2. Alcohol and its Effects on the Brain
Alcohol can produce detectable impairments in
memory after only a few drinks and, as the amount
of alcohol increases, so does the degree of
impairment.
Large quantities of alcohol, especially when
consumed quickly and on an empty stomach, can
produce a blackout, or an interval of time for which
the intoxicated person cannot recall key details of
events, or even entire events.
3. Brain Damage with
Chronic Alcohol Use Disorder
The symptoms of Wernicke’s encephalopathy include
mental confusion, paralysis of the nerves that move the
eyes (i.e., oculomotor disturbances), and difficulty with
muscle coordination.
Thiamine deficiency (B1)
meat and poultry; whole grain cereals; nuts; and
dried beans, peas, and soybeans.
Korsakoff’s psychosis-a chronic and debilitating
syndrome characterized by persistent learning and
memory problems (can’t remember past events or
create new memories)
4. Schematic Drawing of the Human
Brain:
regions vulnerable to alcoholism-related
abnormalities
The brain stem controls basic functions
critical to life, such as heart rate,
breathing, and sleeping.
The limbic system contains the brain’s
reward circuit—it links together a number of
brain structures that control and regulate
our ability to feel pleasure
The cerebral cortex is divided into areas that
control specific functions.
5. Damage
Drinking a lot over a long time or too much on a single
occasion can damage the body, causing problems
including
Cardiomyopathy –
Stretching and drooping
of heart muscle
Arrhythmias – Irregular
heart beat
Stroke
High blood pressure
Steatosis, or fatty liver
Alcoholic hepatitis
Fibrosis
Cirrhosis
HEART LIVER
6. PANCREAS IMMUNE SYSTEM
Weaken your immune system,
making your body a much
easier target for disease.
Chronic drinkers are at risk for
pneumonia and tuberculosis
than non drinkers.
Drinking a lot on a single
occasion slows your body’s
ability to ward off infections –
even up to 24 hours after
getting drunk.
Pancreatitis = a
dangerous inflammation
and swelling of the blood
vessels in the pancreas
that prevents proper
digestion.
7. Increase Risk of Developing
Certain Cancers
Mouth
Esophagus
Throat
Liver
Breast
8. Exercise as a Useful Intervention to Reduce Alcohol
Consumption and Improve Physical Fitness in Individuals
With Alcohol Use Disorder: A Systematic Review and
Meta-Analysis
Objective
This meta-analysis and
systematic review
examined the effects of
exercise interventions
on alcohol
consumption and
binge drinking in
individuals with
alcohol use disorder
(AUD).
Data Sources
PubMed, Web of Science,
Google Scholar,
SPORTDiscus, and ERIC
databases.
9. Study Inclusion and Exclusion Criteria:
Peer-reviewed randomized controlled trials published in
English between 1970 and 2021.
All studies compared exercise (Ex) and treatment as
usual (TAU) to TAU in adults with an alcohol-related
diagnosis.
All forms of exercise interventions were included (e.g.,
aerobic exercise, yoga, resistance exercise, etc.).
10. Results: The literature searches retrieved a combined 2527 studies,
with 1,034 studies screened after removal of duplicates and 973
(94%) rejected after reviewing titles and abstracts.
Full-text review was performed on 61 studies, with seven studies
meeting inclusion criteria for qualitative and meta-analysis.
Across seven studies (n = 492 participants), a significant effect (Z-
value = −3.37; g = −0.30; 95% CI [−0.50—−0.09]; p = 0.001) was
found for Ex+TAU on drinking volume.
There was no effect of Ex+TAU on binge drinking.
The effect of Ex+TAU on physical fitness (VO2max, ml•kg−1•min−1)
was significant (Z-score = 3.70; g = 0.64; 95% CI [0.19–1.08]; p <
0.001).
11. Conclusion
Exercise interventions may decrease alcohol
consumption and improve fitness and can be an effective
adjunctive treatment for individuals with alcohol-related
diagnoses including AUD.
12. Cannabis Use
Most commonly used illicit drug in the US
Subjective “high”
Carcinogens present in all smokes
13. THE IMPACT OF CANNABIS USE ON
HEALTH
Cannabis And Physical Health
Increased risk of heart attack
Expand blood vessels in eyes
Increased blood pressure and heart rate
Breathing problems
Problems with child development
Relax and enlarge breathing passages
Short and long term effects on the brain
Impaired body movements
14. Cannabis And Mental Health
Altered senses and sense of time
Anxiety
Mood changes
Depression
Difficulty with thinking and problem solving
Impaired memory
Suicidal thoughts
Reduced life satisfaction
15. STIMULANTS
Increase alertness, attention and energy
Elevate blood pressure, heart rate & respiration
Examples
Amphetamines
Methamphetamines
Cocaine
Caffeine (most common stimulant used daily)
17. Frates B, Bonnet JP, Joseph R, Peterson JA. Substance
Abuse. In: Frates B, ed. Lifestyle Medicine Handbook:
An Introduction to the Power of Healthy Habits.
Monterey, CA: Healthy Learning; 2021:417.
Editor's Notes
Alcohol and other drugs have specific and long-lasting effects on the brain. Introducing alcohol and other substances during adolescence has lasting consequences because the brain is still developing.
he limbic system is responsible for our perception of other emotions, both positive and negative, which explains the mood-altering properties of many substances.
he front of the cortex, the frontal cortex or forebrain, is the thinking center of the brain; it powers our ability to plan, solve problems, and make decisions. Since this part of the brain is developing rapidly during adolescence, this may help explain why adolescents are more likely to engage in risky behaviors like using alcohol and other drugs (NIDA, 2007).
When you drink alcohol, your body breaks it down into a chemical called acetaldehyde. Acetaldehyde damages your DNA and prevents your body from repairing the damage. DNA is the cell’s “instruction manual” that controls a cell’s normal growth and function. When DNA is damaged, a cell can begin growing out of control and create a cancer tumor.
The word cannabis refers to all products derived from the plant Cannabis Sativa.containing 540 chemical substances.
Why subjectively high its because most people experience pleasant euphoria and sense of relaxation.
stimulants are a class of drugs that speed up messages travelling between the brain and body. They can make a person feel more awake, alert, confident or energetic.
Opioids are a class of drugs naturally found in the opium poppy plant