2. FNAC - definition
Aspiration of cells/ tissue fragments using
fine needles (21, 22 , 23, 25 Gauge) ;
external diameter 0.6 to 1.0 mm
1.5 inches long needle ( radiologists use
longer needles)
Diagnostic materials in the needle and
not in the syringe even in cystic lesions
3. Clinical skill required
Familiarity with general anatomy eg
thyroid vs other neck swelling
Ability to take a focused clinical
history
Sharp skill in performing physical
examination eg solid vs cystic,
benign vs maligant lesions
4. Clinical skill required -2
Good knowledge in normal cellular
elements from various organs and
tissue and how they appear on
smears eg fats cells vs breast
tumour cells
Comprehensive knowledge of
surgical pathology
5. Clinical skill required -3
Ability to translate traditional tissue
patterns of lesions to their
appearance in smears
8. Who should do FNA?
Clinicians
Cytotechnologists
Radiologists
Pathologists
The one who examines the patients , does the aspiration,
makes the smears, interprets the cytology
is the best one to do FNA -
PATHOLOGIST
9. Cont:
Ideal is specialist physician to
conduct the procedure
Eg: transthorasic biopsy –by
radiologist with guidance of USS or
CT guided,
Brain biopsy by neurosurgeon
Transbronchial biopsy by
pulmonologist in the bronchoscopy
suite
10. Current status
Palpable lesions
Outpatients , in- patients
Thyroid , breast, lymph nodes,
salivary glands , soft tissue lumps...
Lung, intra-abdominal and
retroperitoneal by radiologic imaging
: CT, ultrasound, flouroscopy
,endoscopy
11. LIMITATIONS
Soft vs hard ( bone) lesions
Solid vs cystic lesions
Poor cellular yield vs poor technique
Reactive vs specific diseases eg
reactive lymphadenitis vs Hodgkins
disease
Diffuse vs nodular lymphoma
15. ADVANTAGES
Fast - early diagnosis
Less pain, less trauma, minimal
discomfort to patient
No anaesthesia
Acceptable by patients and doctors
Accurate, early diagnosis
Low risk of morbidity and mortality
Low cost
16. Cont:
False- negative rate of FNAC is 3%-
5% due to sampling problems rather
than interpretative error
It can lead to specific diagnosis in
more than 90%
17. How to interpret?
Aspiration materials eg colloid,
blood, mucus?
Cellular yield vs acellular yield
Smear pattern - 3 dimensional balls
vs flat monolayered sheet os cells
Cohesiveness vs discreet cells
Cell morphometry
18. The nurse’s role
Involved in care through the entire
process, first contact until discharge
Patient education
Explain the procedure, answer the
questions
Screening for coagulation such as
PT, aPTT and conduct , Review prior
to procedure
History, current medication eg:
warfarin , asprin
19. Nurse’s role cont:
Along with the physician informed
consent and sign forms.
Complete nurse’s documents
When starts, responsible for
monitoring the patient. Either
administers the drug accordingly
Vital signs
20. Nurse’s role cont:
Provide emotional support as needed
Direct the specimen and request
necessary test which advised by the
doctor.
Once completed, dresses puncture
site with adhesive dressing
Continues to assess the site for
bleeding or swelling
if major organ or sedation involves
pt need to recover least 30 min
21. Nurse’s role cont:
Checking the patient’s vital sign till
discharge
Provide the discharge instructions
and answer any questions
22. Future directions
Aspirating non palpable lesions
using MRI
Molecular pathology eg In Situ
Hybridization
Replacing diagnostic surgical
pathology?
Combined with MRI - replacing
autopsy?
23. Future Direction
Genomics and proteomics in DNA
and protein typing
Polymerase chain reaction
Thus practice of FNAC continues to
evolve, with investigation and
innovation focused on several areas
24. SUMMERY
FNAC is simple, accurate, fast
economical procedure that
frequently offers a viable alternative
diagnostic modality to surgery
Presence of nurse during procedure
ensure patient’s comfort and safety
and positive experience for the
patient and other health care
professionals involved