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1. What are the roles of micromeres during sea urchin development? How is this lineage specified,
where are the cells found during embryogenesis, and what are some of the molecular
mechanisms underlying their commitment to terminal differentiation? Provide experimental
support. 2. Describe the gene regulatory network that specifies the large micromeres. What
maternal inputs are required? What zygotic gene is critical for suppressing micromere specification
in all other cells?

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