Biomatrica Fact Sheet

1. C O R P O R AT E F A C T S H E E T
Ma y 2 0 0 9
C O M PA n y Ov E R v i E w
Biomatrica, an innovative company focused on biostability, offers green technology to stabilize
biological samples such as DNA, RNA, proteins, cells and assays at room temperature.
Biomatrica’s core technology allows researchers and partners to be more efficient and secure
by providing services and room-temperature handling, storage and shipping products that
prevent the degradation of biological samples.
Milestones:
Opportunity
2004
The genomic age and development of high-throughput technologies has • Biomatrica incorporates
resulted in a vast pool of samples that require an integration of storage, • Provisional patent application
organization and analysis. Biological materials are primarily handled and 2005
stored in cold environments (4˚C, -20˚C, -80˚C and liquid nitrogen) which • nitial round of financing
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is costly. Additionally, problems during transport, storage and experimental obtained
• Expansion of patent filed
design arise as even short-term storage of biological material at room
• D Sheriff’s Crime Lab validates
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temperature and repeated freeze/thaw cycles results in sample degradation
DNAstable technology
and loss of activity.
2006
Biomatrica’s technology is poised to create a paradigm shift in the biological • ab and office opened, first
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employee hired
research industry and beyond, allowing the transition from cold to room
• year stability study completed
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temperature storage and handling of biological samples. This will make at SD Sheriff’s Crime Lab with
sample storage and transport more consistent and reliable, ensure an excellent results
ecologically sustainable process and maximize cost-effectiveness. • aunch of DNAstable (DNA
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storage)
Products 2007
Stability Products • aunch of CloneStable (bacterial
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DNA storage)
DNAstable®: Preserve and store genomic and plasmid DNA
• aunch of RNAstable
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at room temperature for long-term storage.
(RNA storage)
RNAstable®: Preserve and store RNA samples at room temperature • elease of SampleWare
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for more than a year. 100% of the RNA can be recovered in 10 minutes Version 2.0
or less. • trategic partnership formed
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with Qiagen GMbH for DNA
CloneStable®: Preserve and store unpurified bacterial genomic and storage
plasmid DNA at room temperature for long-term storage. • iomatrica launches DNA
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CloneStab™: Store and ship live E. coli samples at room temperature. Archive™ with DNA Direct
2008
Assays • aunch of PCRboost
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PCRboost ®: Enhance end-point and reverse transcription-PCR five-fold (amplification enhancer)
or more during amplification of genomic DNA or RNA templates. • elease of SampleWare
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Version 3.0
STRboost™: Improve STR multiplexing performance. • chieved milestones for
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RNAconcentrator™: for concentrating dilute, aqueous RNA samples DNA stabilization in blood
with strategic partner, Qiagen.
to small volumes without sample loss. Second product licensed.
• aunch of CloneStab
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Laboratory Management Software (live bacterial transport)
SampleWare®: An easy-to-use, customizable database to store and • aunch of RNAconcentrator
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organize sample data. This is a tool that links with Biomatrica’s preservation (RNA product line)
and storage platform. • econd round financing
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completed
Biomatrica, Inc. • 5627 Oberlin Drive, Suite 120 • San Diego, CA 92121

2. Market Opportunities
The addressable market size for sample storage is valued at US$34 Billion,
which includes nucleic acid, protein, cell collection and storage as well as Management Team
reagents, vaccine, diagnostic and screening applications. Judy Muller-Cohn, Ph.D.
Founder, CEO
Targets are scientific laboratories throughout the world that encompass
Rolf Muller, Ph.D.
the disciplines of molecular biology, cell biology, genomics, proteomics, Founder, President, CSO
biochemistry and chemistry within universities, research institutes,
Marylinn Munson
biotechnology companies, pharmaceutical companies, medical facilities,
Vice President, Business
and governmental and forensics laboratories. Development
Future products for the storage and transport market will include proteins Martin Latterich, Ph.D.
(US$3 billion), viruses (US$7 billion) and cells (US$5 billion). Senior Director Research and
Development
Biomatrica’s technology can be expanded into a vast array of vertical markets
such as: I) reagents, II) assay and processes, III) sequencing, IV) arrays, Board Of Directors
V) diagnostics, VI) vaccine stabilization.
Joe Markee
Chairman
Technology
Biomatrica offers an innovative platform technology based on a proprietary Francois Ferre
Director
dissolvable sample matrix that “shrink wraps” biological material at room
temperature. Its core technology is adapted from nature, using a molecular John Thompson
mechanism called anhydrobiosis that enables organisms to survive droughts Director
for over one hundred twenty years. A chemical mimic to anhydrobiosis was Judy Muller-Cohn
developed to stabilize biological samples. Founder
Rolf Muller
intellectual Property Founder
• .S. and foreign patent applications filed with priority claim of our core
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technology (dating to 2/04).
Advisory Board
• dditional applications have been filed, directed at broad aspects of
A Francois Ferre
platform technology Founder, Althea Technologies.
• rademark applications filed and issued on the company name and
T
James Gautsch, Ph.D.
key product names. Founder, former CEO of Bio 101,
sold to Qbiogene.
Awards
2006 The Most Innovative Product of the Year in the category of life science Jim Johnson
reagents and tools for the first products from Connect, a globally recognized Former VP of Worldwide
Commercial Operations for
public benefits organization fostering entrepreneurship in San Diego. Invitrogen and Novex
National Institute of Justice Grant to develop a Crime Scene Collection Kit for DNA John H. Crowe, Ph.D.
Professor Emeritus UC Davis.
Partnerships, Collaborations and Licensing Founder and former Director
“The Institute of Biostability”
In 2007 Biomatrica signed a license and supply partnership with Qiagen,the
worldwide leader in DNA extraction and purification reagents for the DNA John Elder, Ph.D.
SampleGard® and the DNA portion of the SampleMatrix technology for Professor,
distribution to end-users. Also in 2007, Biomatrica entered into a partnership The Scripps Research Institute
with DNA Direct to produce the DNA Archive™ which is sold into the consumer John Thompson
market for personalized DNA banking. Biomatrica has collaborated with Former Exec. VP of Corporate
institutions such as the University of California system, the Scripps Research Strategy for Invitrogen
Institute, the U.S. Navy, CalState LA, and the National Institute of Justice. Paul Bremner
Founder and Former CEO,
Financial VASci Software Company
As a privately held company, Biomatrica commenced product sales in 2006 Sheldon Cohn, J.D., M.B.A.
and partnerships in 2007. Profitability and a positive cash flow are projected CEO Budget National Finance
in 2009 based on a product-based sales strategy and an active new Sheldon Engelhorn
product release schedule for the next 5-7 years. Biomatrica has a worldwide Founder of Novex,
distribution network covering Canada, Europe, and Asia. sold to Invitrogen
Riccardo Pigliucci
Contact Former President Perkin Elmer
Marylinn Munson, Biomatrica
Thomas Fitting, Ph.D., J.D.
Vice President, Business Development
Chief Patent Counsel,
Tel: (858) 550-0308 ext. 233 Cell: (858) 336-1492 The Scripps Research Institute
Email: mmunson@biomatrica.com Web: www.biomatrica.com
©2009 Biomatrica, Inc. All rights reserved.