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Anti-cancer
Treatments
Dr. Mohammed Fathy, MD
Lecturer of Clinical Oncology
Zagazig University
Include
Surgery
Radiotherapy
TARGETED THERPY HORMONAL THERPY
Surgery
Lumpectomy
Quadrantectomy
Breast Conservative Surgery (BCS)
Mastectomy
Radical Surgery
Remove tumor + a rim of
normal tissue = margin
Remove entire organ + tumor
Lymphadenectomy
Spinal cord decompression Bypass gastric-bowel obstruction
Palliative Surgery
Axillary Lymph
Node Dissection
(ALND)
Radiotherapy
Ionizing Radiation
DNA damage
Direct,
Indirect
External Beam
RadioTherapy (EBRT) Brachytherapy
Fractionated Radiotherapy
Free radicals
Normal tissue
recovery
Chemotherapy
Interfere with cell division
Kill cancer cells
Combination ToxicityRegimen
Hormonal Therapy
Hypothalamic-
Pituitary-
Gondal Axis
Interfere with
Hormone
production
Interfere with
Hormone action
Prostate Cancer
Breast Cancer
Hormone
Dependent
Hormone
Responsive
Hormone
Sensitive
Targeted Therapy
Target
Imatinib
Specific Tyrosine Kinase
Inhibitors (TKI)
B-RAF Inhibitors
MEK Inhibitors
Monoclonal
Antibodies (Mab)
Small molecule
Trastuzumab
ImmunoTherapy
Anti-Checkpoints
Cancer cell evade
immune system
Cancer vaccine
Angiogenesis Inhibitors
Cancer can establish
its blood supply
Bevacizumab
Angiogenesis
Inhibitors
Synthetic Lethality
Cells can withstand with
one hit but two hits
PARBi (BRACm)

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Anticancer Treatment