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1. Viagra is Good for the Heart
The blue pill (Sildenafilcitrate),whichcountlessmenrequire erectiondysfunction(Erectile dysfunction),
cuts downon the resultsof hormonal force onthe centerby half,basedonresearchprintedonline
withinthe journal Circulation.
The blue pill causesgenital bloodstreamvesselstogrow,whichwill helptomaintainahardererection.
Recentresearchalsoofferspointedtothe potentialeffectivenessforlunghypertension.Before the
latestfindingswithagroup of JohnsHopkinsresearchers,ithadbeenconsideredtohaven'tmuch
impacton the center.
The blue pill,orsildenafil,bluntsthe strengthenedheartbeatbroughtonbychemicallycausedstress,
basedon studyseniorauthorandcardiologistDavidKass,MD,a professorinthe JohnsHopkinsCollege
Med school andit isHeart Institute.Ittherefore lessensbothexcessquantityof bloodstreamandalso
the pressure accustomedtopumpit towardsthe body.
"Sildenafil effectivelyputsa'brake'on chemical stimulationfromthe heart,"statesKass.
PreventsandReversesResultsof HighBP
These bitsof informationare thoughttobe the veryfirstconfirmationinhumansthatThe blue pill has
an effectaroundthe heart.Inearlierresearch,Kassandthe team observedanidenticaleffectinrodents
Sildenafil blockedrapid-termresultsof hormonal stresswithinthe heart.
Relatedstudiesthroughthe groupreveal thatsildenafilalsopreventsandreversesthe lengthy-term
resultsof chronichighbloodstreampressure aroundthe heart.
Sildenafil reversedthe side effectsonheartmuscle weakenedoff byheartfailure andenlargement -- an
ailmentknownashypertrophy -- inmouse experimentsKassandthe teamtransportedoutcaptured.
Theyreportedtheirleadstothe journal Nature Medicine.

2. "But we'dno firmevidencewhetherorhow thistherapymightoperate ina personsheart,"statesKass.
"Our latestresearchprovidesfirmevidence thisdrugtrulydoescome withanimportanteffectonthe
center.Inch
ElevatedHeartbeatWasSlowed
Thirty-fivehealthywomenandmen,byhavinganaverage chronilogical age of 30 withnoprevious
indicationsof coronaryheart,tookpart inthe six-monthJohnsHopkinsstudy.Insideathree-hourtime-
frame,eachparticipantreceivedtwoseparate injectionsof dobutamine(5microgramsperkilogramfor
5 minutes),anartificial,adrenaline-like chemical thatincreasesheartbeatandpumpingstrength.
Betweeninjections,studyparticipantswere assignedatrandomto some groupwhichwas given
sildenafil (100milligramstakenorally) inordertoan organizationgivenasugar pill placebo.All
participantsthenreceivedthe 2nddobutamine injectiontodetermine whateffectssildenafil orplacebo
had aroundthe heart.
Measurementsof heartfunctionwere createdpre andposteachinjection.Theseincorporated
bloodstreampressurereadings,electrocardiogramsandechocardiograms.Bloodstreamsamples
confirmedrelativelyequalamountsof sildenafil alongwithotherenzymes.
Each dobutamine injectionstimulatedheartfunction,growingheartbeatandalsothe pressure of every
heartbeataccustomedtopumpbloodstreamthroughthe body,resultsdemonstrated.
"Thisstimulationiscomparable tohowacentral nervoussystemnormallyincreasesheartfunction
whentriggeredbyemotionalorexercise stress,orperhapsinillnessesforexample heartfailure,"notes
Kass.
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