7. www.aleidavillaespinosa.com
However, its importance in sheep and goats is still unclear. Increasing evidence suggests a role in these species,
although, scarce serological studies have been made in small ruminants in reproductive problems. The present work
shows an important seroprevalence of N. caninum in cases of abortion in sheep and goats in Spain. However, the
presence of antibodies does not necessary prove that the infection caused the abortion. The high title of antibodies in
some animals might suggest a relationship with the abortion.
8. www.aleidavillaespinosa.com
seroprevalence depends on cutoff values of the serologic tests, and it seems that in all cases they are presumptive as
none has been validated based on the recovery of the viable parasite in any host. In our case cutoff value was used
according to the manufactured and has shown that nine negative samples were very close to it, suggesting that
seroprevalence might vary, probably being increased.
9. www.aleidavillaespinosa.com
The immune system of the fetus becomes increasingly competent as gestation progresses. During the first trimester of
pregnancy the fetus is vulnerable to infection and can only mount primitive immune responses.
Infection occurring earlier in gestation is more likely to have severe consequences to the fetus.
Serological studies may contribute to the understanding of the disease in small ruminants.
10. www.aleidavillaespinosa.com
The immune system of the fetus becomes increasingly competent as gestation progresses. During the first trimester of
pregnancy the fetus is vulnerable to infection and can only mount primitive immune responses.
Infection occurring earlier in gestation is more likely to have severe consequences to the fetus.
Serological studies may contribute to the understanding of the disease in small ruminants.