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A Medical
Cannabis
Clinical
Model
A Medical Cannabis
Clinical Model
PROJECT SUMMARY
State of Washington Conundrum: There has been a great deal of success throughout the Medical
Cannabis Programs. Many of the State’s medical patients have found relief, both medically and
had tremendous cost savings to the state’s medical budget expenditures.
The safety of Medical Cannabis: There are no recorded deaths to date due to Cannabis.
care that they will provide. The time has come for an open commercial marketplace beyond what
currently exists. We have the following proposal to the conundrum:
VFCC Offers the State of Washington a Working Solution: This is a FULL SERVICE clinical model
that is designed to provide full medical and behavioral health components, with an array of services
delivered with the highest standard of professional medical care. The program is built to meet the
unique health care needs of the chronically ill, psychologically impaired, debilitated, and terminally ill,
as well as the very unique needs of Veterans’ communities within the State of Washington.
1
Drug overdose death rates in the US have
more than tripled since 1990.*
12
10
8
6
4
2
Deathrateper100,000population
1990 1992 1994 1996 1998 2000 2002 2004 2006 2008
A Medical Cannabis Clinical Model 2
A prospective Washington State medical patient with pain, psychological, rehabilitative, or palliative
care needs who is interested will be given the option of participating in a trial of Cannabis Botanical
Therapies as a primary or complementary adjunct treatment modality.
Patients are assisted in various ways through VFCC. As an organization, VFCC members will do the
following for their patients:
patients, develop, and deliver a treatment plan integrating indicated therapies that are appropriate and
authorized under state law to receive treatment.
VFCC IS A UNIQUE PROTOTYPE FOR OUR PROGRAM OF PATIENT
ADVOCACY STATEWIDE.
Reduction in Medical Expenditure:
revenue, with real time controls and full auditing provisions for any local, state or federal regulatory agencies.
Direct Securitization of Delivery of Medicine: A Pilot Medical Cannabis Clinic program will place
Professionals with experience in the delivery of Medical Therapies are involved at every step.
Quality Assurance of Pharmaceutical Grade Cannabis:
beginning with seed cultivation, and ensures that the standards of traditional medical care for the most
vulnerable of Washington’s citizens are fully implemented. We will NOT utilize any chemicals, pesticides or
butane products that may adversely affect the health of our patients and their families now or in the future.
Poly-substance Abuse Treatment Programs Save Money: Our Drug Rehabilitation Program will
models. The current medical literature reports a reduction in opioid usage upward of 40% with adjunct
cannabis therapy.
Home Health Care Changes Outcomes: Our Home Health Care Nursing model gives patients an
coverage with additional billing options for VA payments.
Robust State Jobs Program: Our model offers Veterans and the Disabled Community unique
job opportunities borne out of their own patient status. This provides for the unique opportunity for
A Medical Cannabis Clinical Model 3
Veterans whose lives have been improved and enriched to work and share this process with others
similar to themselves. “Pay it forward”.
Educational Opportunities:
continuing education, data collection, and research on cannabis and cannabis medical applications as
an adjunct to the State of Washington’s new educational program for doctors and health care providers.
.Our goal is to provide clinical data in a transparent manner to the Educational Community as an
ongoing analytical and cumulative effort for clinicians and researchers.
Economic Drivers for the State Budget: We will provide the State of Washington with economic
drivers to stimulate local economies statewide. The majority of the money generated will stay within the
local economies that support the local infrastructure.
applications.
CLINICAL OPERATING PROTOCOLS
CARF Accredited Trial Opioid Reduction Model: Using dosed cannabis extracts instead of
methadone in a structured regimented program: this model provides the Veteran community with
hope to Veterans who have had TBI and PTSD. The neuroplasticity reports are hopeful towards future
advances.
Direct Medicaid Spend-Down Savings: Clients can be directed into a cost effective program that
provides the necessary levels of comfort, including whole plant botanical substance and CBD enriched
hospice care: cannabis provision.
Real-Time Controls:
VFCC Jobs Program: This multifaceted organization will be a Veteran Promulgated Enterprise from
top to bottom with a distinct focus on Veteran employment opportunities. The goal of revitalizing
their own local communities as well as healing and restorative health will be established. Inclusive in
membership is open access to all operational sectors including agricultural development opportunities
and its Medical Professionals working with Veterans is the object of our goals for completion of this
unique model.
A Medical Cannabis Clinical Model 4
THERE IS NOT ONE VETERAN CARE CENTER LIKE THIS CURRENTLY IN
OPERATION IN THE UNITED STATES.
A Pilot Program: Wellness Therapeutic Cannabis Care
We are presenting a completely closed loop medical cannabis program and are seeking a form of
“hybrid” partnership with the State of Washington.
We are proffering the State of Washington a controlled and tightly regulated medical program that
compassionate cannabis laws. We seek to provide the State of Washington with a workable solution
Program that we have outlined here.
Our “hybrid” model is designed to utilize the funding provisions. Our unique
programs. We will also position ourselves to have fees appropriate for a sliding scale. We will be able to
Using CARF standards for this “Harm Reduction Opiate Program” and following the outlines for
methadone programs, we provide a clear structure and dosing outline that mirrors existing programs in
place today.
The standards and practices proposed for our Veterans for Compassionate Care programs exceed
those that are already in place for fully operational state and federally compliant medical programs. Our
operating procedures take into account the special circumstances of the current status of Cannabis/
Marijuana in current state regulatory process.
VETERANS FOR COMPASSIONATE CARE:
An Outreach Medical Cannabis Program for the Valiant:
With the Washington State Veterans population in excess of 400,000+ members from the Vietnam era
cannabis patient population, we will have a client base that has diagnoses which qualify them for our
program. The patient base suffers from PTSD, TBI, S/P amputations, chronic pain, depression, severe
the goal of: opioid reduction and cessation, decreased usage and ultimate discontinuation of addicting
benzodiazepines, discontinuation of mood modulators that have harmful side effects, and many other
A Medical Cannabis Clinical Model 5
“cocktail regimens” that have been prescribed for these Veterans in the hopes of improving their lives.
To date, these pharmacological agents have been unsuccessful to this growing patient population. The
suicide rate that has been quoted: 22 suicides per day among our Veterans who are currently under the
care of the Department Of Veterans Affairs. It is our belief that this number is much greater as many
widows and children without the stigma of suicide.
The complexities of these multiple diagnoses for Veterans leave them feeling alone and unable to cope
as current treatment modalities have not alleviated their real and severe medical and psychological
problems. As a direct result of the current medical community’s lack of resources to treat and
successfully manage these maladies, high suicide rates and other forms of desperate behaviors pose
serious statewide and national public health concerns.
For disorders that do not qualify under current Washington State qualifying conditions for the medical
VFCC’s program driven health care model: Provides specialized behavioral and physical health
applications of whole plant botanical cannabis substance delivery modalities and the Veteran
Community’s unique requirements.
CONDITIONS THAT ARE APPROVED AND RESPOND TO CANNABIS THERAPY:
ALS
MULTIPLE SCLEROSIS
ALZHEIMERS’ DISEASE
PARKINSON’S DISEASE
INTRACTABLE PAIN SYNDROMES
CANCER
HIV
AIDS
EPILEPSY
CROHN’S DISEASE
HEPATITIS B
HEPATITIS C
OTHER CONDITIONS SUBJECT TO STATE
APPROVAL: TRAUMATIC BRAIN INJURY, STROKE,
PTSD
A Medical Cannabis Clinical Model 6
MEDICAL CANNABIS DOSING STANDARDS:
An existing drawback to medical cannabis that our model resolves is how to determine a proper “Dosing
Schedule” for these various strains of Cannabis use. Our proposal showcases forms of delivery that have
shown to reliably expand treatment options while allowing proper medical supervision of such patients.
There is a growing body of data being collected at prestigious universities related to developing sound
across distinct patient loads for implementing new methods of delivery.
team and the support of the medical professionals from the Veterans’ Community, we will build a
unique new health care delivery model for medical cannabis treatment in a clinical care center, hospice,
inpatient and outpatient setting.
We will provide the following ancillary, multidisciplinary services:
provide cannabis medicines to patients we treat. We intend to offer a program model with fees for the
program participants billed per month for cannabis extracts with appropriate quantities of whole plant
botanical substance as warranted under established therapeutic guidelines.. Any additional whole plant
cannabis substance required to meet therapeutic needs will be made available for an additional amount
accordingly.
A Medical Cannabis Clinical Model 7
DATA AS COST SAVINGS
As we begin to accumulate data on our clinical operations, we will be able to provide access to the State
while continuing to lower the annual state budget in regards to medical care.
A HYBRID RESEARCH GRADE LICENSING:
Production – Processing – Clinically Dosed Delivery
“Commercial” marketplace, inclusive of the newly formed “recreational model”, as well as attempting now
Citizen/Patients.
With the state’s input at this crucial time, setting a new set of operating protocols that enshrine these two
distinct aspects of the new “Commercial Cannabis” marketplace can now be established.
Beginning with a Pilot Program of the form we seek, we can successfully move the State into a closed
loop driven system, operated by state approved medical professionals and overseen by state
Our current plan is to seek state approval and partnership to deliver products that comply with the
recently released Cannabis Monograph from the American Herbal Pharmacopoeia.
substances enables us to assert that we adhere to clean product protocols. Further, our laboratory-
grade process requires a unique operating protocol for delivering the type of product we are seeking
special state approval for.
We are fully prepared to offer a plan that includes this type of command and control over these
operations via direct licenses from the state. We will be able to assure the State that all plant matter is
tested and free from all pesticides and herbicides. As we are not dealing with the traditional concept
of cannabis being purchased by the ounce, we are providing all plant matter needed for the enrolled
patients’ needs as directed by the overseeing Medical Director or primary referring physician.
We will provide and have available all test results from state of the art independent testing facilities.
Agriculture: Control of genetics to provide stable and consistent CBD/THC plant strains that have known
the agricultural component of our program will be based upon plant count and not by the pound, as
currently prescribed. Whole plant botanical is needed to provide the THC and CBD extracts that are used
in a dosed regiment.
community so that treatment results can be replicated and be transparent. Under a closed loop program
A Medical Cannabis Clinical Model 8
procedures program will provide a transparent business model and allow for real time data collection for
the DSHS regarding enrolled clients’ improvement.
Alternatively, if circumstances warrant it and as regulations evolve, we are also fully prepared to move
Many of today’s operators could legitimately make this move up and facilitate the state
with a secure method of meeting the interim needs of such a medical cannabis program.
We want to submit a plan whereby the cream of the crop of these operators are given an opportunity
consistency into the Medical/Pharmaceutical Grade Cannabis system we would like to spearhead.
A NEW DAY DAWNING
This is an opportunity to set national standards that work for all concerned, the government, local
communities, support services and the most important component, the patients who use cannabis as the
least toxic method of pain management and wellness.
The uniqueness of our project presents the State of Washington with an opportunity to provide solutions
cannabis program that currently exists within Washington State.
In addition the Pilot Program we are proposing can form a reliable medical model going forward that will
provide insight and structure for the primary attending physicians who are now being directly tasked with
taking command of patient care as it relates to Cannabis Medicine.
strains that have been shown to provide relief to the suffering of certain medical issues that are quite unique.
At this historic time for the state of Washington, when a federally compliant commercial marketplace for
both Recreational and Medical Cannabis is needed, we urge the State to take this opportunity to approve
Veterans for Compassionate Care the right to advance this process to the next stage of development by
creating a “Medical Cannabis Care Center Model” that meets both the state and federal mandates for
medical care.
The full development of a Commercial Cannabis marketplace is what is needed to proceed ahead.
Crafting regulations around this process that allows for these two distinct aspects to exist side by side
is the challenge and we propose that the state allow us to proceed with a Pilot Program that can
showcase how this can be done. There are many citizens within the state who support a robust Cannabis
Community and who want to develop workable regulations based upon solid foundations.
Our goal now is to build out the model for Veterans for Compassionate Care through the outreach
program. We will bring qualifying medical cannabis patients into this new “Hybrid” designed program
medical cannabis program.
A Medical Cannabis Clinical Model 9
CARE CENTERS
The State of Washington’s citizens will be able to avail themselves of an established medical regimen
under a tightly controlled clinical environment with accurate and appropriate dosing therapeutics.
At our Care Center sites, we will be offering a wide variety of therapies that meet full state and federal
protocols and are appropriately established under existing reimbursement guidelines.
therapy is most effective for overcoming these barriers that prevent effective healing. Our patients will
may offer Cannabis garden tours as a form of Horticultural Therapy.
We will deliver compassionate care with transparency in our business model as we aim to convey a
form of “social equity” that enriches the public commons while developing a program model that
facilitates the medical needs of the citizens of Washington State.
will work with Matt Layton M.D., Medical Director for the College of Nursing Program of Excellence in
the Addiction Clinical Associate Professor, WSU Medical Sciences to provide training to their students in
the importance of this new emerging medical treatment modality.
Our model will provide ongoing training to physicians and nursing staff through our continuing
education programs. The multiple opportunities that the Spokane region offers includes a 60 bed
hospital facility that can be brought online and used for data collection and inpatient care .
This physical facility is located within 15 minutes of the Washington State University Medical School
We will be able to bring those citizens whose medical situations are clinically improved with their
primary attending physicians with real time data concerning their patients’ cannabis use within a clinical
setting. Future methods of improvement would include cognitive studies and further imaging testing.
We have designed a model that brings the current “Washington Collective Providers” into a producer
relationship with Allan Schreiber, Ph.D. who is the Chief of Agricultural Development and Research for VFCC.
We have a system for managing quality control of the various genetics that will become more
important to all working partners as we collect data and provide insight for the upcoming entry into the
marketplace of the pharmaceutical industry.
A Medical Cannabis Clinical Model 10
The advantages of a closed looped system medical cannabis program:
that allows for real time data collection for the DSHS regarding enrolled clients’ improvement. We
provide assurance that all state and federal regulations are being strictly followed as daily compliance
data will be mandatory and available for inspection.
VETERANS FOR COMPASSIONATE CARE SEEKS STATE WAIVER FOR
“RESEARCH-BASED CANNABIS CLINIC MODEL”
A Medical Cannabis Clinical Model 11
VETERANS FOR COMPASSIONATE CARE IS MAKING A DISTINCT REQUEST
FOR SPECIAL RECOGNITION APPROVAL AND PARTNERSHIP PROVISION
FROM THE STATE OF WASHINGTON FOR OPERATING A MEDICAL CANNABIS
CARE PROGRAM
We will be pleased to answer any and all questions concerning this proposal.
Rick Rosio, Director of Communications
Al Byrne CEO
Mary Lynn Mathre, RN, MSN, CARN, Director of Nursing and Education
Anne Lynn Morgan, M.D., Director of Medicine
Allan Schreiber, PhD, Director of Agricultural Research
Brother Fred Murphy SJ, Tom Bailey, Directors
Veterans for Compassionate Care
info@veteransforcompassionatecare.org
www.veteransforcompassionatecare.org
A Medical Cannabis Clinical Model 12
THE FOUNDING VETERANS
LCdr Al Byrne, SC, USN (ret.) –
Al Byrne is a retired LCdr of the U.S. Navy Supply Corps who served in Vietnam
of Time http://www.medicalcannabis.com and a board member of Veterans
for Medical Cannabis Access. Mr. Byrne has served on the planning committee
and as the program moderator for Patients Out of Time’s biennial conference
PTSD. He has had numerous articles published on the use of medical cannabis,
two weekly radio shows on Time4Hemp network.
Mary Lynn Mathre, RN, MSN, CARN, (USN Lt. ret.) –
MN in 1975 and began her nursing career in the U.S. Navy Nurse Corps.
She earned her MS degree from Case Western Reserve University in 1985
and her thesis was on Marijuana Disclosure to Health Care Professionals.
Originally a medical –surgical nurse, Ms. Mathre changed specialties in 1987
She began as the charge nurse on the Addiction Treatment Unit at the
the Addictions Consult Nurse for UVA Health System until 2002. She later
was Exec. Dir. of an opioid dependence treatment center in Charlottesville.
She is the editor of
the planning committee for Patients Out of Time’s national clinical cannabis conference series that
began in 2000; has authored numerous papers and chapters on medical cannabis; authored several
of medical cannabis at numerous local, regional, national and international conferences.
A Medical Cannabis Clinical Model 13
SSgt Mark DiPasquale, USMC (ret.)
foot prints in Paris Island, SC on July 17, 1994. Mark served in the United
States Marine Corps for 15 years with thirteen years of active service.
SSgt Mark DiPasquale endured two combat tours during Operation
as far east as Okinawa, Japan as well as 8 other duty stations. He was
honorably discharged and medically retired. He suffers from severe
migraines,cluster headaches since a hard crash landing in 2005 while
serving in Iraq, as well as PTSD. Mark also
received his B.S. in Criminal Justice from Roberts Wesleyan College in Rochester NY May 2013. In
2012 Mark founded Veterans for Alternative Care and lobbied for medical cannabis bill in the state of
New York, and educating Veterans around the nation about the medical values of cannabis and the
effectiveness it has when treating PTSD, TBI, and other war and service related injuries. In 2013 Mark
Compassionate Care.
Zack Lockwood, US Army (ret.)
the 45th as an Intelligence Analyst. He developed plans and routes for
throughout the regions he served. He was deployed overseas in Iraq
and Afghanistan. Zack transitioned from the military to college where
scheduling needs for Veterans for Alternative Care in Rochester, New York.
Sgt Edmond Tucker, USMC (ret.)
Marines I did two tours to Al Asad and Al Taqaddum Iraq, both as a
I had been promoted to a Sergeant of Marines, obtained Quality
Assurance Represented mechanic designation on two helicopters,
and graduated as a Weapons and Tactics Instructor. After leaving the
military I took a job contracting in Afghanistan for one year under
similar occupational likeliness. While working in Afghanistan I began
A Medical Cannabis Clinical Model 14
OPERATIONS TEAM
Lori Martinek –
Lori Martinek brings extensive experience in government relations and public
affairs to her work for Veterans For Compassionate Care. Her expertise in
marketing, public relations and stakeholder outreach in the economic and
enterprise development arenas has produced a successful track record for
building visibility for emerging and evolving organizations and industries.
and public sector clients. She is inspired by the VFCC mission, the challenge
of reshaping public opinion regarding cannabis, and the opportunity to help
create global visibility for the VFCC brand in the evolving medicinal cannabis sector.
An ardent supporter of both legalization and productive economic development, Lori is working to
help clients achieve success in the new cannabis economy. She has worked with U.S. Small Business
served as an SBA/SBDC enterprise development specialist in Arizona and Illinois. She has a passion
entrepreneurs.
Lori holds a Master’s degree in Marketing from Northwestern University’s prestigious Medill School of
Journalism, and a B.A. in Journalism from the University of Wisconsin – Madison. She began her career
clients including Coors, S. C. Johnson Company and First National Bank of Chicago.
Lori’s publishing credits include articles on brand management and marketing for national publications
published in 2009 by Herlife Publishing, another entrepreneurial venture.
Lori speaks to audiences across the country on topics including branding and social media marketing,
economic development marketing and entrepreneurship.
As Director of Stakeholder Development and Outreach for VFCC, Lori oversees global outreach,
stakeholder communications, media relations, social media strategies, public affairs and brand
management for our organization.
A Medical Cannabis Clinical Model 15
MEDICAL TEAM
Anne Lynn Morgan, MD –
Dr. Morgan is a Diplomate of the American Academy of Family Medicine.
She is an applicant for the Society of Cannabis Clinicians and the American
Academy of Cannabinoid Medicine and is a member of the International
Cannabis Research Society. She received her medical degree from C.E.T.E.C.
University in Santo Domingo, Dominican Republic. She completed her
Center, Orlando, Florida. and her Residency in Family Practice at Conemaugh
Valley Medical Center in Johnstown, Pennsylvania . She holds licenses
in Florida and Pennsylvania. Dr. Morgan has a keen interest in diseases
common to the Veteran and elder population. She is a former Medical Director for United Health,
Humana, and Metropolitan Health. She feels that educating the public and her colleagues about the
Endocannabinoid System in the human body will enhance their personal and professional lives as to
the therapeutics, preventative and curative aspects of this amazing and previously unknown system for
Uma V.A. Dhanabalan, MD, MPH, FAAFP –
Dr. Dhanabalan is a highly respected physician trained in Family Medicine
Academy of Family Physicians. She received her medical degree from the
University of Medicine and Dentistry of Newark, New Jersey, and her Master’s
Degree in Public Health specializing in Occupational and Environmental
Medicine from the Harvard School of Public Health. She received the Resident
Research Award from the American College of Occupational & Environmental
Medicine for her research project: “Occupational and Environmental Exposure
to Lead in South India.”
She is a clinical instructor at Tufts University School of Medicine in the Department of Public Health
and Family Medicine in Boston, Massachusetts, and an adjunct assistant professor at Emory University,
Rollins School of Public Health in the Department of Environmental and Occupational Health Atlanta,
illness. The tools and lectures created are used in health screening and for education. Dr. Dhanabalan
has worked for the Hanford Project in Richland, Washington. The Hanford site, created in 1943 as part
bomb detonated over Nagasaki, Japan. The operation at Hanford created one of the largest and most
complex cleanup projects in the U.S.. Weapons production resulted in more than 43 million cubic yards
A Medical Cannabis Clinical Model 16
of radioactive waste and over 130 million cubic yards of contaminated soil and debris. Dr. Dhanabalan
is the Medical Director for System Health, a revolutionary educational program bridging eastern and
western systems of medicine. The program aims to educate medical doctors and healthcare/holistic
practitioners in the foundation of systems theory as a basis for all systems of medicine – east and west,
for Wellbeing Systems Health TM.
Dr. Denis Petro, MD - Medical Advisor
in pharmaceutical research and development and medical practice. He
of stroke and advised Congress in writing the Orphan Drug Act of 1983.
muscle spasms in spasticity. While working with the pharmaceutical
industry, he developed a number of drugs for treatment of Parkinson
disease, chronic
in preparation of the IOM report on medical marijuana in 1997. He is recognized as an expert in
neurology and pharmacology by both the state and federal court systems of the U.S., as well as in
Canada and the United Kingdom.
David G. Ostrow, MD, PhD - Medical Advisor
Dr. Ostrow has been an Epidemiological, Prevention and Public Health
authority since the beginning of the AIDS epidemic. During his training in
sexual behavior, drug use and the evolution of HIV transmission and prevention among drug using
than 60 times at International AIDS conferences. He is an investigator or consultant on most of the
NIDA funded studies of drugs, alcohol and HIV in the MACS, including his own study of the Social and
study of the dynamic roles of social and risk networks as drivers of the increasing epidemic of new HIV
(Uma V.A. Dhanabalan, MD, MPH, FAAFP – Medical Advisor , cont.)
A Medical Cannabis Clinical Model 17
infections among younger Black MSM in Chicago. As the senior behavioral investigator in the MACS, he
plans to use the upcoming open recruitment of men at highest risk of or recently infected with HIV to
Since the late 1990s, Dr. Ostrow has been active in the movement to change failed national drug
policies, such as cannabis prohibition, with more effective and compassionate policies, including
regulation and legalization of cannabis use, integration of Cannabinoid Medicine training into the
Suzanne Sisley, MD –
Dr. Sisley is an assistant or, Internal Medicine/Psychiatry, at the University
of Arizona College of Medicine. She is Associate Director, Interprofessional
Education, Arizona Telemedicine Program.
In 2009, Sisley started working with reviewers at the FDA on a proposal to study
medical marijuana for veterans with PTSD. Approval came in 2011. It took another
three years for a different federal health agency to approve the study. Sisley
still must work with the DEA to obtain a Schedule I registration. There’s now a
government’s marijuana farm.
“Why would any scientist do this?” asked Sisley, who also works in private practice and has research
Dr. Alan Schreiber –
Dr. Schreiber has a B.S. in Biology, M.S. in Entomology and Ph.D. in Entomology/
Pesticide Toxicology. He does private research and consulting and is President
research on agricultural and conventional and organic pest management issues.
He consults on environmental, pesticide, pest management and Food Quality
Protection Act issues for grower groups, governmental organizations and
agribusinesses, including the National Potato Council, Oregon Seed Council,
Washington Red Raspberry Commission, Washington State Potato Commission,
and PNW dill growers. He provides administrative services for the Washington
State Commission on Pesticide Registration, a state governmental entity
dedicated to support of activities related to pesticide registration and pest management. He manages a
$0.5 million budget and interacts with all commodity and pest management groups, pest management
researchers and extension specialists in Washington. He is the Executive Director of the Washington
Asparagus Commission. In addition, he is the director of the Washington Blueberry Commission. He
was an assistant professor at Washington State University’s Department of Entomology/Food and
Environmental Quality Laboratory.
(David G. Ostrow, MD, PhD - Medical Advisor, cont.)
A Medical Cannabis Clinical Model 18
BIBLIOGRAPHY
human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem
Collaborating Centre: summary of the WHO Collaborating Centre for Neurotrauma Task Force on mild traumatic
Therapeutic Use of Marijuana. McFarland & Company
A Medical Cannabis Clinical Model 19
PTSD
Hill, et al.
world trade center attacks. Psychoneuoroendocrinology 38:2952, 2013
Hill, et al.
CB1 receptor agonists reverse chronic stress on perseveration behaviors. Neuropsychopharmacology 30:508, 2005
Marsicano, et al.
Amygdala CB1 receptors are required for proper extinction of fear memories. Nature 418:530, 2002
Neumeister, et al.
CB1 Receptors are unoccupied in brains of PTSD sufferers. Molecular Psychiatry 18:1043, 2013
Trezzu, V., Camplongo, P.
disorder. Frontiers in Behavioral Neuroscience, 2013, 7:100
Schier, et al.
Cannabidiol, a Cannabis Sativa constituent, as an anxiolytic drug. RBP Psychiatry, Volune 34, Supplement 1, June 2012
Chhatwal, J., et al.
Enhancing Cannibinoid Neurotransmission Augments the Extinction of Conditioned Fear.
MS
567.
A Medical Cannabis Clinical Model 20
Cardio
Epilespy
Blood Pressure
Appel LJ, Champagne CM, Harsha DW, Cooper LS, Obarzanek E, Elmer PJ, Stevens VJ, Vollmer WM, Lin PH, Svetkey LP, et al.
Anxiety
Alcohol
Bi-Polar
Neuropathic Pain
Anxiety
Alzheimer’s
Neuropathic Pain
TBI
Parkinson’s
Chronic Pain

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A Medical Cannabis Clinical Model

  • 2. A Medical Cannabis Clinical Model PROJECT SUMMARY State of Washington Conundrum: There has been a great deal of success throughout the Medical Cannabis Programs. Many of the State’s medical patients have found relief, both medically and had tremendous cost savings to the state’s medical budget expenditures. The safety of Medical Cannabis: There are no recorded deaths to date due to Cannabis. care that they will provide. The time has come for an open commercial marketplace beyond what currently exists. We have the following proposal to the conundrum: VFCC Offers the State of Washington a Working Solution: This is a FULL SERVICE clinical model that is designed to provide full medical and behavioral health components, with an array of services delivered with the highest standard of professional medical care. The program is built to meet the unique health care needs of the chronically ill, psychologically impaired, debilitated, and terminally ill, as well as the very unique needs of Veterans’ communities within the State of Washington. 1 Drug overdose death rates in the US have more than tripled since 1990.* 12 10 8 6 4 2 Deathrateper100,000population 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008
  • 3. A Medical Cannabis Clinical Model 2 A prospective Washington State medical patient with pain, psychological, rehabilitative, or palliative care needs who is interested will be given the option of participating in a trial of Cannabis Botanical Therapies as a primary or complementary adjunct treatment modality. Patients are assisted in various ways through VFCC. As an organization, VFCC members will do the following for their patients: patients, develop, and deliver a treatment plan integrating indicated therapies that are appropriate and authorized under state law to receive treatment. VFCC IS A UNIQUE PROTOTYPE FOR OUR PROGRAM OF PATIENT ADVOCACY STATEWIDE. Reduction in Medical Expenditure: revenue, with real time controls and full auditing provisions for any local, state or federal regulatory agencies. Direct Securitization of Delivery of Medicine: A Pilot Medical Cannabis Clinic program will place Professionals with experience in the delivery of Medical Therapies are involved at every step. Quality Assurance of Pharmaceutical Grade Cannabis: beginning with seed cultivation, and ensures that the standards of traditional medical care for the most vulnerable of Washington’s citizens are fully implemented. We will NOT utilize any chemicals, pesticides or butane products that may adversely affect the health of our patients and their families now or in the future. Poly-substance Abuse Treatment Programs Save Money: Our Drug Rehabilitation Program will models. The current medical literature reports a reduction in opioid usage upward of 40% with adjunct cannabis therapy. Home Health Care Changes Outcomes: Our Home Health Care Nursing model gives patients an coverage with additional billing options for VA payments. Robust State Jobs Program: Our model offers Veterans and the Disabled Community unique job opportunities borne out of their own patient status. This provides for the unique opportunity for
  • 4. A Medical Cannabis Clinical Model 3 Veterans whose lives have been improved and enriched to work and share this process with others similar to themselves. “Pay it forward”. Educational Opportunities: continuing education, data collection, and research on cannabis and cannabis medical applications as an adjunct to the State of Washington’s new educational program for doctors and health care providers. .Our goal is to provide clinical data in a transparent manner to the Educational Community as an ongoing analytical and cumulative effort for clinicians and researchers. Economic Drivers for the State Budget: We will provide the State of Washington with economic drivers to stimulate local economies statewide. The majority of the money generated will stay within the local economies that support the local infrastructure. applications. CLINICAL OPERATING PROTOCOLS CARF Accredited Trial Opioid Reduction Model: Using dosed cannabis extracts instead of methadone in a structured regimented program: this model provides the Veteran community with hope to Veterans who have had TBI and PTSD. The neuroplasticity reports are hopeful towards future advances. Direct Medicaid Spend-Down Savings: Clients can be directed into a cost effective program that provides the necessary levels of comfort, including whole plant botanical substance and CBD enriched hospice care: cannabis provision. Real-Time Controls: VFCC Jobs Program: This multifaceted organization will be a Veteran Promulgated Enterprise from top to bottom with a distinct focus on Veteran employment opportunities. The goal of revitalizing their own local communities as well as healing and restorative health will be established. Inclusive in membership is open access to all operational sectors including agricultural development opportunities and its Medical Professionals working with Veterans is the object of our goals for completion of this unique model.
  • 5. A Medical Cannabis Clinical Model 4 THERE IS NOT ONE VETERAN CARE CENTER LIKE THIS CURRENTLY IN OPERATION IN THE UNITED STATES. A Pilot Program: Wellness Therapeutic Cannabis Care We are presenting a completely closed loop medical cannabis program and are seeking a form of “hybrid” partnership with the State of Washington. We are proffering the State of Washington a controlled and tightly regulated medical program that compassionate cannabis laws. We seek to provide the State of Washington with a workable solution Program that we have outlined here. Our “hybrid” model is designed to utilize the funding provisions. Our unique programs. We will also position ourselves to have fees appropriate for a sliding scale. We will be able to Using CARF standards for this “Harm Reduction Opiate Program” and following the outlines for methadone programs, we provide a clear structure and dosing outline that mirrors existing programs in place today. The standards and practices proposed for our Veterans for Compassionate Care programs exceed those that are already in place for fully operational state and federally compliant medical programs. Our operating procedures take into account the special circumstances of the current status of Cannabis/ Marijuana in current state regulatory process. VETERANS FOR COMPASSIONATE CARE: An Outreach Medical Cannabis Program for the Valiant: With the Washington State Veterans population in excess of 400,000+ members from the Vietnam era cannabis patient population, we will have a client base that has diagnoses which qualify them for our program. The patient base suffers from PTSD, TBI, S/P amputations, chronic pain, depression, severe the goal of: opioid reduction and cessation, decreased usage and ultimate discontinuation of addicting benzodiazepines, discontinuation of mood modulators that have harmful side effects, and many other
  • 6. A Medical Cannabis Clinical Model 5 “cocktail regimens” that have been prescribed for these Veterans in the hopes of improving their lives. To date, these pharmacological agents have been unsuccessful to this growing patient population. The suicide rate that has been quoted: 22 suicides per day among our Veterans who are currently under the care of the Department Of Veterans Affairs. It is our belief that this number is much greater as many widows and children without the stigma of suicide. The complexities of these multiple diagnoses for Veterans leave them feeling alone and unable to cope as current treatment modalities have not alleviated their real and severe medical and psychological problems. As a direct result of the current medical community’s lack of resources to treat and successfully manage these maladies, high suicide rates and other forms of desperate behaviors pose serious statewide and national public health concerns. For disorders that do not qualify under current Washington State qualifying conditions for the medical VFCC’s program driven health care model: Provides specialized behavioral and physical health applications of whole plant botanical cannabis substance delivery modalities and the Veteran Community’s unique requirements. CONDITIONS THAT ARE APPROVED AND RESPOND TO CANNABIS THERAPY: ALS MULTIPLE SCLEROSIS ALZHEIMERS’ DISEASE PARKINSON’S DISEASE INTRACTABLE PAIN SYNDROMES CANCER HIV AIDS EPILEPSY CROHN’S DISEASE HEPATITIS B HEPATITIS C OTHER CONDITIONS SUBJECT TO STATE APPROVAL: TRAUMATIC BRAIN INJURY, STROKE, PTSD
  • 7. A Medical Cannabis Clinical Model 6 MEDICAL CANNABIS DOSING STANDARDS: An existing drawback to medical cannabis that our model resolves is how to determine a proper “Dosing Schedule” for these various strains of Cannabis use. Our proposal showcases forms of delivery that have shown to reliably expand treatment options while allowing proper medical supervision of such patients. There is a growing body of data being collected at prestigious universities related to developing sound across distinct patient loads for implementing new methods of delivery. team and the support of the medical professionals from the Veterans’ Community, we will build a unique new health care delivery model for medical cannabis treatment in a clinical care center, hospice, inpatient and outpatient setting. We will provide the following ancillary, multidisciplinary services: provide cannabis medicines to patients we treat. We intend to offer a program model with fees for the program participants billed per month for cannabis extracts with appropriate quantities of whole plant botanical substance as warranted under established therapeutic guidelines.. Any additional whole plant cannabis substance required to meet therapeutic needs will be made available for an additional amount accordingly.
  • 8. A Medical Cannabis Clinical Model 7 DATA AS COST SAVINGS As we begin to accumulate data on our clinical operations, we will be able to provide access to the State while continuing to lower the annual state budget in regards to medical care. A HYBRID RESEARCH GRADE LICENSING: Production – Processing – Clinically Dosed Delivery “Commercial” marketplace, inclusive of the newly formed “recreational model”, as well as attempting now Citizen/Patients. With the state’s input at this crucial time, setting a new set of operating protocols that enshrine these two distinct aspects of the new “Commercial Cannabis” marketplace can now be established. Beginning with a Pilot Program of the form we seek, we can successfully move the State into a closed loop driven system, operated by state approved medical professionals and overseen by state Our current plan is to seek state approval and partnership to deliver products that comply with the recently released Cannabis Monograph from the American Herbal Pharmacopoeia. substances enables us to assert that we adhere to clean product protocols. Further, our laboratory- grade process requires a unique operating protocol for delivering the type of product we are seeking special state approval for. We are fully prepared to offer a plan that includes this type of command and control over these operations via direct licenses from the state. We will be able to assure the State that all plant matter is tested and free from all pesticides and herbicides. As we are not dealing with the traditional concept of cannabis being purchased by the ounce, we are providing all plant matter needed for the enrolled patients’ needs as directed by the overseeing Medical Director or primary referring physician. We will provide and have available all test results from state of the art independent testing facilities. Agriculture: Control of genetics to provide stable and consistent CBD/THC plant strains that have known the agricultural component of our program will be based upon plant count and not by the pound, as currently prescribed. Whole plant botanical is needed to provide the THC and CBD extracts that are used in a dosed regiment. community so that treatment results can be replicated and be transparent. Under a closed loop program
  • 9. A Medical Cannabis Clinical Model 8 procedures program will provide a transparent business model and allow for real time data collection for the DSHS regarding enrolled clients’ improvement. Alternatively, if circumstances warrant it and as regulations evolve, we are also fully prepared to move Many of today’s operators could legitimately make this move up and facilitate the state with a secure method of meeting the interim needs of such a medical cannabis program. We want to submit a plan whereby the cream of the crop of these operators are given an opportunity consistency into the Medical/Pharmaceutical Grade Cannabis system we would like to spearhead. A NEW DAY DAWNING This is an opportunity to set national standards that work for all concerned, the government, local communities, support services and the most important component, the patients who use cannabis as the least toxic method of pain management and wellness. The uniqueness of our project presents the State of Washington with an opportunity to provide solutions cannabis program that currently exists within Washington State. In addition the Pilot Program we are proposing can form a reliable medical model going forward that will provide insight and structure for the primary attending physicians who are now being directly tasked with taking command of patient care as it relates to Cannabis Medicine. strains that have been shown to provide relief to the suffering of certain medical issues that are quite unique. At this historic time for the state of Washington, when a federally compliant commercial marketplace for both Recreational and Medical Cannabis is needed, we urge the State to take this opportunity to approve Veterans for Compassionate Care the right to advance this process to the next stage of development by creating a “Medical Cannabis Care Center Model” that meets both the state and federal mandates for medical care. The full development of a Commercial Cannabis marketplace is what is needed to proceed ahead. Crafting regulations around this process that allows for these two distinct aspects to exist side by side is the challenge and we propose that the state allow us to proceed with a Pilot Program that can showcase how this can be done. There are many citizens within the state who support a robust Cannabis Community and who want to develop workable regulations based upon solid foundations. Our goal now is to build out the model for Veterans for Compassionate Care through the outreach program. We will bring qualifying medical cannabis patients into this new “Hybrid” designed program medical cannabis program.
  • 10. A Medical Cannabis Clinical Model 9 CARE CENTERS The State of Washington’s citizens will be able to avail themselves of an established medical regimen under a tightly controlled clinical environment with accurate and appropriate dosing therapeutics. At our Care Center sites, we will be offering a wide variety of therapies that meet full state and federal protocols and are appropriately established under existing reimbursement guidelines. therapy is most effective for overcoming these barriers that prevent effective healing. Our patients will may offer Cannabis garden tours as a form of Horticultural Therapy. We will deliver compassionate care with transparency in our business model as we aim to convey a form of “social equity” that enriches the public commons while developing a program model that facilitates the medical needs of the citizens of Washington State. will work with Matt Layton M.D., Medical Director for the College of Nursing Program of Excellence in the Addiction Clinical Associate Professor, WSU Medical Sciences to provide training to their students in the importance of this new emerging medical treatment modality. Our model will provide ongoing training to physicians and nursing staff through our continuing education programs. The multiple opportunities that the Spokane region offers includes a 60 bed hospital facility that can be brought online and used for data collection and inpatient care . This physical facility is located within 15 minutes of the Washington State University Medical School We will be able to bring those citizens whose medical situations are clinically improved with their primary attending physicians with real time data concerning their patients’ cannabis use within a clinical setting. Future methods of improvement would include cognitive studies and further imaging testing. We have designed a model that brings the current “Washington Collective Providers” into a producer relationship with Allan Schreiber, Ph.D. who is the Chief of Agricultural Development and Research for VFCC. We have a system for managing quality control of the various genetics that will become more important to all working partners as we collect data and provide insight for the upcoming entry into the marketplace of the pharmaceutical industry.
  • 11. A Medical Cannabis Clinical Model 10 The advantages of a closed looped system medical cannabis program: that allows for real time data collection for the DSHS regarding enrolled clients’ improvement. We provide assurance that all state and federal regulations are being strictly followed as daily compliance data will be mandatory and available for inspection. VETERANS FOR COMPASSIONATE CARE SEEKS STATE WAIVER FOR “RESEARCH-BASED CANNABIS CLINIC MODEL”
  • 12. A Medical Cannabis Clinical Model 11 VETERANS FOR COMPASSIONATE CARE IS MAKING A DISTINCT REQUEST FOR SPECIAL RECOGNITION APPROVAL AND PARTNERSHIP PROVISION FROM THE STATE OF WASHINGTON FOR OPERATING A MEDICAL CANNABIS CARE PROGRAM We will be pleased to answer any and all questions concerning this proposal. Rick Rosio, Director of Communications Al Byrne CEO Mary Lynn Mathre, RN, MSN, CARN, Director of Nursing and Education Anne Lynn Morgan, M.D., Director of Medicine Allan Schreiber, PhD, Director of Agricultural Research Brother Fred Murphy SJ, Tom Bailey, Directors Veterans for Compassionate Care info@veteransforcompassionatecare.org www.veteransforcompassionatecare.org
  • 13. A Medical Cannabis Clinical Model 12 THE FOUNDING VETERANS LCdr Al Byrne, SC, USN (ret.) – Al Byrne is a retired LCdr of the U.S. Navy Supply Corps who served in Vietnam of Time http://www.medicalcannabis.com and a board member of Veterans for Medical Cannabis Access. Mr. Byrne has served on the planning committee and as the program moderator for Patients Out of Time’s biennial conference PTSD. He has had numerous articles published on the use of medical cannabis, two weekly radio shows on Time4Hemp network. Mary Lynn Mathre, RN, MSN, CARN, (USN Lt. ret.) – MN in 1975 and began her nursing career in the U.S. Navy Nurse Corps. She earned her MS degree from Case Western Reserve University in 1985 and her thesis was on Marijuana Disclosure to Health Care Professionals. Originally a medical –surgical nurse, Ms. Mathre changed specialties in 1987 She began as the charge nurse on the Addiction Treatment Unit at the the Addictions Consult Nurse for UVA Health System until 2002. She later was Exec. Dir. of an opioid dependence treatment center in Charlottesville. She is the editor of the planning committee for Patients Out of Time’s national clinical cannabis conference series that began in 2000; has authored numerous papers and chapters on medical cannabis; authored several of medical cannabis at numerous local, regional, national and international conferences.
  • 14. A Medical Cannabis Clinical Model 13 SSgt Mark DiPasquale, USMC (ret.) foot prints in Paris Island, SC on July 17, 1994. Mark served in the United States Marine Corps for 15 years with thirteen years of active service. SSgt Mark DiPasquale endured two combat tours during Operation as far east as Okinawa, Japan as well as 8 other duty stations. He was honorably discharged and medically retired. He suffers from severe migraines,cluster headaches since a hard crash landing in 2005 while serving in Iraq, as well as PTSD. Mark also received his B.S. in Criminal Justice from Roberts Wesleyan College in Rochester NY May 2013. In 2012 Mark founded Veterans for Alternative Care and lobbied for medical cannabis bill in the state of New York, and educating Veterans around the nation about the medical values of cannabis and the effectiveness it has when treating PTSD, TBI, and other war and service related injuries. In 2013 Mark Compassionate Care. Zack Lockwood, US Army (ret.) the 45th as an Intelligence Analyst. He developed plans and routes for throughout the regions he served. He was deployed overseas in Iraq and Afghanistan. Zack transitioned from the military to college where scheduling needs for Veterans for Alternative Care in Rochester, New York. Sgt Edmond Tucker, USMC (ret.) Marines I did two tours to Al Asad and Al Taqaddum Iraq, both as a I had been promoted to a Sergeant of Marines, obtained Quality Assurance Represented mechanic designation on two helicopters, and graduated as a Weapons and Tactics Instructor. After leaving the military I took a job contracting in Afghanistan for one year under similar occupational likeliness. While working in Afghanistan I began
  • 15. A Medical Cannabis Clinical Model 14 OPERATIONS TEAM Lori Martinek – Lori Martinek brings extensive experience in government relations and public affairs to her work for Veterans For Compassionate Care. Her expertise in marketing, public relations and stakeholder outreach in the economic and enterprise development arenas has produced a successful track record for building visibility for emerging and evolving organizations and industries. and public sector clients. She is inspired by the VFCC mission, the challenge of reshaping public opinion regarding cannabis, and the opportunity to help create global visibility for the VFCC brand in the evolving medicinal cannabis sector. An ardent supporter of both legalization and productive economic development, Lori is working to help clients achieve success in the new cannabis economy. She has worked with U.S. Small Business served as an SBA/SBDC enterprise development specialist in Arizona and Illinois. She has a passion entrepreneurs. Lori holds a Master’s degree in Marketing from Northwestern University’s prestigious Medill School of Journalism, and a B.A. in Journalism from the University of Wisconsin – Madison. She began her career clients including Coors, S. C. Johnson Company and First National Bank of Chicago. Lori’s publishing credits include articles on brand management and marketing for national publications published in 2009 by Herlife Publishing, another entrepreneurial venture. Lori speaks to audiences across the country on topics including branding and social media marketing, economic development marketing and entrepreneurship. As Director of Stakeholder Development and Outreach for VFCC, Lori oversees global outreach, stakeholder communications, media relations, social media strategies, public affairs and brand management for our organization.
  • 16. A Medical Cannabis Clinical Model 15 MEDICAL TEAM Anne Lynn Morgan, MD – Dr. Morgan is a Diplomate of the American Academy of Family Medicine. She is an applicant for the Society of Cannabis Clinicians and the American Academy of Cannabinoid Medicine and is a member of the International Cannabis Research Society. She received her medical degree from C.E.T.E.C. University in Santo Domingo, Dominican Republic. She completed her Center, Orlando, Florida. and her Residency in Family Practice at Conemaugh Valley Medical Center in Johnstown, Pennsylvania . She holds licenses in Florida and Pennsylvania. Dr. Morgan has a keen interest in diseases common to the Veteran and elder population. She is a former Medical Director for United Health, Humana, and Metropolitan Health. She feels that educating the public and her colleagues about the Endocannabinoid System in the human body will enhance their personal and professional lives as to the therapeutics, preventative and curative aspects of this amazing and previously unknown system for Uma V.A. Dhanabalan, MD, MPH, FAAFP – Dr. Dhanabalan is a highly respected physician trained in Family Medicine Academy of Family Physicians. She received her medical degree from the University of Medicine and Dentistry of Newark, New Jersey, and her Master’s Degree in Public Health specializing in Occupational and Environmental Medicine from the Harvard School of Public Health. She received the Resident Research Award from the American College of Occupational & Environmental Medicine for her research project: “Occupational and Environmental Exposure to Lead in South India.” She is a clinical instructor at Tufts University School of Medicine in the Department of Public Health and Family Medicine in Boston, Massachusetts, and an adjunct assistant professor at Emory University, Rollins School of Public Health in the Department of Environmental and Occupational Health Atlanta, illness. The tools and lectures created are used in health screening and for education. Dr. Dhanabalan has worked for the Hanford Project in Richland, Washington. The Hanford site, created in 1943 as part bomb detonated over Nagasaki, Japan. The operation at Hanford created one of the largest and most complex cleanup projects in the U.S.. Weapons production resulted in more than 43 million cubic yards
  • 17. A Medical Cannabis Clinical Model 16 of radioactive waste and over 130 million cubic yards of contaminated soil and debris. Dr. Dhanabalan is the Medical Director for System Health, a revolutionary educational program bridging eastern and western systems of medicine. The program aims to educate medical doctors and healthcare/holistic practitioners in the foundation of systems theory as a basis for all systems of medicine – east and west, for Wellbeing Systems Health TM. Dr. Denis Petro, MD - Medical Advisor in pharmaceutical research and development and medical practice. He of stroke and advised Congress in writing the Orphan Drug Act of 1983. muscle spasms in spasticity. While working with the pharmaceutical industry, he developed a number of drugs for treatment of Parkinson disease, chronic in preparation of the IOM report on medical marijuana in 1997. He is recognized as an expert in neurology and pharmacology by both the state and federal court systems of the U.S., as well as in Canada and the United Kingdom. David G. Ostrow, MD, PhD - Medical Advisor Dr. Ostrow has been an Epidemiological, Prevention and Public Health authority since the beginning of the AIDS epidemic. During his training in sexual behavior, drug use and the evolution of HIV transmission and prevention among drug using than 60 times at International AIDS conferences. He is an investigator or consultant on most of the NIDA funded studies of drugs, alcohol and HIV in the MACS, including his own study of the Social and study of the dynamic roles of social and risk networks as drivers of the increasing epidemic of new HIV (Uma V.A. Dhanabalan, MD, MPH, FAAFP – Medical Advisor , cont.)
  • 18. A Medical Cannabis Clinical Model 17 infections among younger Black MSM in Chicago. As the senior behavioral investigator in the MACS, he plans to use the upcoming open recruitment of men at highest risk of or recently infected with HIV to Since the late 1990s, Dr. Ostrow has been active in the movement to change failed national drug policies, such as cannabis prohibition, with more effective and compassionate policies, including regulation and legalization of cannabis use, integration of Cannabinoid Medicine training into the Suzanne Sisley, MD – Dr. Sisley is an assistant or, Internal Medicine/Psychiatry, at the University of Arizona College of Medicine. She is Associate Director, Interprofessional Education, Arizona Telemedicine Program. In 2009, Sisley started working with reviewers at the FDA on a proposal to study medical marijuana for veterans with PTSD. Approval came in 2011. It took another three years for a different federal health agency to approve the study. Sisley still must work with the DEA to obtain a Schedule I registration. There’s now a government’s marijuana farm. “Why would any scientist do this?” asked Sisley, who also works in private practice and has research Dr. Alan Schreiber – Dr. Schreiber has a B.S. in Biology, M.S. in Entomology and Ph.D. in Entomology/ Pesticide Toxicology. He does private research and consulting and is President research on agricultural and conventional and organic pest management issues. He consults on environmental, pesticide, pest management and Food Quality Protection Act issues for grower groups, governmental organizations and agribusinesses, including the National Potato Council, Oregon Seed Council, Washington Red Raspberry Commission, Washington State Potato Commission, and PNW dill growers. He provides administrative services for the Washington State Commission on Pesticide Registration, a state governmental entity dedicated to support of activities related to pesticide registration and pest management. He manages a $0.5 million budget and interacts with all commodity and pest management groups, pest management researchers and extension specialists in Washington. He is the Executive Director of the Washington Asparagus Commission. In addition, he is the director of the Washington Blueberry Commission. He was an assistant professor at Washington State University’s Department of Entomology/Food and Environmental Quality Laboratory. (David G. Ostrow, MD, PhD - Medical Advisor, cont.)
  • 19. A Medical Cannabis Clinical Model 18 BIBLIOGRAPHY human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem Collaborating Centre: summary of the WHO Collaborating Centre for Neurotrauma Task Force on mild traumatic Therapeutic Use of Marijuana. McFarland & Company
  • 20. A Medical Cannabis Clinical Model 19 PTSD Hill, et al. world trade center attacks. Psychoneuoroendocrinology 38:2952, 2013 Hill, et al. CB1 receptor agonists reverse chronic stress on perseveration behaviors. Neuropsychopharmacology 30:508, 2005 Marsicano, et al. Amygdala CB1 receptors are required for proper extinction of fear memories. Nature 418:530, 2002 Neumeister, et al. CB1 Receptors are unoccupied in brains of PTSD sufferers. Molecular Psychiatry 18:1043, 2013 Trezzu, V., Camplongo, P. disorder. Frontiers in Behavioral Neuroscience, 2013, 7:100 Schier, et al. Cannabidiol, a Cannabis Sativa constituent, as an anxiolytic drug. RBP Psychiatry, Volune 34, Supplement 1, June 2012 Chhatwal, J., et al. Enhancing Cannibinoid Neurotransmission Augments the Extinction of Conditioned Fear. MS 567.
  • 21. A Medical Cannabis Clinical Model 20 Cardio Epilespy Blood Pressure Appel LJ, Champagne CM, Harsha DW, Cooper LS, Obarzanek E, Elmer PJ, Stevens VJ, Vollmer WM, Lin PH, Svetkey LP, et al. Anxiety Alcohol Bi-Polar Neuropathic Pain Anxiety Alzheimer’s Neuropathic Pain TBI Parkinson’s Chronic Pain