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Ovarian Torsion in Postmenopausal
Women and risk of malignancy
Presented by
Karen Joseph
Group 817
Ovarian torsion (OT) is fifth most
common emergent surgery in gynecology
Ovarian torsion 3% of gynecologic emergencies
Risk Factors:
Anatomic changes affecting the
weight and the size of the ovary
Congenitally malformed
increased length of the ovarian ligaments
Pathologically enlarged ovaries (more than 6 cm)
Enlarged corpus luteum early in pregnancy (20%)
Induction of ovulation and numerous theca lutein cysts
( expand ovarian volume)
Etiology of OT is not clear but in cases of
Ovarian tumors ( 50-60%)
Fewer than half of (OT) is
teratoma and are in pediatric
history of pelvic adhesions
History of pelvic surgery (principally tubal ligation)
Adhesions around ovarian pedicle may twist
Involved masses are nearly all larger than 4-6 cm
although torsion is still possible with smaller masses
Ovarian torsion may rarely occur in normal adnex
 Ovarian torsion has a bimodal age
distribution occurring mainly in
Mid 20s (15-30 years)
( changes in weight of maturing adnexa)
Postmenopausal
The risk is greater during pregnancy
Presentation
Clinical features of adnexal torsion can mimic other
causes of an acute abdomen
Sudden sharp and lower abdominal pain
Nausea and vomiting
In case of necrosis, fever occurs
Unilateral torsion happens (80%)
Slight predominance on the right
History previous episodes (partial)
Spontaneously resolving torsion
Differential Diagnoses:
Ectopic Pregnancy
Ovarian Cysts
Endometriosis
Pelvic Inflammatory Disease
Nephrolithiasis
Urinary Tract Infection
Appendicitis
Diverticulitis
Large Bowel Obstruction
Mesenteric Ischemia
Small Bowel obstruction
Perforated colonic carcinoma
Ovarian tumors
both benign and malignant, are implicated
in 50-60% of cases of torsion
Malignancy may be associated with ovarian torsion in
1.1% -2% of adult patients
malignancy incidence was 25% in
women older than 60 years
Malignant tumors are much less likely to
result in torsion than benign tumors
This is because of the presence of
cancerous adhesions that fix the ovary to
surrounding tissues
The risk of ovarian torsion is increased in post-
menopausal women who had ovarian mass
both benign and malignant
we must be considered the possibility of
underlying ovarian cancer in postmenopausal
patients with Ovarian torsion
Lee et al., in review of 135 cases of adnexal
torsion, incidence of malignancy was reported
15%
the incidence was 25% in women older than 60
years
Dermoid tumors
are most common in ovarian tumor
Diagnosis of OT is difficult, it seems that
contribution of clinical history
clinical examination
laboratory investigations are important
Ultrasound is the diagnostic modality of
choice for detecting OT
Once OT occurred initially venous flow is compromised
which results in congestion of the ovary
then lymphatic engorgement
edema and haemorrhage
and finally infarction occurred
after persistent black color of the adnex
(6-8 hours )
functional recovery is impossible
early diagnosis can be critical
Doppler analysis is the method of choice
(Venous flow is under low pressure)
first flow to be affected
Increased interstitial pressure of a twisted ovary
In chronic torsion
arterial waveforms can mimic
venous waveforms
Complete torsion no arterial waveforms
normal Doppler blood flow,
cannot exclude the diagnosis of OT
CT-scan in ovarian torsion is
nonspecific, but it may be helpful in
ruling out these conditions
Ultrasound alone is inadequate while
Doppler investigation often misses
the diagnosis
The result is an increased number of
unnecessary laparoscopies in certain
The definite diagnosis of adnexal
torsion is
surgery
laparoscopy or laparotomy
can be diagnostic and therapeutic
treatment of OT should be made imperative
We must be considered loss of the ovary
base on delayed in surgery
Almost all of literature agree that if
the ovary is detoured within
8 hours is with best outcomes
So emergency surgery is recommended
Drainage of cyst or cystectomy significantly
reduce the chance of re-torsion by
50% and 75% respectively
compared to detorsion
as possible as the ovary must be untwisted
and allowed to restore ovarian function
Delayed diagnosis may lead to tissue
necrosis, incorrect pathologic diagnosis,
rapture of ovarian necrotic material and
making patient in hazard
Balci and et al. in a retrospective analysis reported
5-year experience of surgical results
comparing between laparoscopy and laparotomy
in patients with adnexal torsion
and noted that laparoscopy is preferred for young
patients who want to preserve their fertility
Tsafrir in 2012 reported his clinical
experience in 216 cases of adnexal
torsion and recommended that
cystectomy should be considered in
order to reduce the risk of re-torsion
The main hesitation concerning of
conservative treatment consists of the
theoretical fear of
thromboembolic complications secondary to
untwisting of ischaemic adnexa
However, the incidence of pulmonary
embolism in case of adnexal torsion is 0.2%
This incidence is no greater after untwisting
No increase in the number of thromboembolic
complications after untwisting is evident from
the literature
One of the main hesitation concerning in treatment
consists loss of frozen section analysis
Frozen section during surgery must be
considered for all of these patients
must be noted that extensive necrotic tissue in
adnexal mass may be under-diagnosis
of malignancy on frozen section
if utilized in suspected malignancy cases,
staging surgery should be performed
because presumably emergency surgery
in majority of cases frozen section often
unavailable
when malignancy is suspected, surgeons
should be rely more on clinical evaluation
therefore, perform surgical staging
surgery
Recurrence rate of 19.5%
in pregnant women
9.1% in
non pregnant women
no cases of death due to ovarian
torsion have been reported
The advantage of early diagnosis of adnexal
torsion is prevention of complications
Conclusion
Adnexal torsion should be considered as an
emergency
malignancy may be responsible for ovarian
torsion in post-menopausal women
tortion.pptx

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tortion.pptx

  • 1.
  • 2. Ovarian Torsion in Postmenopausal Women and risk of malignancy Presented by Karen Joseph Group 817
  • 3. Ovarian torsion (OT) is fifth most common emergent surgery in gynecology Ovarian torsion 3% of gynecologic emergencies
  • 4. Risk Factors: Anatomic changes affecting the weight and the size of the ovary Congenitally malformed increased length of the ovarian ligaments Pathologically enlarged ovaries (more than 6 cm) Enlarged corpus luteum early in pregnancy (20%) Induction of ovulation and numerous theca lutein cysts ( expand ovarian volume)
  • 5. Etiology of OT is not clear but in cases of Ovarian tumors ( 50-60%) Fewer than half of (OT) is teratoma and are in pediatric history of pelvic adhesions History of pelvic surgery (principally tubal ligation) Adhesions around ovarian pedicle may twist
  • 6. Involved masses are nearly all larger than 4-6 cm although torsion is still possible with smaller masses Ovarian torsion may rarely occur in normal adnex
  • 7.  Ovarian torsion has a bimodal age distribution occurring mainly in Mid 20s (15-30 years) ( changes in weight of maturing adnexa) Postmenopausal The risk is greater during pregnancy
  • 8. Presentation Clinical features of adnexal torsion can mimic other causes of an acute abdomen Sudden sharp and lower abdominal pain Nausea and vomiting In case of necrosis, fever occurs Unilateral torsion happens (80%) Slight predominance on the right History previous episodes (partial) Spontaneously resolving torsion
  • 9. Differential Diagnoses: Ectopic Pregnancy Ovarian Cysts Endometriosis Pelvic Inflammatory Disease Nephrolithiasis Urinary Tract Infection
  • 10. Appendicitis Diverticulitis Large Bowel Obstruction Mesenteric Ischemia Small Bowel obstruction Perforated colonic carcinoma
  • 11. Ovarian tumors both benign and malignant, are implicated in 50-60% of cases of torsion Malignancy may be associated with ovarian torsion in 1.1% -2% of adult patients malignancy incidence was 25% in women older than 60 years
  • 12. Malignant tumors are much less likely to result in torsion than benign tumors This is because of the presence of cancerous adhesions that fix the ovary to surrounding tissues
  • 13. The risk of ovarian torsion is increased in post- menopausal women who had ovarian mass both benign and malignant we must be considered the possibility of underlying ovarian cancer in postmenopausal patients with Ovarian torsion
  • 14. Lee et al., in review of 135 cases of adnexal torsion, incidence of malignancy was reported 15% the incidence was 25% in women older than 60 years
  • 15. Dermoid tumors are most common in ovarian tumor
  • 16. Diagnosis of OT is difficult, it seems that contribution of clinical history clinical examination laboratory investigations are important Ultrasound is the diagnostic modality of choice for detecting OT
  • 17. Once OT occurred initially venous flow is compromised which results in congestion of the ovary then lymphatic engorgement edema and haemorrhage and finally infarction occurred after persistent black color of the adnex (6-8 hours ) functional recovery is impossible early diagnosis can be critical
  • 18. Doppler analysis is the method of choice (Venous flow is under low pressure) first flow to be affected Increased interstitial pressure of a twisted ovary
  • 19. In chronic torsion arterial waveforms can mimic venous waveforms Complete torsion no arterial waveforms
  • 20. normal Doppler blood flow, cannot exclude the diagnosis of OT CT-scan in ovarian torsion is nonspecific, but it may be helpful in ruling out these conditions
  • 21. Ultrasound alone is inadequate while Doppler investigation often misses the diagnosis The result is an increased number of unnecessary laparoscopies in certain
  • 22. The definite diagnosis of adnexal torsion is surgery laparoscopy or laparotomy can be diagnostic and therapeutic
  • 23. treatment of OT should be made imperative We must be considered loss of the ovary base on delayed in surgery Almost all of literature agree that if the ovary is detoured within 8 hours is with best outcomes So emergency surgery is recommended
  • 24. Drainage of cyst or cystectomy significantly reduce the chance of re-torsion by 50% and 75% respectively compared to detorsion
  • 25. as possible as the ovary must be untwisted and allowed to restore ovarian function Delayed diagnosis may lead to tissue necrosis, incorrect pathologic diagnosis, rapture of ovarian necrotic material and making patient in hazard
  • 26. Balci and et al. in a retrospective analysis reported 5-year experience of surgical results comparing between laparoscopy and laparotomy in patients with adnexal torsion and noted that laparoscopy is preferred for young patients who want to preserve their fertility
  • 27. Tsafrir in 2012 reported his clinical experience in 216 cases of adnexal torsion and recommended that cystectomy should be considered in order to reduce the risk of re-torsion
  • 28. The main hesitation concerning of conservative treatment consists of the theoretical fear of thromboembolic complications secondary to untwisting of ischaemic adnexa However, the incidence of pulmonary embolism in case of adnexal torsion is 0.2%
  • 29. This incidence is no greater after untwisting No increase in the number of thromboembolic complications after untwisting is evident from the literature
  • 30. One of the main hesitation concerning in treatment consists loss of frozen section analysis Frozen section during surgery must be considered for all of these patients must be noted that extensive necrotic tissue in adnexal mass may be under-diagnosis of malignancy on frozen section
  • 31. if utilized in suspected malignancy cases, staging surgery should be performed because presumably emergency surgery in majority of cases frozen section often unavailable when malignancy is suspected, surgeons should be rely more on clinical evaluation therefore, perform surgical staging surgery
  • 32. Recurrence rate of 19.5% in pregnant women 9.1% in non pregnant women
  • 33. no cases of death due to ovarian torsion have been reported
  • 34. The advantage of early diagnosis of adnexal torsion is prevention of complications
  • 35. Conclusion Adnexal torsion should be considered as an emergency malignancy may be responsible for ovarian torsion in post-menopausal women