 Types of provider Doctor, nurse, or auxiliary nurse midwife Pharmacist or medical shop HA or other health worker Others 34
  • 35. 35 PERCENTAGE OF PREGNANCIES TERMINATE AMONG EXPECTED PREGNANCIES
  • 36. The abortion law allows women to terminate their pregnancy under the following conditions:- • Fetus up to 12 weeks, with the consent of the pregnant woman • Fetus up to 28 weeks , as per consent of such woman, after the opinion of the licensed doctor that there may be danger upon the life of the pregnant woman or her physical or mental health may deteriorate or disabled infant may be born in case the abortion is not performed. • fetus remained due to rape or incest, up to 28 weeks with the consent of pregnant woman. • Fetus up to 28 weeks with the consent of the woman who is suffering from H.I.V. or other incurable diseases of such nature. • Not to get abortion conducted forcefully. • Not to commit abortion upon identifying sex. • Maintain confidentiality. (The Right to Safe Motherhood and Reproductive Health Act, 2075 and safe abortion service program management guideline 2078) 36
  • 37. Safe abortion services • Nepal made abortion legal in September 2002, the procedural order was passed in 2003, and the first ever comprehensive abortion care service was started at the maternity hospital, Kathmandu, in March 2004. • First-trimester surgical abortions were made available throughout the country in 2004. • Second-trimester abortion training began in 2007, and medical abortions were introduced in 2009. • The licensed health worker who has fulfilled the prescribed standards and qualification shall have to provide the pregnant woman with safe abortion service in the licensed health institution. • The pregnant woman who wants to obtain the safe abortion service shall have to give consent in the prescribed format to the health institution which has obtained a license, or to the health worker who has obtained a license. 37
  • 38. • Medical abortion services are expanded at health post with additional training to the SBA. • Comprehensive abortion care (manual vacuum aspiration [MVA]) services are available in all 77 district hospitals and majority of PHCCs. • A total of 912 sites for MA, 604 sites for both MA and MVA and 22 sites for abortion in/after second trimester were listed to provide safe abortion services till the FY 2076/77. • Similarly, a total of 1833 ANMs for MA, 743 nurses and 1853 doctors (MBBS) for MA/MVA and 92 OBGYN or MDGPs have been listed for in/after second trimester safe abortion services till the FY 2076 /77. • As per government policy, auxiliary nurse midwives are allowed to provide medical abortion care only up to 10 weeks’ gestation • Staff nurses are allowed to perform both manual vacuum aspiration (MVA) and medical abortion up to 10 weeks’ gestation • MBBS doctors are allowed to perform MVA up to 12 weeks • Obstetrician-gynecologists and general practitioners are allowed to perform abortion at 13–28 weeks’ gestation (second-trimester abortions). 38
  • 39. Organizations working for safe abortion in nepal • Ipass Nepal • Population services international Nepal • Marie stopes international • Fpan • WHO Nepal • UNFPA 39
  • 40. Components of comprehensive abortion care • Comprehensive abortion care is included in the list of essential health care services published by WHO in 2020 • FWD has defined the four key components of comprehensive abortion care as: Pre and post counselling on safe abortion method and post- abortion contraceptive methods. Termination of pregnancies as per the national protocol. Diagnosis and treatment of existing reproductive tract infection and Provide contraceptive methods as per informed choice and follow up for post abortion complication management. 40
  • 41. Consequences of inaccessible quality abortion care • risks to women’s physical and mental well-being • risks violating a range of human rights of women and girls • Physical health risks associated with unsafe abortion include: incomplete abortion (failure to remove or expel all pregnancy tissue from the uterus); haemorrhage (heavy bleeding); infection; uterine perforation (caused when the uterus is pierced by a sharp object); and damage to the genital tract and internal organs as a consequence of inserting dangerous objects into the vagina or anus. 41
  • 42. 42
  • 43. Introduction • Infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse (and there is no other reason, such as breastfeeding or postpartum amenorrhea) (WHO) • In the male reproductive system, infertility is most commonly caused by problems in the ejection of semen, absence or low levels of sperm, or abnormal morphology and motility of the sperm. • In the female reproductive system, infertility may be caused by a range of abnormalities of the ovaries, uterus, fallopian tubes, and the endocrine system. 43
  • 44. • Infertility can be primary or secondary. • Primary infertility is when a pregnancy has never been achieved by a person, and secondary infertility is when at least one prior pregnancy has been achieved • Fertility care encompasses the prevention, diagnosis and treatment of infertility. • Equal and equitable access to fertility care remains a challenge in most countries; particularly in low and middle-income countries. • Fertility care is rarely prioritized in national universal health coverage benefit packages. 44
  • 45. Risk factors • Age. The quality and quantity of a woman's eggs begin to decline with age. In the mid-30s, the rate of follicle loss speeds, resulting in fewer and poorer quality eggs. This makes conception more difficult, and increases the risk of miscarriage. • Smoking. Besides damaging your cervix and fallopian tubes, smoking increases your risk of miscarriage and ectopic pregnancy • Weight. Being overweight or significantly underweight may affect ovulation. • Sexual history. Sexually transmitted infections such as chlamydia and gonorrhea can damage the fallopian tubes. • Alcohol. Excess alcohol consumption can reduce fertility. 45
  • 46. Symptoms • A menstrual cycle that's too long (35 days or more), too short (less than 21 days), irregular or absent can mean that you're not ovulating. • There might be no other signs or symptoms. When to see a doctor • Up to age 35, most doctors recommend trying to get pregnant for at least a year before testing or treatment. • If you're between 35 and 40, discuss your concerns with your doctor after six months of trying. • If you're older than 40, your doctor might suggest testing or treatment 46
  • 47. FEMALE REPRODUCTIVE ORGAN FERTILIZATION AND IMPLANTATION 47
  • 48. What causes infertility? • Tubal disorders such as blocked fallopian tubes→ caused by untreated sexually transmitted infections (STIs) or complications of unsafe abortion, postpartum sepsis or abdominal/pelvic surgery; • Uterine disorders→ which could be inflammatory in nature (endometriosis), congenital in nature (septate uterus), or benign in nature (fibroids); • Disorders of the ovaries→ such as polycystic ovarian syndrome and other follicular disorders; • Disorders of the endocrine system→ pituitary cancers and hypopituitarism causing imbalances of reproductive hormones. • Environmental and lifestyle factors→ smoking, excessive alcohol intake, obesity. In addition, exposure to environmental pollutants and toxins can be directly toxic to gametes (eggs and sperm), resulting in their decreased numbers and poor quality, leading to infertility • In some cases, the cause of infertility is never found. A combination of several minor factors in both partners could cause unexplained fertility problems. 48
  • 49. Diagnosis of female infertility • Physical examination – including medical history • Blood tests – to check for the presence of ovulation hormones • Pap test • Laparoscopy – a ‘keyhole’ surgical procedure in which an instrument is inserted through a small incision in the abdomen so that the reproductive organs can be examined • Hysteroscopy: In this test, a device called a hysteroscope (a flexible, thin device with a camera) is inserted into the vagina and through the cervix. The healthcare provider moves it into the uterus to view the inside of the organ. • Ultrasound scans – to check for the presence of fibroids. 49
  • 50. Treatment for female infertility • Surgery • Ovulation induction (using hormone treatment) • Artificial insemination (IUI) • Assisted reproductive technologies (ART) including in-vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) 50
  • 51. Surgery for female infertility INDICATIONS • Fibroids – non-malignant tumours growing inside the uterus • Polyps – overgrowths of the uterine lining (endometrium) • Endometriosis – the growth of endometrial tissue outside the uterus, which can block the fallopian tubes • Abnormalities of the uterus – such as a uterine septum • Ovarian cysts – which can be drained or removed. 51
  • 52. Ovulation induction for female infertility • Used if a woman is not ovulating or not ovulating regularly. • It involves taking a hormone medication (tablets or injections) to stimulate ovulation. • The response to the hormones is monitored with ultrasound and when the time is right, an injection is given to trigger ovulation. • Timing intercourse to coincide with ovulation offers the chance of pregnancy. 52
  • 53. Artificial insemination or IUI • It involves insertion of the male partner’s (or a donor’s) sperm into a woman’s uterus at or just before the time of ovulation. • IUI can help couples with so called unexplained infertility or couples where the male partner has minor sperm abnormalities. • IUI can be performed during a natural menstrual cycle, or in combination with ovulation induction (OI) if the woman has irregular menstrual cycles. • If a pregnancy is not achieved after a few IUI attempts, IVF or intracytoplasmic sperm injection (ICSI) may be needed. 53
  • 54. In-vitro fertilization Assisted reproductive technologies (ART) includes in-vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), which is used when there is a male cause of infertility. ART involves hormone stimulation to make the ovaries produce 10 to 15 eggs rather than the one which normally matures every month. When the eggs are ‘ready’ they are retrieved in an ultrasound-guided procedure. In the case of IVF the collected eggs are then mixed with sperm from the male partner or a donor, and in the case of ICSI each egg is injected with a single sperm. Two to 5 days later an embryo is transferred to the woman’s uterus using a thin tube that is inserted through the cervix. If there are more embryos than needed, these can be frozen for future use. 54
  • 55. IVF success rates • Under 34: 44 per cent chance of a live birth • 35-39: 31 per cent chance of a live birth • 40-44: 11 per cent chance of a live birth • 44 and above: one per cent chance of a live birth. • (Research using the Australian and New Zealand Assisted Reproduction Database, calculated the chance of a woman having a baby from her first cycle of IVF according to her age) 55
  • 56. 56
  • 57. Donor conception is the process of having a baby using donated sperm, eggs or embryos through self-insemination or fertility treatment such as IVF. Sometimes it involves surrogacy, too. Donor conception involves a donor (the person donating sperm, eggs or an embryo) and recipient parent(s) who receive the donation. A child born as a result of the donation is known as a donor-conceived person. • There are many reasons why donor sperm, eggs or embryos may be needed.  Donor sperm: • a male partner does not produce any sperm or normal sperm • there is a high risk of a man passing on a genetic disease or abnormality to a child. • by single women and women in same-sex relationships. The process of donor insemination is the same as IUI. • If the woman also has an infertility problem, donor sperm can be used in IVF treatment.  Donor eggs • a woman doesn’t produce eggs or her eggs are of low quality. • a woman has experienced several miscarriages, or • there is a high risk of the woman passing on a genetic disease or abnormality to a child.  Donor embryos • Donor embryos can be used if a person or couple requires both donor sperm and donor eggs to achieve a pregnancy. Although rare, some people who have frozen embryos that they don’t need, choose to donate them for someone else to use. 57
  • 58. Surrogacy • Surrogacy involves a woman (the surrogate) carrying a child for another person or couple with the intention of giving the child to that person or couple after birth. • The supreme court’s final verdict announced on December 12, 2016, and holds that surrogacy is legal for infertile married couples but illegal for singles, transgender and foreign nationals. • It’s a popular option for male same-sex couples who want to have a family and also can be used by people who are single in other countries.  Traditional surrogacy • The surrogate provides her own egg, which is inseminated with the parent’s sperm. This can be done using (IVF) or artificial insemination. In this case, the baby is biologically related to the surrogate.  Gestational surrogacy • In this type of pregnancy, an embryo is transferred into the surrogate’s uterus. The embryo is formed from the egg and sperm of the intended parents or from donors, using IVF. 58
  • 59. Risks of assisted reproductive technologies 59 Ovarian hyperstimulation syndrome (OHSS) an increased incidence of multiple pregnancies an increased risk of premature labour and low birth weight an increased risk of caesarean delivery
  • 60. Global scenerio • This problem was able to draw the attention of government leaders and reproductive health experts in ICPD, 1994. This conference recommended all members countries to include infertility as part of their reproductive health care program. • 48 million couples and 186 million individuals live with infertility, half of these couples are living in Sub-Saharan Africa (SSA) and South Asia globally. (WHO) • 1 in 4 couples in developing countries is affected by infertility. (WHO, 2004) • The use of assisted reproductive technology (ART) by infertile couples is increasing by 5% to 10% per year. • Nearly 2% of live births in the U.S. are a result of assisted reproductive technology. (CDC, 2017) 60
  • 61. 61
  • 62. Causes of infertility amongst couples visited at infertility centre Kathmandu Nepal 62
  • 63. National Level Advocacy Workshop On Infertility: Causes And Consequences Of Violence Against Women • WOREC in support of Swiss Network for International Studies and Graduate Institute of International and Development studies Geneva conducted National Advocacy Workshop on Infertility: January 27, 2020. • The main objective of the workshop was to explore the perception of infertility, its causes and consequences and health-seeking behavior among women and their husbands in order to develop a strategy for action and policy setting. • Conclusions • Among all causes of infertility in the global south, it has been seen that 50 percent of the problem lies within men whereas 90 percent of burden is borne by the women. • Men are also victimized because of infertility and considered impotent (Napunsak). (a/c study in 2018) 63
  • 64. • Infertility is a pretext of polygamy in all ethnicity whereas the social stigma of infertility is high among Brahmin and Chettri. • Depression and suicidal attempts are high in infertile women so it is better not to ask any couple when are we going to hear good news? When I will get the chance to become an Aunt or Uncle and so on. • Infertility has various dimensions like bio-medical, social, science and technology. The issue of infertility should not be left alone with bio-medical treatment rather it should go clubbing with a social dimension too. • Safe Motherhood Act 2075, has also incorporated the issue of infertility as one of the reproductive morbidities 64
  • 65. 65
  • 66. Introduction • Menopause is the time that marks the end of menstrual cycles in women. It's diagnosed after you've gone 12 months without a menstrual period. • Most women experience menopause between the ages of 45 and 55 years as a natural part of biological ageing. • Some women experience menopause earlier (before 40 years of age). This ‘premature menopause’ may be because of certain chromosomal abnormalities, autoimmune disorders, or other unknown causes. • Menopause is caused by the loss of ovarian follicular function and a decline in circulating blood oestrogen levels. • Menopause can affect physical, emotional, mental and social well-being. • Menopause can also be induced as a consequence of surgical procedures that involve removal of both ovaries or medical interventions that cause cessation of ovarian function (for example radiation therapy or chemotherapy). 66
  • 67. Stages of menopause • Perimenopause: This is the transitional time that starts before menopause and includes the 12 months after person’s last period. • Menopause: This starts either after 12 months of the last period or when menstruation has stopped for a clinical reason, such as the removal of the ovaries. • Postmenopause: Postmeopause refers to the years after menopause, although it can be difficult to know when menopause finished and postmenopause starts. 67
  • 68. 68
  • 69. Complications After menopause, your risk of certain medical conditions increases. • Heart and blood vessel (cardiovascular) disease. When your estrogen levels decline, your risk of cardiovascular disease increases. For example, blood pressure, LDL and triglycerides tend to go up after menopause. (Nearly a third of women develop cardiovascular disease, the AHA says) • Osteoporosis. This condition causes bones to become brittle and weak, leading to an increased risk of fractures. Women are 4 times as likely as men to develop osteoporosis • Urinary incontinence. As the tissues of your vagina and urethra lose elasticity, you may experience frequent, sudden, strong urges to urinate, followed by an involuntary loss of urine (urge incontinence), or the loss of urine with coughing, laughing or lifting (stress incontinence). You may have urinary tract infections more often. • Weakening of the pelvic support structures. increasing the risk of pelvic organ prolapse due to Loss of bone • Sexual function. Vaginal dryness from decreased moisture production and loss of elasticity can cause discomfort and slight bleeding during sexual intercourse • Weight gain because metabolism slows. • Skin: The decrease in estrogen, as well as aging itself, causes a decrease in the amount of collagen (a protein that makes skin strong) and elastin (a protein that makes skin elastic). Thus, the skin may become thinner, drier, less elastic, and more vulnerable to injury. 69
  • 70. LGBTQIA+ and menopause • Menopause can affect anyone who is born with ovaries. • If a person starts taking supplementary testosterone as part of their transition, they may experience menopause symptoms when their ovaries stop producing eggs. • The symptoms of menopause will be the same as those of cisgender women. • It is essential that transgender people have access to healthcare providers who understand their needs and can address them effectively. 70
  • 71. Menopausal Health Status of Nepalese Women JNMA 2017 71
  • 73. References 1. https://www.msdmanuals.com/home/women-s-health- issues/family-planning/abortion 2. acog.org/advocacy/facts-are-important/abortion-is-healthcare 3. https://www.acog.org/clinical-information/policy-and-position- statements/statements-of-policy/2022/abortion-policy 4. https://www.who.int/news-room/fact-sheets/detail/abortion 5. https://reproductive-health- journal.biomedcentral.com/articles/10.1186/s12978-019-0755-0 6. https://en.wikipedia.org/wiki/Abortion 7. https://www.britannica.com/science/abortion-pregnancy 73
  • 74. 8. Raymond EG, Grimes DA (February 2012.. "The comparative safety of legal induced abortion and childbirth in the United States 9. Bearak J, Popinchalk A, Ganatra B, Moller A-B, Tunçalp Ö, Beavin C et al. Unintended pregnancy and abortion by income, region, and the legal status of abortion: estimates from a comprehensive model for 1990–2019. Lancet Glob Health. 2020 Sep; 8(9):e1152-e1161. doi: 10.1016/S2214-109X(20)30315-6 10. Ganatra B, Gerdts C, Rossier C, Johnson Jr B R, Tuncalp Ö, Assifi A et al. Global, regional, and subregional classification of abortions by safety, 2010–14: estimates from a Bayesian hierarchical model. The Lancet. 2017 Sep 11. Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014 Jun; 2(6):e323-33. 12. Singh S, Maddow-Zimet I. Facility-based treatment for medical complications resulting from unsafe pregnancy termination in the developing world, 2012: a review of evidence from 26 countries. BJOG 2015; published online Aug 19. DOI:10.1111/1471-0528.13552. 13. Vlassoff et al. Economic impact of unsafe abortion-related morbidity and mortality: evidence and estimation challenges. Brighton, Institute of Development Studies, 2008 (IDS Research Reports 59). 74
  • 75. 1. https://www.who.int/news-room/fact-sheets/detail/infertility 2. https://www.mayoclinic.org/diseases-conditions/female- infertility/symptoms-causes/syc-20354308 3. https://www.betterhealth.vic.gov.au/health/conditionsandtreat ments/infertility-in-women 4. https://www.singlecare.com/blog/news/infertility-statistics/ • https://www.mayoclinic.org/diseases- conditions/menopause/symptoms-causes/syc-20353397 • https://www.who.int/news-room/fact-sheets/detail/menopause • https://www.healthline.com/health/menopause#outlook 75
  • 76. 76

Editor's Notes

  1. Bullemia nervosa – self induced vomiting , abuse of laxatives, periods of starvation
  2. Prenatal care is the health care you get while you are pregnant. It includes your checkups and prenatal testing. Prenatal care can help keep you and your baby healthy. It lets your health care provider spot health problems early. Throughout life, heart attacks are twice as common in men than women.
  3. Cvd becomes undiagnosed and untreated in women.
  4. Incest is human sexual activity between family members or close relatives.
  5. Unsafe abortions—those performed by people lacking the necessary skills, or in inadequately resourced settings—are a major cause of maternal death, especially in the developing world, though self-managed medication abortions are highly effective and safe. 
  6. Methods Surgical abortion (surgical evacuation): Removal of the contents of the uterus through the cervix Medical abortion : Use of drugs to stimulate contractions of the uterus, which expel the contents of the uterus Ultrasonography is usually done to estimate the length of the pregnancy. In general, the more advanced the pregnancy, the greater the risk to the female of mortality or serious complications following an abortion.
  7. Dilatation and curettage with suction: A speculum is used in the vagina to enable the practitioner to see the cervix. A local anesthetic (such as lidocaine) is injected into the cervix to reduce discomfort, and the cervix is dilated. Then a flexible tube attached to a vacuum source is inserted into the uterus to remove the fetus and placenta. The vacuum source may be a handheld syringe or similar instrument or an electrical suction machine. Sometimes a small, sharp, scoop-shaped instrument (curet) is inserted to remove any remaining tissue. This procedure is done gently to reduce the risk of scarring and infertility. Dilation and evacuation After the cervix is dilated, suction and forceps are used to remove the fetus and placenta. A sharp curet may be used gently to make sure all products of conception have been removed.
  8. For an abortion during early pregnancy (less than 11 weeks), the abortion process can be completed at home. For an abortion later in pregnancy, the woman typically is admitted to the hospital to take the drugs that will induce labor. Drugs used to induce abortion include mifepristone (RU 486), followed by a prostaglandin, such as misoprostol.
  9. Around 73 million induced abortions take place worldwide each year.(WHO) Six out of 10 (61%) of all unintended pregnancies, and 3 out of 10 (29%) of all pregnancies, end in induced abortion(9).(WHO) Each year, 4.7–13.2% of maternal deaths can be attributed to unsafe abortion (11). In developed regions, it is estimated that 30 women die for every 100 000 unsafe abortions. In developing regions, that number rises to 220 deaths per 100 000 unsafe abortions (10). Estimates from 2012 indicate that in developing countries alone, 7 million women per year were treated in hospital facilities for complications of unsafe abortion (12). Developing countries bear the burden of 97% of all unsafe abortions. More than half of all unsafe abortions occur in Asia, most of them in south and central Asia. In Latin American and Africa, the majority (approximately 3 out of 4) of all abortions are unsafe.(10)
  10. A total of 79,952 women have received safe abortion service in FY 2077/78. The figures were 87,869 in FY 2076/77; 95,746 in FY 2075/76 and 98,640 in 2074/75 showing the decreasing trend over the years. utilization of abortion services is also in decreasing trend. This data need to be cautiously interpreted as the adolescents prefer to utilize the sexual and reproductive health (SRH) services from the private sector due to several reasons -The post abortion contraception service has increased from 72.7% in 2076/77 to 76.7% in FY 2077/78. The acceptance of Short Acting Reversible Contraceptive (SARC) is higher (61.98%) in comparison to long-acting reversible contraceptive and permanent method (LARCPM) (14.72%) Among the total safe abortion service, 57350 were medical abortion which is around 72% of the total safe abortion service were received whereas remaining 22602 were surgical abortion which is around 28% of the total safe abortion Listing of the safe abortion service sites and service providers has started at all seven province and the local level aligning with the safe abortion service management guideline 2021.(DOHS)
  11. Medical abortion is around 72% whereas surgical abortion is around 28% of the total safe abortion service received.
  12. Province 4 (15%) has the highest proportion of pregnancies ending in abortion, while Province 2 has the lowest (5%).
  13. Prior to 2002, Nepal had strict anti-abortion laws which ensured not only the imprisonment of the pregnant women who seek abortion but also their family members. In fact about 20% of women prisoners were imprisoned for abortion-related choices
  14. Nepal legalized abortion in March 2002 in response to advocacy efforts that emphasized the high rates of maternal morbidity and mortality attributed to unsafe abortions. During the initial implementation of safe abortion services in 2004, however, only physicians were trained in safe abortion practices. Family planning literature from several other countries provided data on the safety and efficacy of shifting abortion care to mid-level providers.  In response, Nepal decentralized services by training nurses and auxiliary nurse midwives as providers. Since 2008, mid-level providers have been authorized to provide manual vacuum aspiration up to eight weeks’ gestation. Auxiliary nurse midwives have been providing medical abortions since 2009
  15. Family welfare division
  16. Complications- rare (trained health care practitioner in a hospital or clinic. Serious complications occur in fewer than 1% of women who have an abortion. Death after an abortion is very rare. About 6 out of a million women who have an abortion die, compared with about 140 out of a million women who deliver a full-term baby. The risk of complications is related to the method used. Surgical evacuation: Complications are rare when surgical abortions are done by trained practitioners. The uterus is torn (perforated) by a surgical instrument in fewer than 1 of 1,000 abortions. Injury of the intestine or another organ is even rarer. Severe bleeding during or immediately after the procedure occurs in 6 of 10,000 abortions. Very rarely, the procedure or a subsequent infection causes scar tissue to form in the lining of the uterus, resulting in sterility. This disorder is called Asherman syndrome. Drugs: Mifepristone and the prostaglandin misoprostol have side effects. The most common are crampy pelvic pain, vaginal bleeding, and gastrointestinal problems such as nausea, vomiting, and diarrhea. Either method: Bleeding and infection can occur if part of the placenta is left in the uterus. Later, particularly if the woman is inactive, blood clots may develop in the legs. If the fetus has Rh-positive blood, a woman who has Rh-negative blood may produce Rh antibodies—as in any pregnancy, miscarriage, or delivery. Such antibodies may endanger subsequent pregnancies. Giving the woman injections of Rho(D) immune globulin prevents antibodies from developing. Immune globulin may be optional for pregnancies lasting less than 8 weeks. Psychologic problems after an abortion are more likely if the following are present Psychologic symptoms before pregnancy Limited social support or a sense of disapproval in their support system
  17. Infertility results from female factors about one-third of the time and both female and male factors about one-third of the time. The cause is either unknown or a combination of male and female factors in the remaining cases.
  18. Getting to a healthy body mass index (BMI) might increase the frequency of ovulation and likelihood of pregnancy
  19. Steps in human reproduction One of the two ovaries releases a mature egg. The egg is picked up by the fallopian tube. Sperm swim up the cervix, through the uterus and into the fallopian tube to reach the egg for fertilization. The fertilized egg travels down the fallopian tube to the uterus. The fertilized egg attaches (implants) to the inside of the uterus and grows
  20.  it is sometimes not possible to explain the causes of infertility. The relative importance of these causes of female infertility may differ from country to country, fibroids – non-malignant tumours inside the womb polyps – overgrowths of the endometrium, which can be prompted by the presence of fibroids Endometriosis is a condition in which cells from the lining of the uterus (the endometrium) migrate to other parts of the pelvis. It can damage the fallopian tubes and the ovaries, and affect the movement of the egg and sperm
  21. Oral medications such as clomiphene citrate (Clomid, Serophene) can dull the response of receptors in the brain to naturally occurring oestrogens in the body. This leads to an increase in the release of hormones from the brain which stimulate ovulation.
  22. the world’s first baby was born through in-vitro fertilisation (IVF) in the UK in 1978, The key difference between IVF and ICSI is how the sperm fertilizes the egg. In IVF, the egg and sperm (of which there are many) are left in a laboratory dish to fertilize on their own. In ICSI, the selected sperm is directly injected into the egg. ICSI yields satisfactory fertilization results and helps reduce problems with abnormal fertilization caused by eggs and sperm – such as fertilization by multiple sperm and the inability of the sperm to penetrate the eggs and fertilize, etc. For those with significant sperm problems, such as with high sperm DNA fragmentation, with a history of previous fertilization failure or with poor embryo quality, then IMSI (Intracytoplasmic Morphologically Selected Sperm Injection) may be advised by the physician. IMSI is a technique using a high-powered microscope to select sperm with the best morphology and the lowest amount of fragmentation to fertilize with eggs. IVF is used for female infertility and unexplained infertility, and ICSI is used when there is a male cause of infertility.
  23. The chance of a live birth following IVF depends on many factors including the woman’s age, the man’s age and the cause of infertility.
  24. Surrogacy gives people an opportunity to have a child if they can’t be pregnant themselves. Altruistic Surrogacy: women agree to hold the baby in their womb for social service Commercial Surrogacy: is done for commercial benefit and it has been banned in most countries. Law Relating to Surrogacy in Nepal Supreme Court  gave a directive order to the concerned authority to make an appropriate law to regulate surrogacy in Nepal considering the following fact (December 12, 2016) Completely ban commercial surrogacy since a mother’s womb can never be commercialized. If a Nepali married couple has been certified by a medical board that they are incapable of producing children because of infertility or other health conditions, they should be allowed. Same-sex couples or single men and women shall not be allowed to practice surrogacy Foreigners are not to be allowed to practice surrogacy in Nepal The mutual consent of the intended married couple and surrogate is required Only for altruistic and non-commercial purposes Criteria for surrogate mother Service to be provided by health institutions that fulfill criteria as prescribed by the law upon taking consent of the such authority Both the intended couple or surrogate has to apply to the concerned authority first Determination of legal rights and duties of legal parents Determination of rights and duties of surrogate mother Clarity on registration of birth and other events Provision of institutions for supervision, monitoring, and inspection of whether laws have complied with or not
  25. Addressing challenges Availability, access, and quality of interventions to address infertility remain a challenge in most countries. Moreover, a lack of trained personnel and the necessary equipment and infrastructure, and the currently high costs of treatment medicines, are major barriers even for countries that are actively addressing the needs of people with infertility. While assisted reproduction technologies (ART) have been available for more than three decades, with more than 5 million children born worldwide from ART interventions such as in vitro fertilization (IVF), these technologies are still largely unavailable, inaccessible and unaffordable in many parts of the world, particularly in low and middle-income countries (LMIC).  Government policies could mitigate the many inequities in access to safe and effective fertility care. Incorporating fertility awareness in national comprehensive sexuality education programmes, promoting healthy lifestyles to reduce behavioural risks, including prevention, diagnosis and early treatment of STIs, preventing complications of unsafe abortion, postpartum sepsis and abdominal/pelvic surgery, and addressing environmental toxins associated with infertility, are policy and programmatic interventions that all governments can implement. In addition, enabling laws and policies that regulate third party reproduction and ART are essential to ensure universal access without discrimination and to protect and promote the human rights of all parties involved. Once fertility policies are in place, it is essential to ensure that their implementation is monitored, and the quality of services is continually improved.
  26. Women rehabilitation centre.. Can female infertility be prevented? -Most forms of female infertility cannot be predicted or prevented. -However, the risk factors that may contribute to infertility can, in some cases, be controlled to prevent this condition. -For example, lifestyle modifications, such as reducing alcohol consumption and quitting smoking, maintaining a healthy weight and developing good exercise habits. -It’s important to regularly visit your healthcare provider and discuss any other risks you may have for female infertility. Why addressing infertility is important? -Addressing infertility is therefore an important part of realizing the right of individuals and couples to find a family. -A wide variety of people, including heterosexual couples, same-sex partners, older persons, individuals who are not in sexual relationships and those with certain medical conditions, such as some HIV sero-discordant couples and cancer survivors, may require infertility management and fertility care services. -Infertility has significant negative social impacts on the lives of infertile couples and particularly women, who frequently experience violence, divorce, social stigma, emotional stress, depression, anxiety and low self-esteem.  -In some settings, fear of infertility can deter women and men from using contraception.  In such situations, education and awareness-raising interventions to address understanding of the prevalence and determinants of fertility and infertility is essential.
  27. Brain fog-confusion, forgetfulness, lack of focus and mental clarity. The symptoms experienced during and following the menopausal transition vary substantially from person to person. Some have few if any symptoms. For others, symptoms can be severe and affect daily activities and quality of life. Some can experience symptoms for several years. Irregular periods Vaginal dryness, pain during intercourse and incontinence Hot flashes (Hot flashes refer to a sudden feeling of heat in the face, neck and chest, often accompanied by flushing of the skin, perspiration (sweating), palpitations, and acute feelings of physical discomfort which can last several minutes) Chills Night sweats Sleep problems Mood changes, depression or anxiety Weight gain and slowed metabolism Thinning hair and dry skin Loss of breast fullness Skipping periods during perimenopause is common and expected. Often, menstrual periods will skip a month and return, or skip several months and then start monthly cycles again for a few months. Periods also tend to happen on shorter cycles. Despite irregular periods, pregnancy is possible
  28. Strengthening pelvic floor muscles with Kegel exercises and using a topical vaginal estrogen may help relieve symptoms of incontinence. Hormone therapy may also be an effective treatment option for menopausal urinary tract and vaginal changes that can result in urinary incontinence.
  29. LGBTQIA+: An acronym used to signify Gay, Lesbian, Bisexual, Transgender, Queer, Intersex, and Asexual people collectively.  Lesbian: A woman who has a significant attraction, primarily to members of the same gender, or who identifies as a member of the lesbian community. Gay: One who has significant sexual attractions primarily to members of the same gender or sex, or who identifies as a member of the gay community. Typically associated with men. Bisexual: The potential to be sexually attracted to people of more than one sex and/or gender, not necessarily at the same time, not necessarily in the same way, and not necessarily to the same degree. Transgender: Umbrella term for those whose gender expression or identity is not congruent with the sex assigned at birth and/or whose gender is not validated by the dominant culture.  Queer: Reclaimed derogatory slang by many who reject gender and sexual binaries. Also used as a political identity by many who want to dismantle oppressive systems in society.   Intersex: A general term used for a variety of bodies in which a person is born with reproductive or sexual anatomy that does not fit into the sex binary. Asexual: Umbrella term for those to tend not to have a sexual desire towards others; asexuals may experience romantic attractions and engage in sexual behavior. Non-Binary: “Non-binary” is generally used as an umbrella for various gender nonconforming identities, and is most often used by those who do not strictly identify as "male" and "female."  Pansexual: One who can feel an attraction to anyone, including individuals who do not identify as a specific gender. Pansexual people may describe their attraction as focusing on personality rather than gender. Cisgender: Umbrella term for those whose gender expression and gender identity are congruent with the sex assigned to them at birth, and whose gender is validated by the dominant culture.  Biological Sex: Category assigned to each of us at birth based on a variety of physical and biological characteristics, usually determined by genitals. Gender Identity: The internal perception of one’s gender, and how they label themselves, based on how much they align or don’t align with what they understand their options for gender to be. Common identity labels include man, woman, genderqueer, trans and more. Gender identity is sometimes confused with biological sex, or sex assigned at birth. Sexual Identity: The way in which one understands oneself in regard to one's sexuality. Ally: Someone that aligns with and supports a cause with another individual or group of people. A straight ally, more specifically, is an individual outside of the LGBTQIA+ community that supports their fight for equality and rights. Heterosexual Privilege: The benefits and access to resources one receives from society by virtue of being heterosexual and/or by virtue of being perceived to be heterosexual. Heterosexism or Heteronormativity: The presumption that heterosexuality is superior to all other sexual orientations. The oppression, discrimination, and bias against people who are not heterosexual.
  30. The importance of understanding menopause Menopause is often not discussed within families, communities, workplaces, or health-care settings. Women may not know that symptoms they experience are related to menopause, or that there are counselling and treatment options that can help alleviate discomfort. A woman’s health status entering the perimenopausal period will largely be determined by prior health and reproductive history, lifestyle and environmental factors. Therefore, perimenopausal care plays an important role in the promotion of healthy ageing and quality of life. Menopause can be an important transition from a social perspective, as well as a biological one. Socially, a women’s experience of menopause may be influenced by gender norms, familial and sociocultural factors, including how female ageing and the menopausal transition are viewed in her culture. The global population of postmenopausal women is growing. In 2021, women aged 50 and over accounted for 26% of all women and girls globally. This was up from 22% 10 years earlier
  31. You may need treatment if your symptoms are severe or affecting your quality of life Hormone therapy: women under the age of 60, or within 10 years of menopause onset, for the reduction or management of: hot flashes night sweats flushing vaginal atrophy osteoporosis Symptomatic treatment: medications for hair loss and vaginal dryness. Home remedies and lifestyle changes Keeping cool and staying comfortable Exercising and managing your weight Communicating your needs. Talk to a therapist or psychologist or family members about any feelings of depression, anxiety, sadness, isolation, insomnia, and identity changes.. Supplementing your diet. calcium, vitamin D, and magnesium  Practicing relaxation techniques 6Yoga or meditation Taking care of your skin. Apply moisturizers daily, avoid excessive bathing or swimming, which can dry out or irritate your skin. Quitting smoking and limiting alcohol use. Exposure to cigarettes, alcohols may make your symptoms worse Supplementing your diet.. Take calcium, vitamin D, and magnesium supplements to help reduce your risk for osteoporosis and improve energy levels and sleep.