1. PUBLICATIONS/PATENTS : Contributor on 22 Patents , 1 poster in ACS national meeting
and 5 Papers
1. Beard, Richard L.; Yuan, Haiqing; Donello, John E.; Liu, Xiaoxia; Duong, Tien;.6-
SUBSTITUTED INDOLE-3-CARBOXYLIC ACID AMIDE COMPOUNDS
HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST
BIOLOGICAL ACTIVITY. Patent Number:US2008171772 A1 20080717.
2. Beard, Richard L.; Yuan, Haiqing; Donello, John E.; Liu, Xiaoxia.
HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-
PHOSPHATE (S1P) RECEPTOR AGONIST AND/OR ANTAGONIST
BIOLOGICAL ACTIVITY. Patent Number:WO2008030843 A1 20080313.
3. Beard, Richard L.; Yuan, Haiqing; Donello, John E.; Liu, Xiaoxia.
HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-
PHOSPHATE (S1P) RECEPTOR AGONIST BIOLOGICAL ACTIVITY. Patent
Number: US7728014 B2 20100601.
4. Beard, Richard L.; Yuan, Haiqing; Donello, John E.; Liu, Xiaoxia.
HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-
PHOSPHATE (S1P) RECEPTOR AGONIST BIOLOGICAL ACTIVITY. Patent
Number: WO2008030838 A2 20080313.
5. Beard, Richard L.; Donello, John E.; Yuan, Haiqing; Liu, Xiaoxia; Duong, Tien; Colon,
Diana F.; Hu, Yihui. Preparation of indole-3-carboxylic acid amides, esters,
thioamides, and thiol esters as sphingosine-1-phosphate (S1P) receptor agonists or
antagonists. Patent Number: WO 2007095561 A2 20070823 .
6. Beard, Richard L.; Donello, John E.; Yuan, Haiqing; Colon, Diana F.; Duong, Tien;
Liu, Xiaoxia; Hu, Yihui. Preparation of indole-3-carboxylic acid amides, esters,
thioamides, and thiol esters as sphingosine-1-phosphate (S1P) receptor agonists or
antagonists. Patent Number: US7737173 B2 20100615.
7. Tsang, Kwok Yin; Sinha, Santosh; Liu, Xiaoxia; Bhat, Smita; Chandraratna, Roshantha
A. Disubstitutedchalcone oximes as selective agonists of RAR retinoid receptors
Patent Number: US7476673 B2 20090113.
8. Tsang, Kwok Yin; Sinha, Santosh; Liu, Xiaoxia; Bhat, Smita; Chandraratna, Roshantha
A. Disubstitutedchalcone oximes having RARy retinoid receptor antagonist
activity Patent Number: US7253319 B2 20070807.
9. Vasudevan, Jayasree; Yang, Rong; Wang, Liming; Liu, Xiaoxia; Tsang, Kwok Yin; Li,
Ling; Takeuchi, Janet A.; Vu, Thong; Beard, Richard L.; Bhat, Smita; Chandraratna,
Roshantha A. Methods for treating retinoid responsive disorders using selective
inhibitors of CYP26A and CYP26B Patent Number: US7468391 B2 20081223.
10. Vasudevan, Jayasree; Wang, Liming; Liu, Xiaoxia; Tsang, Kwok Yin; Li, Ling;
Takeuchi, Janet A.; Vu, Thong; Beard, Richard L.; Bhat, Smita; Vuligonda, Vidyasagar;

2. Chandraratna, Roshantha A. Compounds having selective cytochrome P450RAI-1
or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining
the same Patent Number: US7226951 B2 20070605
11. Beard, Richard L.; Duong, Tien T.; Takeuchi, Janet A.; Li, Ling; Tsang, Kwok Yin; Liu,
Xiaoxia;Vasudevan, Jayasree; Wang, Liming; Sinha, Santosh C.; Yuan, Haiqing;
Chandraratna, Roshantha A. 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and
7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having
serum glucose reducing activity Patent Number: US6887896 B1 20050503.
12. Tsang, Kwok Yin; Sinha, Santosh; Liu, Xiaoxia; Bhat, Smita; Chandraratna, Roshantha
A. 3-(C5-14ALKYL-2-OXO-1,2,3,4-TETRAHYDRO-QUINOLIN-6-YL)-3-OXO-
PROPENYL]-PHENYL AND [3-(C5-14ALKYL-2-OXO-1,2,3,4- TETRAHYDRO-
QUINOLIN-6-YL)-3-OXO-PROPENYL]-HETEROARYL DERIVATIVES
HAVING ANTI-TUMOR ACTIVITY Patent Number: US6683092 B120040127.
13. Vasudevan, Jayasree; Wang, Liming; Liu, Xiaoxia; Tsang, Kwok Yin; Yuan,Yang-Dar;
Chandraratna, Roshantha A. 4-[(8-Ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-
chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-
chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome
P450RAI inhibitory activity Patent Number: US6740676 B2 20040525.
14. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS
CHEMOKINE RECEPTOR MODULATORSPatent Number: US8,580,779, US
2014/0221351 A1, US8,729,066
15. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR
MODULATORSPatent Number: US8450367.
16. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. BENZOISOTHIAZOL-3(1H)-ONE-5-SULFONYL DERIVATIVES
AS CHEMOKINE RECEPTOR MODULATORSPatent Number: US8,524,745.
17. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. PHOSPHOROUS DERIVATIVES AS CHEMOKINE RECEPTORS
MODULATORSPatent Number: US8,518,913.
18. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. BENZOISOTHIAZOL-2-SULFONAMIDES DERIVATIVES AS
CHEMOKINE RECEPTOR MODULATORSPatent Number: US20130231338.
19. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. BENZOISOTHIAZOL-2-SULFONAMIDES PYRIDINE
DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORSPatent Number:
US2013/0231339 A1; US8,815,915 B2

3. 20. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. PYRIDINYL AND PYRIMIDINYL SULFONAMIDE DERIVATIVES
AS CHEMOKINE RECEPTOR MODULATORSPatent Number: US 2014/0275132
A1, WO2014159657.
21. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia;. BENZOTHIOPHENE
SULFONAMIDES AND THEIR USE AS CHEMOKINE RECEPTOR
MODULATORSPatent Number: PENDING.
22. Yuan, Haiqing; Beard, Richard L.; Liu, Xiaoxia; Donello, John E; VeenaViswanath;
Make Garst. SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR
MODULATORSPatent Number: US 2013/0190338 A1; US 8,822,530 B2
23. “Discovery, optimization, and structure-activity relationship of a novel series of indole-
3-carboxylamide S1P3 selective antagonists”, 247th ACS National Meeting Poster, 2014,
Colorado
24. “The study of Continuous Monitoring of Solar Ultraviolet Radiation Using
Polyethylene Sheet.”Polymeric Materials Science and Engineering, 1993, 9, 4
25. “The Effect of the Aging Surface-layer of r-PVC on its Mechanical Behavior”
Polymeric Materials Science and Engineering, 1992, 8, 3
26. “Evaluations on Aggravations of Plastics Pipes for Transport of Gas Over Long
Periods”, Engineering Plastics Application, 1993, 21, 3
27. “Studies on Out Door Service Endurance of Modified Rigid PVC Profile for Door and
Window Frame”, China Plastics, 1993, 7, 3
28. “The Degrading Behavior of Photo-Degradable Polyethylene Films in Out-door
Exposure”, China Plastics, 1992, 6, 3