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Ágnes Harmath M.D. Ph.D.
senior lecturer
NEONATOLOGY
Healthy newborn. Neonatal sequelaes
11. December 2015.
2
Tasks of the neonatologist
Prenatal diagnosed condition
Inform parents, preparation of necessary intervention
Labor Ward
Handling healthy
newborns
Neonatal sequalae treatment
2
3
Newborn terminology
CLIV. Act of Care 1997 Chapter XII. section 216. d.
„Perinatal Death:
a) Mortality occurs intra uterus post the 24th gestational week or after the
fetus reached 30 cm length or 500 g weight,
b) If the death occurs 168 hours post delivery, irrespective of the growth
parameters of the newborn
3
Perinatal Mortality
Fetal Death Infant Death
4
Terms of newborns
 Mature newborn: 37. – 41 6/7. gestational week
weight: 3500-4500 gramm
length: 45-55 cm
head circumference 32-37 cm
 Over-carried newborn: post 42 . week
 SGA (small for gestational age) newborn
- weight below the 10th percentile
- weight below the average by 2 SD
 LGA (large for gestational age) newborn:
- weight above the 90th percentile
- weight above the average by 2 SD
 Premature birth : age <37 gestational week,
weight <2500 gramms
VLBW (very low birth weight) newborn - <1000 gramms
4
Neonatologist is required in the
labor ward
 Conditions of the mother
toxaemia, chronic disorders, dependency (drug, alcohol, smoking)
 Fetal Condition
multiples, age of fetus (premature or postmature), IUGR (intrauterin growth retardation),
fetal development condition, diagnosed fetal disorder (e.g.: hydrops-syndroma)
 Labour and birth factors:
distochia, meconium stained fluid,early membrane rupture/noticeable odor, bleeding,
umbilical chord disorder, cesarean section
5
Known anamnesis may result in resuscitation in cases of:
Post the normal pregnancy
 Newborn shows symptoms of
changing respiratory rate, cyanosis, meconium stained fluid, hydrops syndrome
Apgar test tube can’t get through, development disorders
 Healthy newborn condition deteriorates
6
Labor ward treatment
 Newborn resuscitation
 Apgar test and score
 Umbilical cord clamp
 Treatment of eyes
 First informative test of newborn
 Development control
- Dubowitz-score – 1977
- New Ballard-score – 1991
 Sterility/Hygienic norms
6
7
Equipment needed for resuscitation
 Open incubator (radiant warmer), phonendoscop,
„Apgar clock”
 Oxygen and breathing space with tube outlets
 Suction and catheters
(both throat and tube suction)
 Equipments for ventilation
(Neopuff, balloon, masks, laryngoscope, tubes)
 Equipments for vein punctions
 Drugs
 Scissors, tape
Resuscitation 2015; 95: 249-263
8
9
10
APGAR score
0 1 2
Pulse absent <100/min >100/min
Respiratory effort absent Irregular Intensive cry
Grimace
(reflex irritability)
Non-responsive Grimace Sneeze or cough
Activity
(Muscle tone)
Absent , limp
Some flexion of
extremities
Strong movement
Appearence
(skin colour)
Pale, blue Acrocyanosis Rosy
Assessment:
8-10 – good outcome
6-7 – endangered condition, NICU observation required
4-5 – average condition, NICU observation required
< 3 – serious asphyxia, life threatening condition
Injuries during delivery
 Prevalence – 1-2%
 Predetermining factors:
macrosomia, premature birth, distochia,
long birth period, breach position
 Cephalhaematoma – most common
 Other injuries: suffusion, skin injury
 Clavicula fracture
 Bone fracture
 Nerve injury: Erb-Duchenne (C5-6), Klumpke (C7-8, Th1)
11
12
Healthy newborn care on ward
 First day of life
Detailed physical examination
Vitamin. K prophylaxis
HBsAg test result – if necessary
injection
 Observation time
sucking and feeding
jaundice
care of the umbilical region
 Day of discharge
Metabolic disease screening test
Hearing test screening
BCG injection
13
Conditions of early discharge
 Normal single pregnancy
 37- 42. gestational week
 Spontaneous vaginal delivery
 Normal prae-,intra- and postpartum period
 12 hours prior to discharge normal and stable
parameters
 At least two successful feeds
 No condition that would justify hospitalization
 Metabolic test results
 Suitable home conditions (home assessment)
 Mother is capable of caring for the newborn
 Within 48 hours if pediatrician (GP) undertakes
the general practice at home
14
Problems at healthy newborns
Managed on normal neonatal ward:
 Tremor
- Hypoglycemia – blood sugar below 1,8-2 mmol/l
- Hypocalcemia – SeCa level below1,7 mmol/l
 Passage disturbances:
-regurgisting, vomiting
- Stool (meconium) problems if it within 24-36 hours recover
 Omphalitis without feeding problems and deterioration of
general condition
 Icterus – physiologic
enough fluid intake supply, blue-light therapy and observation
15
Cases of Intensive Care
requirement
 Post intubation or resuscitation
 Cardiorespiratory disorders
 Prior to 34. gestational week or below 2000 grams of
birthweight
 Symptoms of anemia or shock
 Central nervous system disorders
 Serious development disorders
 Feeding difficulties or reoccurring vomiting
 Infection
 Serious disturbances of ion homeostasis
 Clinical icterus
16
Tasks prior to transfer
 Stabilization, checking clinical signs and vital
parameters till the ambulance arrive
 Inform the staff of ambulance service and the host
hospital before transportation
 Parents information
 Preparing documentation
17
Necessary data:
 Data of perinatal period: mode of delivery, time of membrane
rupture, amniotic fluid condition, medicine usage during
delivery, analgesia
 Data of newborn: birthweight, Apgar points, invasive
treatments, medicaments, infusions, ventilation support,
laboratory findings
 Maternal anamnesis: birthdate, insurance number, blood
group, date of previous pregnancies, acute and chronic
diseases, family anamnesis, regular use of medicine/alcohol/
drug
 Data of recent pregnancy: results of laboratory and
ultrasound and screening tests (e.g..: HBsAg !!)
18
Intensive Care Placement
I. Infection suspicion
II. Development disorders
III. Respiratory condition
IV. Gastrointestinal condition
V. Icterus
VI. Haematologic disorders
VII. Others
- seizures - ion homeostasis disturbances
- injury through delivery - social problems
THANK YOU FOR YOUR KIND
ATTENTION

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Agnes Harmath - Neonatology

  • 1. Ágnes Harmath M.D. Ph.D. senior lecturer NEONATOLOGY Healthy newborn. Neonatal sequelaes 11. December 2015.
  • 2. 2 Tasks of the neonatologist Prenatal diagnosed condition Inform parents, preparation of necessary intervention Labor Ward Handling healthy newborns Neonatal sequalae treatment 2
  • 3. 3 Newborn terminology CLIV. Act of Care 1997 Chapter XII. section 216. d. „Perinatal Death: a) Mortality occurs intra uterus post the 24th gestational week or after the fetus reached 30 cm length or 500 g weight, b) If the death occurs 168 hours post delivery, irrespective of the growth parameters of the newborn 3 Perinatal Mortality Fetal Death Infant Death
  • 4. 4 Terms of newborns  Mature newborn: 37. – 41 6/7. gestational week weight: 3500-4500 gramm length: 45-55 cm head circumference 32-37 cm  Over-carried newborn: post 42 . week  SGA (small for gestational age) newborn - weight below the 10th percentile - weight below the average by 2 SD  LGA (large for gestational age) newborn: - weight above the 90th percentile - weight above the average by 2 SD  Premature birth : age <37 gestational week, weight <2500 gramms VLBW (very low birth weight) newborn - <1000 gramms 4
  • 5. Neonatologist is required in the labor ward  Conditions of the mother toxaemia, chronic disorders, dependency (drug, alcohol, smoking)  Fetal Condition multiples, age of fetus (premature or postmature), IUGR (intrauterin growth retardation), fetal development condition, diagnosed fetal disorder (e.g.: hydrops-syndroma)  Labour and birth factors: distochia, meconium stained fluid,early membrane rupture/noticeable odor, bleeding, umbilical chord disorder, cesarean section 5 Known anamnesis may result in resuscitation in cases of: Post the normal pregnancy  Newborn shows symptoms of changing respiratory rate, cyanosis, meconium stained fluid, hydrops syndrome Apgar test tube can’t get through, development disorders  Healthy newborn condition deteriorates
  • 6. 6 Labor ward treatment  Newborn resuscitation  Apgar test and score  Umbilical cord clamp  Treatment of eyes  First informative test of newborn  Development control - Dubowitz-score – 1977 - New Ballard-score – 1991  Sterility/Hygienic norms 6
  • 7. 7 Equipment needed for resuscitation  Open incubator (radiant warmer), phonendoscop, „Apgar clock”  Oxygen and breathing space with tube outlets  Suction and catheters (both throat and tube suction)  Equipments for ventilation (Neopuff, balloon, masks, laryngoscope, tubes)  Equipments for vein punctions  Drugs  Scissors, tape
  • 9. 9
  • 10. 10 APGAR score 0 1 2 Pulse absent <100/min >100/min Respiratory effort absent Irregular Intensive cry Grimace (reflex irritability) Non-responsive Grimace Sneeze or cough Activity (Muscle tone) Absent , limp Some flexion of extremities Strong movement Appearence (skin colour) Pale, blue Acrocyanosis Rosy Assessment: 8-10 – good outcome 6-7 – endangered condition, NICU observation required 4-5 – average condition, NICU observation required < 3 – serious asphyxia, life threatening condition
  • 11. Injuries during delivery  Prevalence – 1-2%  Predetermining factors: macrosomia, premature birth, distochia, long birth period, breach position  Cephalhaematoma – most common  Other injuries: suffusion, skin injury  Clavicula fracture  Bone fracture  Nerve injury: Erb-Duchenne (C5-6), Klumpke (C7-8, Th1) 11
  • 12. 12 Healthy newborn care on ward  First day of life Detailed physical examination Vitamin. K prophylaxis HBsAg test result – if necessary injection  Observation time sucking and feeding jaundice care of the umbilical region  Day of discharge Metabolic disease screening test Hearing test screening BCG injection
  • 13. 13 Conditions of early discharge  Normal single pregnancy  37- 42. gestational week  Spontaneous vaginal delivery  Normal prae-,intra- and postpartum period  12 hours prior to discharge normal and stable parameters  At least two successful feeds  No condition that would justify hospitalization  Metabolic test results  Suitable home conditions (home assessment)  Mother is capable of caring for the newborn  Within 48 hours if pediatrician (GP) undertakes the general practice at home
  • 14. 14 Problems at healthy newborns Managed on normal neonatal ward:  Tremor - Hypoglycemia – blood sugar below 1,8-2 mmol/l - Hypocalcemia – SeCa level below1,7 mmol/l  Passage disturbances: -regurgisting, vomiting - Stool (meconium) problems if it within 24-36 hours recover  Omphalitis without feeding problems and deterioration of general condition  Icterus – physiologic enough fluid intake supply, blue-light therapy and observation
  • 15. 15 Cases of Intensive Care requirement  Post intubation or resuscitation  Cardiorespiratory disorders  Prior to 34. gestational week or below 2000 grams of birthweight  Symptoms of anemia or shock  Central nervous system disorders  Serious development disorders  Feeding difficulties or reoccurring vomiting  Infection  Serious disturbances of ion homeostasis  Clinical icterus
  • 16. 16 Tasks prior to transfer  Stabilization, checking clinical signs and vital parameters till the ambulance arrive  Inform the staff of ambulance service and the host hospital before transportation  Parents information  Preparing documentation
  • 17. 17 Necessary data:  Data of perinatal period: mode of delivery, time of membrane rupture, amniotic fluid condition, medicine usage during delivery, analgesia  Data of newborn: birthweight, Apgar points, invasive treatments, medicaments, infusions, ventilation support, laboratory findings  Maternal anamnesis: birthdate, insurance number, blood group, date of previous pregnancies, acute and chronic diseases, family anamnesis, regular use of medicine/alcohol/ drug  Data of recent pregnancy: results of laboratory and ultrasound and screening tests (e.g..: HBsAg !!)
  • 18. 18 Intensive Care Placement I. Infection suspicion II. Development disorders III. Respiratory condition IV. Gastrointestinal condition V. Icterus VI. Haematologic disorders VII. Others - seizures - ion homeostasis disturbances - injury through delivery - social problems
  • 19. THANK YOU FOR YOUR KIND ATTENTION