1. DECEM BER 2 0 0 4 OM NI LUX, LEADER S I N LI GHT THER AP Y
L I G H T S O U R C E
I N S I D E T H I S I S S U E :
E A D V 2 0 0 6 / 2 0 0 7 1
A R O U N D T H E
W O R L D
2
W E B I N A R S P R O V E A
S U C C E S S
2
O M N I L U X
P U B L I S H E D
3
N E W L I G H T O N
B L U E L E D S
4
U K S O E A W A R D S 4
P U B L I C A T I O N L I S T 5
Welcome to the 6th
issue of Light Source. Already we find ourselves at the halfway point of the
year. Sales of Omnilux continue to rise and our US operation in Lake Forest California is
beginning have a positive impact in this market. The US is always seen as the leader in
aesthetic technologies and our successful presence in this market will, I am sure, bring benefits
to us all as doctors inevitably follow new and novel developments that are a success in the US.
I would like to take this opportunity to thank all distributors who have been extremely patient
during the process of moving to a new manufacturer. As you will imagine this has been a very
difficult period, but we hope that this transition will improve product quality and reliability.
To those distributors venturing to the island of Rhodes in October for the 15th
annual EADV
meeting, I will of course look forward to meeting you. Until then, good luck in Quarter 3.
Sue D’Arcy, C.E.O.
ISSUE 6
C O N G R A T U L A T I O N S T R A C Y
The 15th EADV Congress in 2006 migrates to Rhodes, Greece, from the 4th until the 8th of October,
promoted under the title; "From Hippocrates to Modern Dermatology." It is the largest European Derma-
tology conference and Omnilux will be show casing our most recent protocols and applications. Please
visit us on booth number 119.
Omnilux will also be represented within the academic programme, with talks by Dr Mario Trelles,
“Improvements in Cutaneous Conditions with LED Therapy” and as part of the Phototherapy session chaired by Dr Mario Trelles,
Dr Glen Calderhead will present on "The Role of Light Emitting Diodes in Phototherapy". To register for the meeting, please visit;
www.eadv2006.com
Please also note that the EADV 2007 will be held in Vienna, 16th-20th May, (www.eadvvienna2007.com). The 21st World
Congress of Dermatology will be held in October in Buenos Aires - Argentina. For more details log onto; www.dermato2007.org
If you have any news of your exhibitions and meetings, please send us any details and photographs and we will post them on the
website and feature them in our Lightsource Newsletter.
E A D V H E A D S F O R R H O D E S - O C T O B E R 2 0 0 6
June 2006 was both a happy and sad month for Tracy May and Omnilux.
June 3rd
saw Tracy (our beauty development manager) wed Jason
Harriott in a beautiful village church in their hometown, followed by a
honeymoon in Aruba in the West Indies. However, June also saw Tracy
leave Omnilux after five years as a full time member of staff. Tracy will be
starting on a new venture, although she will consult for Omnilux on a part-
time basis. She will be sadly missed by us all, not only Omnilux staff but
also distributors who she met during her time with Omnilux.
We wish her the very best of luck!

2. A R O U N D T H E W O R L D W I T H O M N I L U X
During May Genop healthcare (South Africa) staged its first
Omnilux roadshow. The roadshow was organised over 3
nights, 16th
-18th
May in 3 major cities, Johannesberg, Durban
and Cape Town and saw over 120 dermatologists and plastic
surgeons attend.
The roadshow took the form of a one hour presentation on
LED technology by Dr Glen Calderhead with time for group
discussion and questions. Participants not only enjoyed the
informative presentation, but were also treated to a fine 3
course meal set in wonderful surroundings.
To obtain a copy of Dr Glen Calderhead’s presentation go
online at www.omnilux.co.uk and click on the newslink.
Following on from the successful Omnilux roadshow, Genop
Healthcare also organised Omnilux specific workshop events
at the South African Dermatology congress In Durban, 24-
27th
May, culminating in a full one day workshop on the 26th
May. The workshop was well attended and featured ALA-
PDT photopeels of the face and chest areas for sun damage
and the treatment of extensive Basal cell carcinomas and
widespread Actinic keratosis using Pain blocks. The pain
blocks were carried out as part of the live demo by Dr Deon
van der Westhuizen, a Plastic surgeon in Cape Town.
Special thanks to Dr Dagmar Whittaker, (Cape Town) and Dr
Dhillon Naidu (Durban) and the staff of Dr Len Nels clinic in
Durban who not only demonstrated lesion preparation and
treatment, but were on hand to answer any questions from
the audience.
For those with a special interest in pain block techniques for
extensive treatment of non melanoma skin cancer lesions
with PDT an mpeg video is available of the workshop.
Dr Glen Calderhead was the invited guest speaker at the
inaugural meeting of the Asian Academy of Anti-aging
and Aesthetic Medicine held in the Prima Hotel, Seoul,
June 24th & 25th. The subject of his talk was 'The Medi-
cine of the New Millennium: Antiageing with LED
Phototherapy'. The core concept of the study was to
treat younger patients as prophylaxis against the various
insults associated with photoageing so that their skin
would become 'ageing-resistant' and they would
therefore be able to last longer before having to undergo
nonablative skin rejuvenation. The main treatment
regimen was the combination of Omnilux plus and
Omnilux revive incorporated in a comprehensive regimen
of skin- and life-care strategies. It was voted one of the
best presentations.
Also the International Phototherapy Association (IPTA)
held their inaugural meeting in Suwa City, Nagano,
Japan on June 30th - July 3rd. In addition to laser
therapy and exogenous PDT, endogenous PDT with blue
LED therapy and LEDs in general occupied a large slice
of the meeting. Mary Dyson attended from the UK, and
talked about the macrophage, adding that near IR light
was a very good stimulant, and that further studies with
LEDs would be very interesting. Mario Trelles was to
have presented on LED phototherapy for postoperative
pain and LED therapy for postoperative wound healing,
but unfortunately other commitments meant that Dr Glen
Calderhead presented his work.
20th
June 9pm EST, saw Dr
David Goldberg present live via
web based conferencing, his
talk entitled “Omnilux fact not
fiction.” An overview of Omnilux
technology included his recently
published work on acne,
(Goldberg D, Russell B Journal
of Cosmetic and Laser Therapy.
2006; 8: 71-75) and skin rejuvenation. The audio and video
portions of the presentation will be available soon in the
news section of the website.
Look out for future presentations @ www.Omnilux.co.uk
(From left to right) Dr Dagmar Whittaker (Cape Town), Dr Glen
Calderhead and Mrs Diane Rix of Genop Healthcare.
W E B I N A R S P R O V E A S U C C E S S

3. Quarter 2 saw the long awaited publication of the manuscript
entitled Combination blue (415 nm) and red (633 nm) LED
phototherapy in the treatment of mild to severe acne vulgaris.
The paper appears in the Journal of Cosmetic and Laser
Therapy. 2006; 8: 71–75. Below is the abstract as it appears in
the journal.
‘Acne vulgaris represents both a challenge to the treating
dermatologist and a major concern for the patient.
Conventional treatments have proved inconsistent with often
unacceptable side effects and high rates of recurrence.
Non-thermal, non-laser, phototherapy for acne with a
combination of blue and red light has recently attracted
attention.
The present study was designed to assess the efficacy of this
combination phototherapy.
Twenty-four subjects, Fitzpatrick skin types II–V, with mild to
severe symmetric facial acne vulgaris were recruited for the
study. Subjects were well matched at baseline in terms of both
age and duration of acne. Subjects were treated over eight
sessions, two per week 3 days apart, alternating between 415
nm blue light (20 minutes/session, 48 J/cm2) and 633 nm red
light (20 minutes/session, 96 J/cm2) from a light-emitting diode
(LED)-based therapy system. Patients received a mild
microdermabrasion before each session. Acne was assessed
at baseline and at weeks 2, 4, 8 and 12.
Twenty-two patients completed the trial. A mean reduction in
lesion count was observed at all follow-up points. At the
4-week follow-up, the mean lesion count reduction was
significant at 46% (p50.001). At the 12-week follow-up, the
mean lesion count reduction was also significant at 81%
(p>0.001). Patient and dermatologist assessments were
similar. Severe acne showed a marginally better response
than mild acne. Side effects were minimal and transitory.
Comedones did not respond as well as inflammatory lesions.
Conclusions: Combination blue and red LED therapy appears
to have excellent potential in the treatment of mild to severe
acne. Treatment appears to be both pain- and side effect-free.’
C O M B I N A T I O N T H E R A P Y F O R A C N E P U B L I S H E D !
Following on from the successful paper by Drs Omi and
Takezaki, the research team from the Department of
Dermatology, J Nippon Medical School, Tokyo, Japan, have
published further work on the effect of red light therapy on skin
homing T cells. Skin-homing T-cells are an important part of
the body's immune defense system to any invasion
(pathogens or allergens) through the skin. They are found in
the lymph nodes, and are activated when any bacteria or
allergy-related substance attacks the dermis through the
epidermis, moving to the target area through chemotaxis, (the
ability to move to a particular site via chemical signaling). They
then help with the attack on the invading materials or cells,
and also help to control the inflammatory response.
Red light phototherapy with laser sources has been used
successfully for a number of indications. A new generation of
quasimonochromatic 630 +/- 3 nm light-emitting diode (LED)
systems has recently been yielding good results for the same
indications, but no study has examined changes in visible red
light irradiated skin at an immunological level. This study was
thus designed to examine changes in skin-homing T-cell levels
induced in normal human skin by visible red LED energy. Six
adult male volunteers (35 to approximately 48 years old) who
satisfied all study criteria had the skin over the lateral aspect
of the leg irradiated once per week for 8 weeks with a visible
red (630 +/- 3 nm) LED-based system, with irradiance of 105
m/cm2
, 15 minutes/session, and a radiant flux of 94 J/cm2
.
Skin biopsies were performed after the eighth treatment
session, and cultures were prepared to assay the type and
quantity of skin-homing T-cells using qualitative and
quantitative polymerase chain reaction (PCR) techniques.
Ultrastructural changes were also assessed with transmission
electron microscopy. The results showed that transmission
electron microscopy revealed mild fibroplastic changes in
fibroblasts, with no acute inflammatory changes throughout
the treatment sessions. Qualitative PCR showed the presence
of both Th-1 and Th-2 T-cells, and quantitative PCR showed
an increase in the numbers of both types of skin-homing
T-cells, much more so for Th-2 than for Th-1. In conclusion
visible red LED irradiation appears to activate the skin-homing
immune system.
(Takezaki S, Omi T, Sato S, Kawana S: Light-emitting diode
phototherapy at 630 +/- 3 nm increases local levels of
skin-homing T-cells in human subjects. J Nippon Medical
School, 2006; 73: 75-81.)
I N V I T R O S T U D I E S P U B L I S H E D

4. Cosmeceuticals hosted its Salon of Excellence awards at
Alton Towers, Staffordshire, UK on May 14th and 15th. The
event saw the top 100 salons across the UK attend the
weekend. Not only was the programme informative with
Omnilux being represented on the podium by both Dr Glen
Calderhead and Tracy May, but the weekend also saw
participants have the freedom of the theme park, a well earned
treat after all their hard work. The weekend also featured
numerous workshops plus a glittering Gala dinner, where the
Salon of Excellence awards were presented. Congratulations
go to Esque DaySpa, the winner of the Salon of Excellence
awards. Sally Selby, owner of Esque was so pleased with the
award and explained what a valuable investment Omnilux was
for her business. Sally enthused that; “Omnilux is one of the
most important developments in high-technology treatments
available in salons, which gives my clients the results that they
so desperately want”.
U K S A L O N O F E X C E L L E N C E A W A R D S 2 0 0 6
(From left to right) Tracy Parkin, Sales Director of Cosmeceuti-
cals UK, Dr Glen Calderhead and Charlotte Field, Brand
Manager for Cosmeceuticals UK enjoy the awards ceremony.
It is with great pleasure that PTL welcomes Astraco (Thailand)
Ltd as its medical distributor for Omnilux in Thailand. Astraco
Ltd market and sell hi -tech medical equipment into a number
of Far Eastern markets, and PTL believe that the recent
re-organisation and re-structuring of
their management team in Thailand
will drive growth of Omnilux sales
and brand awareness. We wish
Nareerat Charoenvutiwongsa and
her team all success for the future.
Good Selling!!! www.koor.com
Some recent events have indicated that not all distributors
have in place or are following an adverse event procedure.
As part of our quality systems we require ALL of our
distributors to adhere to an adverse events procedure, be it
your own or the system that we use here at Omnilux. To com-
ply with U.K. legislation we as a company must be able to
prove that our distributors, from all countries, can report an
adverse event within 24hrs, can supply an initial report within
the deadline and send regular reports of all adverse events.
For more information regarding the Adverse Events policy
please contact Steve Hutson, Steve.Hutson@omnilux.co.uk
or log onto our website and go the distributor section. The
adverse event reporting procedure and forms are contained
within the safety and regulatory affairs section.
The Omnilux website is currently undergoing a major change
to help you keep up-to-date on all Omnilux developments. We
have updated our distributor section to include our recent
publications, trade editorials and new marketing material, all
contained within the Sales and Marketing section. All of our
FDA approvals are now currently listed in the Safety and
Regulatory section.
To access the site, click on the Distributor section at www.
Omnilux.co.uk At the Login page you will be prompted for the
username; distrib06 and a password; 06pdt06
A S T R A C O T H A I L A N D J O I N S
O M N I L U X F A M I L Y
A D V E R S E E V E N T S
W E B S I T E U P G R A D E S

5. O M N I L U X I N T H E P R E S S
Recently Published:
Goldberg DG, Russell B: ‘Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild
to severe acne vulgaris’. - Journal of Cosmetic and Laser Therapy. 2006; 8: 71–75.
Takezaki S, Omi T, Sato S, Kawana S: ‘Light-emitting diode phototherapy at 630 +/- 3 nm increases local levels of
skin-homing T-cells in human subjects.’ J Nippon Medical School, 2006; 73: 75-81.
Trelles M & Allones I: ‘Red light-emitting diode (LED) therapy accelerates wound healing post-blepharoplasty and
periocular laser ablative resurfacing’. - Journal of Cosmetic and Laser Therapy. 2006; 8: 39–42.
Tremblay JF, Sire DJ, Lowe NJ & Moy RL; ‘Light-emitting diode 415 nm in the treatment of Inflammatory acne’ -
Journal of Cosmetic and Laser Therapy. 2006; 8: 31-33.
Babilas P et al ‘In vitro and in vivo comparison of two different light sources for topical photodynamic therapy’ -
British Journal of Dermatology. 2006; 154, 712 - 718.
Kim JW. ‘Synergic Effect of Ablating Erbium Yag Laser Skin Resurfacing Combined with Non Ablating Quasilaser
Light 425nm, 633nm, 830nm LED Array in Asian Patients.’ - Journal of the Korean Society for Laser Medicine and
Surgery. Vol 9: 1; 63-68.
Kim JW. ‘Clinical trial of Non thermal 633nm Omnilux LED array for renewal of Photoaging : Clinical Surface
Profilometric Results.’ - Journal of the Korean society for Laser Medicine and Surgery. Vol 9: 1; 69-76.
Kim JW. ‘The improvement of Hypertrophic Scar and Keloid Scars using a combination of Carbon Dioxide Laser and
Omnilux LED.’ - Journal of the Korean Society for Laser Medicine and Surgery. Vol 9: 1; 77-85.
Submitted for Peer review:
Kubota J et al (2005) - ‘Combined LED phototherapy in the Japanese skin type’. - Journal of Cosmetic Dermatology
Submitted 18th July 2005. Under review.
Chin S (2006) ‘A study to determine the efficacy of combination light therapy (633 nm + 830 nm) in facial skin rejuve-
nation’. - Journal of the American Academy of Dermatology. April 2006.
Kubota J (2006) ‘Combination LED therapy for skin rejuvenation in the Japanese patient: a preliminary study.’ -
Journal of Photomedicine and Laser Surgery. Submitted May 2006.
Kubota J & Chun J (2006) ‘A multi-centre trial of combination LED therapy (830 nm + 633 nm) for facial skin rejuve-
nation in Asian skin’. - Journal of Cosmetic Dermatology. Submitted May 2006.
Trelles MA, Calderhead RG and Mordon S ‘The role of phototherapy in skin rejuvenation’ - Lasers Med Science.
Submitted July 2006.
For a complete listing of all Omnilux publications either visit our website; www.omnilux.co.uk and click on the relevant
newslink or e-mail Steve.Baker@Omnilux.co.uk.
Photo Therapeutics Ltd, Unit 3, Bonehill Mews, Lichfield Street, Fazeley, Tamworth, Staffordshire, B78 3QU
Tel: 0044 1827 2528 30, Fax: 0044 1827 2873 91, E-mail: Sales@Omnilux.co.uk
www.omnilux.co.uk