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Rebecca Cowan, PhD, LPC, NCC
Eastern Virginia Medical School
Department of Family & Community
Medicine
Transitioning to the DSM-5
June 2013
1
PURPOSE OF THE DSM
 The purpose of a diagnostic and statistical manual is to provide
clear descriptions of diagnostic categories in order to enable
clinicians to diagnose, communicate about, study and treat
people with various disorders.
 DSM is used by health care professionals of all disciplines and it
is cited for insurance reimbursement, disability deliberations and
forensic matters
 DSM attempts to describe what the manifestations of mental
disorders are and provides a description of the clinical features
June 2013
2
MULTIAXIAL SYSTEM
 The DSM-IV (1994) adopted the multiaxial system
in its assessment and had influence in
recognizing environmental problems
 Axis I
 Axis II
 Axis III
 Axis IV
 Axis V
June 2013
3
MULTIAXIAL SYSTEM
 DSM 5 is doing away with the multiaxial system
 Axis III has been combined with Axis I and II and will
be included in a problem list
 Axis IV and Axis V have been dropped
June 2013
4
ORDER OF THE DSM-5
 The DSM-5 is arranged by category of mental
disorders (depressive disorders, anxiety
disorders, bipolar and related disorders,
neurodevelopmental disorders, etc.)
 The DSM-5 deleted the chapter that includes "all
diagnoses usually first made in infancy,
childhood, or adolescence", opting to list them in
other chapters
June 2013
5
ANXIETY DISORDERS
June 2013
6
 Panic disorder and agoraphobia become two
separate disorders in the DSM-5
 The generalized specifier for social anxiety
disorder(formerly, social phobia) changed in favor of a
performance only (i.e., public speaking or
performance) specifier
 Separation anxiety disorder and selective mutism are
now classified as anxiety disorders (rather than
disorders of early onset)
ATTENTION-
DEFICIT/HYPERACTIVITY
DISORDER
 The same 18 symptoms are used as in the DSM-IV,
and continue to be divided into two symptom
domains.
 Several changes have been made in the DSM-5:
 The cross-situational requirement has been
strengthened to “several” symptoms in each setting
 The onset criterion has been changed from “symptoms
that caused impairment were present before age 7
years” to “several inattentive or hyperactive-impulsive
symptoms were present prior to age 12”
 A comorbid diagnosis with autism spectrum disorder is
now allowed
 A symptom threshold change has been made for adults,
with the cutoff for ADHD of five symptoms, instead of six
required for younger persons.
June 2013
7
AUTISM SPECTRUM
DISORDER
 New DSM-5 name that reflects four previously
separate disorders combined into a single condition
with three levels of symptom severity in two core
domains
 Autistic Disorder
 Asperger’s disorder
 Childhood disintegrative disorder
 Pervasive Developmental Disorder NOS
 ASD is characterized by 1) deficits in social
communication and social interaction and 2) restricted
repetitive behaviors, interests, and activities.
June 2013
8
June 2013
9
SPECIFIC LEARNING
DISORDER
 Specific learning disorder combines the DSM-IV
diagnoses of reading disorder, mathematics
disorder, disorder of written expression, and
learning disorder NOS.
June 2013
10
OPPOSITIONAL DEFIANT
DISORDER
 Four refinements have been made to the criteria for
oppositional defiant disorder.
 Symptoms are now grouped into three types: angry/irritable
mood, argumentative/defiant behavior, and vindictiveness.
 The exclusion criterion for conduct disorder has been
removed.
 Given that many behaviors associated with symptoms of
oppositional defiant disorder occur commonly in normally
developing children and adolescents, a note has been added
to the criteria to provide guidance on the frequency typically
needed for a behavior to be considered symptomatic of the
disorder.
 A severity rating has been added to the criteria to reflect
research showing that the degree of pervasiveness of
symptoms across settings is an important indicator of severity
(mild, moderate and severe).
June 2013
11
June 2013
12
SCHIZOPHRENIA
 Two changes were made to DSM-IV Criterion A
for schizophrenia.
 Elimination of the special attribution of bizarre
delusions and first-rank auditory hallucinations (e.g.,
two or more voices conversing).
 The second change is the addition of a requirement
in Criterion A that the individual must have at least
one of these three symptoms: delusions,
hallucinations, and disorganized speech.
June 2013
13
June 2013
14
SCHIZOPHRENIA SUBTYPES
 The DSM-IV subtypes of schizophrenia (i.e.,
paranoid, disorganized, catatonic,
undifferentiated, and residual types) are
eliminated due to their limited diagnostic stability,
low reliability, and poor validity.
June 2013
15
SCHIZOAFFECTIVE DISORDER
 The primary change to schizoaffective disorder is
the requirement that a major mood episode be
present for a majority of the disorder’s total
duration after Criterion A (of schizophrenia) has
been met.
June 2013
16
BIPOLAR DISORDER
 To enhance the accuracy of diagnosis and
facilitate earlier detection in clinical settings,
Criterion A for manic and hypomanic episodes
now includes an emphasis on changes in activity
and energy as well as mood.
 The DSM-IV diagnosis of bipolar I disorder, mixed
episode, requiring that the individual
simultaneously meet full criteria for both mania
and major depressive episode, has been
removed. Instead, a new specifier, “with mixed
features,” has been added.
June 2013
17
June 2013
18
DEPRESSIVE DISORDERS
 DSM-5 contains several new depressive disorders
including:
 Dysthymia now falls under the category of persistent
depressive disorder, which includes both chronic major
depressive disorder and the previous dysthymic
disorder.
 Disruptive Mood Dysregulation Disorder
 PMDD
June 2013
19
June 2013
20
June 2013
21
BEREAVEMENT EXCLUSION
 In DSM-IV, there was an exclusion criterion for a
major depressive episode that was applied to
depressive symptoms lasting less than 2 months
following the death of a loved one. This exclusion is
omitted in DSM-5 for several reasons.
 To remove the implication that bereavement
typically lasts only 2 months when the duration is
more commonly 1–2 years.
 The depressive symptoms associated with
bereavement-related depression respond to the
same psychosocial and medication treatments as
non–bereavement-related depression.
June 2013
22
OBSESSIVE COMPULSIVE AND
RELATED DISORDERS
 The chapter on obsessive-compulsive and
related disorders, which is new in DSM-5,
reflects the increasing evidence that these
disorders are related to one another. New
disorders include:
 Substance-/medication-induced obsessive-
compulsive and related disorder, and
obsessive-compulsive and related disorder
due to another medical condition.
 Hoarding disorder
 Excoriation (skin-picking) disorder
June 2013
23
June 2013
24
June 2013
25
DISSOCIATIVE DISORDERS
 Major changes in dissociative disorders in DSM-5
include the following:
June 2013
26
June 2013
27
June 2013
28
June 2013
29
SOMATIC SYMPTOM AND
RELATED DISORDERS
 In DSM-IV, there was significant overlap across the somatoform
disorders and a lack of clarity about their boundaries. These
disorders are primarily seen in medical settings, and
nonpsychiatric physicians found the DSM-IV somatoform
diagnoses problematic to use.
 Diagnoses of somatization disorder, hypochondriasis, pain
disorder, and undifferentiated somatoform disorder have been
removed.
June 2013
30
June 2013
31
HYPOCHONDRIASIS
 Hypochondriasis has been eliminated as a
disorder, in part because the name was perceived
as derogatory and not conducive to an effective
therapeutic relationship.
 Most individuals who would previously have been
diagnosed with hypochondriasis have significant
somatic symptoms in addition to their high health
anxiety, and would now receive a DSM-5
diagnosis of somatic symptom disorder.
June 2013
32
June 2013
33
ANOREXIA NERVOSA
 The core diagnostic criteria for anorexia nervosa
are conceptually unchanged from DSM-IV with
one exception: the requirement for amenorrhea
has been eliminated.
 In DSM-IV, this requirement was waived in a
number of situations (e.g., for males, for females
taking contraceptives).
June 2013
34
June 2013
35
BINGE-EATING DISORDER
 The only significant difference from the
preliminary DSM-IV criteria is that the minimum
average frequency of binge eating required for
diagnosis has been changed from at least twice
weekly for 6 months to at least once weekly over
the last 3 months, which is identical to the DSM-5
frequency criterion for bulimia nervosa.
June 2013
36
SUBSTANCE-RELATED AND
ADDICTIVE DISORDERS
 The diagnosis of dependence caused much confusion in
the past
 Most people link dependence with “addiction” when in
fact dependence can be a normal body response to a
substance
 Substance use disorder in the DSM-5 combines the DSM-
IV categories of substance abuse and substance
dependence into a single disorder measured on a
continuum from mild to severe
 Each specific substance (other than caffeine, which
cannot be diagnosed as a substance use disorder) is
addressed as a separate use disorder (e.g., alcohol use
disorder, stimulant use disorder, etc.), but nearly all
substances are diagnosed based on the same overarching
criteria.
 Criteria for cannabis and caffeine withdrawal were added
June 2013
37
SUBSTANCE-RELATED AND
ADDICTIVE DISORDERS
June 2013
38
 Criteria for cannabis and caffeine withdrawal were
added
 Whereas a diagnosis of substance abuse
previously required only one symptom, mild
substance use disorder in DSM-5 requires two to
three symptoms from a list of 11
 Drug craving was added to the list
 Problems with law enforcement will be eliminated
because of cultural considerations that make the
criteria difficult to apply internationally
 Severity from mild to severe is based on the
number of criteria endorsed
June 2013
39
June 2013
40
GAMBLING DISORDER
 This change reflects the increasing and
consistent evidence that some behaviors, such as
gambling, activate the brain reward system with
effects similar to those of drugs of abuse and that
gambling disorder symptoms resemble substance
use disorders to a certain extent.
June 2013
41
June 2013
42
MAJOR AND MILD
NEUROCOGNITIVE DISORDER
 The DSM-IV diagnoses of dementia and amnesia are subsumed
under the newly named entity major neurocognitive disorder
(NCD).
 DSM-5 now recognizes a less severe level of cognitive
impairment, mild NCD, which is a new disorder that permits the
diagnosis of less disabling syndromes that may nonetheless be
the focus of concern and treatment.
 “The impact of the decline was noticeable, but clinicians
lacked a diagnosis to give patients,” noted Dr. Kupfer. There
were two reasons for this change: “(1) Opportunity for early
detection. The earlier the better for patients with these
symptoms. (2) It also encourages an early effective treatment
plan, ” before dementia sets in.
June 2013
43
June 2013
44
June 2013
45

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Rebecca Cowan Dsm 5 behavioral didactic

  • 1. Rebecca Cowan, PhD, LPC, NCC Eastern Virginia Medical School Department of Family & Community Medicine Transitioning to the DSM-5 June 2013 1
  • 2. PURPOSE OF THE DSM  The purpose of a diagnostic and statistical manual is to provide clear descriptions of diagnostic categories in order to enable clinicians to diagnose, communicate about, study and treat people with various disorders.  DSM is used by health care professionals of all disciplines and it is cited for insurance reimbursement, disability deliberations and forensic matters  DSM attempts to describe what the manifestations of mental disorders are and provides a description of the clinical features June 2013 2
  • 3. MULTIAXIAL SYSTEM  The DSM-IV (1994) adopted the multiaxial system in its assessment and had influence in recognizing environmental problems  Axis I  Axis II  Axis III  Axis IV  Axis V June 2013 3
  • 4. MULTIAXIAL SYSTEM  DSM 5 is doing away with the multiaxial system  Axis III has been combined with Axis I and II and will be included in a problem list  Axis IV and Axis V have been dropped June 2013 4
  • 5. ORDER OF THE DSM-5  The DSM-5 is arranged by category of mental disorders (depressive disorders, anxiety disorders, bipolar and related disorders, neurodevelopmental disorders, etc.)  The DSM-5 deleted the chapter that includes "all diagnoses usually first made in infancy, childhood, or adolescence", opting to list them in other chapters June 2013 5
  • 6. ANXIETY DISORDERS June 2013 6  Panic disorder and agoraphobia become two separate disorders in the DSM-5  The generalized specifier for social anxiety disorder(formerly, social phobia) changed in favor of a performance only (i.e., public speaking or performance) specifier  Separation anxiety disorder and selective mutism are now classified as anxiety disorders (rather than disorders of early onset)
  • 7. ATTENTION- DEFICIT/HYPERACTIVITY DISORDER  The same 18 symptoms are used as in the DSM-IV, and continue to be divided into two symptom domains.  Several changes have been made in the DSM-5:  The cross-situational requirement has been strengthened to “several” symptoms in each setting  The onset criterion has been changed from “symptoms that caused impairment were present before age 7 years” to “several inattentive or hyperactive-impulsive symptoms were present prior to age 12”  A comorbid diagnosis with autism spectrum disorder is now allowed  A symptom threshold change has been made for adults, with the cutoff for ADHD of five symptoms, instead of six required for younger persons. June 2013 7
  • 8. AUTISM SPECTRUM DISORDER  New DSM-5 name that reflects four previously separate disorders combined into a single condition with three levels of symptom severity in two core domains  Autistic Disorder  Asperger’s disorder  Childhood disintegrative disorder  Pervasive Developmental Disorder NOS  ASD is characterized by 1) deficits in social communication and social interaction and 2) restricted repetitive behaviors, interests, and activities. June 2013 8
  • 10. SPECIFIC LEARNING DISORDER  Specific learning disorder combines the DSM-IV diagnoses of reading disorder, mathematics disorder, disorder of written expression, and learning disorder NOS. June 2013 10
  • 11. OPPOSITIONAL DEFIANT DISORDER  Four refinements have been made to the criteria for oppositional defiant disorder.  Symptoms are now grouped into three types: angry/irritable mood, argumentative/defiant behavior, and vindictiveness.  The exclusion criterion for conduct disorder has been removed.  Given that many behaviors associated with symptoms of oppositional defiant disorder occur commonly in normally developing children and adolescents, a note has been added to the criteria to provide guidance on the frequency typically needed for a behavior to be considered symptomatic of the disorder.  A severity rating has been added to the criteria to reflect research showing that the degree of pervasiveness of symptoms across settings is an important indicator of severity (mild, moderate and severe). June 2013 11
  • 13. SCHIZOPHRENIA  Two changes were made to DSM-IV Criterion A for schizophrenia.  Elimination of the special attribution of bizarre delusions and first-rank auditory hallucinations (e.g., two or more voices conversing).  The second change is the addition of a requirement in Criterion A that the individual must have at least one of these three symptoms: delusions, hallucinations, and disorganized speech. June 2013 13
  • 15. SCHIZOPHRENIA SUBTYPES  The DSM-IV subtypes of schizophrenia (i.e., paranoid, disorganized, catatonic, undifferentiated, and residual types) are eliminated due to their limited diagnostic stability, low reliability, and poor validity. June 2013 15
  • 16. SCHIZOAFFECTIVE DISORDER  The primary change to schizoaffective disorder is the requirement that a major mood episode be present for a majority of the disorder’s total duration after Criterion A (of schizophrenia) has been met. June 2013 16
  • 17. BIPOLAR DISORDER  To enhance the accuracy of diagnosis and facilitate earlier detection in clinical settings, Criterion A for manic and hypomanic episodes now includes an emphasis on changes in activity and energy as well as mood.  The DSM-IV diagnosis of bipolar I disorder, mixed episode, requiring that the individual simultaneously meet full criteria for both mania and major depressive episode, has been removed. Instead, a new specifier, “with mixed features,” has been added. June 2013 17
  • 19. DEPRESSIVE DISORDERS  DSM-5 contains several new depressive disorders including:  Dysthymia now falls under the category of persistent depressive disorder, which includes both chronic major depressive disorder and the previous dysthymic disorder.  Disruptive Mood Dysregulation Disorder  PMDD June 2013 19
  • 22. BEREAVEMENT EXCLUSION  In DSM-IV, there was an exclusion criterion for a major depressive episode that was applied to depressive symptoms lasting less than 2 months following the death of a loved one. This exclusion is omitted in DSM-5 for several reasons.  To remove the implication that bereavement typically lasts only 2 months when the duration is more commonly 1–2 years.  The depressive symptoms associated with bereavement-related depression respond to the same psychosocial and medication treatments as non–bereavement-related depression. June 2013 22
  • 23. OBSESSIVE COMPULSIVE AND RELATED DISORDERS  The chapter on obsessive-compulsive and related disorders, which is new in DSM-5, reflects the increasing evidence that these disorders are related to one another. New disorders include:  Substance-/medication-induced obsessive- compulsive and related disorder, and obsessive-compulsive and related disorder due to another medical condition.  Hoarding disorder  Excoriation (skin-picking) disorder June 2013 23
  • 26. DISSOCIATIVE DISORDERS  Major changes in dissociative disorders in DSM-5 include the following: June 2013 26
  • 30. SOMATIC SYMPTOM AND RELATED DISORDERS  In DSM-IV, there was significant overlap across the somatoform disorders and a lack of clarity about their boundaries. These disorders are primarily seen in medical settings, and nonpsychiatric physicians found the DSM-IV somatoform diagnoses problematic to use.  Diagnoses of somatization disorder, hypochondriasis, pain disorder, and undifferentiated somatoform disorder have been removed. June 2013 30
  • 32. HYPOCHONDRIASIS  Hypochondriasis has been eliminated as a disorder, in part because the name was perceived as derogatory and not conducive to an effective therapeutic relationship.  Most individuals who would previously have been diagnosed with hypochondriasis have significant somatic symptoms in addition to their high health anxiety, and would now receive a DSM-5 diagnosis of somatic symptom disorder. June 2013 32
  • 34. ANOREXIA NERVOSA  The core diagnostic criteria for anorexia nervosa are conceptually unchanged from DSM-IV with one exception: the requirement for amenorrhea has been eliminated.  In DSM-IV, this requirement was waived in a number of situations (e.g., for males, for females taking contraceptives). June 2013 34
  • 36. BINGE-EATING DISORDER  The only significant difference from the preliminary DSM-IV criteria is that the minimum average frequency of binge eating required for diagnosis has been changed from at least twice weekly for 6 months to at least once weekly over the last 3 months, which is identical to the DSM-5 frequency criterion for bulimia nervosa. June 2013 36
  • 37. SUBSTANCE-RELATED AND ADDICTIVE DISORDERS  The diagnosis of dependence caused much confusion in the past  Most people link dependence with “addiction” when in fact dependence can be a normal body response to a substance  Substance use disorder in the DSM-5 combines the DSM- IV categories of substance abuse and substance dependence into a single disorder measured on a continuum from mild to severe  Each specific substance (other than caffeine, which cannot be diagnosed as a substance use disorder) is addressed as a separate use disorder (e.g., alcohol use disorder, stimulant use disorder, etc.), but nearly all substances are diagnosed based on the same overarching criteria.  Criteria for cannabis and caffeine withdrawal were added June 2013 37
  • 38. SUBSTANCE-RELATED AND ADDICTIVE DISORDERS June 2013 38  Criteria for cannabis and caffeine withdrawal were added  Whereas a diagnosis of substance abuse previously required only one symptom, mild substance use disorder in DSM-5 requires two to three symptoms from a list of 11  Drug craving was added to the list  Problems with law enforcement will be eliminated because of cultural considerations that make the criteria difficult to apply internationally  Severity from mild to severe is based on the number of criteria endorsed
  • 41. GAMBLING DISORDER  This change reflects the increasing and consistent evidence that some behaviors, such as gambling, activate the brain reward system with effects similar to those of drugs of abuse and that gambling disorder symptoms resemble substance use disorders to a certain extent. June 2013 41
  • 43. MAJOR AND MILD NEUROCOGNITIVE DISORDER  The DSM-IV diagnoses of dementia and amnesia are subsumed under the newly named entity major neurocognitive disorder (NCD).  DSM-5 now recognizes a less severe level of cognitive impairment, mild NCD, which is a new disorder that permits the diagnosis of less disabling syndromes that may nonetheless be the focus of concern and treatment.  “The impact of the decline was noticeable, but clinicians lacked a diagnosis to give patients,” noted Dr. Kupfer. There were two reasons for this change: “(1) Opportunity for early detection. The earlier the better for patients with these symptoms. (2) It also encourages an early effective treatment plan, ” before dementia sets in. June 2013 43

Editor's Notes

  1. The diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) in DSM-5 are similar to those in DSM-IV. The same 18 symptoms are used as in DSM-IV, and continue to be divided into two symptom domains (inattention and hyperactivity/impulsivity), of which at least six symptoms in one domain are required for diagnosis. However, several changes have been made in DSM-5: 1) examples have been added to the criterion items to facilitate application across the life span; 2) the cross-situational requirement has been strengthened to “several” symptoms in each setting; 3) the onset criterion has been changed from “symptoms that caused impairment were present before age 7 years” to “several inattentive or hyperactive-impulsive symptoms were present prior to age 12”; 4) subtypes have been replaced with presentation specifiers that map directly to the prior subtypes; 5) a comorbid diagnosis with autism spectrum disorder is now allowed; and 6) a symptom threshold change has been made for adults, to reflect their substantial evidence of clinically significant ADHD impairment, with the cutoff for ADHD of five symptoms, instead of six required for younger persons, both for inattention and for hyperactivity and impulsivity. Finally, ADHD was placed in the neurodevelopmental disorders chapter to reflect brain developmental correlates with ADHD and the DSM-5 decision to eliminate the DSM-IV chapter that includes all diagnoses usually first made in infancy, childhood, or adolescence. Attention deficit hyperactivity disorder (ADHD) has been modified somewhat, especially to emphasize that this disorder can continue into adulthood. The one “big” change (if you can call it that) is that you can be diagnosed with ADHD as an adult if you meet one less symptom than if you are a child. While that weakens the criteria marginally for adults, the criteria are also strengthened at the same time. For instance, the cross-situational requirement has been strengthened to “several” symptoms in each setting (you can’t be diagnosed with ADHD if it only happens in one setting, such as at work). The criteria were also relaxed a bit as the symptoms now have to had appeared before age 12, instead of before age 7.
  2. Autism spectrum disorder is a new DSM-5 name that reflects a scientific consensus that four previously separate disorders are actually a single condition with different levels of symptom severity in two core domains. ASD now encompasses the previous DSM-IV autistic disorder (autism), Asperger’s disorder, childhood disintegrative disorder, and pervasive developmental disorder not otherwise specified. ASD is characterized by 1) deficits in social communication and social interaction and 2) restricted repetitive behaviors, interests, and activities (RRBs). Because both components are required for diagnosis of ASD, social communication disorder is diagnosed if no RRBs are present.
  3. Two changes were made to DSM-IV Criterion A for schizophrenia. Elimination of the special attribution of bizarre delusions and first-rank auditory hallucinations (e.g., two or more voices conversing). In DSM-IV, only one such symptom was needed to meet the diagnostic requirement for Criterion A, instead of two of the other listed symptoms. This special attribution was removed due to the nonspecificity of Schneiderian symptoms and the poor reliability in distinguishing bizarre from nonbizarre delusions. Therefore, in DSM-5, two Criterion A symptoms are required for any diagnosis of schizophrenia. The second change is the addition of a requirement in Criterion A that the individual must have at least one of these three symptoms: delusions, hallucinations, and disorganized speech. At least one of these core “positive symptoms” is necessary for a reliable diagnosis of schizophrenia.
  4. The DSM-IV subtypes of schizophrenia (i.e., paranoid, disorganized, catatonic, undifferentiated, and residual types) are eliminated due to their limited diagnostic stability, low reliability, and poor validity. These subtypes also have not been shown to exhibit distinctive patterns of treatment response or longitudinal course. Instead, a dimensional approach to rating severity for the core symptoms of schizophrenia is included in Section III to capture the important heterogeneity in symptom type and severity expressed across individuals with psychotic disorders.
  5. The primary change to schizoaffective disorder is the requirement that a major mood episode be present for a majority of the disorder’s total duration after Criterion A (of schizophrenia) has been met. This change was made on both conceptual and psychometric grounds. It makes schizoaffective disorder a longitudinal instead of a cross-sectional diagnosis—more comparable to schizophrenia, bipolar disorder, and major depressive disorder, which are bridged by this condition. The change was also made to improve the reliability, diagnostic stability, and validity of this disorder, while recognizing that the characterization of patients with both psychotic and mood symptoms, either concurrently or at different points in their illness, has been a clinical challenge.
  6. To enhance the accuracy of diagnosis and facilitate earlier detection in clinical settings, Criterion A for manic and hypomanic episodes now includes an emphasis on changes in activity and energy as well as mood. The DSM-IV diagnosis of bipolar I disorder, mixed episode, requiring that the individual simultaneously meet full criteria for both mania and major depressive episode, has been removed. Instead, a new specifier, “with mixed features,” has been added that can be applied to episodes of mania or hypomania when depressive features are present, and to episodes of depression in the context of major depressive disorder or bipolar disorder when features of mania/hypomania are present.
  7. In DSM-IV, there was an exclusion criterion for a major depressive episode that was applied to depressive symptoms lasting less than 2 months following the death of a loved one (i.e., the bereavement exclusion). This exclusion is omitted in DSM-5 for several reasons. The first is to remove the implication that bereavement typically lasts only 2 months when both physicians and grief counselors recognize that the duration is more commonly 1–2 years. Second, bereavement is recognized as a severe psychosocial stressor that can precipitate a major depressive episode in a vulnerable individual, generally beginning soon after the loss. When major depressive disorder occurs in the context of bereavement, it adds an additional risk for suffering, feelings of worthlessness, suicidal ideation, poorer somatic health, worse interpersonal and work functioning, and an increased risk for persistent complex bereavement disorder, which is now described with explicit criteria in Conditions for Further Study in DSM-5 Section III. Third, bereavement-related major depression is most likely to occur in individuals with past personal and family histories of major depressive episodes. It is genetically influenced and is associated with similar personality characteristics, patterns of comorbidity, and risks of chronicity and/or recurrence as non–bereavement-related major depressive episodes. Finally, the depressive symptoms associated with bereavement-related depression respond to the same psychosocial and medication treatments as non–bereavement-related depression. In the criteria for major depressive disorder, a detailed footnote has replaced the more simplistic DSM-IV exclusion to aid clinicians in making the critical distinction between the symptoms characteristic of bereavement and those of a major depressive episode. Thus, although most people experiencing the loss of a loved one experience bereavement without developing a major depressive episode, evidence does not support the separation of loss of a loved one from other stressors in terms of its likelihood of precipitating a major depressive episode or the relative likelihood that the symptoms will remit spontaneously.