The document discusses RNA-based therapeutics as a promising treatment option for chronic diseases. It summarizes that RNA-based therapies work using RNA interference technology or antisense technology to target specific genes. The market is segmented by technology, application, end-users and geography, with RNA interference technology currently dominating. While in the clinical research phase, RNA-based therapeutics show potential for diseases that are difficult to treat using existing options.

1. RNA based therapeutics can
relief you from Chronic
disease!
Published Date: 9September 2014

2. Introduction to RNA based therapeutics Market
RNA based therapeutics has garnered significant attention in the recent years due to its
potential to treat variety of chronic diseases such as cancer, diabetes, AIDS, Tuberculosis and
certain cardiovascular conditions. Despite being in the clinical research phase, the RNA based
therapeutics is been explored as a promising treatment option for the diseases which are
difficult to treat. Development of this therapeutics is based on promising technologies such as
RNA interference technology (RNAi), antisense technology and SMaRT technology.
RNAi technology and antisense technology together are gaining prominence in the research
industry, as these technologies provide base sequence to develop RNA drugs. RNAi technology
works by causing destruction of specific mRNA molecules; whereas, antisense technology
works by synthesizing strand of RNA from known gene sequence.

3. Introduction to RNA based therapeutics Market
RNA based therapeutics market is segmented into technology, application, end-users and
geography. Technology segment is further categorized as enabling technologies and enabled
technologies. The segment of enabling technologies comprises of Microarrays, Labeling,
Purification, Linear amplification, qRT-PCR and Inhibition; whereas, enabled technologies
includes RNA interference technology (RNAi) and RNA antisense technology.
Enabled technologies account for largest market share due to their potential use in
therapeutics. The market for RNA based therapeutics is dominated by RNA interference
technology as numerous companies have exhibited their interest to develop the RNA drugs
using RNAi technology.
RNA based therapeutics have wide applications covering variety of chronic conditions such as
Cardiovascular, Kidney Diseases, Oncology, Infectious diseases, Metabolic disorders and
Others. The pipeline research is concentrated towards oncology and infectious diseases due
to their high prevalence and failure of existing treatment to effectively treat these conditions.
The end user market is segmented into research, therapeutics and diagnostics. Currently,
research and diagnostics segments are largely exploring the RNA technologies and therapies
for the commercialization of RNA drugs.

4. Introduction
Scope of the Report Key Benefits Key Audiences

5. KEY BENEFITS
An in-depth analysis of research and clinical developments
within RNA based therapeutics market is provided and light is
shed on market dynamics that would prove crucial in
understanding the market
Quantitative analysis of the current market and estimations
through 2013-2020 would assist strategists to design business
strategies to capitalize on the prevailing opportunities in the
market
Competitive structure of RNA based therapeutics market is
analyzed through Porter’s Five Forces model and provides in-depth
understanding of the influencing factors for
commercialization of RNA therapeutics
Detailed study of the strategies of key leaders, partnerships,
acquisitions and clinical trials in the RNA based therapeutics
market would be informative for professionals in the corporate
sector
Pin-point analysis of geographic segments would assist in
identification of most profitable segments to capitalize on

6. Table of Contents
1. INTRODUCTION
2. EXECUTIVE SUMMARY
3. MARKET OVERVIEW
4. GLOBAL RNA BASED THERAPEUTICS MARKET BY TECHNOLOGIES, 2013-
2020, $MILLION
5. GLOBAL RNA BASED THERAPEUTICS MARKET BY APPLICATIONS, 2013-
2020, $MILLION
6. GLOBAL RNA BASED THERAPEUTICS MARKET BY END USERS, 2013-2020,
$MILLION
7. GLOBAL RNA BASED THERAPEUTICS MARKET BY GEOGRAPHY, 2013-2020,
$MILLION
8. COMPANY PROFILES

7. RNA based therapeutics Market Overview
Market
Definition
and Scope
Historical
perspective &
current market
RNA
Based
trends
Therapeutics
Market
Overview
Conventional
Vs RNA-based
therapeutics
Addressable
Market
Analysis
Key Findings
Market
Dynamics
Clinical
Trials For
RNA Based
Therapeutics
Pipeline Review

8. MARKET DYNAMICS
Market Dynamics
Key
Market
Drivers
Hurdles in drug
delivery
Key
Market
Restraint
Key
Market
Drivers
s
Target
specificty &
selectivity of
treatment
Strategic
Alliances
and Funding
More intense
product
focus against
platform
technology
High cost of
research and threat
of failure.
Promising
technologies
driving the
RNA based
therapeutics

9. Global RNA Based Therapeutics by End - User
Research
RNA
Based
Therapeutics
Market by
End User
Therapeuti
Diagnosis cs

10. Global RNA Based Therapeutics Market BY
Applications
RNA Based
Therapeutics
Market by
Applications
Cardiovascular
Manufacturing Industry
Kidney Diseases
Oncology
Infectious diseases
Metabolic disorders
Healthcare Industry

11. Company Profiles
1. Quark Pharmaceuticals, Inc. (USA)
2. Alnylam Pharmaceuticals, Inc. (USA)
3. Dicerna Pharmaceuticals, Inc. (USA)
4. Tekmira Pharmaceuticals Corp. (Canada)
5. Benitec Biopharma Limited (Australia)
6. Cenix BioScience GmbH (Germany)
7. Genzyme Corporation (USA) (A Sanofi Company)
8. Silence Therapeutics PLC (UK)
9. Sirnaomics, Inc. (USA)

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