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Category : Pharma & Healthcare
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Introduction to Report
 Launch Date: June 20, 2014
 Number of Pages: 134
 Geography Coverage: Global
 Available Format: PDF
Price For Single User License: USD 5,995
Price For Site License: USD 11,990
Price For Global User License: USD 17,985
Delivery Time: Within 24 Hours (During Working Days)

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About the Report
Amyotrophic lateral sclerosis (ALS) is a rare, but fatal, motor
neuron disease (MND) characterized by axonal degeneration and
progressive loss of motor neurons. ALS affects both the upper
(brain to spinal cord) and lower (brain stem to muscle tissue)
motor neurons, gradually reducing a patient’s ability to initiate
and control muscle movement. Muscle atrophy, starting in the
periphery (arms and legs), ultimately leads to complete paralysis
after several years of progressive worsening of muscle strength.
Respiratory failure is the most common cause of death, as
smooth muscle function becomes affected when the disease is in
its final stages.
The progressively degenerative course of the condition is a great
burden for both patients and caregivers, as well as for society.
ALS usually affects people age =40 years, and has a worldwide
incidence of about two cases per 100,000 population, and a
prevalence ranging between four and seven cases per 100,000.

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Research Findings
Patent Expiration of Rilutek to Cause Negative Growth in
Amyotrophic Lateral Sclerosis Treatment Market by 2018
The amyotrophic lateral sclerosis (ALS) treatment market value
will decline from $64 million in 2013 to $38 million by 2018, at a
negative Compound Annual Growth Rate (CAGR) of 10.05%,
according to research and consulting firm by Publisher.
The company’s latest report states that the largest factor in this
decline, which will occur over seven major markets (7MM: the
US, France, Germany, Italy, Spain, the UK, and Japan), will be the
patent expiration of Rilutek (riluzole), the only approved therapy
for ALS.
As a consequence, Publisher forecasts that the ALS treatment
market in the US is set to suffer a substantial reduction in sales
over the forecast period, from $38 million in 2013 to $16 million
by 2020, at a negative CAGR of 16.10%.

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Scope
Overview of ALS, including etiology and pathophysiology,
general symptoms, quality of life, country-specific treatment
recommendations and epidemiologic data.
Annualized ALS market revenue, annual cost of treatment and
usage patterns from 2013 and forecast for five years to 2018.
Key topics covered include unmet needs analysis, research and
development strategies, pipeline assessment, and pipeline
valuation analysis for the ALS market.
Pipeline valuation analysis: clinical and commercial
benchmarking of AB Science’s AB-1010 (masitinib), Cytokinetics’
CK-2017357 (tirasemtiv), Mitsubishi Tanabe’s Radicut
(edaravone), Eisai’s Methycobal (mecobalamin), and Orphazyme
ApS’ arimoclomol.
Assessment of the current and future market competition in
the global ALS drug market. Insightful review of the key industry
and governmental drivers, restraints and challenges. Each trend
is independently researched to provide qualitative analysis of its
implications.

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Report Coverage
1. Table of Contents
2. Introduction
3. Disease Overview
4. Epidemiology
5. Current Treatment Options
6. Unmet Needs Assessment and Opportunity Analysis
7. Research and Development Strategies
8. Pipeline Assessment
9. Pipeline Valuation Analysis
10.Appendix
For more details regarding Report coverage see the last slide
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About Market Research Reports, Inc.
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