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Alessandra Dall’Agnese  English for Science and Technology Thursday, 11 th  November, 2010 1. What is an axolotl ( Ambystoma mexicanum) ? 2. Why is it important to study axolotls?  3. Basics of limb regeneration. 4. Applicability to humans of limb regeneration studies. Axolotl Limb Regeneration
1 What is an axolotl (A. mexicanum)? ,[object Object],[object Object],( http://www.axolotl.org ) 2 Why is it important to study axolotls? ,[object Object],[object Object],(Gardiner, 2005) LIMB
[object Object],[object Object],[object Object],3) Basics of limb regeneration (Gardiner, 2005)
3) Basics of limb regeneration AMPUTATION 1) WOUND HEALING AND DEDIFFERENTIATION  2) BLASTEMA FORMATION 3) RE-DEVELOPMENT The regenerate =  the amputated part! Pictures from Limb Regeneration Movie. Produced by HHMI in collaboration with Prof. David Gardiner.
[object Object],[object Object],Why no regeneration at other sites?  Why no regeneration at other sites?  4) Applicability to humans Picture from Regenerated Body Parts Video – CBS News Axolotls – regenerative animals Limb regeneration T urn on limb regenerative program in humans
[object Object],[object Object],[object Object],[object Object],[object Object],References

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Axolotl regeneration

  • 1. Alessandra Dall’Agnese English for Science and Technology Thursday, 11 th November, 2010 1. What is an axolotl ( Ambystoma mexicanum) ? 2. Why is it important to study axolotls? 3. Basics of limb regeneration. 4. Applicability to humans of limb regeneration studies. Axolotl Limb Regeneration
  • 2.
  • 3.
  • 4. 3) Basics of limb regeneration AMPUTATION 1) WOUND HEALING AND DEDIFFERENTIATION 2) BLASTEMA FORMATION 3) RE-DEVELOPMENT The regenerate = the amputated part! Pictures from Limb Regeneration Movie. Produced by HHMI in collaboration with Prof. David Gardiner.
  • 5.
  • 6.