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ENDING THE GLOBAL REPRODUCIBILITY CRISIS IN MEDICAL RESEARCH
- 1. 1 ENDING THE GLOBAL REPRODUCIBILITY CRISIS IN MEDICAL RESEARCH + MYR support@myire.com - 707 356 9473
- 2. WHAT’S IN A NAME? 2 MyIRE stands for My Integrated Research Environment The term “Integrated Research Environment” borrows from the computer scientist world where an “integrated development environment” allows developers from all over the world to rapidly create software using common tools. “IRE” represents the frustration that researchers feel when conducting research with the myriad of disconnected tools required.
- 3. Empower Thousands of Doctors Impact Millions of Lives Save Billions of Dollars WHO WE ARE 3 MyIRE believes that easy to use scientific platforms revolutionize the medical discovery process Easy to Use Doctors focus on research instead of IT management Increases Research Integrity More uses impacts more lives Streamlines Research Increases research ROI
- 4. WHY WE ALL NEED MYIRE 4 https://xkcd.com/242/ https://www.nature.com/news/1-500-scientists-lift-the-lid-on-reproducibility-1.19970 Your life depends on your doctor’s advice. We all get sick, and when we do, we turn to our doctor for their expert opinion on how to navigate the available treatment options Your doctor depends on medical research. Every care choice and piece of advice your doctor provides is based on medical experiments. These experiments are expensive and time consuming for doctors, patients, and industry. Most medical research is not reproducible Researchers repeat experiments to verify their accuracy. Unfortunately, researchers often get different results when they repeat experiments. This means your doctor’s expert opinion could be based on faulty evidence.
- 5. REMEMBER THE TELEPHONE GAME? 5 The message breaks down as it is passed from step to step.
- 6. RESEARCH PROJECTS ARE A TELEPHONE GAME OF TOOLS 6 The same thing happens in science. The message breaks down as the researcher moves data from one disparate tool to the other.
- 7. 7 OUR CUSTOMERS HATE THE TELEPHONE GAME “In simple terms, the software wasn't designed for us. Software that would actually look at our workflow and respond to our needs would be useful. But in virtually every product I've seen, the investigator is an afterthought not central to the design. The software isn't focused on the way that physicians, coordinators and clinicians work. There is nothing about it that is investigator friendly” Michael Koren, M.D. CEO, Jacksonville Center for Clinical Research The CenterWatch Monthly, May 2016 Today, too many tools are inconsistently applied amongst too many departments that don’t meet the needs of today’s investigators.
- 8. Scientific Idea Reproducible Reusable Research Hypothesis Generation Study Design Budget Creation Study Operations Enrollment & Retention Publication Creation MyIRE MyIRE Provides an Integrated, End-to-End, Turn-Key Solution that Takes a Research Question from Hypothesis to Publication in a Reproducible Way Data Management & Analytics 8 MYIRE ENDS THE TELEPHONE GAME DeliverableDoctor “MyIRE is a revolutionary platform that provides an innovative method to manage all the operational components of a research study allowing the research team to focus on the science.” -- Associate Professor of Neurological Surgery, Feinberg School of Medicine
- 9. MYIRE’S REPRODUCIBLE BLOCKCHAIN MODEL Doctors choose from interoperable modules to suit their needs. Hypatia Hypothesis Generation MyIRE can be deployed on premise, in our HIPAA compliant secure cloud or in a distributed model. MyIRE can interact with other solutions with our interoperable APIs. Alexander Study Design Budget Creation Hooke Study Operations Enrollment & Retention Data Management & Analytics Gutenberg Reporting Publication Creation Agora Research Exchange & Market The MyIRE Platform Consists of Integrated and Interoperable Modules That Enable an Investigator to Conduct an Entire Clinical Research Trial from Beginning to End. The modules link together via blockchain to form reproducible projects.
- 10. BUILT ON BLOCKCHAIN 10 Blockchain ensures trust, transparency, and consistent communication via cryptography, ensuring the highest level of integrity
- 11. THE MYR TOKEN 11 To use the MyIRE platform, users must purchase MYR tokens. Prospective users will only be able to purchase the products, services, and modules offered by or through the MyIRE platform with MYR tokens. Moreover, only paying clients of MyIRE will have access to the ecosystem.
- 12. THE MYR VALUE PROPOSTION 12 § In order to power the MyIRE platform for the conduct of reproducible research, a native cryptocurrency, the MyIRE (“MYR”) token, will be created and distributed to network participants. § The MYR token will allow value created in the system to be captured by the system itself. Just as almost all countries have their own currency, requiring transactions on the MyIRE platform to be in MYR will set up incentives to remain in the system. § By requiring that transactions use MYR, participants will become claim holders on the system, which we believe will generate the same incentives that have helped ecosystems like Ethereum (and many so-called “alt-coins”) explode into active and diverse communities.
- 13. HOW MYR BENEFITS MYIRE 13 Increase in Offered Products and Services • We believe the value of the MYR token will increase as the number and value of products offered by or through the MyIRE platform increases. • We believe that more offered products and services will increase demand for access to the MyIRE platform, thereby increasing demand for MYR tokens. Increase in Liquidity • We believe that more participants in the MyIRE ecosystem will increase the liquidity of the MYR token. • We believe that a more liquid token can lead to more stability and higher value. Transaction Fees • MYR will be a revenue generator for MyIRE, Inc. In addition to the subscriptions fees MyIRE will collect from users of the platform, we plan to charge a percentage-based transaction fee – to be paid with MYR tokens - on each purchase between third parties within the MyIRE ecosystem • We believe this fee will create a recurring and increasing revenue stream for MyIRE, Inc. and also increase demand and value for MYR tokens.
- 14. 14 MYIRE’S REVENUE MODEL Project Solutions For Investigators Proposal Submission Research Execution Access to Marketplaces Setup Fee + Monthly Subscription Enterprise Solutions For Pharma Grant Management Research Oversight Setup Fee + Annual Subscription Fee Marketplaces For Everyone Facilitates exchange of intellectual property and professional services Percent of Transaction Cost • MyIRE has separate pricing models that meet the different needs of the individual investigator; and the pharmaceutical company or research institution. • And, the MYR ecosystem will provide an innovative marketplace for the exchange of information and services.
- 15. 15 EXPERTS AND ADVISORS Mark Graves Jr. Founder/CEO/CTO 14 yrs Research IT experience 2 yrs Feinberg Medical School Massimo DiPierro, PhD DePaul CS Professor 25 yrs Research IT experience Former Google Consultant Mark Graves Sr., MD Assoc. Prof. of Medicine Assoc. Prof. of Radiology 100+ Clinical Trials Michael Harbin Orbitz, Co-Founder 20+ years technical operations 5 successful exits David Giljohann, PhD Exicure - Founder/CEO (2017 IPO) Funded $13.6M by Gates Foundation $790M Research Collaboration Mark Schindel Private equity background 30+ years finance experience CFO for multiple businesses Gregory Folz, CCRP 20+ yrs Intl. Research Management & Sales $85M in Clinical Investigator Grants 800+ Clinical Trials We Have a Great Team to Support and Guide our Growth!