This study reviewed 28 pediatric patients under the age of 21 who suffered sudden cardiac arrest in the community but were resuscitated between 2003 and 2014. The most common diagnoses were channelopathies in 9 patients (21%), hypertrophic cardiomyopathy in 6 patients (21%), and structural heart issues in 5 patients (18%). A definitive diagnosis could not be determined in 6 patients (21%). Despite complete evaluation, 26 patients (93%) had an excellent neurologic recovery. All 26 patients received an implantable cardioverter-defibrillator and 25 were prescribed beta blockers and/or other antiarrhythmic medications. With a mean follow up of 4.6 years, 14 patients received appropriate life-saving shocks from their I
Unanswered questions in thrombolytic therapy for acute ischemic stroke. 2013
Tozzi-ACC.15
1. Arrhythmias and Clinical EP
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JACC March 17, 2015
Volume 65, Issue 10S
The Profile of Survivors of Community Pediatric Sudden Cardiac Arrest
Poster Contributions
Poster Hall B1
Sunday, March 15, 2015, 3:45 p.m.-4:30 p.m.
Session Title: Novel Findings in the World of Electrophysiology
Abstract Category: 7. Arrhythmias and Clinical EP: Other
Presentation Number: 1220-268
Authors: Barry A. Love, Robert Tozzi, Ira Parness, Shubhika Srivastava, James Nielsen, Davendra Mehta, Srinivas Dukkipati, Mount Sinai
Medical Center, New York, NY, USA
Background: Sudden cardiac arrest (SCA) in an apparently healthy child is a rare event with a reported incidence of ~3.5/100,000/
yr. In the past, death or severe neurologic injury after SCA was common. However with the increasing prevalence of automatic external
defibrillators in the community, survival with good neurologic outcomes may be improving.
Methods: We reviewed our single center experience of previously healthy children < 21 yrs who were cared for after resuscitated cardiac
arrest in the community between Jan 2003 and September 2014. Patients had step-wise evaluation with ECG, echocardiogram, cardiac
MRI, and genetic testing. Additional testing including stress test, prolonged ECG monitoring, electrophysiology testing and cardiac
catheterization was undertaken as necessary to determine the underlying diagnosis.
Results: We identified 28 patients who were resuscitated - 9 (32%) by lay rescuers and the remainder by trained personnel. The
median age was 15 yrs (0.5-20). The most common diagnoses were channelopathy in 9 (21%), hypertrophic cardiomyopathy in 6 (21%),
structural heart issues in 5(18%) and WPW in 2 (7%). Despite complete evaluation, the diagnosis remains unknown in 6 (21%). Twenty-
six patients (93%) made an excellent neurologic recovery. Twenty-six had an ICD implanted and 25 are taking beta blockers and/or
other antiarrhythmic medication. Patients have been followed for a mean of 4.6 years (2mo-12yrs) and 14 patients have had subsequent
appropriate life-saving ICD therapies. One patient with CPVT who refused ICD replacement at battery depletion died in follow-up.
Conclusion: The prognosis for pediatric patients who are resuscitated from SCA is optimistic. A definitive diagnosis can be made in most
patients. ICDs combined with medical therapy provides excellent protection against secondary events.
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