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Hearing with two ears is
   better than with one


Dr. Dr. hc. Monika Lehnhardt


         May 2008
Glossary
Bilateral: Both sides
Bilateral cochlear implantation.(CI): CI placed
in the two cochleae of an individual patient.
Bimodal: Two different modes.
Bimodal Hearing: CI in one ear, Hearing Aid
(HA) on the non-implanted side.
Binaural Hearing: Integration of input along the
auditory pathway following sound/stimulation
from both ears.
A CI and an optimally fitted HA on the non-
implanted ear also provide binaural hearing
input to the auditory cortex.
How many bilateral Nucleus cochlear
              implant recipients are there
                 currently worldwide?

                       More than 5’500

                   of whom approximately 80%
                      are under the age of 18.



As of March 2008
Why is Binaural Hearing important?
The ability to localise sound as well the ability to
detect speech in complex acoustical environments
is achieved by the central auditory system’s ability
to calculate minute differences in the characteristics
of sound arriving at each ear.




 Sound arrives later and softer    Sound arrives earlier and
                                   louder
Improved sound localisation

         With a second CI,
         precision to localise sound
         more than doubles!


         Mean angular
                               67°
                          C I:
         error:
                      ral




                                                                                                          °
                 late




                                                                                                       24
             Uni



                                                                                               I:
                                                                                            lC
                                                                                          ra
                                                                                      at e
                                                                                  Bil
Verschuur, CA, Lutman, ME, Ramsden, R, Greehan, P, O’Driscoll, M., Auditory,
localization abilities in bilateral cochlear implant recipients. Otology and Neurology, 26:965-971. 2005
Improved speech
                                                         understanding in noise
                                                   With a second CI, speech understanding in
                                                   noise can increase by a factor of 9
            % correct scores for HSM at 10dB SNR




                                                   100
                                                    90
                                                    80                                            CI closest to noise
                                                    70
                                                    60




                                                                                    Factor of 9
                                                    50                                            CI closest to speech
                                                    40
                                                    30
                                                    20
                                                    10                                            Bilateral
                                                     0
                                                                                                  N=23
                                                         Speech +45 Noise -45
Laszig, R. et.al., Benefits of bilateral electrical stimulation with the nucleus cochlear implant in adults:
6-Month postoperative results, Otology and Neurotology, 25[6], 958-968. 2004.
What are the functional benefits of
 binaural hearing with CI?
• Feel safer
   – Better sound localisation
   – Being more aware of the sound environment

• Join in
   – Better speech understanding in noise
   – Socially more interactive in conversations

• Relax
  – Listening becomes easier
  – Enjoying more balanced sound
  – “Incidental learning”
  – Confidence that the better ear is implanted
What are the objective benefits of
                        binaural hearing with CI?
        a. Head shadow effect (a physical phenomenon):
           the benefit from adding the ear with the more
           favourable Signal-to-Noise Ratio when listening
           in spatially separated speech and noise.

                           Speech                                                           Noise

                                                                                               Mean improvement
                                                                                               of 10dB in Critical
                                                                                               SNR for 50%
                                                                                               speech recognition
                                                       *                                       for Oldenburger
                                                                                               sentences


Laszig, R. et.al., Benefits of bilateral electrical stimulation with the nucleus cochlear implant in adults: 6-
Month postoperative results, Otology and Neurotology, 25[6], 958-968. 2004.
What are the objective benefits of
                     binaural hearing with CI? (cont.)
          b. Binaural squelch – the benefit of adding the
            ear with the less favourable signal to noise ratio



                                                    Speech
                                                                                        Up to 3 dB
                                                                                        improvement in
                                                                                        SNR for speech
                                                                                        recognition
                                                         *
                                     Noise


Cochlear White paper B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in
Children and Adults. 2006
What are the objective benefits of
                     binaural hearing with CI? (cont.)
      c. Binaural Redundancy - two ears are better than
          one when listening to speech in quiet or in noise
                presented from the same location

                                              Speech
                                             and Noise
                                                                                     1 – 2 dB increase in
                                                                                     perceived loudness




                              Speec
                            and Noise
Cochlear White Paper. B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in
Children and Adults. 2006
Are two ears better than one?




  The Evidence Says, YES
• 37 of more than 300 studies selected
• Evidence indicates specially sound
  localisation and understanding in noise benefits
   – + 21% sentences score (in noise)
   – 24° instead of 67° localisation error
Bimodal Options: Candidacy
               Considerations
    Adults:
    Greatest binaural benefit (CI + contralateral
    HA) for improved speech understanding in
    quiet and in noise was observed for subjects
    who scored at least 20% correct on bisyllabic
    word lists pre-operatively with their
    contralateral HA.



Morera et al., Advantages of Binaural Hearing Provided through Bimodal
Stimulation via a Cochlear Implant and a Conventional Hearing Aid.: A 6 month
Comparative Study. Acta Otolaryngologica, 2005; 125: 596-606.
Bimodal Options: Candidacy
                              Considerations (cont.)
      Children:
      Degree of benefit from contralateral HA is related to:
      • Amount of residual hearing
      • Optimal HA fitting
      • Experience with bimodal hearing


      “Assuming consideration of the above, binaural gains
      are seen to be superior to the monaural condition
      and optimise academic and social functioning for the
      child”.
Cochlear White Paper . B. Robert Peters et al., Rationale for Bilateral Cochlear
Implantation in Children and Adults. 2006
When to progress from bimodal to
                  bilateral CI stimulation?
         Adults:
         Contralateral Aided Only condition:
         Two-thirds of polled clinical experts suggest
         further consideration of sequential CI if the
         subject scores 45% or less on open set word
         tests.
         Best Aided Bimodal listening condition:
         Experts suggest further consideration of
         sequential CI if the subject scores 55% or
         less on open set word tests.



Wyss, J (Ed.) Bilateral Expert Survey Consensus 2008 (in progress)
Bilateral CI candidacy considerations
          Children:
          An optimally fitted HA in the non-implanted ear
          will enable some maturation of the auditory
          pathways. This will occur, however, only to the
          degree related to the amount of residual hearing. 1
          The effectiveness of a hearing aid for this
          purpose can be monitored with CAEP.2
          In children whose CAEP (P1 latency) fails to show
          a time course of development, CI implantation is
          the only way to achieve central binaural
          development. 1
1. B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in Children and Adults. 2006
2. Sharma et al., P1 Latency as a Bio-Marker for Central Auditory Development in Children
with Hearing Impairment. J Am Acad Audiol 2005; 16: 568-577.
When to prefer simultaneous, when
     sequential bilateral cochlear
              implantation?
     Studies demonstrate a critical time period for
     binaural auditory development, more
     conducive to early simultaneous implantation.
  “Our data suggest a high degree of plasticity of the central auditory
  pathways seen only after early implantation (of bilateral implants)”.
       (Bauer PW, Sharma A et al. Central Auditory development in children with bilateral
            cochlear implants. Arch Otolaryngol Head Neck Surg. 2006 Oct;132(10)

   “Clear differences in auditory brainstem responses were seen in
 sequentially implanted children, even when the delay of the second
                     implant was under one year”.
(Gordon KA et al. Bilateral Best Practices Symposium, Charlotte, North Carolina, Apr 2007
re: Binaural processing in children using bilateral cochlear implants.Neuroreport. 2007 Apr
                                                 16)
Should the second ear be “saved” for
                  future CI technologies?
            “Given that binaural hearing depends on
            bilateral input during a critical development
            period, if the second ear does not receive
            auditory input during the critical period of
            cortical development, later technology, no
            matter how advanced, will only provide
            input to a cortex incapable of receiving it”



B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation
in Children and Adults. 2006
Is there an age effect for bilateral CI
                    implantation in children?
          Older children benefit,
          but less so compared
           to younger children

       In children under 8 yrs: the
       “gap” in speech perception
       for 1st vs. 2nd ears is closed
       within the first 6 -12
       months.
       This gap closure was generally not seen for
       children 8-13 yrs. Moreover, this gap persists
       even after 2 or 3 years, (except in isolated cases)

Peters BR, Litovsky R,Parkinson A, Lake J.Otol Neurotol.2007 May. Importance of Age and
Postimplantation Experience on Speech Perception Measures in Children with Sequential
Bilateral Cochlear Implants.
Age and Inter Implant Interval
                P1 Latency (ms)




Sharma et al., The Influence of a Sensitive Period on Central Auditory Development in Children
with Unilateral and Bilateral cochlear Implants. Hearing Research 2005; 203:134-143.
Age and Inter Implant Interval




Sharma et al., The Influence of a Sensitive Period on Central Auditory Development in Children
with Unilateral and Bilateral cochlear Implants. Hearing Research 2005; 203:134-143.
Is there Expert Consensus?
                   • Most would benefit from
                     binaural CI.
                    • There is a – not yet
                      fully understood-
                      ‘window of opportunity’
                      in children.
• Surgery is low risk, simultaneous
  procedure is to be considered from 6
  months of age.
• Insurance companies and governments
  should fund bilateral CI.
Hearing with two ears is better than with one-eng 2008-05

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Hearing with two ears is better than with one-eng 2008-05

  • 1. Hearing with two ears is better than with one Dr. Dr. hc. Monika Lehnhardt May 2008
  • 2. Glossary Bilateral: Both sides Bilateral cochlear implantation.(CI): CI placed in the two cochleae of an individual patient. Bimodal: Two different modes. Bimodal Hearing: CI in one ear, Hearing Aid (HA) on the non-implanted side. Binaural Hearing: Integration of input along the auditory pathway following sound/stimulation from both ears. A CI and an optimally fitted HA on the non- implanted ear also provide binaural hearing input to the auditory cortex.
  • 3. How many bilateral Nucleus cochlear implant recipients are there currently worldwide? More than 5’500 of whom approximately 80% are under the age of 18. As of March 2008
  • 4. Why is Binaural Hearing important? The ability to localise sound as well the ability to detect speech in complex acoustical environments is achieved by the central auditory system’s ability to calculate minute differences in the characteristics of sound arriving at each ear. Sound arrives later and softer Sound arrives earlier and louder
  • 5. Improved sound localisation With a second CI, precision to localise sound more than doubles! Mean angular 67° C I: error: ral ° late 24 Uni I: lC ra at e Bil Verschuur, CA, Lutman, ME, Ramsden, R, Greehan, P, O’Driscoll, M., Auditory, localization abilities in bilateral cochlear implant recipients. Otology and Neurology, 26:965-971. 2005
  • 6. Improved speech understanding in noise With a second CI, speech understanding in noise can increase by a factor of 9 % correct scores for HSM at 10dB SNR 100 90 80 CI closest to noise 70 60 Factor of 9 50 CI closest to speech 40 30 20 10 Bilateral 0 N=23 Speech +45 Noise -45 Laszig, R. et.al., Benefits of bilateral electrical stimulation with the nucleus cochlear implant in adults: 6-Month postoperative results, Otology and Neurotology, 25[6], 958-968. 2004.
  • 7. What are the functional benefits of binaural hearing with CI? • Feel safer – Better sound localisation – Being more aware of the sound environment • Join in – Better speech understanding in noise – Socially more interactive in conversations • Relax – Listening becomes easier – Enjoying more balanced sound – “Incidental learning” – Confidence that the better ear is implanted
  • 8. What are the objective benefits of binaural hearing with CI? a. Head shadow effect (a physical phenomenon): the benefit from adding the ear with the more favourable Signal-to-Noise Ratio when listening in spatially separated speech and noise. Speech Noise Mean improvement of 10dB in Critical SNR for 50% speech recognition * for Oldenburger sentences Laszig, R. et.al., Benefits of bilateral electrical stimulation with the nucleus cochlear implant in adults: 6- Month postoperative results, Otology and Neurotology, 25[6], 958-968. 2004.
  • 9. What are the objective benefits of binaural hearing with CI? (cont.) b. Binaural squelch – the benefit of adding the ear with the less favourable signal to noise ratio Speech Up to 3 dB improvement in SNR for speech recognition * Noise Cochlear White paper B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in Children and Adults. 2006
  • 10. What are the objective benefits of binaural hearing with CI? (cont.) c. Binaural Redundancy - two ears are better than one when listening to speech in quiet or in noise presented from the same location Speech and Noise 1 – 2 dB increase in perceived loudness Speec and Noise Cochlear White Paper. B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in Children and Adults. 2006
  • 11. Are two ears better than one? The Evidence Says, YES • 37 of more than 300 studies selected • Evidence indicates specially sound localisation and understanding in noise benefits – + 21% sentences score (in noise) – 24° instead of 67° localisation error
  • 12. Bimodal Options: Candidacy Considerations Adults: Greatest binaural benefit (CI + contralateral HA) for improved speech understanding in quiet and in noise was observed for subjects who scored at least 20% correct on bisyllabic word lists pre-operatively with their contralateral HA. Morera et al., Advantages of Binaural Hearing Provided through Bimodal Stimulation via a Cochlear Implant and a Conventional Hearing Aid.: A 6 month Comparative Study. Acta Otolaryngologica, 2005; 125: 596-606.
  • 13. Bimodal Options: Candidacy Considerations (cont.) Children: Degree of benefit from contralateral HA is related to: • Amount of residual hearing • Optimal HA fitting • Experience with bimodal hearing “Assuming consideration of the above, binaural gains are seen to be superior to the monaural condition and optimise academic and social functioning for the child”. Cochlear White Paper . B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in Children and Adults. 2006
  • 14. When to progress from bimodal to bilateral CI stimulation? Adults: Contralateral Aided Only condition: Two-thirds of polled clinical experts suggest further consideration of sequential CI if the subject scores 45% or less on open set word tests. Best Aided Bimodal listening condition: Experts suggest further consideration of sequential CI if the subject scores 55% or less on open set word tests. Wyss, J (Ed.) Bilateral Expert Survey Consensus 2008 (in progress)
  • 15. Bilateral CI candidacy considerations Children: An optimally fitted HA in the non-implanted ear will enable some maturation of the auditory pathways. This will occur, however, only to the degree related to the amount of residual hearing. 1 The effectiveness of a hearing aid for this purpose can be monitored with CAEP.2 In children whose CAEP (P1 latency) fails to show a time course of development, CI implantation is the only way to achieve central binaural development. 1 1. B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in Children and Adults. 2006 2. Sharma et al., P1 Latency as a Bio-Marker for Central Auditory Development in Children with Hearing Impairment. J Am Acad Audiol 2005; 16: 568-577.
  • 16. When to prefer simultaneous, when sequential bilateral cochlear implantation? Studies demonstrate a critical time period for binaural auditory development, more conducive to early simultaneous implantation. “Our data suggest a high degree of plasticity of the central auditory pathways seen only after early implantation (of bilateral implants)”. (Bauer PW, Sharma A et al. Central Auditory development in children with bilateral cochlear implants. Arch Otolaryngol Head Neck Surg. 2006 Oct;132(10) “Clear differences in auditory brainstem responses were seen in sequentially implanted children, even when the delay of the second implant was under one year”. (Gordon KA et al. Bilateral Best Practices Symposium, Charlotte, North Carolina, Apr 2007 re: Binaural processing in children using bilateral cochlear implants.Neuroreport. 2007 Apr 16)
  • 17. Should the second ear be “saved” for future CI technologies? “Given that binaural hearing depends on bilateral input during a critical development period, if the second ear does not receive auditory input during the critical period of cortical development, later technology, no matter how advanced, will only provide input to a cortex incapable of receiving it” B. Robert Peters et al., Rationale for Bilateral Cochlear Implantation in Children and Adults. 2006
  • 18. Is there an age effect for bilateral CI implantation in children? Older children benefit, but less so compared to younger children In children under 8 yrs: the “gap” in speech perception for 1st vs. 2nd ears is closed within the first 6 -12 months. This gap closure was generally not seen for children 8-13 yrs. Moreover, this gap persists even after 2 or 3 years, (except in isolated cases) Peters BR, Litovsky R,Parkinson A, Lake J.Otol Neurotol.2007 May. Importance of Age and Postimplantation Experience on Speech Perception Measures in Children with Sequential Bilateral Cochlear Implants.
  • 19. Age and Inter Implant Interval P1 Latency (ms) Sharma et al., The Influence of a Sensitive Period on Central Auditory Development in Children with Unilateral and Bilateral cochlear Implants. Hearing Research 2005; 203:134-143.
  • 20. Age and Inter Implant Interval Sharma et al., The Influence of a Sensitive Period on Central Auditory Development in Children with Unilateral and Bilateral cochlear Implants. Hearing Research 2005; 203:134-143.
  • 21. Is there Expert Consensus? • Most would benefit from binaural CI. • There is a – not yet fully understood- ‘window of opportunity’ in children. • Surgery is low risk, simultaneous procedure is to be considered from 6 months of age. • Insurance companies and governments should fund bilateral CI.