Immune Escape Mechanisms of Cancers and High Grade Glial Tumors

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Health & Medicine

IMMUNE ESCAPE MECHANISMS OF CANCERS AND HIGH
GRADE GLIAL TUMORS
1

19
Dendritic Cell
Treatment in GBM’s.
Both Glioblastoma
Associated Antigens
and Glioblastoma
Stem Cell Antigens
Can Be Used In
Addition To Tumor
Lysates, Tumor
RNA and Peptides
The Cell Dosage
Differs Between 1
Million to 10 Billion
of Dendritic Cells

24
Yin and Yang of Dendritic Cells in Cancer
Immunology

27
Expression of
Coinhibitory
Molecules
On Tumor Cell
Surface Limits
Antitumor
Responses And
Efficacy of
Dendritic Cell
Vaccination

28
Multiple Ways For
Cancer Immunotherapy
Cytokine secreting
tumor cells
Ex vivo Tumor Loaded
Dendritic Cells
Antibodies Agonistic
To Costimulatory
Lymphocyte Receptors
GITR and 4-1BB
Depletion of Treg’s
and MDSC’s

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