5. Effects of Pregnancy on Bitch
Cardiovascular
Increased cardiac workload
Aortocaval compression → supine hypertension
Respiratory
Decreased total lung volume and function
Higher O2 demand to CO2 production
Rapid desaturation → hypoxaemia
Gastrointestinal
Delayed gastric emptying with decreased oesophageal sphincter tone
Neurological
~35% increased sensitivity to anaesthetic agents
Changes in Progesterone and Beta Endorphin levels have Sedative Effects
Haematology
Decreased HCT
6. Anaesthetic Effects on Pups In Utero
Placental transfer of drugs to pups
Cross the blood-brain barrier
Respiratory Depression
Hypotension
Bradycardia
Drug transfer from milk
• (Little research in dogs)
7. Anaesthetic Aims
Be cautious of drug overdoses
Decrease drug exposure time
Increase drug elimination rate
Maintain hydration and blood pressure
Maintain oxygenation
Provide analgesia without affecting pups
Rapid recovery to decrease respiratory complications
Maintain airway
8. Anticipated Complications
Hypotension
Provide I.V. fluids
Keep isoflurane concentrations at a minimum
Bradycardia
Keep isoflurane at a minimum
Hypoxaemia
Provide 100% O2
Hypothermia
Bair hugger
9. Anaesthetic plan
Try to Avoid Pre-Medication but if Necessary
Acepromazine I.M.
0.01mg/kg = 0.2mg= 0.1ml
Pethidine I.M.
2mg/kg = 40 mg = 0.8mls
Pre-oxygenate 3-5 mins before induction
Surgical clip and prep whilst awake in lateral recumbency
Induction
Propofol I.V.
4mg/kg = 80mg; 10mg/ml; draw up 12ml
Fast Intubation with cuffed tube – smaller ET tube than expected
Maintenance
Bain breathing system; Isoflurane and O2 4L/min
Isoflurane MAC decreases 40% in pregnant animals
IVFT 10ml/kg/hr = 200ml/hr Hartmann’s
10. Analgesia
Midline Local Anaesthetic Block
50% Lidocaine:Bupivacaine Intradermally
4mg/kg = 80mg = 4ml
1mg/kg = 20 mg = 4ml
When Last Pup Out
Methadone 0.2-0.5mg/kg 0.4-1ml I.M.
Meloxicam 0.2mg/kg = 0.8ml S.C. – One off dose
11. Post Operative Care & Analgesia
Bitch
Keep ET tube in until fully awake to maintain airway
Methadone every 4 hours as needed for pain
1mg/kg = 20mg = 2ml S.C.
Send home on Tramadol (not licensed)
2-5mg/kg 2-3 times daily
Pups
Assess every 30 seconds
Prevent hypothermia
Provide 100% O2
Mask or ET intubation if no spontaneous breathing
12. References
Vullo, Cecilia, et al. "Anesthetic Management during Cesarean
Section in English Bulldogs." Journal of Life Sciences 8.1
(2014): 58-64.
http://www.davidpublishing.com/davidpublishing/Upfile/5/
27/2014/2014052708753330.pdf
D. Flaherty, Anaesthesia for caesarean section BVMS 4
University of Glasgow Lecture.
PREGNANT TIPS | PREGNANCY GUIDE. (n.d.). Retrieved
April 30, 2015, from http://pregnancy.pregnantshop.info/8-
week-pregnant-english-bulldog
Pricing for our English Bulldogs. (n.d.). Retrieved April 30,
2015, from
http://www.bulldozeenglishbulldogs.com/Pricing.html