cancer biology epigenetics esophageal adenocarcinoma cancer research barrett's esophagus methylation subtypes molecular subtypes fred hutch clinical research biomarkers colon cancer cancer field effects field defects methylation biomarkers colon cancer risk colon polyp risk public health genetics methylation arrays molecular ageing biological ageing epigenetic drift biomarker panel in vitro methods colon organoids organoids patient-derived xenografts pdx research genetics bwf sas tcga crc field defect biomarkers cancer biomarkers molecular subtype supervised clustering unsupervised clustering cluster subtypes gradylab
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