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MEDICAL ILLNESS OF
PREGNANCY
Salina abdulmajid manek (34)
3rd profession of BAMS.
MEDICAL ILLNESS OF
PREGNANCY
1. Hematological
disorder
2. Heart disease
3. Diabetes mellitus
4. Thyroid dysfunction
5. Jaundice
6. Viral hepatitis
7. Epilepsy
8. asthma
1. Systemic lupus
erythematosus
2. Tuberculosis
3. Syphilis
4. Parasitic
&protozoal
infestations
5. Pyelonephritis in
pregnanacy
6. Viral infection
7. HIV/AIDS
Preganacy
at high risk
High blood
pressure
Polycystic
ovary
syndrome
diabetes
Kidney
disease
Atuoimmune
disease
Recreational
disease
Obesity
HIV/AIDS
Age
First-time
pregnancy
age 35
HEMATOLOGICAL DISORDERS
ANEMIA: It is most common hematological
disorder that may occur in pregnancy, the other
being rhesisus isoimunization & blood coagultion
disorder.
Hb =11g/100ml or less ; considered as anemia.
Classification:
•Pathological
I. Deficency anemia ( iron, folic acid,vitamin
B12,protien deficency anemia)
II. Hemorrhagic ( acute: following bleeding in early
months. Chronic: hookwrom infestion, bleeding
piles.)
III. Hereditary (thalasemia, sickel cell
hemoglobinopathies, other hemoglobinopathies,
hereditary hemological anemia
IV. Bone marrow insufficient
EFFECT ON BABY
Amount of iron transferred to the fetal
is unaffected even if m other suffering
from iron deficiency anemia, then
neonatal does not suffer from anemia
at birth.
1. There is high incedence of low
birth weight babies with its
incidental hazards.
2. Intauterien death- due to severe
maternal anoxemia. The sum effect
is increased in perinatal loss.
3. Anemia in infancy due to reduced
iron store.
HEART DISEASE
 SYMPTOMS: Breathingness,
nocturnalcough, syncope, chest pain.
 SIGNS: chest murmurs, cardiac
enlargement, late systotic
 CHEST RADIPGRAPHY: cardiomegaly,
increases pulmonary vascular marking,
enlargement of pulmonary veins.
 ELECTROCARDIOGRAPH: T wave
inversion, biatrial enlargment,
dysrhythmia
 गर्भदाह- heart burn: hot water should not
be given in case of pregnancy heartbrun.
FEATAL:
 In rehumatic heart lesions, the fetal
outcome is usually good and in ni way
diffrenet from the patient without any
heart lesion.
 In cynotic group of heart lesion, there
is increased fetal loss (45%) due to
abortion, IUGP & prematarity.
 Fetal congenital cardiac disease is
increased by 3-10% if either of the
parents have congenital lesion
HIGH RISK PATIENT ARE:
I. Structure heart disease
II. Rheumatic heart disease
III. Cyanotic congenital heart disease
IV. Presence of dental &repiratory tract
infeaction
V. Prosthetic heart valve
VI. Prior history of infective endocarditis
VII. Cardic transplast
GESTATIONAL DIABETES
MELLITUS (GDM)
 Defined as carbohydrate intolerence of
variable severity with onset or first
recognition during the present pregnancy
 SCREENING: some advocate screeing
routin;ly to all pregnant mothers, others
resrve it only for the potential candidate.
a) Low risk- absence of any risk faoctors as
mentioned above ; blood glucose testing is
not routinely reqiured.
b) Average risk- some risk factors;prefrom
screening test
c) High risk-blood glucose test as soon as
feasiable
FETAL & NEO NATAL
 Fetal macrosomia (40-50%) with birth weight
>4kg probably result; a.)maternal
hypergycemia , b.) Elevation of maternal free
fatty acid (FFA) in diabetes leads to its
increased transfer to the fetus; accleration of
triglyceride synthesis; adiopsity
 Congenital malformation
 Neural tube defeact
 Double uteres
 Polycystic kidney
 Anorectal atresia
 Sngel umbilical artery
THYRIOD DYSFUNTION
 HYPERTHYROIDISM
 MATERNAL: miscarriage, pretrem delivery,
pre eclapsia, congestive cardiac failure,
placnetal abruption, thyroid strom infection.
 Fetal/neonatal: LBW, FGR, prematirity,
stillbirth, hyperthyriodisum, increased
perinatal morbidty & mortality.
 HYPOTHYROIDISM
 MATERNAL: myxedema rarely presence in
pregnancy because they tend to be infertiel.
 FETAL/NEONETAL: hihg fetal wastage in
from of abortion, stillbirth and prrmaturity and
deficient intellectual development of the child.
JAUNDICE
 When the serum bilirubin level exceed 2mg%,
visible yellow staining of the tissue appear.
•AYURVED : गर्र्भणी अतिसार
•का.सं.खि 20
•Treatment :nuse of pippali and root of
ankotha mixed with juice of hourse milk
is benificial. Decocotion of prsni parini,
bala & vasa should be prescribed.
HYPERTENSION IN
PREGANNACY
•Hypertension is one of common medical complication of pregnancy
and contributes significantly to maternal and perinatal morbidity and
mortality
•Maternal DBP>110 is associated With high risk of
placental abruption and fetal growth restriction
•Superimposed preeclampsia cause most of the
morbidity.
•4 categories
1. Chronic hypertension
2. Pregnancy induced hypertension
3. Preeclampsia eclampsia
4. Preeclampsia superimposed on chronic HTN
Hypertensive disorder of
pregnancy
Pregnant woman with
blood pressure highrt than
140/90 mmHg
Before 20 week of
gestation
No or stable protein uria
Chronic hypertension
New or increased
proteinuria, development
of increase blood
pressure, or hellp
syndrome
Preeclampsia
superimposed on chronic
hypertension
After 20 week of gestation
Proteinuria
preeclampsia
No proteinuria
Gestation hypertension
PRE- ECLAMPSIA (PE)
Definition:
It is a multisystem disorder of unknown etiology characterized by
development of hypertension to the extended of 140/90mmHg or more with
proteinuria after the 20th week in a previously normotensive and
nonproteninuric woman.
Diagnostic creteria:
An absolute rise of blood pressure of at least 140/90mmHg, if
previous blood pressure is not known or rise in systolic pressure of at least
30mmHg, or rise in diastolic pressure of at least 15mmHg over the
previously known blood pressure is called pregnancy-induced
hypertention.
• A rise of 20 mmHg MAP (mean arterial pressure) over the pervious
reading, or when the MAP IS 105mm/Hg or more should be considered as
significant.
•EDEMA: demonstration of pitting edema over the ankels after 12 hours
bed rest or excessive gain in wegiht of more than 4Ib(1.814 kg) a week in
the later months of pregnancy may be the earliest evidence of pre-
eclamsia
GESTATIONAL
HYPERTENSION
A sustained rise of blood pressure to 140/90mmHg or more at least
two occasions 4 or more hours apart beyond the 20th week of
preganancy or within the first 48 hours of delivery in perviously
normotensive woman is called gestational hyperytension.
IT should filfill the folloeing criteria:
1) Absence of any evidence for the underlying cause of
hypertension
2) Genrally unassociated with other evidence of preeclampsia
3) Majority of cases are more tham or equal to 37 weeks
pregnancy
4) Genrally not associated with hemoconcentration or
thromnocytopenia, raised serum uric acid level or hepatic
dysfunction.
5) The blood pressure should come down to normal within 12 week
folloeing delivery
HYPERTENTION IN
PREGANANCY IS USUALLY
CAUSED BY:
•Preclamsia
•Maternal age more than 35 years or less than 15 years
•Obesity
•Angiotensin gene-235
•Antiphospholiod antibody
•Multiple gestation
EFECT ON FETUS:
Gestational hypertension can also lead to fetal problems including
intrauterine growth restriction (poor fetal growth) and stillbirth.
If untreated, severe gestational hypertension may cause dangerous seizures
(eclampsia) and even death in the mother and fetus. Because of these risks, it
may be necessary for the baby to be delivered early, before 37 weeks
gestation.
SYMPTOMS:
 Increased blood pressure
 Absence or presence of protein in the urine
(to diagnose gestational hypertension or
preeclampsia)
 Edema (swelling)
 Sudden weight gain
 Visual changes such as blurred or double
vision
 Nausea, vomiting
 Right-sided upper abdominal pain or pain
around the stomach
 Urinating small amounts
 Changes in liver or kidney function tests
REFRENCES
 DC DUTTA’S TEXTBOOK OF
OBSTERTRIC
 CHAPTER 20- MEDICAL & SURGICAL
ILLNESS COMPLOCATING
PREGNANCY
 CHAPTER 18- HYPERTENSIVE
DISORDER IN PREGNANCY
 REFRED FROM PRESENTION BY Dr.
MOHAMMAD LIYAS, Dr.MANAVITA
 GATE RESEARCH BY Dr. TRITH
BHATTA
 PRASUTITANTRA EVUM STRI ROG –
P.V TIVARI

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Medical illness of pregnancy

  • 1. MEDICAL ILLNESS OF PREGNANCY Salina abdulmajid manek (34) 3rd profession of BAMS.
  • 2. MEDICAL ILLNESS OF PREGNANCY 1. Hematological disorder 2. Heart disease 3. Diabetes mellitus 4. Thyroid dysfunction 5. Jaundice 6. Viral hepatitis 7. Epilepsy 8. asthma 1. Systemic lupus erythematosus 2. Tuberculosis 3. Syphilis 4. Parasitic &protozoal infestations 5. Pyelonephritis in pregnanacy 6. Viral infection 7. HIV/AIDS
  • 3. Preganacy at high risk High blood pressure Polycystic ovary syndrome diabetes Kidney disease Atuoimmune disease Recreational disease Obesity HIV/AIDS Age First-time pregnancy age 35
  • 4. HEMATOLOGICAL DISORDERS ANEMIA: It is most common hematological disorder that may occur in pregnancy, the other being rhesisus isoimunization & blood coagultion disorder. Hb =11g/100ml or less ; considered as anemia. Classification: •Pathological I. Deficency anemia ( iron, folic acid,vitamin B12,protien deficency anemia) II. Hemorrhagic ( acute: following bleeding in early months. Chronic: hookwrom infestion, bleeding piles.) III. Hereditary (thalasemia, sickel cell hemoglobinopathies, other hemoglobinopathies, hereditary hemological anemia IV. Bone marrow insufficient
  • 5. EFFECT ON BABY Amount of iron transferred to the fetal is unaffected even if m other suffering from iron deficiency anemia, then neonatal does not suffer from anemia at birth. 1. There is high incedence of low birth weight babies with its incidental hazards. 2. Intauterien death- due to severe maternal anoxemia. The sum effect is increased in perinatal loss. 3. Anemia in infancy due to reduced iron store.
  • 6. HEART DISEASE  SYMPTOMS: Breathingness, nocturnalcough, syncope, chest pain.  SIGNS: chest murmurs, cardiac enlargement, late systotic  CHEST RADIPGRAPHY: cardiomegaly, increases pulmonary vascular marking, enlargement of pulmonary veins.  ELECTROCARDIOGRAPH: T wave inversion, biatrial enlargment, dysrhythmia  गर्भदाह- heart burn: hot water should not be given in case of pregnancy heartbrun.
  • 7. FEATAL:  In rehumatic heart lesions, the fetal outcome is usually good and in ni way diffrenet from the patient without any heart lesion.  In cynotic group of heart lesion, there is increased fetal loss (45%) due to abortion, IUGP & prematarity.  Fetal congenital cardiac disease is increased by 3-10% if either of the parents have congenital lesion
  • 8. HIGH RISK PATIENT ARE: I. Structure heart disease II. Rheumatic heart disease III. Cyanotic congenital heart disease IV. Presence of dental &repiratory tract infeaction V. Prosthetic heart valve VI. Prior history of infective endocarditis VII. Cardic transplast
  • 9. GESTATIONAL DIABETES MELLITUS (GDM)  Defined as carbohydrate intolerence of variable severity with onset or first recognition during the present pregnancy  SCREENING: some advocate screeing routin;ly to all pregnant mothers, others resrve it only for the potential candidate. a) Low risk- absence of any risk faoctors as mentioned above ; blood glucose testing is not routinely reqiured. b) Average risk- some risk factors;prefrom screening test c) High risk-blood glucose test as soon as feasiable
  • 10. FETAL & NEO NATAL  Fetal macrosomia (40-50%) with birth weight >4kg probably result; a.)maternal hypergycemia , b.) Elevation of maternal free fatty acid (FFA) in diabetes leads to its increased transfer to the fetus; accleration of triglyceride synthesis; adiopsity  Congenital malformation  Neural tube defeact  Double uteres  Polycystic kidney  Anorectal atresia  Sngel umbilical artery
  • 11. THYRIOD DYSFUNTION  HYPERTHYROIDISM  MATERNAL: miscarriage, pretrem delivery, pre eclapsia, congestive cardiac failure, placnetal abruption, thyroid strom infection.  Fetal/neonatal: LBW, FGR, prematirity, stillbirth, hyperthyriodisum, increased perinatal morbidty & mortality.  HYPOTHYROIDISM  MATERNAL: myxedema rarely presence in pregnancy because they tend to be infertiel.  FETAL/NEONETAL: hihg fetal wastage in from of abortion, stillbirth and prrmaturity and deficient intellectual development of the child.
  • 12. JAUNDICE  When the serum bilirubin level exceed 2mg%, visible yellow staining of the tissue appear. •AYURVED : गर्र्भणी अतिसार •का.सं.खि 20 •Treatment :nuse of pippali and root of ankotha mixed with juice of hourse milk is benificial. Decocotion of prsni parini, bala & vasa should be prescribed.
  • 13. HYPERTENSION IN PREGANNACY •Hypertension is one of common medical complication of pregnancy and contributes significantly to maternal and perinatal morbidity and mortality •Maternal DBP>110 is associated With high risk of placental abruption and fetal growth restriction •Superimposed preeclampsia cause most of the morbidity. •4 categories 1. Chronic hypertension 2. Pregnancy induced hypertension 3. Preeclampsia eclampsia 4. Preeclampsia superimposed on chronic HTN
  • 14. Hypertensive disorder of pregnancy Pregnant woman with blood pressure highrt than 140/90 mmHg Before 20 week of gestation No or stable protein uria Chronic hypertension New or increased proteinuria, development of increase blood pressure, or hellp syndrome Preeclampsia superimposed on chronic hypertension After 20 week of gestation Proteinuria preeclampsia No proteinuria Gestation hypertension
  • 15. PRE- ECLAMPSIA (PE) Definition: It is a multisystem disorder of unknown etiology characterized by development of hypertension to the extended of 140/90mmHg or more with proteinuria after the 20th week in a previously normotensive and nonproteninuric woman. Diagnostic creteria: An absolute rise of blood pressure of at least 140/90mmHg, if previous blood pressure is not known or rise in systolic pressure of at least 30mmHg, or rise in diastolic pressure of at least 15mmHg over the previously known blood pressure is called pregnancy-induced hypertention. • A rise of 20 mmHg MAP (mean arterial pressure) over the pervious reading, or when the MAP IS 105mm/Hg or more should be considered as significant. •EDEMA: demonstration of pitting edema over the ankels after 12 hours bed rest or excessive gain in wegiht of more than 4Ib(1.814 kg) a week in the later months of pregnancy may be the earliest evidence of pre- eclamsia
  • 16. GESTATIONAL HYPERTENSION A sustained rise of blood pressure to 140/90mmHg or more at least two occasions 4 or more hours apart beyond the 20th week of preganancy or within the first 48 hours of delivery in perviously normotensive woman is called gestational hyperytension. IT should filfill the folloeing criteria: 1) Absence of any evidence for the underlying cause of hypertension 2) Genrally unassociated with other evidence of preeclampsia 3) Majority of cases are more tham or equal to 37 weeks pregnancy 4) Genrally not associated with hemoconcentration or thromnocytopenia, raised serum uric acid level or hepatic dysfunction. 5) The blood pressure should come down to normal within 12 week folloeing delivery
  • 17. HYPERTENTION IN PREGANANCY IS USUALLY CAUSED BY: •Preclamsia •Maternal age more than 35 years or less than 15 years •Obesity •Angiotensin gene-235 •Antiphospholiod antibody •Multiple gestation EFECT ON FETUS: Gestational hypertension can also lead to fetal problems including intrauterine growth restriction (poor fetal growth) and stillbirth. If untreated, severe gestational hypertension may cause dangerous seizures (eclampsia) and even death in the mother and fetus. Because of these risks, it may be necessary for the baby to be delivered early, before 37 weeks gestation.
  • 18. SYMPTOMS:  Increased blood pressure  Absence or presence of protein in the urine (to diagnose gestational hypertension or preeclampsia)  Edema (swelling)  Sudden weight gain  Visual changes such as blurred or double vision  Nausea, vomiting  Right-sided upper abdominal pain or pain around the stomach  Urinating small amounts  Changes in liver or kidney function tests
  • 19. REFRENCES  DC DUTTA’S TEXTBOOK OF OBSTERTRIC  CHAPTER 20- MEDICAL & SURGICAL ILLNESS COMPLOCATING PREGNANCY  CHAPTER 18- HYPERTENSIVE DISORDER IN PREGNANCY  REFRED FROM PRESENTION BY Dr. MOHAMMAD LIYAS, Dr.MANAVITA  GATE RESEARCH BY Dr. TRITH BHATTA  PRASUTITANTRA EVUM STRI ROG – P.V TIVARI