Simona cavalu_ special award_Bangkok 2018

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Simona Cavalu

Cranial implant with osteointegrating structures and functional coatings

Health & Medicine

Simona cavalu_ special award_Bangkok 2018

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The aim of this study was to prepare and to characterize the structure of Al2O3–3YSZ composites with 5% TiO2 addition as well as the surface modification upon treatments with SnF2 and NaBF4, respectively. SEM micrographs showed the controlled densification of the composites as an effect of 3YSZ and TiO2 addition to alumina matrix. By FTIR and XRD, the characteristics of Al-O and Zr-O vibrations, respectively, the diffractions lines related to a-corundum and zirconia in tetragonal phase were discussed. Qualitative and quantitative results obtained by XPS and ATR FTIR demonstrated that the proposed materials are more sensitive to SnF2 than to NaBF4 treatment.

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Tempyo labelled ovalbumin at different pH values was prepared and investigated using Raman and SERS spectroscopy. Raman spectra of tempyo labelled ovalbumin in the pH range from 6.7 to 11 were compared to those of the corresponding free ovalbumin. In the basic pH range from 6.7 to 11 the molecular conformation was found to be unaffected by the tempyo presence. Adsorption versatility to the colloidal Ag particles of pure- and tempyo labelled ovalbumin was also found to be unchanged in this basic pH range. As the SERS binding site of protein the a-helix conformation is favourable.

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Simona Cavalu

Surface enhanced Raman scattering (SERS) and ATR-FTIR spectroscopy was applied in this work, in order to get information about the adsorption behavior of the title macromolecule with respect to different surfaces. In this case, the silver substrate can be considered as artificial substrate and the investigations regarding the mechanisms of adsorption can be useful in order to elucidate the active site properties of this enzyme. Our purpose is to study the adsorption mechanism of hyaluronidase onto silver nanoparticles and PMMA (polymethyl methacrylate) substrates as well as qualitative and quantitative aspects regarding perturbations of protein secondary structure (α-helix, β-sheet and unordered structures) upon adsorption, using deconvolution techniques.

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Simona Cavalu

can be doped with silver. Polymer-ceramic composites are widely applied in orthopaedics due to their biocompatibility and ability to support bone growth (osteoconductivity) and also due to bioactivity implied by self-assembling of a hydroxyapatite type layer on their surface. This in vitro study is focussed on surface microstructure changes in simulated body fluid and on antibacterial silver release from two different types of biocomposites doped with silver. SEM microscopy and ATR-FTIR spectroscopy were employed in order to evaluate the properties of the surface layer after immersion in simulated body fluid.

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Simona Cavalu

Polymer-ceramic composites based on polymethyl methacrylate are widely used in orthopaedics as suture materials and fixation devices due to their biocompatibility and ability to support bony growth (osteoconductive) and also bone bioactive (to form a calcium phosphate layer on its surface). In this study are compared the microstructure, bioactivity and biocompatibility of two different types of biocomposites: BIOLOS3®and ANTIBIOTIC SIMPLEX®. They are investigated in vitro in simulated body fluid using electrochemical measurements, SEM microscopy and ATR-FTIR spectroscopy in order to evaluate the properties of the surface layer.

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Abstract. The study was carried out to investigate the composition and type of different urinary stones upon application of extracorporeal shock wave lithotripsy. ATR FTIR spectra revealed the marker bands of a mixed stone composition containing calcium oxalate monohydrate/ calcium carbonate, respectively calcium oxalate monohydrate/cystine. The surface morphology of the samples and elemental analysis was performed by SEM-EDAX confirming the presence of oxalate, carbonate and cystine in the samples. Combination of FTIR spectroscopy and SEM-EDAX allowed quantitative and qualitative evaluation of components, the spatial distribution and the percent of major and trace elements present in a single sample.

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These are simplified slides discussing the regulation of cardiac output and venous return. Learning objectives: 1. Comprehend the determinants of cardiac output and factors affecting cardiac output 2. Comprehend the factors affecting stroke volume and heart rate and total peripheral resistance 3. Identify the factors regulating venous return 4. Discuss the causes of high and low output cardiac failure 5. Enlist the functions of veins and recognise the significance of venous reservoirs Study Resources: 1. Chapter 20, Guyton and Hall Textbook of Medical Physiology, 14th edition 2. Chapter 30 and 32, Ganong’s Review of Medical Physiology, 26th edition 3. Chapter 10, Human Physiology by Lauralee Sherwood, 9th edition 4. Physiology, Cardiac Output - StatPearls https://www.ncbi.nlm.nih.gov/books/NBK470455/

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Step into the captivating realm of cardiovascular physiology as Dr. Faiza, an esteemed Assistant Professor of Physiology, unravels the intricacies of recording an electrocardiogram (ECG). In this illuminating lecture, students are guided through the fundamental principles of ECG interpretation, from lead systems and electrode placement to the analysis of waves, segments, and intervals. Beginning with an exploration of the twelve-lead system, Dr. Faiza elucidates the significance of bipolar limb leads (I, II, III), unipolar limb leads (aVR, aVL, aVF), and unipolar chest leads (V1-V6). Through mnemonic aids and clinical anecdotes, students gain a comprehensive understanding of lead placement techniques, enabling them to navigate the complexities of ECG recording with confidence and precision. As the lecture unfolds, Dr. Faiza delves into the nuances of ECG interpretation, empowering students to correlate ECG findings with electrophysiological events in the cardiac cycle. With a focus on waveform morphology and rhythm analysis, students learn to determine heart rate, rhythm, and axis deviation, deciphering the electrocardiographic manifestations of various cardiac pathologies and physiological states. Moreover, the lecture explores the normal waves, segments, and intervals of an ECG, providing students with a detailed roadmap for interpreting these essential components. From the P wave to the T wave, students gain insight into the voltage, duration, and clinical significance of each waveform, equipping them with the skills to identify aberrations and anomalies in ECG tracings. Enriched with clinical pearls and practical tips, this lecture serves as a cornerstone for students embarking on their journey into cardiovascular medicine. By demystifying the art of ECG interpretation, Dr. Faiza empowers students to harness the power of this diagnostic tool in clinical practice, fostering a deeper appreciation for the intricate interplay between electrical activity and cardiac function.

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5-year survival of GCP after radical procedures significantly depended on: 1) PT “early-invasive cancer”; 2) PT N0--N12; 3) Cell Ratio Factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) GC cell dynamics; 9) GC characteristics; 10) tumor localization; 11) anthropometric data; 12) surgery type. Optimal diagnosis and treatment strategies for GC are: 1) screening and early detection of GC; 2) availability of sufficient quantity of experienced abdominal surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunotherapy for GCP with unfavorable prognosis.

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