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Presentation  of Doctoral Research
             Rupert Booth
             May 17th 2011

Warwick Business School
Contents
      Research context, references and questions
      Five sets of hypotheses
      Methodology and enablers
      Research findings
      Contributions to literatures
      Publication plans
      Future work 


Warwick Business School
Research context
    Four decades of research into Post‐Acquisition 
     Performance (PAP) and the ‘Merger Paradox’
    Currently PAP recognised as an intellectual construct, 
     related to intention and perspective
    Several independent literatures (e.g. finance, organisational 
     behaviour, finance) but this research opts for:
     strategic management
     comparative efficiency
    Pharmaceutical sector offers clarity of process and 
     availability of data
Warwick Business School
Research questions
      Merger paradox – the continued popularity of M&A 
       despite lack of success– i.e. motive
      ‘Success’ in what way , i.e. measurement (adopt neo‐
       positivist philosophical basis)
      ‘Success’ for whom and when, e.g.
        the Firm now
        future Firm
        the Sector
      How to select measures for a Performance 
       Measurement Framework (PMF)
      Scale effects in R&D, as distinct from M&A
Warwick Business School
Five sets of hypotheses
      Set 1: Returns to scale
      Sets 2 to 5
        Firm’s M&A History and R&D Efficiency
        M&A History and Financial History
        M&A History & R&D History (Sectoral)
        M&A History and Sales over Assets
      Sets 2 to 5 all consider
        M&A in aggregate
        Cross‐border
        Cross‐product

Warwick Business School
Methodology and ‘Enablers’
      Develop approach to design  of PMF: Design Principles
      Apply to pharmaceutical firm and key competitive process: R&D
      Identify most appropriate process efficiency technique: DEA
      Collect R&D data and analyse efficiency:
        Constant or variable returns to scale
        Various  inputs (e.g. include staff or not)
        Various outputs (e.g. compounds or trials)
      Develop merger typology and scale metrics
      Populate typology with M&A data for major firms for full wave
      Undertake hypothesis testing

Warwick Business School
Enabler 1: Choice of sector/process:
Pharmaceutical R&D




Warwick Business School
Enabler 2: Resource Based View
     Major strand of strategic           Phase          Author                   Contribution to Measurement

      management theory
     Focuses on differences between     Early      Wernerfelt (1984)      Resources are the differentiating factors

      firms and how these ‘resources’               Rumelt (1984)          Isolating mechanisms with examples
      are valuable
     To date, measurement has not       Consolid   Barney (1991)          VRIN tests: Valuable Rare Imperfectly imitable
      been a priority                    ation                             Non-substitutable
                                                    Peteraf (1993)         Link to value and rent generation
     Useful theoretical basis for 
      identification of parameters to    Dynamic    Dierickx and Cool
                                                    (1989)
                                                                           Importance of deployment as opposed to
                                                                           possession (prelude to process)
      be measures from outside the 
      firm                                          Amit              &    Capabilities (recognition of intangible aspect to
                                                    Schoemaker             resources)
     Avoids tendency to ‘measure                   (1993)

      what is available’                            Teece
                                                    (1997)
                                                             et      al.   Paths, Positions and Processes


     Provides basis for measuring       Reasses    Peteraf & Barney       Efficiency perspective
                                         sment      (2003)
      long‐term competitiveness

    Warwick Business School
Enabler 3: Data Envelopment Analysis
      Simple efficiency analysis considers        Graphical two‐dimensional example:
       ratio of output to input
      Many processes have multiple inputs 
       and outputs
      Data Envelopment Analysis (DEA) is a 
       method to measure comparative 
       efficiency of ‘decision making units’
      Does not require knowledge of 
       ‘production function’ relating inputs 
       to outputs
      Natural choice for application:
           Multiple inputs and outputs
           R&D has no known production function




Warwick Business School
Application of DEA
         Range of Models                          Use of Results
 Scale: CRS or VRS                     DEA results cannot be used in 
 Choice of outputs:  compounds or 
                                         statistical tests as they are not 
  trials                                 independent observations
 Choice  of inputs:                    Therefore use results to bisect the 
                                         sample (n=48) into two groups of 
     ○ Expenditure (primary)
                                         above‐median and below‐median 
     ○ Staff (affected by M&A)
                                         efficiency
 Relative weight restrictions
                                        Use statistical tests to examine 
   Outputs (pipeline stages)            differences in Measure of Central 
   Inputs (R&D expenses versus staff)   Tendency between groups
                                        Parametric tests for mean and 
                                         non‐parametric tests for median



Warwick Business School
Enabler 4: Merger History
                          Principles         Results
 Ten year period covers entire   Threshold set at £100m
  merger wave and an              Total number deals =  591
  economic cycle
                                  140 deals related to Top 48:
 Analyse all deals above 
                                    64 cross‐border
  threshold in relevant             29 cross‐sector
  industrial code of acquirer
      Relate deals back to top 48 
       ‘survivors’
      Use industrial code to 
       identify cross‐border and 
       cross‐product deals
Warwick Business School
Summary of hypothesis testing
      Set 1:
        Constant returns to scale refuted
        Relationship established between scale efficiency and size
      Set 2:
        In aggregate, no association between merger history and technical efficiency
      Set 3:
        In aggregate, positive association between merger history and financial 
            efficiency 
      Set 4:
        For the sector as a whole, positive association between sum of deals and 
            technically efficient companies
      Set 5:
        For cross‐sector deals, new example of biased financial metric
      Further conclusions for cross‐border and cross‐sector in Sets 2 to 4
Warwick Business School
Research contribution #1
The Paradoxes of Mergers: The Effect of Alternative Measures of Post‐
    Acquisition Performance:
      Elaboration on ‘different motive’ hypothesis
      Measures themselves provide divergent interpretations of ‘success’
      Financial measures suggest merger ‘success’ providing both ex ante 
       justification and ex post ability to continue
      At any a moment in time, merger‐prone companies appear to be more 
       efficient, technically and financially
      However, technical measures suggest no improvement of efficiency




Warwick Business School
Research contribution #2
 Application of the Resource Based View to Performance Measurement 
    Framework Design for use with Data Envelopment Analysis:
Category              No.   Principle                                                                                           Ref
Scope and Structure
Stakeholders          1     Recognise major stakeholders of the firm (e.g. the firm’s owner and customers).                     (i)
Leading measures      2     Include at least one leading measure (typically non-financial).                                     (ii)
Risk                  3     Risk exposure should be measured.                                                                   (iv)
Resources and Barriers
Differences           4     The PMF should measure key resources: the crucial few factors that differentiate the firm.          (a)
VRIN                  5     Measures should be on how resources are VRIN.                                                       (c)
Link to value         6     Measures should consider how resources are linked to value creation or economic rent.               (d)
Intangibles           7     Capabilities, or intangible resources, should be measured where possible.                           (f)
Barriers              8     Barriers to imitation that affect the value of a resource should be measured.                       (b)
Processes and Positions
Deployment            9     Deployment of resources, through processes, should be measured.                                     (e)
Dynamic links         10    Causal links between measures should be identified to provide a time dimension.                     (iii)
Static positions      11    Static positions are candidates for measurement.                                                    (g)
Efficiency and Benchmarking
Benchmarking          12    Efficiency should be measured, after recognising previous paths of development, for benchmarking.   (h)


Warwick Business School
Research contribution  #3
Use of Data Envelopment Analysis to Establish Scale Efficiency Factor in Pharmaceutical 
    R&D:


                              Most comprehensive application of DEA to R&D to date
                              Conclusive results on pharmaceutical R&D scale effects


                          0
                               3    4    5        6          7   8   9
                        ‐0.5
ln (Scale Efficiency)




                         ‐1

                        ‐1.5

                         ‐2

                        ‐2.5

                         ‐3
                                             ln (mean R&D)




Warwick Business School
Research contribution #4
                  The Distribution of Size and Frequency of M&A Deals in the 
                   pharmaceutical sector:

                                   Distribution of Deal Value

            1000




            100
No. Deals




                                                                                 y = 182.71e-0.3888x
                                                                                    R2 = 0.9042

             10




              1
                   1   2   3   4   5     6    7   8      9   10   11   12   13
                                       Ln (Deal Value)




Warwick Business School
Future work
      Select different periods of analysis to test time‐invariance of 
       conclusions
      Monte Carlo simulation to test robustness of conclusions to 
       research serendipity
      Use observed statistical distributions to increase power of 
       statistics test, e.g. Poisson regression
      Apply DEA to other sectors with readily identifiable R&D 
       inputs and outputs
      Apply Design Principles to design performance measurement 
       frameworks on other sectors
      Repeat M&A analysis in other sectors
Warwick Business School

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Viva 17 May

  • 1. Presentation  of Doctoral Research Rupert Booth May 17th 2011 Warwick Business School
  • 2. Contents  Research context, references and questions  Five sets of hypotheses  Methodology and enablers  Research findings  Contributions to literatures  Publication plans  Future work  Warwick Business School
  • 3. Research context  Four decades of research into Post‐Acquisition  Performance (PAP) and the ‘Merger Paradox’  Currently PAP recognised as an intellectual construct,  related to intention and perspective  Several independent literatures (e.g. finance, organisational  behaviour, finance) but this research opts for:  strategic management  comparative efficiency  Pharmaceutical sector offers clarity of process and  availability of data Warwick Business School
  • 4. Research questions  Merger paradox – the continued popularity of M&A  despite lack of success– i.e. motive  ‘Success’ in what way , i.e. measurement (adopt neo‐ positivist philosophical basis)  ‘Success’ for whom and when, e.g.  the Firm now  future Firm  the Sector  How to select measures for a Performance  Measurement Framework (PMF)  Scale effects in R&D, as distinct from M&A Warwick Business School
  • 5. Five sets of hypotheses  Set 1: Returns to scale  Sets 2 to 5  Firm’s M&A History and R&D Efficiency  M&A History and Financial History  M&A History & R&D History (Sectoral)  M&A History and Sales over Assets  Sets 2 to 5 all consider  M&A in aggregate  Cross‐border  Cross‐product Warwick Business School
  • 6. Methodology and ‘Enablers’  Develop approach to design  of PMF: Design Principles  Apply to pharmaceutical firm and key competitive process: R&D  Identify most appropriate process efficiency technique: DEA  Collect R&D data and analyse efficiency:  Constant or variable returns to scale  Various  inputs (e.g. include staff or not)  Various outputs (e.g. compounds or trials)  Develop merger typology and scale metrics  Populate typology with M&A data for major firms for full wave  Undertake hypothesis testing Warwick Business School
  • 8. Enabler 2: Resource Based View  Major strand of strategic  Phase Author Contribution to Measurement management theory  Focuses on differences between  Early Wernerfelt (1984) Resources are the differentiating factors firms and how these ‘resources’  Rumelt (1984) Isolating mechanisms with examples are valuable  To date, measurement has not  Consolid Barney (1991) VRIN tests: Valuable Rare Imperfectly imitable been a priority ation Non-substitutable Peteraf (1993) Link to value and rent generation  Useful theoretical basis for  identification of parameters to  Dynamic Dierickx and Cool (1989) Importance of deployment as opposed to possession (prelude to process) be measures from outside the  firm Amit & Capabilities (recognition of intangible aspect to Schoemaker resources)  Avoids tendency to ‘measure  (1993) what is available’ Teece (1997) et al. Paths, Positions and Processes  Provides basis for measuring  Reasses Peteraf & Barney Efficiency perspective sment (2003) long‐term competitiveness Warwick Business School
  • 9. Enabler 3: Data Envelopment Analysis  Simple efficiency analysis considers  Graphical two‐dimensional example: ratio of output to input  Many processes have multiple inputs  and outputs  Data Envelopment Analysis (DEA) is a  method to measure comparative  efficiency of ‘decision making units’  Does not require knowledge of  ‘production function’ relating inputs  to outputs  Natural choice for application:  Multiple inputs and outputs  R&D has no known production function Warwick Business School
  • 10. Application of DEA Range of Models Use of Results  Scale: CRS or VRS  DEA results cannot be used in   Choice of outputs:  compounds or  statistical tests as they are not  trials independent observations  Choice  of inputs:  Therefore use results to bisect the  sample (n=48) into two groups of  ○ Expenditure (primary) above‐median and below‐median  ○ Staff (affected by M&A) efficiency  Relative weight restrictions  Use statistical tests to examine   Outputs (pipeline stages) differences in Measure of Central   Inputs (R&D expenses versus staff) Tendency between groups  Parametric tests for mean and  non‐parametric tests for median Warwick Business School
  • 11. Enabler 4: Merger History Principles Results  Ten year period covers entire   Threshold set at £100m merger wave and an   Total number deals =  591 economic cycle  140 deals related to Top 48:  Analyse all deals above   64 cross‐border threshold in relevant   29 cross‐sector industrial code of acquirer  Relate deals back to top 48  ‘survivors’  Use industrial code to  identify cross‐border and  cross‐product deals Warwick Business School
  • 12. Summary of hypothesis testing  Set 1:  Constant returns to scale refuted  Relationship established between scale efficiency and size  Set 2:  In aggregate, no association between merger history and technical efficiency  Set 3:  In aggregate, positive association between merger history and financial  efficiency   Set 4:  For the sector as a whole, positive association between sum of deals and  technically efficient companies  Set 5:  For cross‐sector deals, new example of biased financial metric  Further conclusions for cross‐border and cross‐sector in Sets 2 to 4 Warwick Business School
  • 13. Research contribution #1 The Paradoxes of Mergers: The Effect of Alternative Measures of Post‐ Acquisition Performance:  Elaboration on ‘different motive’ hypothesis  Measures themselves provide divergent interpretations of ‘success’  Financial measures suggest merger ‘success’ providing both ex ante  justification and ex post ability to continue  At any a moment in time, merger‐prone companies appear to be more  efficient, technically and financially  However, technical measures suggest no improvement of efficiency Warwick Business School
  • 14. Research contribution #2 Application of the Resource Based View to Performance Measurement  Framework Design for use with Data Envelopment Analysis: Category No. Principle Ref Scope and Structure Stakeholders 1 Recognise major stakeholders of the firm (e.g. the firm’s owner and customers). (i) Leading measures 2 Include at least one leading measure (typically non-financial). (ii) Risk 3 Risk exposure should be measured. (iv) Resources and Barriers Differences 4 The PMF should measure key resources: the crucial few factors that differentiate the firm. (a) VRIN 5 Measures should be on how resources are VRIN. (c) Link to value 6 Measures should consider how resources are linked to value creation or economic rent. (d) Intangibles 7 Capabilities, or intangible resources, should be measured where possible. (f) Barriers 8 Barriers to imitation that affect the value of a resource should be measured. (b) Processes and Positions Deployment 9 Deployment of resources, through processes, should be measured. (e) Dynamic links 10 Causal links between measures should be identified to provide a time dimension. (iii) Static positions 11 Static positions are candidates for measurement. (g) Efficiency and Benchmarking Benchmarking 12 Efficiency should be measured, after recognising previous paths of development, for benchmarking. (h) Warwick Business School
  • 15. Research contribution  #3 Use of Data Envelopment Analysis to Establish Scale Efficiency Factor in Pharmaceutical  R&D:  Most comprehensive application of DEA to R&D to date  Conclusive results on pharmaceutical R&D scale effects 0 3 4 5 6 7 8 9 ‐0.5 ln (Scale Efficiency) ‐1 ‐1.5 ‐2 ‐2.5 ‐3 ln (mean R&D) Warwick Business School
  • 16. Research contribution #4  The Distribution of Size and Frequency of M&A Deals in the  pharmaceutical sector: Distribution of Deal Value 1000 100 No. Deals y = 182.71e-0.3888x R2 = 0.9042 10 1 1 2 3 4 5 6 7 8 9 10 11 12 13 Ln (Deal Value) Warwick Business School
  • 17. Future work  Select different periods of analysis to test time‐invariance of  conclusions  Monte Carlo simulation to test robustness of conclusions to  research serendipity  Use observed statistical distributions to increase power of  statistics test, e.g. Poisson regression  Apply DEA to other sectors with readily identifiable R&D  inputs and outputs  Apply Design Principles to design performance measurement  frameworks on other sectors  Repeat M&A analysis in other sectors Warwick Business School