Drug Databases

•Download as PPTX, PDF•

0 likes•435 views

KazimZargham

Databases for chemical information

Health & Medicine

DATABASE FOR CHEMICAL
INFORMATION
M. Kazim Zargaham

INTENDED LEARNING OBJECTIVES
By the end of the theme, learner would be able to:
Cognitive:
• List different databases available for drugs, chemical information
and research.
• Explain the use of selected databases related to drugs, chemical
information and research.
Psychomotor:
• Demonstrate the use of selected databases related to drugs,
chemical information and research
• Download and save the information available on selected
databases related to drugs, chemical information and research.

DATABASE
• A collection of logically related information organized so that it
can be easily accessible, managed, and updated.

DATABASE FOR CHEMICAL
INFORMATION
• PubChem
• DrugBank
• ZINC
• ChEMBL
• Chemspider
• KEGG DRUG Database
Reference: https://www.click2drug.org/index.php#Databases

WHAT IS PUBCHEM?
• PubChem is the world's largest collection of freely
accessible chemical information.
• Search chemicals by name, molecular formula,
structure, and other identifiers.
• Find chemical and physical properties, biological
activities, safety and toxicity information, patents,
literature citations and more.

DRUGBANK
• DrugBank Online is a comprehensive, free-to-access (with the
latest update, it requires subscription now), online database
containing information on drugs and drug targets.
• As both a bioinformatics and a cheminformatics resource, we
combine detailed drug (i.e. chemical, pharmacological and
pharmaceutical) data with comprehensive drug target (i.e.
sequence, structure, and pathway) information.
• DrugBank Online is widely used by the drug industry, medicinal
chemists, pharmacists, physicians, students and the general
public. Because of its broad scope, comprehensive referencing,
and detailed data descriptions, DrugBank is enabling major
advancements across the data-driven medicine industry.

CHEMBL
• ChEMBL is a manually curated database of bioactive molecules
with drug-like properties. It brings together chemical, bioactivity
and genomic data to aid the translation of genomic information
into effective new drugs.

ZINC15
• A free database of commercially-available compounds for virtual
screening.
• ZINC contains over 230 million purchasable compounds in
ready-to-dock, 3D formats.
• ZINC also contains over 750 million purchasable compounds you
can search for analogs in under a minute.

What's hot

Structure based drug design

ADAM S

Drug and Chemical Databases 2018 - Drug Discovery

Girinath Pillai

Computer aided drug design(CADD)

Sameh Abdel-ghany

Pharmacogenomics

Sirisha Annavarapu

Computer aided drug design

N K

Pharmacophore mapping

GamitKinjal

Drug Designing

ZainabSaif

Drug properties (ADMET) prediction using AI

IndrajeetKumar124

OVERVIEW OF MODERN DRUG DISCOVERY PROCESS

Sweety gupta

Protocol ppt

aishuanju

MOLECULAR DOCKING.pptx

E Poovarasan

Artificial intelligence in drug discovery

RAVINDRABABUKOPPERA

Drug Discovery Process by Kashikant Yadav

Kashikant Yadav

1. Unit I - new drug discovery and development.

Audumbar Mali

Homology modelling

Ayesha Choudhury

Recombinant DNA Technology and Drug Discovery

Divya V

Target identification

Sachin Jangra

Pharmaogenomics

FarazaJaved

Detection, reporting and management of adverse events

Katla Swapna

Active and passive survillance

Ramavath Aruna

What's hot (20)

Structure based drug design

Drug and Chemical Databases 2018 - Drug Discovery

Computer aided drug design(CADD)

Pharmacogenomics

Computer aided drug design

Pharmacophore mapping

Drug Designing

Drug properties (ADMET) prediction using AI

OVERVIEW OF MODERN DRUG DISCOVERY PROCESS

Protocol ppt

MOLECULAR DOCKING.pptx

Artificial intelligence in drug discovery

Drug Discovery Process by Kashikant Yadav

1. Unit I - new drug discovery and development.

Homology modelling

Recombinant DNA Technology and Drug Discovery

Target identification

Pharmaogenomics

Detection, reporting and management of adverse events

Active and passive survillance

Similar to Drug Databases

Mustafa kamal drugs database (assignment 3)

Mustafa Kamal A. Khan

Pubchem

samantlalit

Web-based technologies coupled with a drive for improved communication between scientists have resulted in the proliferation of scientific opinion, data and knowledge at an ever-increasing rate. The increasing array of chemistry-related computer-based resources now available provides chemists with a direct path to the discovery of information, once previously accessed via library services and limited to commercial and costly resources. We propose that preclinical absorption, distribution, metabolism, excretion and toxicity data as well as pharmacokinetic properties from studies published in the literature (which use animal or human tissues in vitro or from in vivo studies) are precompetitive in nature and should be freely available on the web. This could be made possible by curating the literature and patents, data donations from pharmaceutical companies and by expanding the currently freely available ChemSpider database of over 21 million molecules with physicochemical properties. This will require linkage to PubMed, PubChem and Wikipedia as well as other frequently used public databases that are currently used, mining the full text publications to extract the pertinent experimental data. These data will need to be extracted using automated and manual methods, cleaned and then published to the ChemSpider or other database such that it will be freely available to the biomedical research and clinical communities. The value of the data being accessible will improve development of drug molecules with good ADME/Tox properties, facilitate computational model building for these properties and enable researchers to not repeat the failures of past drug discovery studies.

Precompetitive preclinical ADME/tox data and set it free on the web to facili...

US Environmental Protection Agency (EPA), Center for Computational Toxicology and Exposure

An introduction to the Linked Structured Product Label (LinkedSPL) resource for the W3C Health Care and Life Sciences Linking Open Drug Data task force. LinkeSPLs (purl.org/net/nlprepository/linkedSPLs) publishes selected sections of FDA-approved drug package inserts from DailyMed for use by NLP and Semantic Web researchers. Currently, only data from the product labels of prescription drugs is provided. This site's SPL data is updated weekly and all SPLs retain DailyMed versioning data so that researchers can record the provenance of the text and sections they work with. LinkedSPLs is provided as a service as part of the Drug Interaction Knowledge Base (DIKB) project

Linked-spls-initial-hcls-presentation-06082012

Richard Boyce, PhD

INFORMATICS 2.pptx

ramadevi824914

INFORMATICS 2.pptx

Oramadevi1

Presented at the Joint Statistical Meetings (JSM) 2020 (virtual) on August 3, 2020. ==== Abstract ==== The idea of “big data” has recently been drawing much attention of the scientific community as well as the general public. An example of big data in Chemistry is the data contained in PubChem, which is a public database of chemical substance descriptions and their biological activities at the National Institutes of Health. PubChem is a sizeable system with 235 million depositor-provided substance descriptions, 96 million unique chemical structures, 1.1 million biological assays, and 268 million biological activity result outcomes. It also contains significant amounts of scientific research data and the inter-relationships between chemicals, proteins, genes, scientific literature, patents and more. PubChem resources have been used in many studies for developing bioactivity and toxicity prediction models, discovering multi-target ligands, and identifying new macromolecule targets of compounds (for drug-repurposing or off-target side effect prediction). This presentation provides an overview of how PubChem’s data, tools, and services can be used for bioassay data analysis and virtual screening (VS) and discusses important aspects of exploiting PubChem for drug discovery.

PubChem: a public chemical information resource for big data chemistry

Sunghwan Kim

Presented online at KSEA - Virginia Washington Metro Regional Conference 2020 (VWMRC 2020) (May 9, 2020) ==== Abstract ==== PubChem (https://pubchem.ncbi.nlm.nih.gov) is a popular chemical information resource, visited by millions of unique users per month. It contains chemical data from more than 700 data sources and disseminates these data to the public free of charge. Arguably, it is the largest source of publicly available chemical information, containing more than 250 million depositor-provided substance descriptions, 100 million unique chemical structures, and 260 million bioactivity outcomes from one million assays covering around ten thousand unique protein target sequences. This presentation provides an overview of PubChem’s data, tools, and services useful for drug discovery. The immense quantity of bioactivity data in PubChem can be used to develop computational models to predict bioactivities of small molecules. While these data are primarily generated from high-throughput screening (HTS), they also include a substantial amount of bioactivity information extracted from peer-reviewed journal articles. In addition, through data integration with other databases, PubChem has a wide range of annotations useful for drug discovery, including pharmacology, toxicology, drug target, metabolism, chemical vendors, scientific articles, patents, and many others. PubChem supports various types of chemical structure searches, including identity, 2-D and 3-D similarity, substructure, superstructure, and molecular formula. It also provides multiple programmatic access routes, including E-Utilities, Power User Gateway (PUG), PUG-SOAP, PUG-REST, and PUG-View, allowing one to build an automated workflow that takes advantage of information contained in PubChem. In addition, through PubChemRDF, users can integrate PubChem data with their own.

Exploiting PubChem for Drug Discovery

Sunghwan Kim

Cheminformatics Education with PubChem

Sunghwan Kim

This presentation was made to the University of North Carolina in Chapel Hill on 9/20/21. The presentation was a general introduction to cheminformatics prior to how to navigate the Dashboard. • An introduction to the dashboard • Substances vs structures • Structure formats for data exchange and connectivity (SMILES, InChIs, molfiles) • Identifiers – CASRN, chemical names, systematic names • Data curation approaches: substance-structure ambiguity • ChemReg: substance registration • Data gathering for systematic reviews • Curated lists • Properties/Fate and Transport • Access to Exposure Data • Hazard data in the dashboard – ToxVal data (sourced from >40 databases, >50,000 chemicals, >900,000 data points) • The Executive Summary of data • Single chemical searches vs Batch searches

Introduction to Cheminformatics: Accessing data through the CompTox Chemicals...

US Environmental Protection Agency (EPA), Center for Computational Toxicology and Exposure

Library resources for clinical faculty

Kristin Kroger

In recent years the Royal Society of Chemistry has become known for our development of freely accessible data platforms including ChemSpider, ChemSpider Reactions and our new chemistry data repository. In order to support drug discovery RSC participates in a number of projects including the Open PHACTS semantic web project, the PharmaSea natural products discovery project and the Open Source Drug Discovery project in collaboration with a team in India. Our most recent developments include extending our efforts to support neglected diseases by the provision of high quality datasets resulting from our curation efforts to support modeling, the delivery of enhanced application programming interfaces to allow open source drug discovery teams to both source and deposit data from our chemistry databases and the provision of a micropublishing platform to report on various aspects of work supporting neglected disease drug discovery. This presentation will review our existing efforts and our plans for extended development.

Royal society of chemistry developments to support open drug discovery

Ken Karapetyan

Royal society of chemistry developments to support open drug discovery

US Environmental Protection Agency (EPA), Center for Computational Toxicology and Exposure

In this lecture, I provide an overview on how computers can be instrumental in drug discovery efforts. Topics covered includes: big data as a result of omics effort; bioinformatics; cheminformatics; biological space; chemical space; how computers particularly machine learning (and data science) can be applied in the context of drug discovery. A video of this lecture is also provided on the "Data Professor" YouTube channel available at http://bit.ly/dataprofessor If you are fascinated about data science, it would mean the world to me if you would consider subscribing to this channel (by clicking the link below): http://bit.ly/dataprofessor

Computational Drug Discovery: Machine Learning for Making Sense of Big Data i...

Chanin Nantasenamat

Anticancer bioscience

JingZhang345

Mass spectrometry analyses at the US-EPA, especially non-targeted analysis studies, are highly dependent on the cheminformatics efforts which have been underway within the agency for almost a decade. These research efforts have resulted in a rich data infrastructure based on the DSSTox database, data integration approaches based on a structure standardization approach to produce “MS-ready” structures, and a number of supporting data types to facilitate ranking of non-targeted analysis candidates. This presentation will provide an overview of all tools in development and the integrated nature of the applications based on the underlying chemistry data. This includes the development of the underlying chemistry database of >1.2 million chemical substances (DSSTox), approaches to structure standardization to facilitate structure-substance mapping, development of a spectral database of >150,000 spectra for >25,000 chemicals, a database of >3000 analytical methods, prediction models for LCMS amenability, and an application for the profiling of toxicity hazards for batches of chemical substances. This abstract does not necessarily represent the views or policies of the U.S. Environmental Protection Agency.

Cheminformatics tools and chemistry data underpinning mass spectrometry analy...

US Environmental Protection Agency (EPA), Center for Computational Toxicology and Exposure

Library resources for clinical faculty

Kristin Kroger

Extending the "Web of Drug Identity" with knowledge extracted from United Sta...

Richard Boyce, PhD

Role of bioinformatics in drug designing

W Roseybala Devi

HPD library resources for clinical affiliates

jsarpy

Similar to Drug Databases (20)

Mustafa kamal drugs database (assignment 3)

Pubchem

Precompetitive preclinical ADME/tox data and set it free on the web to facili...

Linked-spls-initial-hcls-presentation-06082012

INFORMATICS 2.pptx

PubChem: a public chemical information resource for big data chemistry

Exploiting PubChem for Drug Discovery

Cheminformatics Education with PubChem

Introduction to Cheminformatics: Accessing data through the CompTox Chemicals...

Library resources for clinical faculty

Royal society of chemistry developments to support open drug discovery

Computational Drug Discovery: Machine Learning for Making Sense of Big Data i...

Anticancer bioscience

Cheminformatics tools and chemistry data underpinning mass spectrometry analy...

Library resources for clinical faculty

Extending the "Web of Drug Identity" with knowledge extracted from United Sta...

Role of bioinformatics in drug designing

HPD library resources for clinical affiliates

Recently uploaded

VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋 Call Mr Chirag Ji +91-7877925207 NORTH/SOUTH INDIANS HIGH CLASS MODELS/COLLEGE GIRLS/ HOUSEWIVES/BODY TO BODY MASSAGE, SANDWICH MASSAGE, SHOWER BATHING, BLOW JOB, LICKING, FRONT AND BACK SHOT, RUBBING, KISSING SMOOCHING ETC ETC... UNLIMITED FUN Call 24/7. Your assistance for your service... ☛ ✔✔ secure✔✔ 100% safe ✔✔ Vip Callgirl Service offers you the most beautiful High Profile sexy independent female Escorts in genuine ✔✔✔ To enjoy with hot and sexy girls ✔✔✔ A03524SW ★providing:- • Models • vip Models • Russian Models • Foreigner Models • TV Actress and Celebrities • Receptionist • Air Hostess • Call Center Working Girls/Women • Hi-Tech Co. Girls/Women • Housewife • Collage Going Girls. • Travelling Escorts. • Ramp-models • Foreigner And Many More.. ★OUR BEST SERVICES: - FOR BOOKING ★ A-Level (5 star escort) ★ Strip-tease ★ BBBJ (Bareback Blowjob)

VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋

TANUJA PANDEY

Call Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service Available Call Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Jabalpur Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Jabalpur Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Jabalpur Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service Available

Dipal Arora

Call Girls Bareilly Just Call 8250077686 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Bareilly Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Bareilly Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Bareilly Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Bareilly Just Call 8250077686 Top Class Call Girl Service Available

Dipal Arora

Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl In 5 Star Hotel Service Available Booking Contact Details WhatsApp Chat: +91-8250192130 Hyderabad Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Hyderabad understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more. 29-Apr(Ast)

Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...

astropune

Call Girls Agra Just Call 8250077686 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Agra Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Agra Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Agra Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Agra Just Call 8250077686 Top Class Call Girl Service Available

Dipal Arora

Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 Star Hotel Service Available Booking Contact Details WhatsApp Chat: +91-8617370543 Patna Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Patna understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more.

Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...

Dipal Arora

Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Cuttack Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Cuttack Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Cuttack Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available

Dipal Arora

(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent CALL GIRLS Available for Sex Shot FULL Night Navi Mumbai ESCORTS Booking Contact Details WhatsApp Chat: +91-9920874524 24/7 Hotel service is offered 💐 every region in the VIP star category Genuine service with regular price guarantees and happiness for hotel outcall and incall services High-end Escorts Hi-fi foreigners model best n real service call; Russian new model actress Airhostess sexy girls uncovered service with AC rooms 5 star category Hotels call n Whatsapp Local college girls cheap escorts VIP Callgirl High class models from North and South India, college girls, housewives, body to body massage, sandwich massage, shower bathers, blow job painters, licking, front and rear shooters, smooching, rubbing, and more... ENDLESS FUN ✔ Full on escorts Service by High Profile ✔✔ Top North Indian Models ✔✔ Air-Hostess ✔✔ Foreigner,Russian ✔✔ College Girls ✔✔ Students ✔✔ Corporate Ladies ✔✔ MBA Students and Much More.... Our Services 🙏🙏🙏🙏🙏

(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...

Taniya Sharma

Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Rajasthan Booking Details Are here 05-May-2024( Mj) Click On WhatsApp Chat +91-8445551418 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Ra...

parulsinha

VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Their Home & Hotels Why you Choose Us- +91-7877925207 Hyderabad Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable I Have Extremely Beautiful Broad Minded Cute Sexy & Hot Call Girls and Escorts, We Are Located in 3* 4* 5* Hotels. Safe & Secure High Class Services Affordable Rate 100% Satisfaction, Unlimited Enjoyment. Any Time for Model/Teens Escort in Delhi High class luxury and premium escorts agency. ★ CALL US High Class Luxury and Premium Escort Service We Provide Well Educated,Royal Class Female,High-Class Escort Service Offering a Top High Class Escort Service In The & Several Nearby All Places of . A300424ST ★ To Enjoy With Hot and Sexy Girls . ★ We Are Providing :- • 3* 5* 7*Hotels Service • Hygienic Full AC Neat and Clean Rooms Avail. • Daily New Escorts Staff Available • Minimum to Maximum Range Available. HOT⇄ 7877925207 Mr Chirag ji Our escort service •BJ (Blowjob) •FK (French kissing) •Kissing with tongue •O-Level (Oral sex) •Long Silky Brown Hair •69 (69 sex) •A-Level (5 start Escort) •Dating

VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...

jageshsingh5554

Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 9833325238 Nargish Khan Booking Contact Details WhatsApp Chat: +91-9833325238 Mumbai Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable. Independent Escorts Mumbai understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more. 06-May 24 (Smt)

Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...

Ishani Gupta

Call Girls Guntur Just Call 8250077686 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Guntur Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Guntur Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Guntur Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Guntur Just Call 8250077686 Top Class Call Girl Service Available

Dipal Arora

(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Celebrity for 5* Hotels Booking Details Are here 05-May-2024( Mj) Click On WhatsApp Chat +91-8445551418 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...

parulsinha

Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Aurangabad Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Aurangabad Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Aurangabad Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available

Dipal Arora

Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine Sex Service At Affordable Rate Booking Contact Details WhatsApp Chat: +91-9332606886 Hyderabad Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Hyderabad understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more. 02-May(Ast)

Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...

chandars293

Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Gwalior Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Gwalior Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Gwalior Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available

Dipal Arora

Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent High Profile Call Girl 24×7 Booking Contact Details WhatsApp Chat: +91-9930245274 Mumbai Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable. Independent Escorts Mumbai understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more. 29-04-24 (Smt)

Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...

Call Girls in Nagpur High Profile

Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Ludhiana Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Ludhiana Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Ludhiana Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available

Dipal Arora

♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl 100% Genuine Please Contact Me Booking Contact Details WhatsApp Chat: +91-7001035870 Hyderabad Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Hyderabad understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more. 29-Apr(Ast)

♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...

astropune

Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Available Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Bhubaneswar Escorts Call girls are ready and waiting to provide the quality essentialness that will help ease away life's tensions Bhubaneswar Escorts are regular companions of elite gentlemen and can take them places they could only dream of visiting. These ladies take great care in maintaining themselves to look appealing; visiting salons and spas regularly keeps them looking their best; their portfolios can be found online via an escort’s agency website. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Bhubaneswar Escort Service are adept at performing wild anal sex, deep throat sex and cum eating - perfect for satisfying all your sexual needs and playing any game imaginable. Affordable professional assistants are readily available and ready to assist with any situation - be it romantic date or solo night. Their beautiful appearances and striking personalities will leave you speechless, while they can accompany you to restaurants or bars where their presence will surely leave an impression.

Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...

Dipal Arora

Recently uploaded (20)