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neuroleukemianeurosurgeryneurosurgery.pptx
1. NEUROLEU A
i‹ s« rxLL andio-iz%o£AMLcases, if neuro-
prophylaxis is not given along with initial therapy.
• Pathnlugical lesions include infilhation by leukemia cells,
hcmc›rrhage, and demye inati .
Symptoms:
• Irtracranial hemorrhage.
• Hyper viscosity syndrome
2.
3.
4. TREATMENT
g for 6 duct•G. Asingle loveshould
Neuroprophylaxis:
IT MT*:iO-T4mg/m•thick a
not exmd i mg
• ITcYt arakinosidc omg twicea week for 6 closos
CNS involvement should be diagnosed when the CsF count
• 5fcumm with or without the presence nf blast cells.
• Cran or craniespinal irzadtation combined with IT MTx/ cytosine