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Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
TELMISARTAN
HYDROCHLOROTHIAZIDE
TABLETS
80 MG/12.5 MG
Package leaflet: Information for the
patient
Telmisartan/ Hydrochlorothiazide
80mg/12.5mg Tablets.
Read all of this leaflet carefully before you
start taking this medicine because it
contains important information for you.
- Keep this leaflet. You may need to read it
again.
- If you have any further questions, ask your
doctor or pharmacist.
- This medicine has been prescribed for you
only. Do not pass it on to others. It may
harm them, even if their signs of illness are
the same as yours.
- If any of the side effects gets serious, or if
you notice any side effects not listed in this
leaflet, please tell your doctor.
What is in this leaflet
1. What Telmisartan HCT is and what it is
used for
2. Before you are given Telmisartan HCT
3. How you will be given Telmisartan HCT
4. Possible side effects
5. How Telmisartan HCT is stored
6. Further Information
1. What Telmisartan HCT is and what
it is used for
Telmisartan HCT is a combination of two
active substances, telmisartan and
hydrochlorothiazide in one tablet. Both of
these substances help to control high blood
pressure.
- Telmisartan belongs to a group of
medicines called angiotensin II receptor
antagonists. Angiotensin-II is a substance
produced in your body which causes your
blood vessels to narrow thus increasing your
blood pressure. Telmisartan blocks the
effect of angiotensin II so that the blood
vessels relax, and your blood pressure is
lowered.
- Hydrochlorothiazide belongs to a group of
medicines called thiazide diuretics, which
cause your urine output to increase, leading
to a lowering of your blood pressure.
High blood pressure, if not treated, can
damage blood vessels in several organs,
which could lead sometimes to heart attack,
heart or kidney failure, stroke, or blindness.
There are usually no symptoms of high
blood pressure before damage occurs. Thus
it is important to regularly measure blood
pressure to verify if it is within the normal
range. Telmisartan HCT 80 mg/12.5 mg or
in patients who have been previously
stabilised by telmisartan and
hydrochlorothiazide given separately.
2. Before you are given Telmisartan
HCT
Do not take Telmisartan HCT :
- if you are allergic to telmisartan or any
other ingredients of this medicine (listed in
section 6).
- if you are allergic to hydrochlorothiazide or
to any other sulfonamide-derived
medicines.
- if you are more than 3 months pregnant. (It
is also better to avoid Telmisartan HCT in
early pregnancy-see pregnancy section.)
- if you have severe liver problems such as
cholestasis or biliary obstruction (problems
with drainage of the bile from liver and the
gall bladder) or any other severe liver
disease.
- if you have severe kidney disease.
- if your doctor determines that you have
low potassium levels or high calcium levels
in your blood that do not get better with
treatment.
- if you have diabetes or impaired kidney
function and you are treated with a blood
pressure lowering medicine containing
aliskiren.
If any of the above applies to you, tell your
doctor or pharmacist before taking
Telmisartan HCT .
Warnings and precautions
Talk to your doctor before taking this
medicine if you are suffering or have ever
suffered from any of the following
conditions or illnesses:
- Low blood pressure (hypotension), likely to
occur if you are dehydrated (excessive loss
of body water) or have salt deficiency due to
diuretic therapy (water tablets), low-salt
diet, diarrhoea, vomiting, or haemodialysis.
- Kidney disease or kidney transplant.
- Renal artery stenosis (narrowing of the
blood vessels to one or both kidneys).
- Liver disease.
- Heart trouble.
- Diabetes.
- Gout.
Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
- Raised aldosterone levels (water and salt
retention in the body along with imbalance
of various blood minerals).
- Systemic lupus erythematosus (also called
“lupus” or “SLE”) a disease where the body’s
immune system attacks the body.
- The active ingredient hydrochlorothiazide
can cause an unusual reaction, resulting in a
decrease in vision and eye pain. These could
be symptoms of an increase of pressure in
your eye and can happen within hours to
weeks of taking Telmisartan HCT. This can
lead to permanent vision impairment, if not
treated.
Talk to your doctor before taking
Telmisartan HCT :
-
- if you are taking any of the following
medicines used to treat high blood
pressure:
o an ACE-inhibitor (for example enalapril,
lisinopril, ramipril), in particular if you have
diabetes-related kidney problems.
o aliskiren.
- Your doctor may check your kidney
function, blood pressure, and the amount of
electrolytes (e.g. potassium) in your blood at
regular intervals. See also information under
the heading “Do not take Telmisartan HCT”.
- if you are taking digoxin.
- if you have had skin cancer or if you
develop an unexpected skin lesion during
the treatment. Treatment with
hydrochlorothiazide, particularly long term
use with high doses, may increase the risk of
some types of skin and lip cancer (non-
melanoma skin cancer). Protect your skin
from sun exposure and UV rays while taking
Telmisartan HCT
You must tell your doctor if you think you
are (or might become) pregnant.
Telmisartan HCT is not recommended in
early pregnancy, and must not be taken if
you are more than 3 months pregnant, as it
may cause serious harm to your baby if used
at that stage (see pregnancy section).
Treatment with hydrochlorothiazide may
cause electrolyte imbalance in your body.
Typical symptoms of fluid or electrolyte
imbalance include dry mouth, weakness,
lethargy, drowsiness, restlessness, muscle
pain or cramps, nausea (feeling sick),
vomiting, tired muscles, and an abnormally
fast heart rate (faster than 100 beats per
minute). If you experience any of these you
should tell your doctor.
You should also tell your doctor, if you
experience an increased sensitivity of the
skin to the sun with symptoms of sunburn
(such as redness, itching, swelling,
blistering) occurring more quickly than
normal.
In case of surgery or anaesthetics, you
should tell your doctor that you are taking
Telmisartan HCT .
Telmisartan HCT may be less effective in
lowering the blood pressure in black
patients.
Children and adolescents
The use of Telmisartan HCT in children and
adolescents up to the age of 18 years is not
recommended.
Other medicines and Telmisartan HCT
Tell your doctor or pharmacist if you are
taking, have recently taken or might take
any other medicines. Your doctor may need
to change the dose of these other
medications or take other precautions. In
some cases you may have to stop taking one
of the medicines. This applies especially to
the medicines listed below taken at the
same time with Telmisartan HCT :
- Lithium containing medicines to treat
some types of depression.
- Medicines associated with low blood
potassium (hypokalaemia) such as other
diuretics ('water tablets'), laxatives (e.g.
castor oil), corticosteroids (e.g. prednisone),
ACTH (a hormone), amphotericin (an
antifungal medicine), carbenoxolone (used
to treat mouth ulcers), penicillin G sodium
(an antibiotic), and salicylic acid and
derivatives.
- Medicines that may increase blood
potassium levels such as potassium
-sparing diuretics, potassium supplements,
salt substitutes containing potassium, ACE
inhibitors, cyclosporin (an
immunosuppressant drug) and other
medicinal products such as heparin sodium
(an anticoagulant).
- Medicines that are affected by changes of
the blood potassium level such as heart
medicines (e.g. digoxin) or medicines to
control the rhythm of your heart (e.g.
quinidine, disopyramide, amiodarone,
sotalol),medicines used for mental disorders
(e.g. thioridazine, chlorpromazine,
levomepromazine) and other medicines
such as certain antibiotics (e.g.
sparfloxacine, pentamidine) or certain
medicines to treat allergic reactions (e.g.
terfenadine).
- Medicines for the treatment of diabetes
(insulins or oral agents such as metformin). -
Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
Cholestyramine and colestipol, medicines
for lowering blood fat levels. - Medicines to
increase blood pressure, such as
noradrenaline.
- Muscle relaxing medicines, such as
tubocurarine.
- Calcium supplements and/or vitamin D
supplements.
- Anti-cholinergic medicines (medicines
used to treat a variety of disorders such as
gastrointestinal cramps, urinary bladder
spasm, asthma, motion sickness, muscular
spasms, Parkinson’s disease and as an aid to
anaesthesia) such as atropine and biperiden.
- Amantadine (medicine used to treat
Parkinson’s disease and also used to treat or
prevent certain illnesses caused by viruses).
- Other medicines used to treat high blood
pressure, corticosteroids, painkillers (such as
non-steroidal anti-inflammatory drugs
[NSAIDs]), medicines to treat cancer, gout,
or arthritis.
- If you are taking an ACE-inhibitor or
aliskiren (see also information under the
headings “Do not take Telmisartan HCT ”
and “Warnings and precautions”).
- Digoxin.
Telmisartan HCT may increase the blood
pressure lowering effect of other medicines
used to treat high blood pressure or of
medicines with blood pressure lowering
potential (e.g. baclofen, amifostine).
Furthermore, low blood pressure may be
aggravated by alcohol, barbiturates,
narcotics or antidepressants. You may
notice this as dizziness when standing up.
You should consult with your doctor if you
need to adjust the dose of your other
medicine while taking Telmisartan HCT.
The effect of Telmisartan HCT may be
reduced when you take NSAIDs (non
steroidal anti-inflammatory medicines, e.g.
aspirin or ibuprofen).
Telmisartan HCT with food and alcohol
You can take Telmisartan HCT with or
without food. Avoid taking alcohol until you
have talked to your doctor. Alcohol may
make your blood pressure fall more and/or
increase the risk of you becoming dizzy or
feeling faint.
Pregnancy and breast-feeding
Pregnancy
You must tell your doctor if you think you
are (or might become) pregnant. Your
doctor will normally advise you to stop
taking Telmisartan HCT before you become
pregnant or as soon as you know you are
pregnant and will advise you to take
another medicine instead of Telmisartan
HCT . Telmisartan HCT is not recommended
during pregnancy, and must not be taken
when more than 3 months pregnant, as it
may cause serious harm to your baby if used
after the third month of pregnancy.
Breast-feeding
Tell your doctor if you are breast-feeding or
about to start breast-feeding.
Telmisartan HCT is not recommended for
mothers who are breast-feeding, and your
doctor may choose another treatment for
you if you wish to breast-feed.
Driving and using machines
Some people feel dizzy or tired when taking
Telmisartan HCT . If you feel dizzy or tired,
do not drive or operate machinery.
Telmisartan HCT contains lactose
monohydrate
If you are intolerant to some sugars, consult
your doctor before taking this medicinal
product.
3. How you will be given Telmisartan
HCT
Always take this medicine exactly as your
doctor has told you. Check with your doctor
or pharmacist if you are not sure.
The recommended dose of Telmisartan HCT
is one tablet a day. Try to take a tablet at the
same time each day. You can take
Telmisartan HCT with or without food. The
tablets should be swallowed with some
water or other non-alcoholic drink. It is
important that you take Telmisartan HCT
every day until your doctor tells you
otherwise.
If your liver is not working properly, the
usual dose should not exceed 40 mg/12.5
mg once a day.
If you take more Telmisartan HCT than
you should
If you accidentally take too many tablets you
may experience symptoms such as low
blood pressure and rapid heartbeat. Slow
heartbeat, dizziness, vomiting, reduced
kidney function including kidney failure,
have also been reported. Due to the
hydrochlorothiazide component, markedly
low blood pressure and low blood levels of
potassium can also happen, which may
result in nausea, sleepiness and muscle
cramps and/or irregular heartbeat
associated with the concomitant use of
drugs such as digitalis or certain anti-
Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
arrhythmic treatments. Contact your doctor,
pharmacist, or your nearest hospital
emergency department immediately.
If you forget to take Telmisartan HCT
If you forget to take a dose, do not worry.
Take it as soon as you remember then carry
on as before. If you do not take your tablet
on one day, take your normal dose on the
next day. Do not take a double dose to
make up for forgotten individual doses.
If you have further questions on the use of
this medicine, ask your doctor or
pharmacist.
4. Possible Side Effects
Like all medicines, this medicine can cause
side effects, although not everybody gets
them.
Some side effects can be serious and need
immediate medical attention:
You should see your doctor immediately if
you experience any of the following
symptoms: Sepsis* (often called "blood
poisoning"), is a severe infection with whole-
body inflammatory response, rapid swelling
of the skin and mucosa (angioedema),
blistering and peeling of the top layer of
skin (toxic epidermal necrolysis); these side
effects are rare (may affect up to 1 in 1,000
people) or of unknown frequency (toxic
epidermal necrolysis) but are extremely
serious and patients should stop taking the
medicine and see their doctor immediately.
If these effects are not treated they could be
fatal. Increased incidence of sepsis has been
observed with telmisartan only, however
cannot be ruled out for Telmisartan HCT .
Possible side effects of Telmisartan HCT:
Common side effects (may affect up to 1 in
10 people):
Dizziness.
Uncommon side effects (may affect up to 1
in 100 people):
Decreased blood potassium levels, anxiety,
fainting (syncope), sensation of tingling,
pins and needles (paraesthesia), feeling of
spinning (vertigo), fast heart beat
(tachycardia), heart rhythm disorders, low
blood pressure, a sudden fall in blood
pressure when you stand up, shortness of
breath (dyspnoea), diarrhoea, dry mouth,
flatulence, back pain, muscle spasm, muscle
pain, erectile dysfunction (inability to get or
keep an erection), chest pain, increased
blood uric acid levels.
Rare side effects (may affect up to 1 in 1,000
people):
Inflammation of the lung (bronchitis),
activation or worsening of systemic lupus
erythematosus (a disease where the body’s
immune system attacks the body, which
causes joint pain, skin rashes and fever); sore
throat, inflamed sinuses; feeling sad
(depression), difficulty falling asleep
(insomnia), impaired vision, difficulty
breathing, abdominal pain, constipation,
bloating (dyspepsia), feeling
sick(vomiting),inflammation of the stomach
(gastritis), abnormal liver function (Japanese
patients are more likely to experience this
side effect), redness of the skin (erythema),
allergic reactions such as itching or rash,
increased sweating, hives (urticaria), joint
pain (arthralgia) and pain in extremities,
muscle cramps, flu-like-illness, pain, low
levels of sodium, increased levels of
creatinine, hepatic enzymes or creatine
phosphokinase in the blood.
Adverse reactions reported with one of the
individual components may be potential
adverse reactions with Telmisartan HCT,
even if not observed in clinical trials with
this product.
Telmisartan
In patients taking telmisartan alone the
following additional side effects have been
reported:
Uncommon side effects (may affect up to 1
in 100 people):
Upper respiratory tract infection (e.g. sore
throat, inflamed sinuses, common cold),
urinary tract infections, deficiency in red
blood cells (anaemia), high potassium levels,
slow heart rate (bradycardia), kidney
impairment including acute kidney failure,
weakness, cough.
Rare side effects (may affect up to 1 in 1,000
people):
Low platelet count (thrombocytopenia),
increase in certain white blood cells
(eosinophilia), serious allergic reaction (e.g.
hypersensitivity, anaphylactic reaction, drug
rash), low blood sugar levels (in diabetic
patients), upset stomach, eczema (a skin
disorder), arthrosis, inflammation of the
tendons, decreased haemoglobin (a blood
protein), somnolence.
Very rare side effects (may affect up to 1 in
10,000 people): Progressive scarring of lung
tissue (interstitial lung disease)**
* The event may have happened by chance
Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
or could be related to a mechanism
currently not known.
** Cases of progressive scarring of lung
tissue have been reported during intake of
telmisartan. However, it is not known
whether telmisartan was the cause.
Hydrochlorothiazide
In patients taking hydrochlorothiazide alone
the following additional side effects have
been reported:
Common side effects (may affect up to 1 in
10 people):
Feeling sick (nausea), low blood magnesium
level.
Rare side effects (may affect up to 1 in 1,000
people):
Reduction in blood platelets, which
increases risk of bleeding or bruising (small
purple-red marks in skin or other tissue
caused by bleeding), high blood calcium
level, headache.
Very rare side effects (may affect up to 1 in
10,000 people):
Increased pH (disturbed acid-base balance)
due to low blood chloride level.
Side effects of unknown frequency
(frequency cannot be estimated from the
available data):
Inflammation of the salivary gland,
decreases in the number (or even lack) of
cells in the blood, including low red and
white blood cell count, serious allergic
reactions (e.g. hypersensitivity, anaphylactic
reaction), decreased or loss of appetite,
restlessness, light-headedness, blurred or
yellowing of vision, decrease in vision and
eye pain (possible signs of acute myopia or
acute-angle closure glaucoma),
inflammation of blood vessels (vasculitis
necrotising), inflamed pancreas, upset
stomach, yellowing of the skin or eyes
(jaundice), lupus-like syndrome (a condition
mimicking a disease called systemic lupus
erythematosus where the body’s immune
system attacks the body); skin disorders
such as inflamed blood vessels in the skin,
increased sensitivity to sunlight, rash,
redness of the skin, blistering of the lips,
eyes or mouth, skin and peeling , fever
(possible signs of erythema multiforme),
weakness, kidney inflammation or impaired
kidney function, glucose in the urine
(glycosuria), fever, impaired electrolyte
balance, high blood cholesterol levels,
decreased blood volume, increased blood
levels of glucose, difficulties in controlling
blood/urine levels of glucose in patients
with a diagnosis of diabetes mellitus, or fat
in the blood, Skin and lip cancer (Non-
melanoma skin cancer).
Reporting of side effects
If you get any side effects, talk to your
doctor or pharmacist. This includes any
possible side effects not listed in this leaflet.
By reporting side effects you can help
provide more information on the safety of
this medicine.
5. How Telmisartan HCT is stored
Keep this medicine out of the sight and
reach of children.
Do not use this medicine after the expiry
date which is stated on the carton or blister
after “EXP”. The expiry date refers to the last
day of that month.
This medicine does not require any special
temperature storage conditions. Store in the
original package in order to protect from
moisture.
Do not throw away any medicines via
wastewater or household waste. Ask your
pharmacist how to throw away medicines
you no longer use. These measures will help
protect the environment.
6. Further information
What Telmisartan HCT contains
The active substances are telmisartan and
hydrochlorothiazide.
Each tablet contains 40 mg telmisartan and
12.5 mg hydrochlorothiazide.
Each tablet contains 80 mg telmisartan and
12.5 mg hydrochlorothiazide.
Each tablet contains 80 mg telmisartan and
25 mg hydrochlorothiazide.
The other ingredients are: Cellulose,
microcrystalline, lactose monohydrate,
mannitol, sodium hydroxide, meglumine,
povidone (K30), magnesium stearate,
sodium stearyl fumarate, red ferric oxide
(E172) [for 40 mg/12.5 mg and 80 mg/12.5
mg tablets] and yellow ferric oxide (E172)
[for 80 mg/25 mg tablets].
What Telmisartan HCT looks like and
contents of the pack
80 mg/12.5 mg tablets: White to off white
on one side and red, possibly mottled, on
other side, biconvex, bilayer, oblong
shaped, uncoated tablets, approximately
16.2 mm in length and 7.9 mm in width.
Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
Manufactured in India by:
TAJ PHARMACEUTICALS LTD.
Mumbai, India
At: 615, GIDC, Kerala, Bavla, Dist.
Ahmedabad 438225, Gujarat, INDIA
This leaflet was last revised in August 2019

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Telmisartan hct 80mg and 12.5mg tablets pil, taj pharmaceuticals.

  • 1. Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL. TELMISARTAN HYDROCHLOROTHIAZIDE TABLETS 80 MG/12.5 MG Package leaflet: Information for the patient Telmisartan/ Hydrochlorothiazide 80mg/12.5mg Tablets. Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. - Keep this leaflet. You may need to read it again. - If you have any further questions, ask your doctor or pharmacist. - This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours. - If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor. What is in this leaflet 1. What Telmisartan HCT is and what it is used for 2. Before you are given Telmisartan HCT 3. How you will be given Telmisartan HCT 4. Possible side effects 5. How Telmisartan HCT is stored 6. Further Information 1. What Telmisartan HCT is and what it is used for Telmisartan HCT is a combination of two active substances, telmisartan and hydrochlorothiazide in one tablet. Both of these substances help to control high blood pressure. - Telmisartan belongs to a group of medicines called angiotensin II receptor antagonists. Angiotensin-II is a substance produced in your body which causes your blood vessels to narrow thus increasing your blood pressure. Telmisartan blocks the effect of angiotensin II so that the blood vessels relax, and your blood pressure is lowered. - Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics, which cause your urine output to increase, leading to a lowering of your blood pressure. High blood pressure, if not treated, can damage blood vessels in several organs, which could lead sometimes to heart attack, heart or kidney failure, stroke, or blindness. There are usually no symptoms of high blood pressure before damage occurs. Thus it is important to regularly measure blood pressure to verify if it is within the normal range. Telmisartan HCT 80 mg/12.5 mg or in patients who have been previously stabilised by telmisartan and hydrochlorothiazide given separately. 2. Before you are given Telmisartan HCT Do not take Telmisartan HCT : - if you are allergic to telmisartan or any other ingredients of this medicine (listed in section 6). - if you are allergic to hydrochlorothiazide or to any other sulfonamide-derived medicines. - if you are more than 3 months pregnant. (It is also better to avoid Telmisartan HCT in early pregnancy-see pregnancy section.) - if you have severe liver problems such as cholestasis or biliary obstruction (problems with drainage of the bile from liver and the gall bladder) or any other severe liver disease. - if you have severe kidney disease. - if your doctor determines that you have low potassium levels or high calcium levels in your blood that do not get better with treatment. - if you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren. If any of the above applies to you, tell your doctor or pharmacist before taking Telmisartan HCT . Warnings and precautions Talk to your doctor before taking this medicine if you are suffering or have ever suffered from any of the following conditions or illnesses: - Low blood pressure (hypotension), likely to occur if you are dehydrated (excessive loss of body water) or have salt deficiency due to diuretic therapy (water tablets), low-salt diet, diarrhoea, vomiting, or haemodialysis. - Kidney disease or kidney transplant. - Renal artery stenosis (narrowing of the blood vessels to one or both kidneys). - Liver disease. - Heart trouble. - Diabetes. - Gout.
  • 2. Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL. - Raised aldosterone levels (water and salt retention in the body along with imbalance of various blood minerals). - Systemic lupus erythematosus (also called “lupus” or “SLE”) a disease where the body’s immune system attacks the body. - The active ingredient hydrochlorothiazide can cause an unusual reaction, resulting in a decrease in vision and eye pain. These could be symptoms of an increase of pressure in your eye and can happen within hours to weeks of taking Telmisartan HCT. This can lead to permanent vision impairment, if not treated. Talk to your doctor before taking Telmisartan HCT : - - if you are taking any of the following medicines used to treat high blood pressure: o an ACE-inhibitor (for example enalapril, lisinopril, ramipril), in particular if you have diabetes-related kidney problems. o aliskiren. - Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g. potassium) in your blood at regular intervals. See also information under the heading “Do not take Telmisartan HCT”. - if you are taking digoxin. - if you have had skin cancer or if you develop an unexpected skin lesion during the treatment. Treatment with hydrochlorothiazide, particularly long term use with high doses, may increase the risk of some types of skin and lip cancer (non- melanoma skin cancer). Protect your skin from sun exposure and UV rays while taking Telmisartan HCT You must tell your doctor if you think you are (or might become) pregnant. Telmisartan HCT is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage (see pregnancy section). Treatment with hydrochlorothiazide may cause electrolyte imbalance in your body. Typical symptoms of fluid or electrolyte imbalance include dry mouth, weakness, lethargy, drowsiness, restlessness, muscle pain or cramps, nausea (feeling sick), vomiting, tired muscles, and an abnormally fast heart rate (faster than 100 beats per minute). If you experience any of these you should tell your doctor. You should also tell your doctor, if you experience an increased sensitivity of the skin to the sun with symptoms of sunburn (such as redness, itching, swelling, blistering) occurring more quickly than normal. In case of surgery or anaesthetics, you should tell your doctor that you are taking Telmisartan HCT . Telmisartan HCT may be less effective in lowering the blood pressure in black patients. Children and adolescents The use of Telmisartan HCT in children and adolescents up to the age of 18 years is not recommended. Other medicines and Telmisartan HCT Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Your doctor may need to change the dose of these other medications or take other precautions. In some cases you may have to stop taking one of the medicines. This applies especially to the medicines listed below taken at the same time with Telmisartan HCT : - Lithium containing medicines to treat some types of depression. - Medicines associated with low blood potassium (hypokalaemia) such as other diuretics ('water tablets'), laxatives (e.g. castor oil), corticosteroids (e.g. prednisone), ACTH (a hormone), amphotericin (an antifungal medicine), carbenoxolone (used to treat mouth ulcers), penicillin G sodium (an antibiotic), and salicylic acid and derivatives. - Medicines that may increase blood potassium levels such as potassium -sparing diuretics, potassium supplements, salt substitutes containing potassium, ACE inhibitors, cyclosporin (an immunosuppressant drug) and other medicinal products such as heparin sodium (an anticoagulant). - Medicines that are affected by changes of the blood potassium level such as heart medicines (e.g. digoxin) or medicines to control the rhythm of your heart (e.g. quinidine, disopyramide, amiodarone, sotalol),medicines used for mental disorders (e.g. thioridazine, chlorpromazine, levomepromazine) and other medicines such as certain antibiotics (e.g. sparfloxacine, pentamidine) or certain medicines to treat allergic reactions (e.g. terfenadine). - Medicines for the treatment of diabetes (insulins or oral agents such as metformin). -
  • 3. Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL. Cholestyramine and colestipol, medicines for lowering blood fat levels. - Medicines to increase blood pressure, such as noradrenaline. - Muscle relaxing medicines, such as tubocurarine. - Calcium supplements and/or vitamin D supplements. - Anti-cholinergic medicines (medicines used to treat a variety of disorders such as gastrointestinal cramps, urinary bladder spasm, asthma, motion sickness, muscular spasms, Parkinson’s disease and as an aid to anaesthesia) such as atropine and biperiden. - Amantadine (medicine used to treat Parkinson’s disease and also used to treat or prevent certain illnesses caused by viruses). - Other medicines used to treat high blood pressure, corticosteroids, painkillers (such as non-steroidal anti-inflammatory drugs [NSAIDs]), medicines to treat cancer, gout, or arthritis. - If you are taking an ACE-inhibitor or aliskiren (see also information under the headings “Do not take Telmisartan HCT ” and “Warnings and precautions”). - Digoxin. Telmisartan HCT may increase the blood pressure lowering effect of other medicines used to treat high blood pressure or of medicines with blood pressure lowering potential (e.g. baclofen, amifostine). Furthermore, low blood pressure may be aggravated by alcohol, barbiturates, narcotics or antidepressants. You may notice this as dizziness when standing up. You should consult with your doctor if you need to adjust the dose of your other medicine while taking Telmisartan HCT. The effect of Telmisartan HCT may be reduced when you take NSAIDs (non steroidal anti-inflammatory medicines, e.g. aspirin or ibuprofen). Telmisartan HCT with food and alcohol You can take Telmisartan HCT with or without food. Avoid taking alcohol until you have talked to your doctor. Alcohol may make your blood pressure fall more and/or increase the risk of you becoming dizzy or feeling faint. Pregnancy and breast-feeding Pregnancy You must tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Telmisartan HCT before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Telmisartan HCT . Telmisartan HCT is not recommended during pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy. Breast-feeding Tell your doctor if you are breast-feeding or about to start breast-feeding. Telmisartan HCT is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed. Driving and using machines Some people feel dizzy or tired when taking Telmisartan HCT . If you feel dizzy or tired, do not drive or operate machinery. Telmisartan HCT contains lactose monohydrate If you are intolerant to some sugars, consult your doctor before taking this medicinal product. 3. How you will be given Telmisartan HCT Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. The recommended dose of Telmisartan HCT is one tablet a day. Try to take a tablet at the same time each day. You can take Telmisartan HCT with or without food. The tablets should be swallowed with some water or other non-alcoholic drink. It is important that you take Telmisartan HCT every day until your doctor tells you otherwise. If your liver is not working properly, the usual dose should not exceed 40 mg/12.5 mg once a day. If you take more Telmisartan HCT than you should If you accidentally take too many tablets you may experience symptoms such as low blood pressure and rapid heartbeat. Slow heartbeat, dizziness, vomiting, reduced kidney function including kidney failure, have also been reported. Due to the hydrochlorothiazide component, markedly low blood pressure and low blood levels of potassium can also happen, which may result in nausea, sleepiness and muscle cramps and/or irregular heartbeat associated with the concomitant use of drugs such as digitalis or certain anti-
  • 4. Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL. arrhythmic treatments. Contact your doctor, pharmacist, or your nearest hospital emergency department immediately. If you forget to take Telmisartan HCT If you forget to take a dose, do not worry. Take it as soon as you remember then carry on as before. If you do not take your tablet on one day, take your normal dose on the next day. Do not take a double dose to make up for forgotten individual doses. If you have further questions on the use of this medicine, ask your doctor or pharmacist. 4. Possible Side Effects Like all medicines, this medicine can cause side effects, although not everybody gets them. Some side effects can be serious and need immediate medical attention: You should see your doctor immediately if you experience any of the following symptoms: Sepsis* (often called "blood poisoning"), is a severe infection with whole- body inflammatory response, rapid swelling of the skin and mucosa (angioedema), blistering and peeling of the top layer of skin (toxic epidermal necrolysis); these side effects are rare (may affect up to 1 in 1,000 people) or of unknown frequency (toxic epidermal necrolysis) but are extremely serious and patients should stop taking the medicine and see their doctor immediately. If these effects are not treated they could be fatal. Increased incidence of sepsis has been observed with telmisartan only, however cannot be ruled out for Telmisartan HCT . Possible side effects of Telmisartan HCT: Common side effects (may affect up to 1 in 10 people): Dizziness. Uncommon side effects (may affect up to 1 in 100 people): Decreased blood potassium levels, anxiety, fainting (syncope), sensation of tingling, pins and needles (paraesthesia), feeling of spinning (vertigo), fast heart beat (tachycardia), heart rhythm disorders, low blood pressure, a sudden fall in blood pressure when you stand up, shortness of breath (dyspnoea), diarrhoea, dry mouth, flatulence, back pain, muscle spasm, muscle pain, erectile dysfunction (inability to get or keep an erection), chest pain, increased blood uric acid levels. Rare side effects (may affect up to 1 in 1,000 people): Inflammation of the lung (bronchitis), activation or worsening of systemic lupus erythematosus (a disease where the body’s immune system attacks the body, which causes joint pain, skin rashes and fever); sore throat, inflamed sinuses; feeling sad (depression), difficulty falling asleep (insomnia), impaired vision, difficulty breathing, abdominal pain, constipation, bloating (dyspepsia), feeling sick(vomiting),inflammation of the stomach (gastritis), abnormal liver function (Japanese patients are more likely to experience this side effect), redness of the skin (erythema), allergic reactions such as itching or rash, increased sweating, hives (urticaria), joint pain (arthralgia) and pain in extremities, muscle cramps, flu-like-illness, pain, low levels of sodium, increased levels of creatinine, hepatic enzymes or creatine phosphokinase in the blood. Adverse reactions reported with one of the individual components may be potential adverse reactions with Telmisartan HCT, even if not observed in clinical trials with this product. Telmisartan In patients taking telmisartan alone the following additional side effects have been reported: Uncommon side effects (may affect up to 1 in 100 people): Upper respiratory tract infection (e.g. sore throat, inflamed sinuses, common cold), urinary tract infections, deficiency in red blood cells (anaemia), high potassium levels, slow heart rate (bradycardia), kidney impairment including acute kidney failure, weakness, cough. Rare side effects (may affect up to 1 in 1,000 people): Low platelet count (thrombocytopenia), increase in certain white blood cells (eosinophilia), serious allergic reaction (e.g. hypersensitivity, anaphylactic reaction, drug rash), low blood sugar levels (in diabetic patients), upset stomach, eczema (a skin disorder), arthrosis, inflammation of the tendons, decreased haemoglobin (a blood protein), somnolence. Very rare side effects (may affect up to 1 in 10,000 people): Progressive scarring of lung tissue (interstitial lung disease)** * The event may have happened by chance
  • 5. Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL. or could be related to a mechanism currently not known. ** Cases of progressive scarring of lung tissue have been reported during intake of telmisartan. However, it is not known whether telmisartan was the cause. Hydrochlorothiazide In patients taking hydrochlorothiazide alone the following additional side effects have been reported: Common side effects (may affect up to 1 in 10 people): Feeling sick (nausea), low blood magnesium level. Rare side effects (may affect up to 1 in 1,000 people): Reduction in blood platelets, which increases risk of bleeding or bruising (small purple-red marks in skin or other tissue caused by bleeding), high blood calcium level, headache. Very rare side effects (may affect up to 1 in 10,000 people): Increased pH (disturbed acid-base balance) due to low blood chloride level. Side effects of unknown frequency (frequency cannot be estimated from the available data): Inflammation of the salivary gland, decreases in the number (or even lack) of cells in the blood, including low red and white blood cell count, serious allergic reactions (e.g. hypersensitivity, anaphylactic reaction), decreased or loss of appetite, restlessness, light-headedness, blurred or yellowing of vision, decrease in vision and eye pain (possible signs of acute myopia or acute-angle closure glaucoma), inflammation of blood vessels (vasculitis necrotising), inflamed pancreas, upset stomach, yellowing of the skin or eyes (jaundice), lupus-like syndrome (a condition mimicking a disease called systemic lupus erythematosus where the body’s immune system attacks the body); skin disorders such as inflamed blood vessels in the skin, increased sensitivity to sunlight, rash, redness of the skin, blistering of the lips, eyes or mouth, skin and peeling , fever (possible signs of erythema multiforme), weakness, kidney inflammation or impaired kidney function, glucose in the urine (glycosuria), fever, impaired electrolyte balance, high blood cholesterol levels, decreased blood volume, increased blood levels of glucose, difficulties in controlling blood/urine levels of glucose in patients with a diagnosis of diabetes mellitus, or fat in the blood, Skin and lip cancer (Non- melanoma skin cancer). Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. By reporting side effects you can help provide more information on the safety of this medicine. 5. How Telmisartan HCT is stored Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton or blister after “EXP”. The expiry date refers to the last day of that month. This medicine does not require any special temperature storage conditions. Store in the original package in order to protect from moisture. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. 6. Further information What Telmisartan HCT contains The active substances are telmisartan and hydrochlorothiazide. Each tablet contains 40 mg telmisartan and 12.5 mg hydrochlorothiazide. Each tablet contains 80 mg telmisartan and 12.5 mg hydrochlorothiazide. Each tablet contains 80 mg telmisartan and 25 mg hydrochlorothiazide. The other ingredients are: Cellulose, microcrystalline, lactose monohydrate, mannitol, sodium hydroxide, meglumine, povidone (K30), magnesium stearate, sodium stearyl fumarate, red ferric oxide (E172) [for 40 mg/12.5 mg and 80 mg/12.5 mg tablets] and yellow ferric oxide (E172) [for 80 mg/25 mg tablets]. What Telmisartan HCT looks like and contents of the pack 80 mg/12.5 mg tablets: White to off white on one side and red, possibly mottled, on other side, biconvex, bilayer, oblong shaped, uncoated tablets, approximately 16.2 mm in length and 7.9 mm in width.
  • 6. Telmisartan/Hy drochlorot hiazide 80 mg/12.5 mg tablets, Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warning s, Telmisartan HCT Dosage & Rx Info | Telmisartan HCT Uses, Side Effects – Antifungal/ Antibacterial, Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg tablets: Indications, Side Effects, Warnings, Telmisartan HCT - Drug Information - Taj Pharma, Telmisartan HCT dose Taj pharmaceuticals Telmisartan HCT interactions, Taj Pharmaceutical Telmisartan HCT contraindications, Telmisartan HCT price, Telmisartan HCT , Taj Pharma Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg t ablets, - Taj Pharma . Stay connected to all updated on Telmisartan HCT Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL. Manufactured in India by: TAJ PHARMACEUTICALS LTD. Mumbai, India At: 615, GIDC, Kerala, Bavla, Dist. Ahmedabad 438225, Gujarat, INDIA This leaflet was last revised in August 2019