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Arrhythmias and Clinical EP
A443
JACC March 17, 2015
Volume 65, Issue 10S
The Profile of Survivors of Community Pediatric Sudden Cardiac Arrest
Poster Contributions
Poster Hall B1
Sunday, March 15, 2015, 3:45 p.m.-4:30 p.m.
Session Title: Novel Findings in the World of Electrophysiology
Abstract Category: 7. Arrhythmias and Clinical EP: Other
Presentation Number: 1220-268
Authors: Barry A. Love, Robert Tozzi, Ira Parness, Shubhika Srivastava, James Nielsen, Davendra Mehta, Srinivas Dukkipati, Mount Sinai
Medical Center, New York, NY, USA
Background: Sudden cardiac arrest (SCA) in an apparently healthy child is a rare event with a reported incidence of ~3.5/100,000/
yr. In the past, death or severe neurologic injury after SCA was common. However with the increasing prevalence of automatic external
defibrillators in the community, survival with good neurologic outcomes may be improving.
Methods: We reviewed our single center experience of previously healthy children < 21 yrs who were cared for after resuscitated cardiac
arrest in the community between Jan 2003 and September 2014. Patients had step-wise evaluation with ECG, echocardiogram, cardiac
MRI, and genetic testing. Additional testing including stress test, prolonged ECG monitoring, electrophysiology testing and cardiac
catheterization was undertaken as necessary to determine the underlying diagnosis.
Results: We identified 28 patients who were resuscitated - 9 (32%) by lay rescuers and the remainder by trained personnel. The
median age was 15 yrs (0.5-20). The most common diagnoses were channelopathy in 9 (21%), hypertrophic cardiomyopathy in 6 (21%),
structural heart issues in 5(18%) and WPW in 2 (7%). Despite complete evaluation, the diagnosis remains unknown in 6 (21%). Twenty-
six patients (93%) made an excellent neurologic recovery. Twenty-six had an ICD implanted and 25 are taking beta blockers and/or
other antiarrhythmic medication. Patients have been followed for a mean of 4.6 years (2mo-12yrs) and 14 patients have had subsequent
appropriate life-saving ICD therapies. One patient with CPVT who refused ICD replacement at battery depletion died in follow-up.
Conclusion: The prognosis for pediatric patients who are resuscitated from SCA is optimistic. A definitive diagnosis can be made in most
patients. ICDs combined with medical therapy provides excellent protection against secondary events.
Downloaded From: http://content.onlinejacc.org/ by Robert Tozzi on 05/26/2015

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Tozzi-ACC.15

  • 1. Arrhythmias and Clinical EP A443 JACC March 17, 2015 Volume 65, Issue 10S The Profile of Survivors of Community Pediatric Sudden Cardiac Arrest Poster Contributions Poster Hall B1 Sunday, March 15, 2015, 3:45 p.m.-4:30 p.m. Session Title: Novel Findings in the World of Electrophysiology Abstract Category: 7. Arrhythmias and Clinical EP: Other Presentation Number: 1220-268 Authors: Barry A. Love, Robert Tozzi, Ira Parness, Shubhika Srivastava, James Nielsen, Davendra Mehta, Srinivas Dukkipati, Mount Sinai Medical Center, New York, NY, USA Background: Sudden cardiac arrest (SCA) in an apparently healthy child is a rare event with a reported incidence of ~3.5/100,000/ yr. In the past, death or severe neurologic injury after SCA was common. However with the increasing prevalence of automatic external defibrillators in the community, survival with good neurologic outcomes may be improving. Methods: We reviewed our single center experience of previously healthy children < 21 yrs who were cared for after resuscitated cardiac arrest in the community between Jan 2003 and September 2014. Patients had step-wise evaluation with ECG, echocardiogram, cardiac MRI, and genetic testing. Additional testing including stress test, prolonged ECG monitoring, electrophysiology testing and cardiac catheterization was undertaken as necessary to determine the underlying diagnosis. Results: We identified 28 patients who were resuscitated - 9 (32%) by lay rescuers and the remainder by trained personnel. The median age was 15 yrs (0.5-20). The most common diagnoses were channelopathy in 9 (21%), hypertrophic cardiomyopathy in 6 (21%), structural heart issues in 5(18%) and WPW in 2 (7%). Despite complete evaluation, the diagnosis remains unknown in 6 (21%). Twenty- six patients (93%) made an excellent neurologic recovery. Twenty-six had an ICD implanted and 25 are taking beta blockers and/or other antiarrhythmic medication. Patients have been followed for a mean of 4.6 years (2mo-12yrs) and 14 patients have had subsequent appropriate life-saving ICD therapies. One patient with CPVT who refused ICD replacement at battery depletion died in follow-up. Conclusion: The prognosis for pediatric patients who are resuscitated from SCA is optimistic. A definitive diagnosis can be made in most patients. ICDs combined with medical therapy provides excellent protection against secondary events. Downloaded From: http://content.onlinejacc.org/ by Robert Tozzi on 05/26/2015