2. Cutting Balloon
• Flextome cutting balloon
• Made up of 3 (2-3.25mm) to 4 (3.5-4mm)
microsurgical blades mounded longitudinally
on a non-compliant nylon balloon.
• Size – Diameter- 2.0 to 4.0mm with 0.25mm
increment.
Length- 6, 10 & 15mm
3. • Mechanism- longitudinal incision in the
plaque that allows controlled dilatation at
lower pressure with less vessel wall injury
4.
5.
6. Scoring Balloon
• AngioSculpt scoring balloon
• Consist of 3 rectangular spiral nitinol scoring
elements wrapped on a semi-compliant nylon
balloon
• Size – Diameter- 2.0 to 5.0mm
Length- 10, 15 & 20mm
Inflating pressure – wide 2 to 18 atm
7. • Mechanism- During dilatation, rectangular
scoring elements lock the device in place &
prevent watermelon seeding.
Dilatation force is concentrated over a small area
of the scoring elements & exert a force equal to
15-25 times that of conventional balloon leading
to large lumen expansion with limited vessel
wall injury.
• Advantage
– Smaller crossing profile (2.7Fr)
– Enhanced flexibility facilitates delivery of catheter
in tortuous anatomies.
9. - Late aneurysm
- Reported in perforation managed with prolonged
balloon inflation.
- Device entrapments
- During t/t of ISR, when wire passes through an
unopposed stent strut
10. • Various maneuvers to remove the entrapped
device:-
– Advancing the device forward & rotating it to
unhook the trapped strut or atherotome.
– Inflating second balloon alongside the entrapped
device
– Deep seating of the guiding catheter & controlled
retraction of the device.
– Surgical removal, if all unsuccessful
13. Mechanism-
• Differential cutting- rapidly rotating burr
selectively ablates rigid inelastic tissue
components (calcium & fibrous tissue) while the
elastic normal vessel wall components deflect
away from cutting edge
• Orthogonal displacement of friction- high speed
rotation changes the longitudinal friction vector
b/w the wire & burr to circumferential direction
which facilitates burr advancements through
tortuous anatomies
• Generated particle size- 5 micron, cleared by
reticuloendothelial system.
14. Indications for Use
• Calcified Vessels
• Failure to Dilate
• In-stent restenosis
– Multiple stent layers
– Jailed branches
• Ostial lesions (aorto-ostial lesions)
• Bifurcation lesions
• Long lesion <25mm
Rotational Atherectomy
15. Rotational Athectomy
• Occlusions not passable with guide wire
• Last remaining vessel
• Severe LV dysfunction
• Saphenous vein grafts
• Angiographic thrombus pre-treatment
• Significant dissection at treatment site
Contraindications
16. Precaution
• EF<30%
• Angulated lesions (≥45°)
• TPI- lesion of RCA, Dominant LCX, Proximal
LAD
• Should only be carried out in hospital where
emergency CABG is available.
17. Complication
1) Slow flow/ no reflow
0.5-2%
cause:-
• Large burr & higher speed
• Lesion that are thrombotic/ contain large amount of fatty atheroma
• Shorter time intervals b/w ablation runs
Prevention
-Slow speed rotational ablation (RPM 140,000-160,000)
-Minimal deceleration during ablation runs
-Multiple short runs of 30 seconds or less
-Rest period b/w runs
T/t-
-retraction of burr
-Optimization of perfusion pressure
-I/C vasodilators- NTG, CCB, adenosine, nicorandil
-IABP
18. 2) Perforation
- 0.05-1%
-Oversized burr
-Angulated lesions.
3) Burr entrapment
Burr crossing the lesion without adequate ablation.
T/T
-Gentle controlled traction with guide catheter
deep intubation or mother & child catheter
-Balloon inflation besides the burr
-Snare assisted traction
-Surgical removal
19. 4) Bradycardia/ AV block
RCA/ dominant LCX/ Proximal LAD
Large burr>2.25mm
Mechanism-
- microparticle interfering with vessels perfusing
AV node
-vibrations/ heat of burr causing reflex
bradycardia.
Prevention
- limiting ablation time <15-20seconds
-pretreatment with atropine
-Deactivate burr when slowing of heart rate is
noted
- asking the patient to cough.
20. Orbital atherectomy
• Diamond back 360° coronary orbital
atherectomy system.
• Ablating component- diamond encrusted
crown.
• Mechanism- differential sanding & centrifugal
force
21. Orbital atherectomy Rotational atherectomy
Eccentric crown orbits over guide wire at
two different speeds (80,000 & 120,000)
Single speeds
Selectively ablates rigid plaque
components while elastic tissue flexes
away from the crown.
- same-
Crown has diamonds chip both front &
back that enables ablation in both
antegrade & retrograde direction & hence
decrease risk of crown entrapment
Burr has diamond chip only distal, not
proximal, hence risk of crown entrapment
Paticle size generated is 2 micron & hence
less risk of slow/ no reflow
5 micron, more risk of slow/ noflow
Orbital motion allows continous flow of
blood, saline & debris which reduces the
potential ischemia, heat generation &
consequent thermal injury & restenosis.
22. • In one study, orbital atherectomy was a/w
deeper dissections, improved stent expansion
& lower incidence of stent strut
malapposition.
24. • Mechanism- XeCl emit light rays in UV
spectrum.
• Causes tissue removal by photoablation.
• Photoablation occur in 3 stages:-
– Photochemical- UV light absorb by tissue & cause
breakdown of carbon-carbon molecular bands
– Photothermal- high frequency molecular vibration
result in cellular breakdown & formation of vapor
bubbles
– Photomechanical- vapor bubbles expand & implode to
cause further tissue distruption