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THE NEW TREATMENT
BY
ISOTONIC PLASMA.
(MODIFIED SEA WATER.)
BY A PHYSICIAN.
LONDON
J. WHITAKER & SONS,
12, Warwick Lane, E.C.
Plate
I.
Plate
II.
CASE
OF
INFANT
WITH
G
ASTRO-ENTERITIS
AND
CONDITION
FIVE
MONTHS
AFTER
COMMENCEMENT
MARASMUS.
OF
TREATMENT.
THE NEW TREATMENT BY
ISOTONIC PLASMA.
i.
M. Quinton : The Man and His Work.
Early in the new century, it began to be noised abroad
that a new remedial measure existed in nature, rival-
ling Radium itself in its wonder-working powers. Not
from the earth, but from the sea, had this fresh thera-
peutic force been obtained ;
it was evolved from sea
water as a basis. The sea plays a great part in the
biology and chemistry of the globe ;
not only does the
sea contain more than thirty of the chemical elements
known to man ;
it constitutes also a nutritive milieu
for innumerable forms of animal life, which derive
from their surroundings vigour and vitality.
Problems of vital importance concerning the con-
ditions of early life on the globe have for years been
under the skilled investigation of M. Rene Ouinton,
Professor of Comparative Physiology in the College
de France. Ouinton, whose scientific work places him
in the front rank of modern savants, has calculated
the composition of the primordial oceans at the
earliest period of biological times.
The fact was established that the earliest simplest
organisms were those of the sea, and not of the land ;
and science now accepts this discovery. What then
2
were the marine conditions favouring the life and the
well-being of these simple protoplasmic units ?
After establishing the fact that the first occurrence
of animal life was in the sea and not on land, Ouinton
next showed that the primordial oceans contained
.8 per cent, of dissolved inorganic matter. That is,
the fluid medium, in which the earliest organisms lived
and moved and had their being, which provided
nutriment and environment for them, was of this
degree of concentration. Now this, while of academic
interest, is further of very definite practical bearing
on life on the globe at the present day.
Elementary physiology teaches that the cells of
which all bodies are composed are bathed in a fluid
medium which is derived from the blood vessels. This
fluid medium, which nourishes all the cells of the
body, has also a saline concentration of .8 per cent.
That is, the concentration of the fluid in which
primordial organisms flourished, is identical with that
which bathes the cellular structures of nineteenth
century organisms.
So much for concentration ;
now for composition.
We investigate the other end of the chain of life —the
chemical composition of present-day living beings, and
of present day marine fluid as we find it in uncon-
taminated sea-water. The parallel continues to work
out : for the same chemical elements, in character and
number, which constitute the structure of animals,
are also those which, item for item, are found in sea-
water as we know it. The difference between old-time
and present-day sea-water is in its concentration ;
and
this will be referred to later.
Such generalisations as these could not fail to have
important therapeutic deductions. If the complex
solution of a certain saline concentration known as the
sea-water of primordial times, exercised a favourable
influence upon cell-life then, why not similar fluid of
Plate 111.
CASE OF GASTRO-ENTERITIS WITH MARASMUS.
Plate IV.
CONDITION THREE MONTHS AFTER COMMENCEMENT OF TREATMENT.
a similar saline concentration now ? The question was
put to the test ;
the results came out exactly as
expected. Uncontaminated sea- water, made “ iso-
tonic ” with the circulating fluid in man, has a potent,
far-reaching and highly beneficial influence on the
human body in many forms of disease.
For full thirteen years Quinton has given the deepest
study to the working out of these problems, and to their
culmination in a new curative method of great and
unexpected power. Every original investigation
requires an exponent to sum up in less technical
language the bearings of the scientific work on modern
life and thought. This function was undertaken for
Quinton by Dr. Bernard Arnulphy, physician
of Paris, who has laid the English reading public
under a great obligation by his lucid accounts,
during the last four years, of Quinton’s labour and
its results. Dr. Arnulpliy’s latest presentment of
this subject to lay readers is found in the quarterly
journal entitled The Quest /* and his article may
profitably be read by all interested in this subject.
Various French physicians of eminence associated
themselves with Quinton in determining the values of
“ isotonic plasma,” as Quinton styles his marine
product, in the treatment of disease. And as the investi-
gations proceeded, it became patent that there was
scarcely a form of chronic disease in which this plasma
might not profitably be used. In some dangerous,
and in some obstinate, maladies, the results of its use
were semi-miraculous. There is no investigation like
personal investigation ;
and at our recent visit to
M. Quinton’s clinic in the Rue d’Ouessant, in Paris,
we saw what was proof that a new era in medicine had
dawned.
Take the miserable plight of the countless infants
who die in large cities from malnutrition, sickness and
* Vide The Quest, pp. 489-504 for April, 1910.
6
diarrhoea. In our own East End they disappear like
chaff before the wind. In France, 70,000 of these
luckless bairns die annually. Quinton declares that
by his methods 60,000 of these sacrificed lives could
certainly be saved. That is less than the percentage
of such cases saved at his clinics. No spectacle is more
inspiring than one we witnessed in Paris. An emaciated
babe, looking like a little mummy, was brought into
the clinic. It was bluish in tint, its corneal reflex
had gone, its respirations were four to the minute,
its temperature was 40
0
C. The infant was dying—in
fact practically dead. An injection of Plasma was
immediately given. Within an hour a transformation
had been effected. There lay the babe alive and
active, with bright eyes, the appearance of death
vanished from its face, and with every mark of com-
mencing convalescence. It was a veritable resurrection.
And this is the type of case, and this the first step in
recovery, that one may see in a thousand instances at
Quinton’s clinic.
This case, and other cases, and photographs of
innumerable other derelict babes thus restored to life,
gave us material for reflection. The list of surprises
grows apace during the morning visit. Here is a case
of psoriasis —a peculiarly inveterate form—which has
afflicted the patient for a quarter of a century. With
Isotonic Plasma it has been very greatly benefited in six
weeks. Here is a case of varicose ulcer in the leg of an
old woman ;
she also had suffered from this painful
affliction for over twenty years ;
and in her case treat-
ment for six weeks had practically effected a cure.
An astonishing case of cure of tuberculous ulceration
presented itself in a girl. Here the ulcers were on the
neck and over the lower spine ;
and they were healed
over after the first injection. Truly the health still
remained to be restored ;
but the sores were no longer
sores after the first visit. Cases of eczema throng
Plate
V.
Plate
VI.
CASE
OF
ECZEMA
OF
THE
FACE,
OF
TWO
YEARS
DURATION.
CURE
BY
ISOTONIC
PLASMA
IN
SIXTEEN
DAYS,
9
the clinic, and it is here where the Isotonic Plasma
treatment is especially potent. So remarkable are
many of these cases that I reserve fuller details for
later in this article.
II.
The Method and Its Results.
The value of a new method of treatment is estimated
by just so much as it improves on procedures already
in use. It is most valuable when it effectively cures con-
ditions or cases hitherto considered as practically dere-
lict. It is further valuable when by it other diseased
states are cured more safely, quickly and pleasantly
than with other methods usually employed. M.
Quinton’s Isotonic Plasma, within its range of action,
does both. Certain acute affections hitherto exceed-
ingly dangerous, are restored to health in some ninety
per cent, of instances. Certain other affections of the
chronic type, often very resistant to therapeutic
measures, are swept into its curative net with a speed
and certainty which inspires the wish that all chronic
diseases could be as effectively dealt with.
The most illuminating example of the first category
—the cure of the practically derelict —is in that de-
vastating infantile disorder known as acute gastro-
enteritis. The wastage of infant life from this cause
is enormous. It is estimated that 70,000 children
die of this malady every year in France. Nor is the
mortality bill any less in populous centres nearer
home.
This type of case—that of an infant dying from
sickness, diarrhoea and wasting—swells the attendance
at M. Quinton’s clinics. At the Paris hospitals, after
a certain grade in gravity is reached—when the child
10
i .
,
in fact is almost moribund—the death rate expected
is about 90 per cent. These cases come in numbers
to Quinton’s clinics. I have seen such, with the glazed
eye, the occasional gasp for breath, the lividity of
collapse, the deathly sweat on the face—revived,
restored and ultimately made strong and well by the
bold use of Isotonic Plasma. M. Quinton states that
the cured cases under his methods have reached nearly
a hundred per cent, of those children where death is
usually considered almost inevitable.
Often the sickness- and diarrhoea are arrested after
the first injection. Sometimes so desperate is the
case that while the earlier injections stay the dangerous
symptoms, and bring the little sufferer back to assured
life, the complete restoration to health and vigour
requires weeks of constant treatment.
Picture in such cases a thin, miserable infant,
vomiting even each teaspoonful of water, and having
a dozen passages from the bowels in twenty-four
hours. When seen, the corneal reflex is lost, the face
and extremities chill, a cold sweat on the forehead,
the fontanelle depressed, the respirations sometimes
as low as half a dozen per minute. The child is dying
—as good as dead. Now mark the effect after the
injection of 100 c.c. of Plasma : the eyes brighten, the
face and extremities regain warmth, the respirations
increase, and often after the first dose the sickness
and diarrhoea disappear. Next day—'after further
injections in the interim—vigour and vitality show
themselves in the child as good as dead. It is a verit-
able resurrection.
Here is a typical history of cases such as these, which
swell mortality bills so frightfully : A child, six months
old, with white patches inside the mouth and about
the anus—and possibly through the digestive tract ;
the abdomen was sunken, the skin, wherever touched
by urinary moisture, eczematous. There was constant
Plate
V1L
Plate
VIIL
CASE
OF
ALOPECIA,
EXISTENT
FOR
SIX
YEARS.
RESULT
AT
THE
END
OF
TWO
YEARS’
PLASMA
TREATMENT.
SCROFULOUS
ULCERATED
GLANDS
IN
NECK.
THE
SAME,
AFTER
FOUR
MONTHS
TREATMENT.
15
vomiting, and at least a dozen passages daily from the
bowels. The extremities were shrunken, the face
icy cold, the corneal reflex almost gone, ioo c.c. of
Plasma were given twice during the first twenty-four
hours. Seen next day, the vomiting and diarrhoea
had stopped after the first injection ;
the abdominal
tone had returned, the face had a comparatively lively
appearance.
The accompanying illustrations— (Plates I. -IV.) —
depict two of these acute gastro-enteritic cases as they
were brought to the clinic, and also their progress
under treatment. The cases are typical, and need
no special description. In such instances, under
Isotonic Plasma treatment, the acute symptoms
subside, the shrunken extremities become plump, the
bones no longer protrude under the skin, and the full
well-being of the child is restored. The problem
of the wastage of infant life, so far as these cases
are concerned, seems solved by INI. Quinton’s treatment.
The little patients recover at home ;
they are not
taken into hospital ;
they are fed and nursed in
the surroundings under which they have fallen ill.
While the dramatic effects of Isotonic Plasma are
chiefly manifest in the acute gastro-enteritis of children,
its sway is scarcely less marvellous in various chronic
skin diseases. In numberless cases of eczema it has
won its spurs ;
intractable cases of psoriasis have
yielded to its use ;
and in tubercular and specific
ulceration it has produced healing in a few weeks in
cases that have continued for years.
Plate V. shows a patch of eczema on the face of a
girl. This eruption had been very resistant to treat-
ment, having proved recalcitrant to X Rays and to the
application of Radium. A series of injections of
Isotonic Plasma produced, within sixteen days, the
result seen in Plate VI. The eczema has vanished.
A very interesting case of alopecia is shown in
i6
Plate VII. The little patient had been in this unsightly
condition for six years. We saw her in the clinic in
October of last year, with the very presentable head of
hair shown in Plate VIII. It had required two years
treatment to bring this about ;
but the mass of hair
is probably as much as would have grown in two years
in a state of health. That is, the progress had probably
been continuous.
These examples, taken from some thousands of
carefully recorded cases in the records of M. Quinton’s
clinics, convey some idea of the wide range of Plasma
Therapeutics. In one type of case, the quantities of
Plasma necessary, and their prolonged repetition,
appear to indicate the method of cure as one of direct
supply of the normal saline constituents of the blood,
which the organism seems unable to derive continu-
ously from the usual sources. In yet another type
of case, the small doses requisite to cure, and the
immediate aggravation wrought by over-dose, warrant
the view that the curative process is due to active
selection, from the traces of metallic elements in the
Plasma, of the appropriate metal or salt in the infin-
itesimal quantity present. Let it be remembered that
the numerous elements, in bulk or in trace, present
in animal tissues, are exactly those existing, in bulk
or in trace, in Isotonic Plasma. A wider view is thus
opened out of the protective mechanism of the body
against disease—for what active part other than
protective can the infinitesimal fractions of the rarer
elements play in animal tissues ? —and the stimulation
of such protective mechanisms when the appropriate
elements, in natural infinitesimal quantity, are intro-
duced in a state of nature into the organism. But,
however we may speculate on methods, the facts are
there.
Plate XI
ECZEMA OF HANDS AND FOREARMS.
Plate XII.
THE SAME, AFTER TREATMENT DURING FIVE WEEKS.
//
i9
III.
Practical Utility.
There is practically no limit to the remedial range
of action of Isotonic Plasma, though hitherto it has
been chiefly utilised in diseases of the chronic type.
There is no reason for this restriction, as its specific
action in acute gastro-enteritic cases and in the
pyretic stages of tuberculosis indicates.
Naturally the curative powers of Plasma are not on
the same plane of directness for all maladies, or for all
patients.
Hypothesis apart, the actual remedial values of
Isotonic Plasma are so varied and so considerable as
to mark its introduction as a great advance in medi-
cine. In the accompanying Plates, Plate IX. is that
of a child with ulcerated tuberculous glands in the
neck. The treatment covered a period of four months,
from June 24th to October 20th ;
and the case may
be taken as one fairly resistant to treatment. Plate X.
shows the result.
Plate XI. shows eczema of the hands, and in Plate
XII. is depicted the cured condition. This required
five weeks to effect. In such cases the patients
continue their ordinary daily avocation while cure is
proceeding. It is unnecessary, as it is often impossible,
for work to be discontinued. The only external
application allowed is that of fomentations of cold
boiled water. Of a similar case, cured by seven
injections in twenty-two days. Quinton states :
Aucun traitcment adjuvant n’a ete employe. La
malade a continue a travailler.”
HEADLEY BROTHERS, PRINTERS, BISHOPSGATE, E.C. ; AND ASHFORI), KENT.
jSPi?-'.
spv
• •
B
it
|j|
“QUINTON POLYCLINIC
^ '
v‘
•*
r
f&L <
f
V
for the administration of
MODIFIED SEA WATER,
--
OPEN DAILY (Except Sundays),
at
57, POLAND STREET,
Oxford Street,
LONDON, W.

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Clinica quinton din londra

  • 1. u THE NEW TREATMENT BY ISOTONIC PLASMA. (MODIFIED SEA WATER.) BY A PHYSICIAN. LONDON J. WHITAKER & SONS, 12, Warwick Lane, E.C.
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  • 5. THE NEW TREATMENT BY ISOTONIC PLASMA. i. M. Quinton : The Man and His Work. Early in the new century, it began to be noised abroad that a new remedial measure existed in nature, rival- ling Radium itself in its wonder-working powers. Not from the earth, but from the sea, had this fresh thera- peutic force been obtained ; it was evolved from sea water as a basis. The sea plays a great part in the biology and chemistry of the globe ; not only does the sea contain more than thirty of the chemical elements known to man ; it constitutes also a nutritive milieu for innumerable forms of animal life, which derive from their surroundings vigour and vitality. Problems of vital importance concerning the con- ditions of early life on the globe have for years been under the skilled investigation of M. Rene Ouinton, Professor of Comparative Physiology in the College de France. Ouinton, whose scientific work places him in the front rank of modern savants, has calculated the composition of the primordial oceans at the earliest period of biological times. The fact was established that the earliest simplest organisms were those of the sea, and not of the land ; and science now accepts this discovery. What then
  • 6. 2 were the marine conditions favouring the life and the well-being of these simple protoplasmic units ? After establishing the fact that the first occurrence of animal life was in the sea and not on land, Ouinton next showed that the primordial oceans contained .8 per cent, of dissolved inorganic matter. That is, the fluid medium, in which the earliest organisms lived and moved and had their being, which provided nutriment and environment for them, was of this degree of concentration. Now this, while of academic interest, is further of very definite practical bearing on life on the globe at the present day. Elementary physiology teaches that the cells of which all bodies are composed are bathed in a fluid medium which is derived from the blood vessels. This fluid medium, which nourishes all the cells of the body, has also a saline concentration of .8 per cent. That is, the concentration of the fluid in which primordial organisms flourished, is identical with that which bathes the cellular structures of nineteenth century organisms. So much for concentration ; now for composition. We investigate the other end of the chain of life —the chemical composition of present-day living beings, and of present day marine fluid as we find it in uncon- taminated sea-water. The parallel continues to work out : for the same chemical elements, in character and number, which constitute the structure of animals, are also those which, item for item, are found in sea- water as we know it. The difference between old-time and present-day sea-water is in its concentration ; and this will be referred to later. Such generalisations as these could not fail to have important therapeutic deductions. If the complex solution of a certain saline concentration known as the sea-water of primordial times, exercised a favourable influence upon cell-life then, why not similar fluid of
  • 7. Plate 111. CASE OF GASTRO-ENTERITIS WITH MARASMUS. Plate IV. CONDITION THREE MONTHS AFTER COMMENCEMENT OF TREATMENT.
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  • 9. a similar saline concentration now ? The question was put to the test ; the results came out exactly as expected. Uncontaminated sea- water, made “ iso- tonic ” with the circulating fluid in man, has a potent, far-reaching and highly beneficial influence on the human body in many forms of disease. For full thirteen years Quinton has given the deepest study to the working out of these problems, and to their culmination in a new curative method of great and unexpected power. Every original investigation requires an exponent to sum up in less technical language the bearings of the scientific work on modern life and thought. This function was undertaken for Quinton by Dr. Bernard Arnulphy, physician of Paris, who has laid the English reading public under a great obligation by his lucid accounts, during the last four years, of Quinton’s labour and its results. Dr. Arnulpliy’s latest presentment of this subject to lay readers is found in the quarterly journal entitled The Quest /* and his article may profitably be read by all interested in this subject. Various French physicians of eminence associated themselves with Quinton in determining the values of “ isotonic plasma,” as Quinton styles his marine product, in the treatment of disease. And as the investi- gations proceeded, it became patent that there was scarcely a form of chronic disease in which this plasma might not profitably be used. In some dangerous, and in some obstinate, maladies, the results of its use were semi-miraculous. There is no investigation like personal investigation ; and at our recent visit to M. Quinton’s clinic in the Rue d’Ouessant, in Paris, we saw what was proof that a new era in medicine had dawned. Take the miserable plight of the countless infants who die in large cities from malnutrition, sickness and * Vide The Quest, pp. 489-504 for April, 1910.
  • 10. 6 diarrhoea. In our own East End they disappear like chaff before the wind. In France, 70,000 of these luckless bairns die annually. Quinton declares that by his methods 60,000 of these sacrificed lives could certainly be saved. That is less than the percentage of such cases saved at his clinics. No spectacle is more inspiring than one we witnessed in Paris. An emaciated babe, looking like a little mummy, was brought into the clinic. It was bluish in tint, its corneal reflex had gone, its respirations were four to the minute, its temperature was 40 0 C. The infant was dying—in fact practically dead. An injection of Plasma was immediately given. Within an hour a transformation had been effected. There lay the babe alive and active, with bright eyes, the appearance of death vanished from its face, and with every mark of com- mencing convalescence. It was a veritable resurrection. And this is the type of case, and this the first step in recovery, that one may see in a thousand instances at Quinton’s clinic. This case, and other cases, and photographs of innumerable other derelict babes thus restored to life, gave us material for reflection. The list of surprises grows apace during the morning visit. Here is a case of psoriasis —a peculiarly inveterate form—which has afflicted the patient for a quarter of a century. With Isotonic Plasma it has been very greatly benefited in six weeks. Here is a case of varicose ulcer in the leg of an old woman ; she also had suffered from this painful affliction for over twenty years ; and in her case treat- ment for six weeks had practically effected a cure. An astonishing case of cure of tuberculous ulceration presented itself in a girl. Here the ulcers were on the neck and over the lower spine ; and they were healed over after the first injection. Truly the health still remained to be restored ; but the sores were no longer sores after the first visit. Cases of eczema throng
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  • 13. 9 the clinic, and it is here where the Isotonic Plasma treatment is especially potent. So remarkable are many of these cases that I reserve fuller details for later in this article. II. The Method and Its Results. The value of a new method of treatment is estimated by just so much as it improves on procedures already in use. It is most valuable when it effectively cures con- ditions or cases hitherto considered as practically dere- lict. It is further valuable when by it other diseased states are cured more safely, quickly and pleasantly than with other methods usually employed. M. Quinton’s Isotonic Plasma, within its range of action, does both. Certain acute affections hitherto exceed- ingly dangerous, are restored to health in some ninety per cent, of instances. Certain other affections of the chronic type, often very resistant to therapeutic measures, are swept into its curative net with a speed and certainty which inspires the wish that all chronic diseases could be as effectively dealt with. The most illuminating example of the first category —the cure of the practically derelict —is in that de- vastating infantile disorder known as acute gastro- enteritis. The wastage of infant life from this cause is enormous. It is estimated that 70,000 children die of this malady every year in France. Nor is the mortality bill any less in populous centres nearer home. This type of case—that of an infant dying from sickness, diarrhoea and wasting—swells the attendance at M. Quinton’s clinics. At the Paris hospitals, after a certain grade in gravity is reached—when the child
  • 14. 10 i . , in fact is almost moribund—the death rate expected is about 90 per cent. These cases come in numbers to Quinton’s clinics. I have seen such, with the glazed eye, the occasional gasp for breath, the lividity of collapse, the deathly sweat on the face—revived, restored and ultimately made strong and well by the bold use of Isotonic Plasma. M. Quinton states that the cured cases under his methods have reached nearly a hundred per cent, of those children where death is usually considered almost inevitable. Often the sickness- and diarrhoea are arrested after the first injection. Sometimes so desperate is the case that while the earlier injections stay the dangerous symptoms, and bring the little sufferer back to assured life, the complete restoration to health and vigour requires weeks of constant treatment. Picture in such cases a thin, miserable infant, vomiting even each teaspoonful of water, and having a dozen passages from the bowels in twenty-four hours. When seen, the corneal reflex is lost, the face and extremities chill, a cold sweat on the forehead, the fontanelle depressed, the respirations sometimes as low as half a dozen per minute. The child is dying —as good as dead. Now mark the effect after the injection of 100 c.c. of Plasma : the eyes brighten, the face and extremities regain warmth, the respirations increase, and often after the first dose the sickness and diarrhoea disappear. Next day—'after further injections in the interim—vigour and vitality show themselves in the child as good as dead. It is a verit- able resurrection. Here is a typical history of cases such as these, which swell mortality bills so frightfully : A child, six months old, with white patches inside the mouth and about the anus—and possibly through the digestive tract ; the abdomen was sunken, the skin, wherever touched by urinary moisture, eczematous. There was constant
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  • 19. 15 vomiting, and at least a dozen passages daily from the bowels. The extremities were shrunken, the face icy cold, the corneal reflex almost gone, ioo c.c. of Plasma were given twice during the first twenty-four hours. Seen next day, the vomiting and diarrhoea had stopped after the first injection ; the abdominal tone had returned, the face had a comparatively lively appearance. The accompanying illustrations— (Plates I. -IV.) — depict two of these acute gastro-enteritic cases as they were brought to the clinic, and also their progress under treatment. The cases are typical, and need no special description. In such instances, under Isotonic Plasma treatment, the acute symptoms subside, the shrunken extremities become plump, the bones no longer protrude under the skin, and the full well-being of the child is restored. The problem of the wastage of infant life, so far as these cases are concerned, seems solved by INI. Quinton’s treatment. The little patients recover at home ; they are not taken into hospital ; they are fed and nursed in the surroundings under which they have fallen ill. While the dramatic effects of Isotonic Plasma are chiefly manifest in the acute gastro-enteritis of children, its sway is scarcely less marvellous in various chronic skin diseases. In numberless cases of eczema it has won its spurs ; intractable cases of psoriasis have yielded to its use ; and in tubercular and specific ulceration it has produced healing in a few weeks in cases that have continued for years. Plate V. shows a patch of eczema on the face of a girl. This eruption had been very resistant to treat- ment, having proved recalcitrant to X Rays and to the application of Radium. A series of injections of Isotonic Plasma produced, within sixteen days, the result seen in Plate VI. The eczema has vanished. A very interesting case of alopecia is shown in
  • 20. i6 Plate VII. The little patient had been in this unsightly condition for six years. We saw her in the clinic in October of last year, with the very presentable head of hair shown in Plate VIII. It had required two years treatment to bring this about ; but the mass of hair is probably as much as would have grown in two years in a state of health. That is, the progress had probably been continuous. These examples, taken from some thousands of carefully recorded cases in the records of M. Quinton’s clinics, convey some idea of the wide range of Plasma Therapeutics. In one type of case, the quantities of Plasma necessary, and their prolonged repetition, appear to indicate the method of cure as one of direct supply of the normal saline constituents of the blood, which the organism seems unable to derive continu- ously from the usual sources. In yet another type of case, the small doses requisite to cure, and the immediate aggravation wrought by over-dose, warrant the view that the curative process is due to active selection, from the traces of metallic elements in the Plasma, of the appropriate metal or salt in the infin- itesimal quantity present. Let it be remembered that the numerous elements, in bulk or in trace, present in animal tissues, are exactly those existing, in bulk or in trace, in Isotonic Plasma. A wider view is thus opened out of the protective mechanism of the body against disease—for what active part other than protective can the infinitesimal fractions of the rarer elements play in animal tissues ? —and the stimulation of such protective mechanisms when the appropriate elements, in natural infinitesimal quantity, are intro- duced in a state of nature into the organism. But, however we may speculate on methods, the facts are there.
  • 21. Plate XI ECZEMA OF HANDS AND FOREARMS. Plate XII. THE SAME, AFTER TREATMENT DURING FIVE WEEKS.
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  • 23. i9 III. Practical Utility. There is practically no limit to the remedial range of action of Isotonic Plasma, though hitherto it has been chiefly utilised in diseases of the chronic type. There is no reason for this restriction, as its specific action in acute gastro-enteritic cases and in the pyretic stages of tuberculosis indicates. Naturally the curative powers of Plasma are not on the same plane of directness for all maladies, or for all patients. Hypothesis apart, the actual remedial values of Isotonic Plasma are so varied and so considerable as to mark its introduction as a great advance in medi- cine. In the accompanying Plates, Plate IX. is that of a child with ulcerated tuberculous glands in the neck. The treatment covered a period of four months, from June 24th to October 20th ; and the case may be taken as one fairly resistant to treatment. Plate X. shows the result. Plate XI. shows eczema of the hands, and in Plate XII. is depicted the cured condition. This required five weeks to effect. In such cases the patients continue their ordinary daily avocation while cure is proceeding. It is unnecessary, as it is often impossible, for work to be discontinued. The only external application allowed is that of fomentations of cold boiled water. Of a similar case, cured by seven injections in twenty-two days. Quinton states : Aucun traitcment adjuvant n’a ete employe. La malade a continue a travailler.” HEADLEY BROTHERS, PRINTERS, BISHOPSGATE, E.C. ; AND ASHFORI), KENT.
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  • 26. “QUINTON POLYCLINIC ^ ' v‘ •* r f&L < f V for the administration of MODIFIED SEA WATER, -- OPEN DAILY (Except Sundays), at 57, POLAND STREET, Oxford Street, LONDON, W.