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Curriculum Vitae	
  	
  
Jose	
  F.	
  Caro,	
  M.D.	
  
Artist
Dis/nguished	
  Professor	
  of	
  Medicine	
  Emeritus	
  
General	
  Informa/on	
  
Home	
  Address:	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  5947	
  McKinges	
  Circle	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Carmel,	
  IN	
  4603	
  
Telephone:	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  252-­‐414-­‐1738	
  
Email:	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  jfcaro13@gmail.com	
  
webs:	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.josefcaro.com	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.linkedin.com/in/josefcaro	
  
Birthplace:	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Granada,	
  Spain;	
  June	
  27,	
  1948	
  
CiUzenship:	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  USA	
  
Marital	
  Status:	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Married	
  with	
  Marice	
  E.	
  Caro	
  for	
  42	
  years	
  
Children:	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Maricelina,	
  Rodolfo,	
  Marina	
  and	
  Rafael	
  
Grand	
  Children:	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Olivia,	
  Elise,	
  Bridget,	
  Julia	
  and	
  Julian	
  
Summary	
  
Jose F. Caro began a new career in art in 2008. He went back to college to pursue a degree in fine art
and is having his pastel paintings peer reviewed by his colleagues. Before this transformation he was the
Vice President of Endocrine Research and Clinical Investigation and Global Diabetes Care at Eli Lilly &
Comp for 12 years. Prior to joining Lilly he was the Magee Professor of Medicine and Chairman of the
Department at Jefferson Medical College for 5 years and the Chief of Endocrinology and Director of the
University Diabetes Center at East Carolina University for 10 years.
Dr. Caro received his M.D. degree with honors in 1973 from the School of Medicine in Madrid, Spain and
Montevideo, Uruguay. He completed residency and fellowship training at Jefferson Medical College and
at the University of Rochester. He is Board Certified in Internal Medicine and Endocrinology and
Metabolism.
Dr. Caro was a member of various professional and honorary societies, including the American Society
for Clinical Investigation (Young Turk) and the Association of American Physicians (Old Turk). He was the
recipient of the Medal of Honor and is an honorary member of the Real Academy of Medicine of Granada,
Spain. He is the Honorary Director of the Peking Diabetes Center and Honorary Professor of the Peking
University Health Science Center in China.Dr.
He has authored about 200 papers, book chapters and books and he was recently listed as the third most
highly cited investigator in the world in the field of Obesity Research by ISI. He served as Editor and
Editorial Board member of several journals and has lectured around the world. Dr. Caro has served as a
member and Chairman of several study sections at the NIH and more recently as a member of the NIDDK
Advisory Council to the President.
He lives in Carmel IN with Marice, his spouse for 42 years. His main artistic inspiration is his family...his
four children and five grandchildren.
________________________ART_______________________________	
  
Why	
  a	
  Second	
  Career	
  in	
  Art?	
  
My great granduncle, Rafael Eiroa, was an artist in the late XIX century Spain. One of his paintings was in
my parents’ home. It was a middle age woman sitting in a dilapidated straw chair. Her eyes were unfixed
and gazed into space. It was almost as if she was waiting to catch the opportunity she did not have. 
Every night I fell to sleep thinking about her, about opportunities, the future, and most definitively that I
wanted to paint like my uncle Rafael. 
After the Spanish Civil war, my family like many others immigrated to Argentina looking for the freedom
they did not have. I still remember vividly those 21 days crossing the ocean aboard the steamship Buena
Esperanza (Good Hope).  My great granduncle’s large canvas was carefully removed from the frame by
my father, rolled and stored into a trunk labeled “memories from Spain”.
Many years had passed before my mother decided to open the trunk.  The canvas was severely
damaged.  I was a teenager and had forgotten the woman sitting in a chair. Nevertheless, my parents
knowing my interest for art suggested that I repair her. I bought oils and brushes and I did it! I knew then
what I wanted to become. But when I told my father about my desire to enter the school of art he said
“study son, you will always have time to paint”. 
I became a physician and soon after graduation I moved to the USA with my wife and daughter looking for
freedom and opportunities, like my parents did. It has been a great 40 years journey but I never found
time to paint like my father said. Thus, I left medicine and science at age 60 to find time to paint. My
youngest son Rafael after reading this statement he smiled and firmly said “I will start a career in art this
fall semester”. If I finish wanting to paint like my uncle Rafael and my son Rafael, I would say it is not a
bad way to end.
Presentations at Juried Shows.-
2009 Greenville Museum of Art Annual Juried Show. Greenville, NC
“Only in California” and “The Magic Five Minutes in the Morning”
2011 Pastel Society of North Carolina, Winter Exhibition. Greensboro, NC
“The Beach at Acadia National Park”
2013 Ninth Annual Northeast National Pastel Exhibition, Old Forge, NY
“I am not a little girl anymore”
2013 27th Annual International Exhibit. Northwest Pastel Society. Tacoma,
WA
“At Acadia National Park”
2013 First Carteret County Juried Art Show. Emerald Isle, NC
“Shall I grow up?” and “At the Poconos Mountains”
2013 North Carolina Statewide Juried Pastel Exhibition. On Common
Grounds: Pastel Paintings From The Mountains To The Sea.
“I am not a little girl anymore”
2013 The 23rd International Association of Pastel Societies Juried
Exhibition. Marshfield, MA
“I am not a little girl anymore”
2014 The Southeastern Pastel Society’s 16th International Exhibition.
Oglethorpe University Museum of Art. Atlanta, GA
“I am Not Alone” and “Dreaming About Spring”
2014 28th Annual International Exhibit. Northwest Pastel Society.
Tacoma, WA
“At Acadia National Park”
2014 Northeast National Pastel Exhibition, View.Old Forge NY
“Maternity”
2014 Degas Pastel Society Fifteenth Biennial National Exhibition. New
Orleans, LA.
“Maternity” and “I am not alone”
2014 Southeastern Pastel Society On-Line Juried Exhibition.
“Choices”
2015 Pastel Society of the West Coast 2015 Annual Members Show.
Haggis Museum, Stockton, CA.
“I am not alone”
2015 Southeastern 2015 juried members exhibition. Quinlan Visual Art

Center, Gainesville, GA.
“Maternity”
2015 Degas Pastel Society Nineteenth Membership Exhibition. New
Orleans, LA
“Choices” and “I am not a little girl anymore”
2015 The Peninsula Art League 2015 Open Juried Show. Harbor
History Museum, Gig Harbor, WA
“Maternity” and “The hug”
One Person Shows.-
2013 Emerald Isle Recreation Center, Emerald Isle, NC
2013 Bogue Banks Public Library, Pine Knoll Shores, NC
2013 Arts for the Hospital, Carteret Hospital, Morehead City, NC
Presentations at Non Juried Shows.-
2013 Art for the Heart Annual Exhibition. Carteret County Art Council.
Morehead City, NC .
“I am not a little girl any more” and “The beach at Emerald Isle”
Awards/Honors/Publications.-
2012 The Editor Choice: “Celebration of Water”. Art & Beyond Vol. 6,
page 16, 2012.
2013 Juried Associate Member of the Pastel Society of America (PSA)
2013 Featured Artist of the Week with “Are we ready to leave home” at
Artists Registry.com
2013 Featured Artwork @The Library. The Shoreline, Vol. 9, No. 8, p. 10
2013 Featured Pastel Artist. News-Time, Vol. 102, No.59, p.
2013 News and Mentions. Art Line, Pastel Society of NC. Vol. 2013 May
2014 The Artist’s Magazine. Annual Art Competition. Portrait/Figure
Third Place Winer “I am not a little girl anymore”
2015 Juried Full Member of the Degas Pastel Society.
2015 Juried Full Member Indiana Artists Club
Professional Societies and Memberships.-
2008 - 2012 The Indiana Art Association
2009 - Present Hoosier Salon, Patron Association and Fine Art Gallery
2009 - 2012 Northern Indiana Pastel Society
2012 - 2014 Craven Arts Council & Gallery, Inc., NC
2012 - 2014 Seaside Arts Council, NC
2012 - 2014 Art Council of Carteret County, NC
2012- 2014 Pastel Society of North Carolina
2012- 2014 Greenville Museum of Art, NC
2013- Present Juried Associate Member Pastel Society of America (PSA)
2013- Present Northwest Pastel Society
2014- Present Southeastern Pastel Society
2014 - Present Juried member of the Degas Pastel Society
Invited Lectures. -
“The role of art in society”. Lookout Rotary Club, Morehead City, NC 2012
“The Past and Present of Pastel Painting”. At the Art for the Hospital Annual Meeting.
Carteret Community Hospital, Morehead City, NC 2013
Consultant/Advisory Activities. -
Member of the Board of Arts for the Hospital. Carteret County Community Hospital,
Morehead City, NC
Member of the Jury for Arts for the Heart, Student Category, Carteret County Art
Council, Morehead City, NC
Art education.-
2008-2010 Semester Courses in Fine Art at the Indianapolis Art Center.
2010-2012 Study Fine Art at CCC College, Morehead City, NC
2011-Present Participation at Workshops, critic sections and art classes with
experience artists such us W. Creevy, R. McKinley, P. Newell.
_______________________MEDICINE_____________________	
  
MEDICAL	
  EDUCATION	
  
1967	
  -­‐	
  1973	
   	
   School	
  of	
  Medicine,	
  Universidad	
  Autonoma	
  de	
  Madrid,	
  Spain	
  and	
  School	
  of	
  Medicine,	
  
Universidad	
  de	
  la	
  Republica,	
  Montevideo,	
  Uruguay	
  	
  
POSTGRADUATE	
  TRAINING	
  
1974	
  -­‐	
  1977	
   	
   Residency	
   in	
   Internal	
   Medicine,	
   Thomas	
   Jefferson	
   University	
   Hospital	
   of	
   Thomas	
  
Jefferson	
  University,	
  Philadelphia,	
  Pennsylvania	
  
1977	
  -­‐	
  1978	
   	
   Fellowship	
   in	
   Internal	
   Medicine,	
   Thomas	
   Jefferson	
   University	
   Hospital	
   of	
   Thomas	
  
Jefferson	
  University,	
  Philadelphia,	
  Pennsylvania	
  
1978	
  -­‐	
  1981	
   	
   Fellowship	
   in	
   Endocrinology	
   and	
   Metabolism,	
   Strong	
   Memorial	
   Hospital,	
   University	
   of	
  
Rochester	
  School	
  of	
  Medicine	
  and	
  DenUstry,	
  Rochester,	
  New	
  York	
  
CERTIFICATIONS	
  
1979	
   	
   	
   Board	
  CerUficaUon	
  in	
  Internal	
  Medicine,	
  American	
  Board	
  of	
  Internal	
  Medicine	
  
1984	
   	
   	
   Board	
   CerUficaUon	
   in	
   Endocrinology	
   and	
   Metabolism,	
   American	
   Board	
   of	
   Internal	
  
Medicine	
  
APPOINTMENTS	
  
1981	
  -­‐	
  1983	
   	
   Assistant	
   Professor	
   of	
   Medicine,	
   Endocrinology	
   and	
   Metabolism,	
   Jefferson	
   Medical	
  
College	
  of	
  Thomas	
  Jefferson	
  University,	
  Philadelphia,	
  Pennsylvania	
  
1983	
  -­‐	
  1986	
   	
   Associate	
  Professor	
  of	
  Medicine,	
  SecUon	
  Head	
  of	
  Endocrinology	
  and	
  Metabolism,	
  East	
  
Carolina	
  University	
  School	
  of	
  Medicine,	
  Greenville,	
  North	
  Carolina	
  
1986	
  -­‐	
  1991	
   	
   Professor	
  of	
  Medicine,	
  SecUon	
  Head	
  of	
  Endocrinology	
  and	
  Metabolism	
  and	
  Director	
  of	
  
the	
  University	
  Diabetes	
  Center,	
  East	
  Carolina	
  University	
  School	
  of	
  Medicine,	
  Greenville,	
  
North	
  Carolina	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  The	
  Division	
  of	
  Endocrinology	
  and	
  Metabolism	
  was	
  founded.	
  Six	
  faculUes	
  were	
  recruited	
  
and	
  mentored	
  and	
  all	
  became	
  funded	
  by	
  the	
  NIH.	
  A	
  comprehensive	
  Fellowship	
  Program	
  
was	
   approved.	
   The	
   ECU	
   Diabetes	
   and	
   Obesity	
   Center	
   was	
   established.	
   Dr.	
   J.	
   F.	
   Caro	
  
became	
  Program	
  Director	
  of	
  the	
  “ECU	
  Diabetes	
  Program	
  Project”,	
  the	
  largest	
  NIH	
  award	
  
in	
   the	
   history	
   of	
   the	
   University.	
   Basic	
   research	
   discoveries	
   were	
   made	
   such	
   as	
  
mechanism(s)	
  of	
  IRTK	
  defects	
  in	
  liver,	
  muscle	
  and	
  liver	
  from	
  humans	
  with	
  diabetes	
  and	
  
clinical	
  research	
  observaUons	
  were	
  made	
  such	
  as	
  that	
  the	
  gastric	
  bypass	
  surgery	
  prevent	
  
diabetes	
  by	
  40	
  folds	
  in	
  people	
  with	
  pre-­‐diabetes	
  and	
  reverse	
  diabetes	
  in	
  more	
  than	
  80	
  
percent	
  of	
  paUents	
  for	
  more	
  than	
  10	
  years.	
  
1991	
  -­‐	
  1996	
   	
   Magee	
   Professor	
   of	
   Medicine	
   and	
   Chairman	
   of	
   the	
   Department,	
   Jefferson	
   Medical	
  
College	
  of	
  Thomas	
  Jefferson	
  University,	
  Philadelphia,	
  Pennsylvania	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  The	
  Department	
  of	
  Medicine	
  tripled	
  its	
  NIH	
  funding	
  and	
  moved	
  from	
  the	
  middle	
  third	
  to	
  
the	
  upper	
  third	
  of	
  NIH	
  ranking.	
  The	
  residency	
  program	
  became	
  the	
  largest	
  in	
  the	
  State	
  
with	
  most	
  house	
  staff	
  elecUng	
  a	
  career	
  on	
  primary	
  care.	
  Out	
  paUent	
  encounters	
  tripled	
  
and	
  hospital’s	
  paUent	
  duraUon	
  of	
  hospitalizaUon	
  decreased	
  by	
  half.	
  The	
  budget	
  of	
  the	
  
Department	
   conUnued	
   generaUng	
   overage	
   for	
   program	
   development.	
   All	
   this	
   was	
  
achieved	
   without	
   a	
   significant	
   increase	
   in	
   FTEs.	
   This	
   is	
   what	
   our	
   Dean	
   called	
  
“producUvity	
  without	
  expansion”	
  
1996	
  -­‐	
  2008	
   	
   Vice	
   President,	
   Endocrine	
   Research	
   and	
   Clinical	
   InvesUgaUon	
   and	
   Vice	
   President	
   of	
  
Global	
  Diabetes	
  Care.	
  Lilly	
  Research	
  Laboratories,	
  Eli	
  Lilly	
  &	
  Comp,	
  Lilly	
  Corporate	
  Center,	
  
Indianapolis,	
  IN	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  The	
  focus	
  was	
  on	
  drug	
  discovery	
  from	
  hypothesis	
  generaUon	
  in	
  the	
  laboratory	
  to	
  prove	
  
of	
  concept	
  in	
  phase	
  2	
  clinical	
  trials.	
  The	
  effort	
  involved	
  a	
  heavily	
  matrix	
  organizaUon	
  with	
  
chemistry,	
   toxicology,	
   ADME,	
   biology,	
   clinical	
   pharmacology,	
   markeUng,	
   business,	
   etc.	
  
More	
  than	
  40	
  compounds	
  were	
  discovered	
  that	
  fulfilled	
  all	
  FDA	
  requirements	
  to	
  enter	
  
clinical	
  trials.	
  The	
  endocrine	
  porlolio	
  transformed	
  from	
  only	
  Insulin	
  to	
  a	
  more	
  complete	
  
porlolio	
   with	
   several	
   INDs	
   and	
   NDAs	
   sUll	
   in	
   clinical	
   trials	
   from	
   this	
   decade’s	
   drug	
  
discovery	
  pipeline.	
  
1996	
  -­‐	
  2008	
   	
   Professor	
  of	
  Medicine,	
  Indiana	
  University	
  School	
  of	
  Medicine	
  
	
   	
   	
   Indianapolis,	
  IN	
  
2005	
  -­‐	
  Present	
   	
   DisUnguished	
   Professor	
   of	
   Medicine,	
   Emeritus,	
   East	
   Carolina	
   University	
   School	
   of	
  
Medicine,	
  Greenville,	
  NC	
  
2007	
  –	
  Present	
   	
   Co-­‐Founder,	
   Chief	
   ScienUfic	
   Officer	
   Emeritus	
   and	
   Honorary	
   Member	
   of	
   the	
   ExecuUve	
  
Commioee	
  of	
  Peers	
  for	
  Progress.	
  AAFP,	
  University	
  of	
  North	
  Carolina,	
  Chapel	
  Hill,	
  NC	
  
2012-­‐Present	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  President	
  and	
  Founder,	
  JFC	
  SoluUons	
  LLC	
  
AWARDS	
  AND	
  RESEARCH	
  GRANTS	
  (direct	
  cost	
  only)	
  
1979	
  -­‐	
  1981	
   	
   Juvenile	
  Diabetes	
  FoundaUon	
  Fellowship	
  Award	
  (P.I.)	
  
  	
   	
   ($75,000)	
  
1981	
  -­‐	
  1983	
   	
   American	
  Diabetes	
  AssociaUon	
  Wayne	
  Newton	
  Research	
  Grant	
  (P.I.)	
  
	
   	
   	
   ($68,750)	
  
1981	
  -­‐	
  1982	
   	
   Small	
  Grant	
  Award	
  PHS	
  Biomedical	
  Research	
  Support	
  Grant	
  5	
  	
  S07RR0514,	
  Jefferson	
  	
  
	
   	
   	
   	
  Jefferson	
  Medical	
  College	
  (P.I.)	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  ($120,000)	
  
1981	
  -­‐	
  1982	
   	
   Department	
  of	
  Medicine	
  Research	
  Grant,	
  Jefferson	
  Medical	
  	
   College	
  (P.I.)	
  
	
   	
   	
   ($12,500)	
  
1981	
  -­‐	
  1983	
   	
   Juvenile	
  Diabetes	
  FoundaUon	
  Research	
  Grant	
  (P.I.)	
  
	
   	
   	
   ($110,000)	
  
1982	
  -­‐	
  1983	
   	
   Research	
  Grant,	
  Upjohn	
  Company	
  (P.I.)	
  
	
   	
   	
   ($31,250)	
  
1982	
  -­‐	
  1985	
   New	
  InvesUgator	
  Research	
  Award	
  1	
  R23AM	
  30558,	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (PI)	
  
	
   	
   	
   ($176,500)	
  
1984	
  -­‐	
  1985	
   	
   Research	
  Grant,	
  5-­‐81011	
  Years	
  Laboratories	
  (P.I.)	
  
	
   	
   	
   ($43,750)	
  
1985	
  -­‐	
  1987	
   	
   Research	
  Grant,	
  Upjohn	
  Company	
  (P.I.)	
  
	
   	
   	
   ($50,000)	
  
1985	
  -­‐	
  1988	
   	
   Research	
  Grant,	
  R01-­‐AM	
  32585	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (P.I.)	
  
	
   	
   	
   ($297,000)	
  
1986	
  -­‐	
  1990	
   Research	
  Grant,	
  R01-­‐DK	
  38066	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (P.I.)	
  (This	
  grant	
  was	
  funded	
  
but	
  was	
  inacUvated	
  because	
  of	
  overlap	
  with	
  the	
  Program	
  Project	
  DK	
  36296	
  
1987	
  -­‐	
  1988	
   	
   Sponsor	
   of	
   Fogerty	
   Fellowship	
   Award	
   from	
   the	
   NaUonal	
   InsUtutes	
   of	
   Health	
  
(IF05TW04048)	
  to	
  Dr.	
  Ivan	
  Contreras	
  
1987	
  -­‐	
  1992	
   	
   ECU	
   Diabetes	
   Program	
   Project,	
   P01-­‐DK	
   36296	
   NaUonal	
   InsUtutes	
   of	
   Health	
   (Program	
  
Director)	
  
	
   	
   	
   ($2,550,000)	
  
1987	
  -­‐	
  1992	
   	
   Research	
  Grant,	
  Eli	
  Lilly	
  Company	
  (P.I.)	
  
	
   	
   	
   ($375,000)	
  
1988	
  -­‐	
  1989	
   	
   Research	
  Grant,	
  Glaxo	
  PharmaceuUcal	
  Company	
  (P.I.)	
  	
  
	
   	
   	
   ($62,500)	
  
1988	
  -­‐	
  1989	
   	
   Research	
  Grant,	
  R03-­‐DK	
  41191-­‐1	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (P.I.)	
  
	
   	
   	
   ($41,250)	
  
1988	
  -­‐	
  1989	
   	
   Research	
  Grant,	
  Pfizer	
  PharmaceuUcal	
  Company	
  (P.I.)	
  
	
   	
   	
   ($30,000)	
  
1989	
  -­‐	
  1992	
   Sponsor	
  of	
  Fellowship	
  Award	
  from	
  the	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (IF32DK08477)	
  to	
  Dr.	
  
Jacob	
  Friedman	
  
1990	
  -­‐	
  1991	
   	
   Research	
  Grant,	
  Park	
  Davis	
  PharmaceuUcal	
  Company	
  (P.I.)	
  
	
   	
   	
  
1990	
   Small	
  Grant	
  Award:	
  Roaring	
  VisiUng	
  Professorship	
  Program	
  in	
  Diabetes	
  Management	
  
	
   	
   	
   ($6,250)	
  
1990	
   	
   	
   Research	
  Grant,	
  1R03-­‐DK	
  2924	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (P.I.)	
  
	
   	
   	
   ($41,250)	
  
1990	
  -­‐	
  1992	
   	
   Research	
  Grant,	
  Amylin	
  PharmaceuUcal	
  Company	
  (P.I.)	
  ($100,000)	
  
1991	
  -­‐	
  1993	
   	
   Sponsor	
   of	
   Fellowship	
   Award	
   to	
   Dr.	
   Bartolome	
   Burguera	
   from	
   the	
   Juvenile	
   Diabetes	
  
FoundaUon	
  
1991	
  -­‐	
  1992	
   	
   Research	
  Grant,	
  Hoechst-­‐Roussel	
  PharmaceuUcals,	
  Inc.	
  (P.I.)	
  
	
   	
   	
   ($62,500)	
  
1992	
  -­‐	
  1994	
   	
   Sponsor	
  of	
  Fellowship	
  Award	
  to	
  Dr.	
  Robert	
  Considine	
  from	
  the	
  	
   	
   	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (IF32DK08888)	
  
1993	
  -­‐	
  1994	
   	
   Research	
  Grant,	
  Eli	
  Lilly	
  Company	
  (P.I.)	
  
	
   	
   	
   ($96,015)	
  
1993	
  -­‐	
  1994	
   	
   Research	
  Grant,	
  Eli	
  Lilly	
  Company	
  	
  (Co-­‐PI)	
  
	
   	
   	
   ($65,235)	
  
1993	
  -­‐	
  1995	
   	
   Research	
  Grant,	
  Amylin	
  PharmaceuUcal,	
  Inc.	
  (P.I.)	
  
	
   	
   	
   ($37,676)	
  
1994	
  -­‐	
  1995	
   	
   Research	
  Grant,	
  Miles	
  Laboratories	
  (P.I.)	
  
	
   	
   	
   ($153,125)	
  
1994	
  -­‐	
  1995	
   	
   Research	
  Grant,	
  Pfizer	
  PharmaceuUcals	
  (Co-­‐Invest.)	
  
	
   	
   	
   ($37,500)	
  
1994	
  -­‐	
  1996	
   	
   Research	
  Grant,	
  CI-­‐991,	
  Park	
  Davis	
  PharmaceuUcals	
  (Co-­‐Invest.)	
  
	
   	
   	
   ($47,000)	
  
1992	
  -­‐	
  1997	
   	
   Research	
  Grant,	
  R01-­‐DK	
  44950	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (P.I)	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  ($1,900,000)	
  	
  	
  
1994	
  -­‐	
  2002	
   	
   Research	
  Grant,	
  UO1-­‐DK48468,	
  NaUonal	
  InsUtutes	
  of	
  Health	
  (P.I.)	
  	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  ($3,422,165)	
  
SPECIAL	
  RESEARCH	
  GRANTS	
  
2006-­‐2012	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Bringing	
  Research	
  In	
  Diabetes	
  Through	
  Environment	
  and	
  Systems	
  	
  (BRIDGES).	
  See	
  	
  	
  Press	
  
Release	
   Cape	
   Town,	
   South	
   Africa,	
   5	
   December	
   2006	
   BRIDGES@IDF.org	
   Dr.	
   Caro	
  
idenUfied	
  the	
  need	
  of	
  translaUonal	
  research	
  in	
  diabetes	
  at	
  the	
  global	
  level.	
  He	
  wrote	
  a	
  
Grant	
   to	
   the	
   Lilly	
   FoundaUon	
   and	
   provided	
   support	
   to	
   the	
   InternaUonal	
   Diabetes	
  
FederaUon.	
  	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  ($10,000,000)	
  
2007-­‐2012	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Peers	
  for	
  Progress.	
  See	
  Press	
  Release	
  Leak	
  wood,	
  KS,	
  USA,	
  June	
  20,	
  2007,www.lilly.com/
product/acceess/foundaUon,	
  Peersforprogress.org	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Dr.	
  Caro	
  idenUfied	
  the	
  need	
  of	
  new	
  methods	
  for	
  paUent	
  educaUon	
  in	
  diabetes.	
  He	
  wrote	
  
a	
  Grant	
  to	
  the	
  Lilly	
  FoundaUon	
  and	
  provided	
  support	
  to	
  the	
  American	
  Academy	
  of	
  Family	
  
Physicians	
  FoundaUon.	
  Peers	
  for	
  progress	
  will	
  idenUfy	
  and	
  train	
  laid	
  volunteers	
  who	
  have	
  
diabetes	
  and	
  empower	
  them	
  to	
  assist	
  other	
  people	
  with	
  diabetes.	
  The	
  goal	
  is	
  to	
  educate	
  
one	
  percent	
  of	
  the	
  people	
  with	
  diabetes	
  or	
  two	
  million	
  diabetes	
  to	
  become	
  mentors	
  
around	
   the	
   world.	
   The	
   concept	
   was	
   validated	
   at	
   a	
   World	
   Health	
   OrganizaUon	
  
consultaUon,	
  5-­‐7	
  November	
  2007	
  in	
  Geneva.	
  
	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  ($15,000,000)	
  
HONORS	
  AND	
  NAMED	
  LECTURESHIPS	
  
1986-­‐1992	
   	
   Recipient	
   of	
   the	
   “	
   Pearl	
   Lecturer”	
   every	
   year	
   while	
   in	
   the	
   Faculty	
   (Senior	
   Medical	
  
Students'	
  Teaching	
  Award).	
  East	
  Carolina	
  University	
  School	
  of	
  Medicine,	
  Greenville,	
  NC	
  
1988	
  -­‐2012	
   	
   Member	
  of	
  the	
  American	
  Society	
  of	
  Clinical	
  InvesUgators	
  (Young	
  Turk)	
  
1991	
   	
   	
   Outstanding	
   InvesUgator	
   Award.	
   Department	
   of	
   Medicine	
   Fish	
   Annual	
   Research	
   Day,	
  
East	
  Carolina	
  University	
  School	
  of	
  Medicine,	
  Greenville,	
  NC,	
  1991.	
  
1992	
   	
   	
   Karl	
   Paschkis	
   Lecturer,	
   "NIDDM:	
   Lessons	
   from	
   the	
   Laboratory."	
   	
   The	
   Philadelphia	
  
Endocrine	
  Society,	
  Philadelphia,	
  Pennsylvania,	
  1992.	
  
1993	
   	
   	
   Bernardo	
   A.	
   Houssay	
   Lecturer,	
   "Insulin	
   Resistance	
   in	
   Type	
   II	
   Diabetes",	
   InternaUonal	
  
Diabetes	
  FoundaUon	
  and	
  The	
  Costa	
  Rican	
  AssociaUon	
  of	
  Endocrinology,	
  San	
  Jose,	
  Costa	
  
Rica,	
  1993.	
  
1996	
   	
   	
   Mithoffer	
  Lecturer,	
  "LepUn:	
   	
  The	
  Tale	
  of	
  an	
  Obesity	
  Gene",	
  Medical	
  University	
  of	
  South	
  
Carolina,	
  Charleston,	
  SC,	
  1996.	
  	
  
1996	
   	
   	
   Alexander	
  Marble	
  Lecturer,	
  “Obesity:	
  A	
  syndrome	
  of	
  LepUn	
  Resistance”.	
  Joslin	
  Diabetes	
  
Center.	
  	
  Harvard	
  Medical	
  School.	
  Boston,	
  Massachuseos,	
  1996.	
  
1997	
   	
   	
   BanUng	
  and	
  Best	
  Lecturer:	
  “Discovery	
  of	
  LepUn”.	
  University	
  of	
  Toronto.	
  	
  Canada	
  Diabetes	
  
AssociaUon.	
  	
  Toronto,	
  Canada,	
  1997	
  
1998	
   	
   	
   Eugene	
  Furth	
  Lecturer	
  “On	
  the	
  trail	
  to	
  cure	
  Diabetes”	
  	
  East	
  Carolina	
  University	
  School	
  of	
  
Medicine,	
  Greenville,	
  North	
  Carolina,	
  	
  1998	
  
1998	
   	
   	
   A.M.	
   Cohen	
   Memorial	
   Lecturer:	
   “On	
   the	
   Trail	
   to	
   Cure	
   Diabetes”.	
   	
   VII	
   InternaUonal	
  
Symposium	
   on	
   Insulin	
   Receptors	
   and	
   Insulin	
   AcUon:	
   Molecular	
   and	
   Clinical	
   Aspects.	
  	
  
Jerusalem,	
  Israel,	
  	
  1998	
  
1998	
   	
   	
   Recipient	
   of	
   the	
   Medal	
   of	
   Honor	
   and	
   Honorary	
   Membership	
   to	
   the	
   Real	
   Academy	
   of	
  
Medicine	
  of	
  Granada.	
  	
  Granada,	
  Spain,	
  1998	
  
1991	
  -­‐	
  2001	
   	
   The	
  third	
  most	
  highly	
  cited	
  invesUgators	
  in	
  the	
  field	
  of	
  Obesity	
  Research	
  by	
  the	
  InsUtute	
  
for	
  ScienUfic	
  InformaUon	
  (I.S.I).	
  
2000	
  -­‐	
  2012	
   	
   Member	
  of	
  the	
  AssociaUon	
  of	
  American	
  Physicians	
  (Old	
  Turk)	
  
2004	
  -­‐	
  present	
   	
   Honorary	
  Director	
  of	
  the	
  Peking	
  Diabetes	
  Center	
  and	
  Honorary	
  Professor	
  of	
  the	
  Peking	
  
University	
  Health	
  Science	
  Center.	
  	
  Peking,	
  China.	
  
2005	
   	
   	
   The	
   Leslie	
   Nicholas	
   Lecture	
   “The	
   scienUfic	
   Basis	
   of	
   New	
   Therapies	
   for	
   Obesity”.	
   The	
  
College	
  of	
  Physicians	
  of	
  Philadelphia,	
  PA	
  
	
  	
  	
  
EDITORIAL	
  ACTIVITIES	
  
1988	
  -­‐	
  1996	
   	
   Associate	
  Editor,	
  Advances	
  in	
  Diabetologia	
  
1991	
  -­‐	
  1997	
   	
   Associate	
  Editor,	
  Diabetes	
  Care	
  
1991	
  -­‐	
  2002	
   	
   Editorial	
  Board,	
  Journal	
  of	
  Clinical	
  Endocrinology	
  and	
  Metabolism	
  
1992	
  -­‐	
  2002	
   	
   SecUon	
  Editor,	
  Obesity	
  Research,	
  North	
  American	
  AssociaUon	
  for	
  the	
  Study	
  of	
  Obesity	
  
1994	
  -­‐	
  1999	
  	
   	
   Associate	
  Editor,	
  Medicina	
  y	
  Cultura	
  
1985	
  -­‐	
  2008	
   	
   Associate	
  Editor,	
  Metabolism	
  Clinical	
  and	
  Experimental	
  
2001	
  -­‐2005	
   	
   SecUon	
  Editor,	
  NutriUon	
  and	
  Obesity,	
  Endotext.com	
  
2004	
  -­‐	
  2006	
   	
   Co-­‐Editor,	
  The	
  Metabolic	
  Syndrome	
  at	
  the	
  Beginning	
  of	
  the	
  XXI	
  Century:	
  	
  A	
  GeneUc	
  and	
  
Molecular	
  Approach	
  	
  	
  
2005	
  -­‐	
  2008	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Editorial	
  Board,	
  Journal	
  of	
  Clinical	
  Endocrinology	
  and	
  Metabolism	
  
2005	
  –	
  2008	
   	
   InternaUonal	
  Editorial	
  Board,	
  Obesity	
  and	
  Metabolism	
  
CONSULTANT	
  ACTIVITIES	
  TO	
  NIH	
  
1985	
  -­‐	
  1989	
   	
   Member,	
  Metabolism	
  Study	
  SecUon,	
  NaUonal	
  InsUtutes	
  of	
  ArthriUs,	
  Diabetes	
  and	
  Kidney	
  
Diseases.	
  	
  NaUonal	
  InsUtutes	
  of	
  Health	
  
1989	
   	
   	
   Special	
  Reviewer,	
  Study	
  SecUon	
  for	
  Small	
  Business	
  InnovaUon	
  Research,	
  Pharmacology	
  
Panel,	
  NaUonal	
  InsUtutes	
  of	
  Health	
  
1989	
   	
   	
   Member,	
   Site	
   Visit	
   Team,	
   General	
   Clinical	
   Research	
   Center	
   Commioee.	
   	
   NaUonal	
  
InsUtutes	
  of	
  Health	
  
1989	
   	
   	
   Member,	
  Site	
  Visit	
  Team	
  to	
  review	
  a	
  NIH	
  General	
  Clinical	
  Research	
  Center	
  
1990	
   	
   	
   Member,	
  Clinical	
  Sciences	
  Study	
  SecUon	
  Site	
  Visit.	
  	
  NaUonal	
  InsUtutes	
  of	
  Health	
  
1991	
   	
   	
   Member,	
  NIH	
  Site	
  Visit	
  Team,	
  General	
  Clinical	
  Research	
  Center	
  
1992	
   	
   	
   Member,	
  Special	
  Review	
  Commioee,	
  NaUonal	
  InsUtute	
  of	
  General	
  Medical	
  Sciences,	
  NIH	
  
1992	
   	
   	
   Member,	
   External	
   Advisory	
   Commioee,	
   Sims'	
   Obesity	
   and	
   NutriUon	
   Research	
   Center,	
  
NIDDK	
  and	
  NICHD	
  
1992	
   	
   	
   Member,	
  NIDDK	
  Special	
  Grant	
  Review	
  Commioee	
  
1992	
   	
   	
   Chairman,	
   Diabetes	
   Endocrinology	
   Research	
   Center	
   Study	
   SecUon,	
   NIH,	
   Bethesda,	
  
Maryland	
  
1992	
   	
   	
   Member,	
  Site	
  Visit	
  Team,	
  General	
  Clinical	
  Research	
  Center,	
  NaUonal	
  InsUtute	
  of	
  Health	
  
1993	
   	
   	
   Chairman,	
   Ad	
   Hoc	
   Review	
   Group	
   SSS-­‐L	
   Clinical	
   Sciences	
   Review	
   SecUon,	
   NaUonal	
  
InsUtute	
  of	
  Health.	
  
1994	
   	
   	
   Member,	
  Behavioral	
  and	
  Neurosciences	
  Special	
  Emphasis	
  Panel,	
  NIH	
  
1995	
   	
   	
   Member,	
  Ad	
  Hoc	
  Review	
  Commioee,	
  Diabetes	
  Research	
  and	
  Training	
  Centers,	
  NaUonal	
  
InsUtute	
  of	
  Health	
  
1998	
  	
   	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Member,	
  Congressionally	
  Mandated	
  Diabetes	
  Research	
  Working	
  Group	
  and	
  Chairman	
  of	
  
the	
  Industry/Academia	
  Subgroup,	
  NaUonal	
  InsUtute	
  of	
  Health	
  (NIH).	
  
1996	
  -­‐	
  2000	
   	
   Member,	
   Subcommioee	
   B	
   of	
   the	
   Diabetes	
   and	
   DigesUve	
   and	
   Kidney	
   Diseases	
   Special	
  
Grants	
   Review	
   Commioee,	
   NaUonal	
   InsUtute	
   of	
   Diabetes	
   and	
   DigesUve	
   and	
   Kidney	
  
Diseases	
  (NIDDK),	
  NIH	
  
	
   	
   	
  
2000	
  -­‐	
  2004	
   	
   Member	
   of	
   the	
   NaUonal	
   InsUtute	
   of	
   DigesUves	
   and	
   Diabetes	
   and	
   Kidney	
   Diseases	
  
Advisory	
   Council,	
   NIH	
   and	
   Chairman	
   of	
   the	
   Concurrence	
   Grant	
   Awards	
   Approval	
  
Commioee	
  of	
  the	
  NIDDK	
  Advisory	
  Council,	
  NIH	
  
2000	
  –	
  2004	
   	
   Member	
  of	
  the	
  Disease	
  PrevenUon	
  and	
  Management	
  Working	
  Group,	
  Advisory	
  Council	
  
of	
  the	
  NaUonal	
  InsUtute	
  of	
  Diabetes	
  and	
  DigesUve	
  and	
  Kidney	
  Diseases,	
  NIH	
  
2000	
  –	
  2004	
   	
   Member	
  of	
  the	
  Advisory	
  Council	
  OperaUng	
  Procedures	
  Working	
  Group,	
  NIDDK	
  Advisory	
  
Council,	
  NIH	
   	
  
	
   	
  
CONSULTANT	
  ACTIVITIES	
  TO	
  THE	
  AMERICAN	
  DIABETES	
  ASSOCIATION	
  
1984	
  -­‐	
  1985	
   	
   Chairman,	
  PaUent	
  EducaUon	
  Commioee,	
  American	
  Diabetes	
  AssociaUon,	
  North	
  Carolina	
  
1984	
  -­‐	
  1985	
   	
   President,	
  American	
  Diabetes	
  AssociaUon,	
  Pio	
  County	
  Chapter,	
  North	
  Carolina	
  
1985	
  -­‐	
  1986	
   	
   Chairman,	
  PaUent	
  EducaUon	
  Commioee,	
  American	
  Diabetes	
  AssociaUon,	
  North	
  Carolina	
  
Affiliate	
  
1988	
  -­‐	
  1991	
   	
   Member,	
  Professional	
  EducaUon	
  Commioee,	
  American	
  Diabetes	
  AssociaUon	
  
1989-­‐1991	
   	
   Member,	
   Commioee	
   on	
   ScienUfic	
   and	
   Medical	
   Profession.	
   	
   American	
   Diabetes	
  
AssociaUon	
  
1992	
   	
   	
   Member,	
   Grant	
   Review	
   Panel,	
   Studies	
   on	
   GeneUcs	
   in	
   NIDDM,	
   American	
   Diabetes	
  
AssociaUon,	
  New	
  York,	
  NY.	
  	
  	
  
1989-­‐1991	
   	
   Master	
   Faculty,	
   Clinical	
   EducaUon	
   Program,	
   "Managing	
   Diabetes	
   in	
   the	
   1990's,"	
  
American	
  Diabetes	
  AssociaUon.	
  
1990	
  -­‐	
  1991	
   	
   President	
  Elect,	
  American	
  Diabetes	
  AssociaUon,	
  North	
  Carolina	
  Affiliate	
  
1991	
  -­‐	
  1992	
   	
   President,	
  American	
  Diabetes	
  AssociaUon,	
  North	
  Carolina	
  Affiliate	
  
1992	
  -­‐	
  1996	
   	
   Member,	
  Board	
  of	
  Directors,	
  American	
  Diabetes	
  AssociaUon,	
  Pennsylvania	
  Affiliate	
  
1992	
  -­‐	
  1996	
   	
   Member,	
   Professional	
   EducaUon	
   Commioee,	
   American	
   Diabetes	
   AssociaUon,	
  
Pennsylvania	
  Affiliate	
  
1993	
   	
   	
   Panel	
  member,	
  Consensus	
  Development	
  Conference	
  on	
  the	
  Treatment	
  of	
  Hypertension	
  
in	
  Diabetes,	
  American	
  Diabetes	
  AssociaUon	
  
1993	
  -­‐	
  1996	
   	
   Member	
  of	
  the	
  Academic	
  Steering	
  Commioee,	
  Professional	
  Diabetes	
  Academy	
  
1994	
  -­‐	
  1996	
   	
   Chairman,	
   ScienUfic	
   and	
   Medical	
   MeeUngs	
   Oversight	
   Commioee	
   of	
   the	
   American	
  
Diabetes	
  AssociaUon	
  
1994	
  -­‐	
  1996	
   	
   Member,	
  Professional	
  SecUon	
  Advisory	
  Panel	
  of	
  the	
  American	
  Diabetes	
  AssociaUon	
  
MEDICAL	
  SCHOOL	
  COMMITTEES	
  
1985	
  -­‐	
  1986	
   	
   Member,	
  Policy	
  and	
  Review	
  Commioee	
  on	
  Human	
  Research,	
  East	
  Carolina	
  University	
  
1985	
  -­‐	
  1986	
   	
   Member,	
  House	
  Staff	
  EvaluaUon	
  Commioee,	
  East	
  Carolina	
  University	
  
1985	
  -­‐	
  1991	
   	
   Member,	
  Human	
  Organ	
  Transplant	
  Commioee,	
  East	
  Carolina	
  University	
  
1985	
  -­‐	
  1991	
   	
   Member,	
   Department	
   of	
   Medicine	
   Research	
   Advisory	
   Commioee,	
   East	
   Carolina	
  
University	
  
1986	
  -­‐	
  1987	
   	
   Member,	
  RadiaUon	
  Safety	
  Commioee,	
  East	
  Carolina	
  University	
  
1986	
  -­‐	
  1987	
   	
   Member,	
  InsUtuUonal	
  Review	
  Commioee,	
  Pio	
  County	
  Memorial	
  Hospital	
  
1987	
  -­‐	
  1988	
   	
   Member,	
  Dean's	
  Search	
  Commioee	
  (Elected	
  by	
  the	
  Faculty),	
  East	
  Carolina	
  University	
  
1987	
  -­‐	
  1991	
   	
   Member,	
  Jacob	
  Furth	
  Prize	
  Commioee,	
  East	
  Carolina	
  University	
  
1989	
  -­‐	
  1990	
   	
   Chairman,	
   Ad	
   Hoc	
   Commioee,	
   Clinical	
   Research	
   Center,	
   School	
   of	
   Medicine,	
   East	
  
Carolina	
  University	
  
1989-­‐1990	
   	
   Member,	
   Ad	
   Hoc	
   Commioee,	
   Medical	
   School	
   Core	
   Laboratory	
   FaciliUes.	
   	
   School	
   of	
  
Medicine,	
  East	
  Carolina	
  University	
  
1991	
   	
   	
   Member,	
  Search	
  Commioee	
  for	
  Chairman	
  of	
  the	
  Department	
  of	
  Medicine	
  (Elected	
  by	
  
the	
  faculty),	
  East	
  Carolina	
  University	
  
1995	
  -­‐	
  1996	
   	
   Member,	
   University	
   Advisory	
   Commioee	
   on	
   InternaUonal	
   Affairs,	
   Thomas	
   Jefferson	
  
University	
  
1995	
  -­‐	
  1996	
   	
   Secretary,	
  Jefferson	
  Faculty	
  FoundaUon	
  ExecuUve	
  Commioee,	
  Jefferson	
  Medical	
  College	
  
1995	
   	
   	
   Member,	
  Jefferson	
  Faculty	
  FoundaUon	
  Finance	
  Commioee,	
  Jefferson	
  Medical	
  College	
  
OTHER	
  CONSULTANT/COMMITTEE	
  WORK	
  
1986-­‐1996	
   	
   Ad	
  Hoc	
  Reviewer,	
  Research	
  Grants	
  Program.	
  	
  Veterans	
  AdministraUon,	
  Washington,	
  DC	
  
1988	
  -­‐	
  1992	
   	
   Member	
   of	
   the	
   Medical	
   Science	
   Review	
   Commioee,	
   Juvenile	
   Diabetes	
   FoundaUon	
  
InternaUonal	
  
1989-­‐1999	
   	
   Ad	
  Hoc	
  Reviewer,	
  NaUonal	
  Science	
  FoundaUon.	
  	
  Washington,	
  DC	
  
1989-­‐1991	
   	
   Member,	
  Board	
  of	
  Medical	
  Advisors.	
  	
  Amylin	
  CorporaUon,	
  San	
  Diego,	
  CA	
  
1992	
  -­‐	
  1996	
  	
   	
   Member,	
  Board	
  of	
  Trustees,	
  Methodist	
  Hospital,	
  Philadelphia,	
  PA	
  
1992	
  -­‐	
  1996	
   	
   Member,	
  Board	
  of	
  Trustees,	
  Magee	
  RehabilitaUon	
  Hospital,	
  Philadelphia,	
  PA	
  
1992	
  -­‐	
  1996	
   	
   Member,	
  Board	
  of	
  Directors,	
  Philadelphia	
  Endocrine	
  Society	
  
1993	
  -­‐	
  1996	
   	
   Member,	
  Boston	
  Obesity/NutriUon	
  Research	
  Center	
  ScienUfic	
  Advisory	
  Group	
  
1993	
  -­‐	
  1994	
   	
   Member,	
  EducaUon	
  Commioee,	
  Professional	
  Diabetes	
  Academy	
  
1994	
  -­‐	
  1996	
   	
   Member,	
  Academic	
  Advisory	
  Commioee	
  of	
  the	
  Pfizer	
  VisiUng	
  Professorship	
  Program	
  in	
  
Diabetes	
  Management	
  
1994	
   	
   	
   Member,	
   Commioee	
   on	
   Faculty	
   and	
   Researchers,	
   Interamerican	
   College	
   of	
   Physicians	
  
and	
  Surgeons	
  
2001	
  -­‐	
  2005	
   	
   Member,	
  JDRF	
  Management	
  Advisory	
  Board	
  
2004	
  	
   	
   	
   Member,	
  American	
  Obesity	
  AssociaUon	
  Advisory	
  Board	
  
PROFESSIONAL	
  SOCIETIES/MEMBERSHIPS	
  
1976	
  -­‐2010	
   	
   Member,	
  American	
  Society	
  of	
  Internal	
  Medicine	
  
1977	
  -­‐2010	
   	
   Member,	
  American	
  College	
  of	
  Physicians	
  
1979	
  -­‐	
  2010	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Member,	
  American	
  FederaUon	
  for	
  Clinical	
  Research	
  
1980	
  -­‐	
  2010	
   	
   Member,	
  American	
  Diabetes	
  AssociaUon	
  
1980	
  -­‐	
  2010	
   	
   Member,	
  Endocrine	
  Society	
  
1984	
  -­‐	
  2010	
   	
   Member,	
  American	
  AssociaUon	
  for	
  the	
  Advancement	
  of	
  Science	
  
1984	
  -­‐	
  2010	
   	
   Member,	
  American	
  Medical	
  AssociaUon	
  
1984	
  -­‐	
  1992	
   	
   North	
  Carolina	
  Medical	
  Society	
  
1988	
  -­‐	
  2010	
   	
   Member,	
  American	
  Society	
  for	
  Clinical	
  InvesUgaUon	
  (Young	
  Turk)	
  
1991	
  -­‐	
  2010	
   	
   Member,	
  Sigma	
  Xi,	
  The	
  ScienUfic	
  Research	
  Society	
  
1992	
  -­‐	
  1997	
   	
   Pennsylvania	
  Medical	
  Society	
  
1992	
  -­‐	
  1997	
   	
   Philadelphia	
  County	
  Medical	
  Society	
  
1992	
  -­‐	
  1997	
   	
   College	
  of	
  Physicians	
  of	
  Philadelphia	
  
1992	
  -­‐	
  2010	
   	
   Charter	
  Member,	
  American	
  AssociaUon	
  of	
  Clinical	
  Endocrinologists	
  
1993	
  -­‐	
  2010	
   	
   Fellow,	
  American	
  College	
  of	
  Physicians	
  
1993	
  -­‐	
  2010	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Member,	
  North	
  American	
  AssociaUon	
  for	
  the	
  Study	
  of	
  Obesity	
  
1993	
  -­‐	
  2010	
   	
   Member,	
  Professional	
  Diabetes	
  AssociaUon	
  
1995	
  -­‐	
  2010	
   	
   Member,	
  Society	
  of	
  Ibero	
  LaUn	
  American	
  Medical	
  Professionals	
  
1996	
  -­‐	
  1997	
   	
   Member,	
  American	
  Society	
  for	
  Clinical	
  Pharmacology	
  and	
  TherapeuUcs	
  
2000	
  -­‐	
  2010	
   	
   Member,	
  AssociaUon	
  of	
  American	
  Physicians	
  (Old	
  Turk)	
  
SPECIAL	
  POST	
  GRADUATE	
  EDUCATION	
  
1992	
   	
   	
   Program	
  for	
  Chiefs	
  of	
  Clinical	
  Services,	
  Harvard	
  School	
  of	
  Public	
  Health	
  
1993	
   	
   	
   Program	
  for	
  ExecuUves	
  in	
  Managed	
  Care,	
  Harvard	
  School	
  of	
  Public	
  Health	
  
VISITING	
  PROFESSORSHIPS	
  AND	
  SPECIAL	
  LECTURES	
  
Invited	
  Speaker.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Uremia."	
  University	
  of	
  Pennsylvania.	
  Philadelphia,	
  PA,	
  1981	
  
Invited	
  Speaker.	
  "Insulin	
  Binding	
  and	
  Processing	
  in	
  Isolated	
  Rat	
  Hepatocytes."	
  University	
  of	
  Virginia.	
  Charlooesville,	
  
VA,	
  1981	
  
Invited	
  Speaker.	
  "Insulin	
  Resistance	
  in	
  Uremia."	
  University	
  of	
  South	
  Florida.	
  Tampa,	
  FL,	
  1982	
  
Invited	
  Speaker.	
  "Insulin	
  Resistance	
  in	
  Uremia."	
  Duke	
  University	
  School	
  of	
  Medicine.	
  Durham,	
  NC,	
  1982	
  
Program	
  Chairman.	
  "The	
  Diagnoses	
  and	
  Treatment	
  of	
  Type	
  II	
  Diabetes."	
  American	
  Diabetes	
  AssociaUon	
  and	
  East	
  
Carolina	
  University	
  School	
  of	
  Medicine.	
  Greenville,	
  NC,	
  1984	
  
Invited	
  Speaker.	
  "Management	
  of	
  Type	
  II	
  Diabetes."	
  At	
  the	
  "First	
  Congress	
  in	
  Washington,	
  DC	
  of	
  the	
  Interamerican	
  
College	
  of	
  Physicians	
  and	
  Surgeons."	
  Washington,	
  DC,	
  1984	
  
Invited	
  Speaker.	
  "Mechanism	
  of	
  Insulin	
  AcUon"	
  and	
  "Hyperlipidemia	
  in	
  Diabetes."	
  The	
  Third	
  Annual	
  ScienUfic	
  Panel	
  
and	
  the	
  University	
  of	
  Zulia.	
  Maracaibo,	
  Venezuela,	
  1985	
  
Invited	
  Speaker.	
  "Gastric	
  Bypass:	
  A	
  Human	
  Model	
  to	
  Study	
  Diabetes."	
  Duke	
  University	
  School	
  of	
  Medicine.	
  Durham,	
  
NC,	
  1985	
  
VisiUng	
  Professor.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  the	
  Human	
  Liver	
  from	
  PaUents	
  with	
  NIDDM."	
  University	
  of	
  
Rochester	
  School	
  of	
  Medicine	
  and	
  DenUstry.	
  Rochester,	
  NY,	
  1986	
  
Moderator.	
  "Learn	
  by	
  Sharing."	
  PaUent	
  EducaUon	
  Program	
  of	
  the	
  American	
  Diabetes	
  AssociaUon,	
  North	
  Carolina	
  
Affiliate.	
  Raleigh,	
  NC,	
  1985	
  
Invited	
   Speaker.	
   "DiabeUc	
   Emergencies"	
   and	
   "Office	
   Management	
   of	
   Type	
   II	
   Diabetes."	
   14th	
   Annual	
   Beach	
  
Workshop.	
  Myrtle	
  Beach,	
  SC,	
  1986	
  
Invited	
   Speaker.	
   "Insulin	
   Receptor	
   Kinase	
   AcUvity	
   in	
   Human	
   Liver,	
   Muscle,	
   and	
   Adipose	
   Tissue."	
   Lilly	
   Research	
  
Laboratories.	
  Indianapolis,	
  IN,	
  1986	
  
VisiUng	
  Professor.	
  "ECU	
  Diabetes	
  Program	
  Project."	
  Diabetes	
  Branch	
  of	
  the	
  NaUonal	
  InsUtutes	
  of	
  Health,	
  Bethesda,	
  
MD,	
  1986	
  
VisiUng	
  Professor.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes."	
  Geriatric	
  Research	
  Center,	
  Johns	
  Hopkins	
  
University	
  School	
  of	
  Medicine.	
  BalUmore,	
  MD,	
  1986	
  
VisiUng	
  Professor.	
  "The	
  Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes."	
  Department	
  of	
  Pathology,	
  University	
  
Complutense	
  School	
  of	
  Medicine.	
  Madrid,	
  Spain,	
  1986	
  
Invited	
  Speaker.	
  "The	
  Human	
  Endocrine	
  System:	
  A	
  Brief	
  Review."	
  At	
  the	
  Fourth	
  Annual	
  Biotechnology	
  Symposium."	
  
East	
  Carolina	
  University	
  School	
  of	
  Medicine.	
  Greenville,	
  NC,	
  1986	
  
VisiUng	
   Professor.	
   "Insulin	
   Receptor	
   Kinase	
   in	
   Important	
   Target	
   Tissues	
   for	
   Insulin	
   in	
   Type	
   II	
   Diabetes	
   Mellitus."	
  
Department	
  of	
  Medicine,	
  University	
  of	
  Rochester	
  School	
  of	
  Medicine	
  and	
  DenUstry.	
  Rochester,	
  NY,	
  1987	
  
Invited	
   Speaker.	
   "The	
   Insulin	
   Receptor	
   and	
   Liver,	
   Skeletal	
   Muscle,	
   and	
   Adipose	
   Tissue	
   from	
   Humans	
   with	
   and	
  
without	
  Type	
  II	
  Diabetes."	
  Lilly	
  Diabetes	
  Care	
  InternaUonal	
  Symposium.	
  	
  Indianapolis,	
  IN,	
  1987	
  
Invited	
   Speaker.	
   "Mechanisms	
   of	
   Insulin	
   Resistance	
   in	
   Type	
   II	
   Diabetes."	
   At	
   the	
   "NaUonal	
   InsUtutes	
   of	
   Health	
  
Centennial,	
  Nurturing	
  CreaUve	
  Research	
  Genius	
  for	
  Biomedicine."	
  Duke	
  University	
  School	
  of	
  Medicine.	
  Durham,	
  
NC,	
  1987	
  
Symposium	
   Chairman.	
   "Diabetes	
   Mellitus:	
   Management	
   in	
   Pregnancy	
   and	
   Childhood."	
   American	
   Diabetes	
  
AssociaUon	
  and	
  East	
  Carolina	
  University	
  School	
  of	
  Medicine.	
  Greenville,	
  NC,	
  1987	
  
Invited	
  Speaker.	
  "Type	
  II	
  Diabetes	
  Mellitus:	
  Treatment	
  and	
  ComplicaUons."	
  The	
  XI	
  Interamerican	
  Medical	
  Congress	
  
of	
  the	
  Spanish-­‐American	
  Medical	
  Society.	
  New	
  York,	
  NY,	
  1987	
  
VisiUng	
  Professor.	
  "Mechanisms	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes."	
  University	
  of	
  Virginia	
  Diabetes	
  Center,	
  
Charlooesville,	
  VA,	
  1987	
  
VisiUng	
   Professor.	
   "Role	
   of	
   Insulin	
   Receptor	
   Tyrosine	
   Kinase	
   in	
   Insulin	
   Resistance."	
   Glaxo	
   Research	
   Laboratory.	
  
Research	
  Triangle	
  Park,	
  NC,	
  1987	
  
Invited	
   Speaker.	
   "Advances	
   in	
   the	
   Treatment	
   of	
   Type	
   II	
   Diabetes."	
   At	
   the	
   XII	
   Annual	
   Conference	
   of	
   the	
   North	
  
Carolina	
  Academy	
  of	
  Physicians."	
  Wrightsville,	
  NC,	
  1988	
  
Invited	
   Speaker.	
   "Carbohydrate	
   Metabolism	
   in	
   Diabetes."	
   At	
   the	
   "IX	
   Annual	
   Congress	
   of	
   the	
   Spanish	
   Society	
   of	
  
Diabetes."	
  Barcelona,	
  Spain,	
  1988	
  
Invited	
  Speaker.	
  "Current	
  Views	
  of	
  EUology	
  of	
  Type	
  II	
  Diabetes:	
  Are	
  We	
  Gewng	
  There?"	
  At	
  "Diabetes	
  Update	
  1988."	
  
American	
  Diabetes	
  AssociaUon	
  and	
  East	
  Carolina	
  University	
  School	
  of	
  Medicine.	
  Southern	
  Pines,	
  NC,	
  1988	
  
Invited	
  Speaker.	
  "The	
  Insulin	
  Receptor	
  in	
  Obesity	
  and	
  NIDDM:	
  A	
  New	
  Target	
  for	
  Clinical	
  and	
  Basic	
  Research."	
  At	
  a	
  
symposium	
  on	
  the	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes"	
  70th	
  Annual	
  MeeUng	
  of	
  the	
  Endocrine	
  
Society.	
  New	
  Orleans,	
  LA,	
  1988	
  
VisiUng	
   Professor	
   and	
   Clinical	
   Scholar.	
   Lilly	
   task	
   force	
   on	
   "Early	
   RecogniUon	
   and	
   PrevenUon	
   of	
   Diabetes."	
   Lilly	
  
Research	
  Laboratories.	
  Indianapolis,	
  IN,	
  1988	
  
Invited	
  Speaker.	
  "DiabeUc	
  Emergencies."	
  North	
  Carolina	
  Family	
  Physician's	
  Annual	
  MeeUng.	
  Wrightsville	
  Beach,	
  NC,	
  
1988	
  
Invited	
   Speaker.	
   "Diabetes."	
   Geriatric	
   Medicine	
   Board	
   Review.	
   East	
   Carolina	
   University	
   School	
   of	
   Medicine.	
  
Greenville,	
  NC,	
  1988	
  
VisiUng	
  Professor.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes."	
  Veterans	
  AdministraUon	
  Medical	
  Center	
  at	
  
Georgetown	
  University.	
  Washington,	
  DC,	
  1988	
  
Invited	
   Speaker.	
   "Insulin	
   Receptor	
   Kinase	
   AlteraUons."	
   At	
   the	
   "AcUon	
   of	
   Insulin	
   and	
   Related	
   Growth	
   Factors	
   in	
  
Diabetes	
   Mellitus."	
   CelebraUng	
   Joslin's	
   90th	
   Anniversary.	
   Joslin	
   Diabetes	
   Center	
   and	
   Harvard	
   Medical	
   School.	
  
Boston,	
  MA,	
  1988	
  
VisiUng	
  Professor.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes."	
  University	
  of	
  Illinois	
  Chicago,	
  IL,	
  1988	
  
VisiUng	
  Professor.	
  "Insulin	
  Resistance."	
  University	
  of	
  California,	
  San	
  Diego,	
  CA,	
  1988	
  
Invited	
  Speaker.	
  "DevastaUon	
  of	
  the	
  Disease:	
  Type	
  II	
  Diabetes."	
  Third	
  Hispanic	
  Medical	
  Congress.	
  Washington,	
  DC,	
  
1988	
  
VisiUng	
  Professor.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes"	
  and	
  "Chronic	
  ComplicaUons	
  of	
  Diabetes."	
  
Diabetes	
  Branch	
  of	
  the	
  NaUonal	
  InsUtutes	
  of	
  Health.	
  Bethesda,	
  MD,	
  1988	
  
VisiUng	
  Professor.	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes"	
  and	
  "Chronic	
  ComplicaUons	
  of	
  Diabetes."	
  
University	
  of	
  Colorado	
  Health	
  Sciences	
  Center.	
  Denver,	
  Colorado,	
  1988	
  
VisiUng	
   Professor.	
   "Mechanism	
   of	
   Insulin	
   Resistance	
   in	
   Type	
   II	
   Diabetes."	
   Diabetes	
   Clinical	
   Research	
   InsUtute,	
  
Charlooesville,	
  VA,	
  1989	
  
VisiUng	
  Professor.	
  "The	
  Insulin	
  Receptor:	
  A	
  New	
  Target	
  For	
  Basic	
  and	
  Clinical	
  InvesUgaUons."	
  Research	
  Seminar,	
  
Emory	
  University,	
  Atlanta,	
  GA,	
  1989	
  
VisiUng	
   Professor.	
   "Mechanism	
   of	
   Insulin	
   Resistance	
   in	
   Type	
   II	
   Diabetes."	
   Diabetes	
   Center	
   of	
   Eastern	
   Virginia,	
  
Norfolk,	
  VA,	
  1989	
  
Invited	
  Speaker.	
  "Mechanism	
  of	
  Insulin	
  AcUon."	
  Inter-­‐University	
  Post-­‐Graduate	
  course	
  on	
  Molecular	
  Mechanism	
  of	
  
the	
  Endocrine	
  System,	
  Fundacion	
  Ramon	
  Areces,	
  Madrid,	
  Spain,	
  1989	
  
Keynote	
  Speaker.	
  "The	
  Pathogenesis	
  of	
  Obesity"	
  and	
  "Meet	
  the	
  Professor:	
  Problem	
  Case	
  Discussion."	
  At	
  Diabetes	
  
Mellitus	
  -­‐	
  Challenges	
  in	
  the	
  1990's."	
  American	
  Diabetes	
  AssociaUon,	
  Hilton	
  Head	
  Island,	
  SC,	
  1989	
  
Invited	
   Speaker.	
   "Clinical	
   and	
   Physiological	
   Correlates	
   of	
   Glucose	
   Transport	
   in	
   Obesity	
   and	
   Diabetes"	
   at	
   "The	
  
Symposium	
  in	
  FronUers	
  in	
  the	
  Molecular	
  and	
  Cellular	
  Biology	
  and	
  Glucose	
  Transport."	
  49th	
  Annual	
  MeeUng	
  and	
  
ScienUfic	
  Sessions,	
  American	
  Diabetes	
  AssociaUon,	
  1989	
  
Invited	
  Speaker.	
  "Insulin	
  Resistance	
  in	
  Obesity:	
  Towards	
  a	
  Molecular	
  Approach."	
  UCLA	
  Symposium	
  on	
  Molecular	
  
and	
  Cellular	
  Biology,	
  Keystone,	
  Colorado,	
  1989	
  
Keynote	
   Speaker.	
   "Advances	
   in	
   Diabetes	
   Mellitus"	
   at	
   the	
   Mexican	
   Society	
   of	
   NutriUon	
   and	
   Endocrinology,	
  
Monterey,	
  Mexico,	
  1989	
  
Keynote	
  Speaker.	
  "Obesity	
  and	
  Insulin	
  Resistance"	
  and	
  "Meet	
  the	
  Professor:	
  Diabetes	
  Mellitus	
  and	
  Hypertension"	
  
at	
  the	
  IV	
  InternaUonal	
  Congress	
  of	
  Medicine,	
  Victoria,	
  Mexico,	
  1989	
  
Invited	
  Speaker.	
  "Studies	
  on	
  the	
  Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes."	
  Merck,	
  Sharp,	
  &	
  Dohme	
  Co.	
  
Rahway,	
  NJ,	
  1989	
  
Invited	
   Speaker.	
   "The	
   Insulin	
   Receptor	
   and	
   Post	
   Receptor	
   in	
   Liver	
   in	
   NIDDM:	
   Effects	
   of	
   Sulfonylureas."	
   Fourth	
  
InternaUonal	
  Conference	
  on	
  Diabetes.	
  University	
  of	
  Virginia,	
  Charlooesville,	
  VA,	
  1989	
  
Keynote	
  Speaker.	
  "Cellular	
  AlteraUons	
  in	
  Liver,	
  Muscle,	
  and	
  Adipose	
  Tissues	
  Responsible	
  for	
  Insulin	
  Resistance	
  in	
  
Diabetes."	
   MeeUng	
   of	
   the	
   Diabetes	
   Treatment	
   Centers	
   of	
   American	
   FoundaUon.	
   1989	
   Annual	
   Physicians	
  
Conference.	
  Palm	
  Desert,	
  CA,	
  1989	
  
Invited	
  Speaker.	
  "Diabetes	
  is	
  a	
  Serious	
  Disease"	
  42nd	
  Annual	
  ScienUfic	
  Assembly	
  of	
  the	
  North	
  Carolina	
  Academy	
  of	
  
Family	
  Physicians.	
  Greensboro,	
  NC,	
  1990	
  
Invited	
   Speaker.	
   "Cellular	
   AlteraUons	
   in	
   Liver,	
   Muscle,	
   and	
   Adipose	
   Tissue	
   Responsible	
   for	
   Insulin	
   Resistance	
   in	
  
NIDDM."	
  Hershey	
  Medical	
  Center,	
  Hershey,	
  PA,	
  1990	
  
Invited	
  Speaker.	
  "AlteraUons	
  in	
  Insulin	
  Receptors	
  and	
  Glucose	
  Transporters	
  in	
  Obese	
  and	
  DiabeUc	
  Humans,"	
  at	
  the	
  
Satellite	
  MeeUng	
  of	
  the	
  XI	
  Amsterdam	
  InternaUonal	
  Congress	
  of	
  Pharmacology,	
  "Pathophysiology	
  and	
  Treatment	
  of	
  
Diabetes	
  Mellitus"	
  Montpellier,	
  France,	
  1990	
  
Invited	
  Speaker.	
  "Altered	
  Coupling	
  of	
  the	
  Insulin	
  Receptor	
  with	
  Gi	
  Protein	
  in	
  the	
  Liver	
  from	
  PaUents	
  with	
  NIDDM"	
  at	
  
the	
  InternaUonal	
  Symposium	
  on	
  Obesity	
  and	
  Diabetes	
  Mellitus,	
  Nagoya,	
  Japan,	
  1990	
  
Invited	
   Speaker.	
   "Insulin	
   AcUon	
   in	
   Adipose	
   Tissue	
   and	
   Muscle	
   in	
   Human	
   Obesity	
   and	
   Diabetes"	
   at	
   the	
   6th	
  
InternaUonal	
  Congress	
  on	
  Obesity,	
  Kobe,	
  Japan,	
  1990	
  
Invited	
  Speaker,	
  "Diagnosis	
  and	
  Treatment	
  of	
  Diabetes	
  Mellitus"	
  and	
  "Insulin	
  Resistance	
  in	
  Obesity	
  and	
  Diabetes	
  
Mellitus"	
  at	
  the	
  LII	
  NaUonal	
  Medical	
  Congress,	
  San	
  Jose,	
  Costa	
  Rica,	
  1990	
  
Invited	
  Speaker,	
  "Post-­‐Receptor	
  Defect	
  in	
  Type	
  II	
  Diabetes"	
  American	
  Diabetes	
  AssociaUon,	
  Minneapolis	
  Affiliate,	
  
Minneapolis,	
  MN,	
  1990	
  
Invited	
  Speaker,	
  "G-­‐Proteins	
  in	
  Diabetes"	
  at	
  the	
  Mayo	
  Clinic,	
  Rochester,	
  NY,	
  1990	
  
Invited	
   Speaker,	
   "Overview	
   of	
   AlteraUons	
   in	
   Insulin	
   AcUon	
   in	
   Human	
   Diabetes"	
   at	
   the	
   UCLA	
   Symposium	
   on	
  
Molecular	
  and	
  Cellular	
  Biology,	
  Park	
  City,	
  Utah,	
  1991	
  
Invited	
  Speaker,	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  NIDDM."	
  Miles	
  Laboratories,	
  West	
  Haven,	
  ConnecUcut,	
  1991	
  
Invited	
  Speaker,	
  "Mechanisms	
  and	
  Management	
  of	
  Type	
  II	
  Diabetes."	
  New	
  Mexico	
  Metabolism	
  Symposium	
  1991.	
  
Taos,	
  New	
  Mexico,	
  1991	
  
Invited	
  Speaker,	
  "Mechanism	
  of	
  Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes.	
  "Baylor	
  College	
  of	
  Medicine,	
  Houston,	
  Texas,	
  
1991	
  
Invited	
  Speaker,	
  "Diabetes	
  Mellitus	
  PrevenUon	
  in	
  the	
  High	
  Risk	
  PaUent,"	
  at	
  the	
  "Current	
  Advances	
  in	
  NutriUonal	
  
Medicine	
  and	
  Disease	
  PrevenUon."	
  Harvard	
  Medical	
  School,	
  Boston,	
  MA,	
  1991	
  
Invited	
  Speaker,	
  "NIDDM:	
  Insulin	
  Resistance	
  vs.	
  Insulin	
  SecreUon."	
  NJ	
  Affiliate	
  of	
  the	
  ADA,	
  Jamesburg,	
  NJ,	
  1991	
  
Keynote	
  Speaker,	
  "Diabetes	
  in	
  the	
  90's."	
  American	
  Diabetes	
  AssociaUon,	
  NC	
  Affiliate,	
  Raleigh,	
  NC,	
  1991	
  
Invited	
  Speaker,	
  "Insulin	
  Resistance	
  in	
  NIDDM."	
  University	
  of	
  Chicago,	
  Chicago,	
  IL,	
  1991	
  
Invited	
  Speaker,	
  "Carbohydrate	
  Metabolism	
  in	
  Obesity	
  and	
  Diabetes."	
  NutriUon	
  and	
  Diabetes	
  Mellitus:	
  Focus	
  for	
  
the	
  1990's.	
  A	
  Satellite	
  Symposium	
  of	
  the	
  14th	
  IDF	
  Congress.	
  BalUmore,	
  MD,	
  1991	
  
Invited	
   Speaker,	
   "Physiology	
   of	
   Insulin	
   AcUon	
   in	
   Muscle."	
   14th	
   InternaUonal	
   Diabetes	
   FederaUon	
   Congress,	
  
Washington,	
  DC,	
  1991	
  
Invited	
  Speaker,	
  "Mechanism	
  of	
  Insulin	
  AcUon."	
  Satellite	
  Symposium,	
  14th	
  IDF	
  Congress,	
  Airily,	
  VA,	
  1991	
  
VisiUng	
   Professor,	
   "Cellular	
   AlteraUons	
   in	
   Liver,	
   Skeletal	
   Muscle,	
   and	
   Adipose	
   Tissue	
   Responsible	
   for	
   Insulin	
  
Resistance	
  in	
  Obesity	
  and	
  Type	
  II	
  Diabetes."	
  Symposium	
  organized	
  by	
  the	
  USSR	
  Academy	
  of	
  Medical	
  Sciences	
  and	
  
the	
  USSR	
  Ministry	
  of	
  Health,	
  Moscow,	
  Russia,	
  1991	
  
Invited	
   Speaker,	
   "The	
   IGF-­‐1	
   Receptor	
   in	
   NIDDM:	
   A	
   Pathway	
   to	
   Bypass	
   Insulin	
   Resistance?"	
   39th	
   Annual	
   Clinical	
  
Society	
  ScienUfic	
  MeeUng	
  of	
  the	
  American	
  Diabetes	
  AssociaUon,	
  New	
  York	
  Downstate	
  Affiliate,	
  New	
  York	
  City,	
  1991	
  
Invited	
   Speaker,	
   "Mechanism	
   of	
   Insulin	
   Resistance	
   in	
   Obesity."	
   Workshop	
   sponsored	
   by	
   the	
   NaUonal	
   Diabetes	
  
Advisory	
  Board,	
  NaUonal	
  InsUtutes	
  of	
  Health,	
  Arlington,	
  VA,	
  1991	
  
Invited	
  Speaker,	
  "Syndrome	
  X."	
  	
  11th	
  Annual	
  Day	
  of	
  Diabetes,	
  American	
  Diabetes	
  AssociaUon,	
  Columbus,	
  Georgia,	
  
1992	
  
Invited	
  Speaker,	
  "Insulin	
  Resistance	
  in	
  Obesity	
  and	
  Non-­‐Insulin	
  Dependent	
  Diabetes:	
   	
  Cause	
  or	
  Effect."	
   	
  Western	
  
Metabolism	
  Club,	
  Carmel,	
  California,	
  1992	
  
VisiUng	
   Professor,	
   	
   "Fat	
   1992",	
   Grand	
   Rounds,	
   Hospital	
   of	
   the	
   University	
   of	
   Pennsylvania,	
   Philadelphia,	
  
Pennsylvania,	
  1992	
  
Invited	
  Speaker,	
  "Alteraciones	
  a	
  nivel	
  de	
  receptor	
  y	
  post	
  receptor	
  en	
  la	
  obesidad,"	
  XXV	
  Congreso	
  Nacional	
  de	
  la	
  
Sociedad	
  Española	
  de	
  Ciencias	
  Fisiológicas,	
  Cordoba,	
  Spain,	
  1992	
  
Keynote	
  Speaker,	
  "Aspectos	
  moleculares	
  de	
  la	
  diabetes	
  mellitus	
  no	
  insulinodependiente",	
  VIII	
  Congreso	
  Asociación	
  
LaUnoamericana	
  de	
  Diabetes,	
  Buenos	
  Aires,	
  ArgenUna,	
  1992	
  
Simposium	
  Speaker,	
  "Resistencia	
  insulinica:	
  su	
  rol	
  en	
  diversos	
  síndromes,"	
  VII	
  Congreso	
  Asociación	
  LaUnoamericana	
  
de	
  Diabetes,	
  Buenos	
  Aires,	
  ArgenUna,	
  1992	
  
VisiUng	
  Professor,	
  "Weight	
  Loss:	
   	
  Is	
  it	
  a	
  Miracle?",	
  Cooper	
  Hospital/University	
  of	
  Medicine	
  and	
  DenUstry	
  of	
  New	
  
Jersey,	
  Robert	
  Wood	
  Johnson	
  Medical	
  School,	
  Camden,	
  New	
  Jersey,	
  1992	
  
VisiUng	
  Professor,	
  "Insulin	
  Resistance	
  in	
  Type	
  II	
  Diabetes",	
  University	
  of	
  Piosburgh,	
  Piosburgh,	
  Pennsylvania,	
  1992	
  
VisiUng	
  Professor,	
  "Pharmacological	
  methods	
  to	
  bypass	
  insulin	
  resistance",	
  Department	
  of	
  Biochemistry,	
  University	
  
of	
  Medicine	
  and	
  DenUstry	
  of	
  New	
  Jersey/School	
  of	
  Osteopathic	
  Medicine,	
  Stralord,	
  New	
  Jersey,	
  1992	
  
Invited	
   Speaker,	
   "Insulin	
   Resistance	
   in	
   Type	
   II	
   Diabetes",	
   InternaUonal	
   Diabetes	
   FederaUon	
   Congress	
   and	
   the	
  
Dominican	
  Republic	
  AssociaUon	
  of	
  Endocrinology,	
  Santo	
  Domingo,	
  Dominican	
  Republic,	
  1993	
  
VisiUng	
  Professor,	
  "Insulin	
  Resistance",	
  State	
  University	
  of	
  New	
  York	
  Health	
  Science	
  Center	
  at	
  Brooklyn,	
  Brooklyn,	
  
New	
  York,	
  1993	
  
VisiUng	
   Professor,	
   "Insulin	
   Resistance:	
   	
   A	
   target	
   for	
   the	
   Clinical	
   and	
   Basic	
   InvesUgator",	
   The	
   Milton	
   S.	
   Hershey	
  
Medical	
  Center	
  of	
  the	
  Pennsylvania	
  State	
  University,	
  Hershey,	
  Pennsylvania,	
  1993	
  
Invited	
   Speaker,	
   "Beyond	
   the	
   Basics:	
   	
   Neuropathy",	
   the	
   13th	
   Annual	
   Diabetes	
   Update	
   '93	
   -­‐	
   American	
   Diabetes	
  
AssociaUon,	
  Philadelphia,	
  Pennsylvania,	
  1993	
  
Invited	
  Speaker,	
  "Obesity:	
   	
  A	
  Disease	
  of	
  the	
  Adipose	
  Tissue",	
  NaUonal	
  InsUtutes	
  of	
  Health,	
  Bethesda,	
  Maryland,	
  
1993	
  
Invited	
  Speaker,	
  "The	
  ABCs	
  of	
  Thyroid	
  Disease",	
  Eastern	
  Shore	
  Medical	
  Symposium,	
  Rehoboth	
  Beach,	
  Delaware,	
  
1993	
  	
  
VisiUng	
   Professor,	
   "Gene	
   Therapy	
   for	
   Insulin	
   Resistance",	
   Department	
   of	
   Biochemistry,	
   School	
   of	
   Medicine,	
  
Universidad	
  Complutense,	
  Madrid,	
  Spain,	
  1993	
  
Keynote	
  Speaker,	
  "Diabetes	
  in	
  LaUnos"	
  8th	
  Hispanic	
  Medical	
  Congress.	
  	
  The	
  Interamerican	
  College	
  of	
  Physicians	
  and	
  
Surgeons,	
  San	
  Juan,	
  Puerto	
  Rico,	
  1993	
  	
  
Invited	
  Speaker,	
  "The	
  TranslaUon	
  of	
  the	
  DCCT	
  to	
  the	
  Care	
  of	
  PaUents	
  with	
  Type	
  II	
  Diabetes	
  Mellitus"	
  The	
  Opening	
  
Symposium	
  of	
  the	
  Joslin	
  Center	
  for	
  Diabetes	
  at	
  Jefferson	
  Medical	
  College	
  and	
  Wills	
  Eye	
  Hospital,	
  Philadelphia,	
  1994	
  
Invited	
   Speaker,	
   "Weight	
   Loss	
   in	
   Severely	
   Obese	
   Subjects	
   Prevents	
   Type	
   II	
   Diabetes"	
   	
   InternaUonal	
   Symposium	
  
sponsored	
  by	
  the	
  Chinese	
  NutriUon	
  Society	
  and	
  Shanghai	
  NutriUon	
  Society.	
  	
  Beijing,	
  China,	
  1994	
  
Invited	
  Speaker,	
  "Thyroid	
  Nodules"	
  Diabetes-­‐Endocrine	
  Symposium,	
  Medical	
  College	
  of	
  Pennsylvania,	
  Philadelphia,	
  
Pennsylvania,	
  1994	
  
Leadership	
   Workshop:	
   	
   "TherapeuUc	
   Choices	
   in	
   NIDDM”	
   54th	
   Annual	
   MeeUng,	
   American	
   Diabetes	
   AssociaUon,	
  
New	
  Orleans,	
  1994	
  
Invited	
   Speaker,	
   "Morbid	
   Obesity	
   and	
   Diabetes"	
   7th	
   InternaUonal	
   Congress	
   of	
   Obesity	
   Satellite	
   Symposium	
   on	
  
Surgical	
  Treatment	
  of	
  Obesity,	
  Montreal,	
  Quebec,	
  Canada,	
  1994	
  
Keynote	
  Speaker,	
  "Insulin	
  Resistance	
  from	
  the	
  laboratory	
  to	
  the	
  bedside",	
  XVI	
  Internal	
  Medicine	
  Chilean	
  Congress,	
  
SanUago,	
  Chile,	
  1994	
  
Symposium	
  Speaker,	
  "Current	
  and	
  future	
  treatment	
  of	
  Diabetes	
  Mellitus",	
  XVI	
  Internal	
  Medicine	
  Chilean	
  Congress,	
  
SanUago,	
  Chile,	
  1994	
  
Invited	
  Speaker,	
  "PrevenUon	
  of	
  diabetes:	
  	
  Is	
  it	
  possible?	
  ",	
  XVI	
  Internal	
  Medicine	
  Chilean	
  Congress,	
  SanUago,	
  Chile,	
  
1994	
  
Invited	
  Speaker,	
  "Insulin	
  Analogs"	
  American	
  Diabetes	
  AssociaUon,	
  Northern	
  Illinois	
  Affiliate’s	
  Thirty-­‐Seventh	
  Annual	
  
Professional	
  Symposium,	
  Chicago,	
  1994	
  
Invited	
  Speaker,	
  "The	
  TranslaUon	
  of	
  the	
  DCCT	
  to	
  the	
  Care	
  of	
  the	
  PaUent	
  with	
  Type	
  II	
  Diabetes	
  Mellitus",	
  The	
  Third	
  
Annual	
  Controversies	
  in	
  Ambulatory	
  Care	
  Medicine,	
  Philadelphia,	
  1994	
  
VisiUng	
  Professor,	
  "PrevenUon	
  of	
  Type	
  II	
  Diabetes:	
   	
  The	
  Challenge	
  of	
  the	
  Next	
  Decade",	
  Medical	
  Grand	
  Rounds,	
  
UMDNJ-­‐Robert	
  Wood	
  Johnson	
  Medical	
  School,	
  New	
  Brunswick,	
  NJ,	
  1995	
  
VisiUng	
  Professor,	
  “The	
  PromoUon	
  of	
  the	
  Adipocyte:	
  	
  from	
  storage	
  to	
  an	
  endocrine	
  cell”,	
  Grand	
  Rounds,	
  University	
  
of	
  Southern	
  California	
  School	
  of	
  Medicine,	
  Los	
  Angeles,	
  CA,	
  1995	
  
VisiUng	
   Professor,	
   “¿Es	
   el	
   adiosito	
   inteligente?”,	
   Consejo	
   Superior	
   de	
   InvesUgaciones	
   Cien~ficas,	
   Madrid,	
   Spain,	
  
1995	
  
Leadership	
  Workshop:	
  	
  "Insulin	
  AcUon	
  Enhancers”,	
  55th	
  Annual	
  MeeUng,	
  American	
  Diabetes	
  AssociaUon,	
  Atlanta,	
  
Georgia,	
  1995	
  
Invited	
  Speaker,	
  “Impact	
  of	
  weight	
  loss	
  by	
  surgery	
  on	
  metabolic	
  fitness”,	
  FASEB	
  Summer	
  Conference	
  on	
  GeneUc	
  and	
  
Behavioral	
  Influences	
  on	
  Nutrient	
  Metabolism	
  and	
  Obesity,	
  Copper	
  Mountain,	
  Colorado,	
  1995	
  
VisiUng	
  Professor,	
  “Ob	
  protein	
  resistance	
  in	
  human	
  obesity”,	
  University	
  of	
  Chicago,	
  Chicago,	
  Illinois,	
  1995	
  
Plenary	
  Speaker,	
  “Studies	
  of	
  LepUn	
  in	
  Human	
  Subjects”,	
  NAASO	
  MeeUng,	
  Baton	
  Rouge,	
  Louisiana,	
  1995	
  
Symposium	
  Speaker,	
  “The	
  Gut	
  and	
  NIDDM”,	
  Precose	
  Specialist	
  InvesUgator	
  MeeUng,	
  Lincolnshire,	
  IL,	
  1995	
  
VisiUng	
  Professor,	
  “¿Terapia	
  molecular	
  de	
  la	
  diabetes	
  o	
  de	
  la	
  obesidad?”,	
  V	
  Congreso	
  de	
  Ciencias	
  FarmacéuUcas,	
  
Madrid,	
  Spain,	
  1995	
  
Symposium	
   Speaker,	
   “Obesidad	
   e	
   insulino	
   resistencia”,	
   Sociedad	
   Mexicana	
   de	
   Nutrición	
   y	
   Endocrinologia,	
  
Guanajuato,	
  Mexico,	
  1995	
  
Symposium	
  Speaker,	
  “LepUn:	
  	
  The	
  sensor	
  of	
  either	
  fact	
  mass	
  or	
  energy	
  balance?”,	
  American	
  Society	
  for	
  Parenteral	
  
and	
  Enteral	
  NutriUon,	
  Washington,	
  DC,	
  1996	
  
Symposium	
  Speaker,	
  “Advances	
  en	
  Fisiopatologia	
  de	
  la	
  Obesidad”,	
  Canary	
  Islands,	
  Spain,1996	
  
Invited	
  Speaker,	
  “The	
  Ob	
  Gene	
  in	
  Human	
  Obesity”,	
  Western	
  Metabolism	
  Club,	
  Carmel,	
  CA,	
  1996	
  
Invited	
  Speaker,	
  “Ob	
  Protein	
  in	
  Human	
  Obesity”,	
  IBC’s	
  Second	
  Annual	
  InternaUonal	
  Symposium,	
  Washington,	
  DC,	
  
1996	
  
Invited	
   Speaker,	
   “New	
   Insights	
   into	
   the	
   Pathophysiology	
   and	
   Therapy	
   of	
   Obesity:	
   	
   The	
   LepUn	
   Story”,	
   Sixteenth	
  
MeeUng	
  of	
  the	
  InternaUonal	
  ScienUfic	
  Commioee	
  on	
  Diabetes,	
  Cologne,	
  Germany,	
  1996	
  
Invited	
   Speaker,	
   “Obesity:	
   	
   A	
   GeneUc	
   Disease?”,	
   Fourth	
   ScienUfic	
   Course	
   in	
   PancreaUc	
   Islet	
   Physiology	
   and	
  
Pathology,	
  Barcelona,	
  Spain,	
  1996	
  
Invited	
  Speaker,	
  “Obesity:	
  	
  What	
  Can	
  be	
  Done?”,	
  Clinical	
  Endocrinology,	
  Harvard	
  Medical	
  School,	
  Boston,	
  MA,	
  1996	
  
Invited	
   Speaker,	
   "Human	
   Obesity:	
   	
   What	
   Have	
   We	
   Learned	
   from	
   Recent	
   GeneUc	
   Insights?",	
   	
   Biomedicine	
   '96,	
  
Washington,	
  D.C.,	
  1996	
  
VisiUng	
  Professor,	
  "LepUn:	
  	
  The	
  Tale	
  of	
  an	
  Obesity	
  Gene,	
  Part	
  II:	
  	
  Rx:	
  	
  LepUn	
  Sc,	
  qday	
  and	
  eat	
  anything	
  you	
  want	
  ,	
  
East	
  Carolina	
  University,	
  Greenville,	
  NC,	
  1996	
  
Invited	
   speaker,	
   "LepUn	
   Physiology	
   and	
   Pathophysiology	
   in	
   Man",	
   American	
   Society	
   for	
   Clinical	
   InvesUgaUon,	
  
Washington,	
  D.C.,	
  1996	
  
Symposium	
  Speaker,	
  "Molecular	
  therapy	
  of	
  obesity	
  or	
  diabetes?	
  	
  That	
  is	
  the	
  quesUon",	
  XIII	
  MeeUng	
  of	
  the	
  Spanish	
  
Diabetes	
  Society,	
  Oviedo,	
  Spain,	
  1996	
  
Keynote	
  speaker,	
  "LepUn:	
  	
  The	
  tale	
  of	
  an	
  obesity	
  gene:	
  American	
  Diabetes	
  AssociaUon,	
  Amelia	
  Island,	
  Florida,	
  1996	
  
Symposium	
  Speaker:	
  “Obesity	
  and	
  Diabetes”	
  4th	
  Annual	
  Congress	
  on	
  Women’s	
  Health,	
  Washington,	
  D.C.,	
  1996	
  
Invited	
  Speaker,	
  “LepUn:	
  The	
  Tale	
  of	
  an	
  Obesity	
  Gene”	
  Annual	
  Research	
  Symposium,	
  The	
  InsUtute	
  of	
  NutriUon,	
  
University	
  of	
  North	
  Carolina,	
  Chapel	
  Hill,	
  NC,	
  1996	
  
Invited	
   Speaker,	
   “Ob	
   Protein	
   in	
   Human	
   Obesity”	
   	
   IBC’s	
   Third	
   InternaUonal	
   Symposium	
   -­‐	
   Obesity	
   -­‐	
   Advances	
   in	
  
Understanding	
  and	
  Treatment.	
  San	
  Diego,	
  CA,	
  1996	
  
Invited	
  Speaker,	
  “MeeUng	
  the	
  Needs	
  of	
  paUents:	
  Emerging	
  OpUons	
  in	
  Diabetes	
  Care”.	
  	
  34th	
  Annual	
  MeeUng	
  of	
  the	
  
European	
  AssociaUon	
  for	
  the	
  Study	
  of	
  Diabetes.	
  Vienna,	
  Austria,	
  1996	
  
Invited	
  Speaker.	
  “Obesity	
  as	
  a	
  Metabolic	
  Disease”.	
  	
  6th	
  Annual	
  Turamberry	
  Conference.	
  Aventura,	
  Florida,	
  1996	
  
Invited	
   Speaker.	
   	
   “The	
   ob	
   Gene	
   Product	
   and	
   Nutrient	
   Balance”.	
   North	
   American	
   AssociaUon	
   for	
   the	
   Study	
   of	
  
Obesity.	
  Breckenridge,	
  Colorado,	
  1996	
  
Invited	
  Speaker.	
  	
  XXVI	
  Congreso	
  de	
  la	
  Asociación	
  Española	
  de	
  Pediatria.	
  Valencia,	
  Spain,	
  1996	
  
Invited	
  Speaker.	
  	
  Human	
  Obesity:	
  Beyond	
  LepUn	
  ProducUon.	
  InternaUonal	
  Congress	
  on	
  AnU-­‐Obesity	
  Drug	
  Targets.	
  
Cambridge,	
  MA.,	
  1996	
  
Invited	
   Speaker.	
   	
   Insulina	
   y	
   lepUna:	
   La	
   Extraña	
   Pareja.	
   VIII	
   Congreso	
   Sociedad	
   Valenciana	
   de	
   Endocrinologia,	
  
Diabetes	
  y	
  nutrición.	
  Valencia,	
  Spain,	
  1996	
  	
  
Invited	
  Speaker.	
   	
  Chapter	
  One	
  in	
  the	
  Story	
  of	
  LepUn	
  in	
  Humans.	
  American	
  Society	
  for	
  Clinical	
  Pharmacology	
  and	
  
TherapeuUcs.	
  San	
  Diego,	
  CA,	
  1997	
  
Invited	
  Speaker.	
   	
  “Pathophysiology	
  of	
  Obesity”.	
   	
  Symposium	
  of	
  the	
  German	
  Endocrine	
  Society.	
  Lübeck,	
  Germany,	
  
1997.	
  
Invited	
   Speaker.	
   	
   “LepUn:	
   The	
   Second	
   Year”.	
   	
   2nd	
   World	
   Conference	
   of	
   the	
   InternaUonal	
   Society	
   for	
   Molecular	
  
NutriUon	
  and	
  Therapy.	
  	
  Winnipeg,	
  Canada,	
  1997.	
  
Invited	
  Speaker.	
  	
  "LepUn:	
  From	
  Rodents	
  to	
  Humans".	
  	
  InternaUonal	
  Diabetes	
  FederaUon	
  Congress,	
  Helsinki,	
  Finland,	
  
1997	
  
Invited	
   Speaker.	
   	
   “LepUn:	
   The	
   New	
   Lean	
   Gene”.	
   	
   European	
   Congress	
   of	
   Clinical	
   Chemistry	
   “Medlab97”,	
   Basel,	
  
Switzerland,	
  1997	
  
Invited	
  Speaker.	
   	
  Grand	
  Rounds.	
   	
  "LepUn:	
  From	
  Rodents	
  to	
  Humans".	
   	
  Tulane	
  University,	
  New	
  Orleans,	
  Louisiana,	
  
1997	
  
Invited	
   Speaker,	
   Plenary	
   Session.	
   	
   "Current	
   and	
   Future	
   ImplicaUons	
   For	
   the	
   Use	
   of	
   LepUn	
   in	
   the	
   Treatment	
   of	
  
Obesity".	
  	
  NAASO	
  Annual	
  MeeUng,	
  Cancun,	
  Mexico,	
  1997	
  
Invited	
  Speaker,	
  Conferencia	
  	
  “Diabetes,	
  obesity	
  y	
  lepUn”.	
  	
  Simposia	
  Harvard	
  -­‐	
  Joslin	
  -­‐	
  SBD,	
  XI	
  Congreso	
  Brasileño	
  de	
  
Diabetes,	
  Porto	
  Alegre,	
  Brazil	
  1997	
  
Medical	
  Grand	
  Rounds	
  -­‐	
  “The	
  Role	
  of	
  LepUn	
  in	
  Body	
  Weight	
  RegulaUon”.	
  	
  The	
  University	
  of	
  Texas.	
  San	
  Antonio,	
  TX,	
  
1997	
  
Research	
  Seminar:	
  “Strategies	
  for	
  the	
  treatment	
  of	
  type	
  II	
  diabetes”.	
  	
  Garvan	
  InsUtute.	
  Sydney,	
  Australia,	
  1997	
  
Research	
   Seminar:	
   “Recent	
   Advances	
   on	
   LepUn”.	
   	
   The	
   Walter	
   and	
   Eliza	
   Hall	
   InsUtute	
   for	
   Medical	
   Research.	
  	
  
Melbourne,	
  Australia,	
  1997	
  
Plenary	
  Lecturer:	
  “Strategies	
  for	
  the	
  treatment	
  of	
  Obesity”.	
   	
  NAASO	
  and	
  American	
  Society	
  of	
  Clinical	
  NutriUon.	
  	
  
Merida,	
  Mexico,	
  1997	
  
Congreso	
  Nacional	
  de	
  la	
  Sociedad	
  Española	
  de	
  Diabetes	
  y	
  Obesidad:	
  “LepUna	
  y	
  obesidad".	
  	
  Caceres,	
  Spain,	
  1997	
  
Invited	
   Speaker	
   -­‐	
   Bio-­‐chemistry	
   Seminar:	
   “Strategy	
   of	
   drug	
   discovery	
   for	
   the	
   treatment	
   of	
   obesity”.	
   	
   Indiana	
  
University	
  Medical	
  Center.	
  	
  Indianapolis,	
  IN,	
  1998	
  
Invited	
   Speaker:	
   American	
   Diabetes	
   AssociaUon	
   “LepUn	
   Pathway	
   as	
   a	
   Target	
   for	
   Treatment”.	
   	
   San	
   Francisco,	
  
California,	
  1998	
  
Invited	
  Speaker:	
  “Addressing	
  the	
  AcceleraUng	
  Cost	
  of	
  Chronic	
  Diseases:	
  	
  A	
  Case	
  Study”.	
  	
  MeeUng	
  the	
  21st	
  century	
  
healthcare	
  challenge:	
  	
  A	
  New	
  Vision	
  for	
  PharmaceuUcal	
  InnovaUon.	
  	
  PHRMA,	
  U.S.	
  Embassy.	
  Tokyo,	
  Japan,	
  1998	
  
Opening	
  Lecture	
  of	
  the	
  XIV	
  Sociedad	
  Española	
  de	
  Diabetes:	
  “En	
  el	
  camino	
  a	
  la	
  cura	
  de	
  la	
  Diabetes”	
  Murcia,	
  Spain,	
  
1998	
  
Keynote	
  lecture:	
  “A	
  new	
  endocrine	
  cell:	
  Biology	
  and	
  FuncUon	
  of	
  Adipocytes”	
  71st	
  Annual	
  MeeUng	
  of	
  the	
  Japan	
  
Endocrine	
  Society.	
  	
  Fukuoka,	
  Japan,	
  1998	
  
Plenary	
   lecture:	
   “LepUn:	
   the	
   Past,	
   Present	
   and	
   Future”.	
   	
   71st	
   Annual	
   MeeUng	
   of	
   the	
   Japan	
   Endocrine	
   Society.	
  	
  
Fukuoka,	
  Japan,	
  1998	
  
Plenary	
  lecture:	
  “From	
  New	
  Genes	
  to	
  New	
  Treatments”.	
  	
  Satellite	
  Symposium	
  of	
  the	
  8th	
  InternaUonal	
  Congress	
  on	
  
Obesity.	
  	
  Paris,	
  France,	
  1998	
  
Plenary	
  lecture:	
  “Emerging	
  Therapies	
  for	
  Type	
  II	
  Diabetes”.	
   	
  34th	
  Annual	
  MeeUng	
  of	
  the	
  European	
  AssociaUon	
  for	
  
the	
  Study	
  of	
  Diabetes.	
  	
  Barcelona,	
  Spain,	
  1998	
  
Conferencia	
  Magistral	
  -­‐	
  Hospital	
  Maciel:	
  “	
  LepUna	
  la	
  Voz	
  Del	
  Adiosito”.	
  Simposio	
  Obesidad	
  y	
  Diabetes	
  Mellitus	
  -­‐	
  
Cuando	
  Y	
  Como	
  Intervenir.	
  Montevideo,	
  Uruguay,	
  1998	
  
Conferencia	
   Magistral	
   -­‐	
   Hospital	
   Maciel:	
   “Intervenciones	
   Futuras	
   en	
   el	
   Manejo	
   de	
   la	
   Obesidad.	
   	
   Montevideo,	
  
Uruguay,	
  1998	
  
Lilly	
  Symposium	
  -­‐	
  Temas	
  actuales	
  en	
  Diabetes.	
  “LepUna	
  y	
  Obesidad”.	
  Montevideo,	
  Uruguay,	
  1998	
  
Invited	
   Speaker:	
   “Opciones	
   terapéuUcas	
   en	
   el	
   síndrome	
   de	
   insulinorresistencia”.	
   	
   XI	
   Congreso	
   ArgenUno	
   de	
  
Diabetes.	
  	
  Cordoba,	
  ArgenUna,	
  1998	
  
Invited	
  Speaker:	
  “LepUna	
  y	
  Obesidad”.	
  	
  XI	
  Congreso	
  ArgenUno	
  de	
  Diabetes.	
  	
  Cordoba,	
  ArgenUna,	
  1998	
  
Opening	
   Lecture:	
   “LepUna:	
   La	
   voz	
   del	
   Adiosito”.	
   	
   III	
   Curso	
   Sobre	
   InvesUgaciones	
   Biomedicas,	
   Universidad	
   de	
  
Granada	
  y	
  Consejo	
  Superior	
  de	
  InvesUgaciones	
  Cien~ficas.	
  	
  Granada,	
  Spain,	
  1998	
  
Symposium	
  Speaker:	
  	
  “New	
  Molecular	
  Target	
  for	
  the	
  treatment	
  of	
  Obesity”.	
  	
  “VI	
  MeeUng	
  on	
  Lipid	
  Metabolism	
  and	
  
Related	
  Pathology”	
  	
  InsUtuto	
  Superior	
  de	
  Ciencias	
  da	
  Sande-­‐Sul.	
  	
  Costa	
  da	
  Caprica,	
  Portugal,	
  1998	
  
Symposium	
  Chairman	
  and	
  Speaker:	
  	
  “Neuroendocrine	
  integraUon	
  of	
  appeUte".	
  	
  Experimental	
  Biology	
  ‘99	
  MeeUng.	
  	
  
Washington,	
  D.C.	
  1999	
  
Invited	
  Speaker:	
  "LepUn:	
  The	
  tale	
  of	
  an	
  obesity	
  gene	
  and	
  it's	
  applicaUon	
  to	
  children".	
   	
  Building	
  Bright	
  Futures:	
  
Neonatal,	
   Pediatric	
   and	
   Adolescent	
   NutriUon	
   in	
   the	
   21st	
   Century.	
   	
   Indiana	
   University	
   School	
   of	
   Medicine,	
  
Indianapolis,	
  IN.	
  	
  1999	
  
Symposium	
  Co-­‐Chairman	
  and	
  Speaker.	
  	
  "On	
  the	
  trail	
  to	
  cure	
  obesity".	
  	
  GeneUcs,	
  Pathophysiology	
  and	
  TherapeuUcs	
  
on	
  the	
  Eve	
  of	
  a	
  Major	
  Conceptual	
  RevoluUon.	
  	
  Euro-­‐Conference	
  InsUtute	
  Pasteur.	
  	
  Paris,	
  France,	
  1999	
  
Invited	
  Speaker:	
  "Insulin	
  Resistance:	
  A	
  target	
  for	
  drug	
  therapy	
  at	
  the	
  CMES	
  Ancillary	
  Symposium,	
  The	
  Endocrine	
  
Society.	
  	
  Toronto,	
  Canada,	
  2000	
  
VisiUng	
  Professor:	
   	
  “New	
  targets	
  for	
  the	
  treatment	
  of	
  obesity”.	
   	
  Medical	
  Grand	
  Rounds,	
  University	
  of	
  Piosburgh	
  
School	
  of	
  Medicine.	
  	
  Piosburgh,	
  PA.	
  	
  2001	
  
Invited	
  Speaker:	
   	
  “The	
  treatment	
  of	
  diabetes	
  in	
  the	
  new	
  Millennium.	
   	
  Italian	
  Society	
  of	
  Diabetes.	
   	
  Florence,	
  Italy,	
  
2002	
  
Symposium	
  Speaker:	
  	
  “New	
  Drug	
  Therapies	
  for	
  Obesity”	
  at	
  Obesity:	
  	
  Molecular	
  Causes	
  
and	
  New	
  Pathways	
  for	
  Treatment	
  and	
  PrevenUon.	
   	
  American	
  AssociaUon	
  for	
  the	
  Advancement	
  of	
  Science	
  (AAAS)	
  
Annual	
  MeeUng.	
  	
  Denver,	
  Colorado.	
  	
  2003	
  
Keynote	
  Speaker:	
   	
  “The	
  Do’s	
  and	
  Do	
  Not’s	
  in	
  Science:	
   	
  From	
  Fuller	
  Albright	
  to	
  the	
  Present”.	
  Graduate	
  Student	
  
Research	
  Day.	
  	
  East	
  Carolina	
  University.	
  Greenville,	
  NC.	
  	
  2003	
  
Symposium	
  Speaker:	
   	
  “Obesity	
  and	
  the	
  Metabolic	
  Syndrome:	
   	
  IdenUfying	
  Underlying	
  Mechanisms	
  and	
  Emerging	
  
Therapies	
  for	
  Pharmacological	
  Treatment”.	
  	
  PharmaceuUcal	
  EducaUon	
  Associates.	
  	
  Washington,	
  DC.	
  	
  2003.	
  
Roundtable	
  ParUcipant:	
   	
  “Obesity	
  and	
  Cancer”	
  NaUonal	
  Dialogue	
  on	
  Cancer.	
   	
  Sponsored	
  by	
  President	
  George	
  W.	
  
and	
  Barbara	
  Bush.	
  	
  Kennebunkport,	
  Maine.	
  	
  2003	
  
Keynote	
   Speaker	
   and	
   Chairperson:	
   	
   “OpportuniUes	
   and	
   Challenges	
   of	
   TherapeuUc	
   Development	
   for	
   Obesity”.	
  	
  
World	
  Obesity	
  Congress	
  &	
  Expo.	
  	
  Washington,	
  DC.	
  	
  2004	
  
Symposium	
   Speaker:	
   	
   “Addressing	
   the	
   Obesity	
   Epidemic:	
   	
   From	
   Bench	
   to	
   Bedside	
   to	
   Market”.	
   	
   The	
   Endocrine	
  
Society’s	
  86th	
  Annual	
  MeeUng.	
  	
  New	
  Orleans,	
  LA.	
  	
  2004	
  
Invited	
   Speaker:	
   	
   “Overcoming	
   Diabetes:	
   	
   A	
   Long	
   March	
   from	
   Discovery	
   to	
   CommercializaUon”.	
   	
   The	
   Opening	
  
Ceremony	
  of	
  the	
  Peking	
  University	
  Diabetes	
  Center.	
  	
  Beijing,	
  China.	
  	
  2004	
  
Invited	
  Speaker:	
  	
  “AnU-­‐Obesity	
  Drug	
  Development:	
  	
  From	
  Target	
  IdenUficaUon	
  to	
  Launch”.	
  	
  NAASO	
  2004	
  ScienUfic	
  
MeeUng.	
  	
  Las	
  Vegas,	
  NV.	
  	
  2004	
  
Invited	
  Speaker:	
   	
  “New	
  Therapies	
  for	
  Diabetes”.	
   	
  Leerink	
  Swann/MEDACorp.	
  Inaugural	
  Health	
  Care	
  Conference.	
  	
  
New	
  York,	
  NY.	
  	
  2005	
  
Invited	
  Speaker:	
  	
  “Insulin	
  SensiUvity	
  Enhancers	
  for	
  the	
  Treatment	
  and	
  PrevenUon	
  of	
  Diabetes“	
  Diabetes	
  and	
  Obesity	
  
Research	
  Day.	
  	
  East	
  Carolina	
  University,	
  Brody	
  School	
  of	
  Medicine.	
  	
  Greenville,	
  NC.	
  	
  2005	
  
Keynote	
  Speaker	
  and	
  Chairperson:	
  	
  “New	
  OpportuniUes	
  and	
  Challenges	
  of	
  TherapeuUc	
  Developments	
  with	
  Obesity	
  
and	
  Weight	
  Loss”.	
  	
  World	
  Obesity	
  Congress	
  &	
  Expo.	
  	
  Washington,	
  DC.	
  	
  2005	
  
Keynote	
  Speaker:	
   	
  “On	
  the	
  Trail	
  to	
  ARREST	
  the	
  Progression	
  of	
  Type	
  2	
  Diabetes”	
   	
  College	
  of	
  Agriculture	
  and	
  Life	
  
Sciences,	
  University	
  of	
  Arizona.	
  	
  Phoenix,	
  AZ.	
  	
  2005	
  
	
   	
  
Keynote	
  Speaker:	
  	
  “On	
  the	
  Trail	
  to	
  ARREST	
  the	
  Progression	
  of	
  the	
  Metabolic	
  Syndrome”	
  	
  8th	
  Symposium	
  Fundacion	
  
Lilly	
  “New	
  Approaches	
  to	
  the	
  Metabolic	
  Syndrome”	
  	
  San	
  Lorenzo	
  de	
  El	
  Escorial,	
  Madrid.	
  	
  2005	
  
Invited	
  Speaker:	
  “May	
  be	
  difficult	
  at	
  Umes…?”	
  At	
  The	
  5th	
  NaUonal	
  Metabolic	
  Day.	
  Utrecht	
  University,	
  	
  Amsterdam,	
  
The	
  Nederland	
  2006	
  
Keynote	
  Speaker:	
  “Diabesity”	
  13th	
  Annual	
  Kaiser	
  Permanente	
  Diabetes	
  Symposium.	
  Woodland	
  Hills,	
  CA	
  	
  2007	
  
	
  	
  
Invited	
  Speaker	
  	
  and	
  panel	
  member:	
  “Clinical	
  Trials,	
  Sewng	
  the	
  stage	
  for	
  the	
  future”.	
  At	
  the	
  inaugural	
  Clinical	
  Trial	
  
Regional	
  Exchange	
  Group,	
  The	
  North	
  Carolina	
  Biotechnology	
  Center.	
  Greenville	
  NC,	
  2007	
  
Post	
  Graduate	
  Course	
  in	
  Endocrinology:	
  “Obesity”.	
  At	
  the	
  Universidad	
  Catolica,	
  Montevideo,	
  Uruguay,	
  2008	
  
Invited	
  Speaker:	
  “Peers	
  for	
  Progress”.	
  At	
  the	
  School	
  of	
  Medicine,	
  Maciel	
  Hospital.	
  Montevideo,	
  Uruguay,	
  2008	
  
PUBLICATIONS	
  
1. Caro,	
  J.F.,	
  A.	
  Besarab,	
  J.R.	
  Burke,	
  and	
  J.A.	
  Glennon.	
  	
  Propranolol:	
  A	
  possible	
  role	
  in	
  the	
  treatment	
  of	
  renal	
  
osteodystrophy.	
  Lancet	
  II:451,1978.	
  
2. Caro,	
  J.F.,	
  and	
  A.	
  Besarab.	
  Propranolol	
  therapy	
  for	
  hyperparathyroidism.	
  Lancet	
  II:827,1978.	
  
3. Caro,	
  J.F.,	
  A.W.	
  Meikle,	
  J.H.	
  Check,	
  and	
  S.N.	
  Cohen.	
  "Normal	
  suppression"	
  to	
  dexamethasone	
  in	
  Cushing's	
  
disease:	
  An	
  expression	
  of	
  decreased	
  metabolic	
  clearance	
  for	
  dexamethasone.	
  J.	
  Clin.	
  Endocrinol.	
  Metab.	
  
47:667,1978.	
  
4. Ballas,	
   S.K.,	
   J.F.	
   Caro,	
   and	
   O.	
   Miguel.	
   Quinidine-­‐induced	
   hemolyUc	
   anemia:	
   Immunohematologic	
  
characterizaUon.	
  Transfusion	
  18:215,1978.	
  
5. Besarab,	
  A.,	
  and	
  J.F.	
  Caro.	
  Mechanism	
  of	
  hypercalcemia	
  in	
  malignancy.	
  Cancer	
  6:2276,1978.	
  
6. Caro,	
  J.F.,	
  A.	
  Besarab,	
  and	
  J.A.	
  Glennon.	
   	
  SymptomaUc	
  hypocalcemia	
  following	
  combined	
  calcitonin	
  and	
  
mithramycin	
  therapy	
  for	
  hypercalcemia	
  in	
  malignancy.	
  Cancer	
  Treat	
  Reports	
  62:1561,1978.	
  
7. Check,	
  J.H.,	
  J.F.	
  Caro,	
  L.	
  Jackson,	
  K.	
  Nowroozn	
  and	
  A.F.	
  Rakoff.	
  	
  Clinical	
  mixed	
  gonadal	
  dysgenesis	
  without	
  Y	
  
chromosome.	
  Am.	
  J.	
  Obstet.	
  Gynecol.	
  131:346,1978.	
  
8. Check,	
  J.H.,	
  J.F.	
  Caro,	
  and	
  J.T.	
  Flynn.	
  CysUc	
  gynecomasUa	
  in	
  a	
  male	
  treated	
  with	
  clomiphene	
  citrate.	
  Infert.	
  
Sterility	
  30:713,1978.	
  	
  
9. Caro,	
  J.F.,	
  A.	
  Besarab,	
  and	
  J.T.	
  Flynn.	
  Prostaglandin	
  E	
  and	
  hypercalcemia	
  in	
  breast	
  carcinoma:	
  Only	
  a	
  tumor	
  
marker?	
  A	
  need	
  for	
  prospecUve.	
  Am.	
  J.	
  Med.	
  66:337,1979.	
  
10. Caro,	
  J.F.,	
  H.L.	
  Israel,	
  and	
  J.A.	
  Glennon.	
  Galactorrhea	
  in	
  sarcoidosis:	
  Dynamic	
  studies	
  of	
  prolacUn,	
  growth	
  
and	
  gonadotropic	
  hormone	
  levels.	
  Am.	
  J.	
  Med.	
  Sci.	
  277:1,1979.	
  
11. Check,	
  J.H.,	
  J.F.	
  Caro,	
  B.	
  Kendall,	
  L.A.	
  Peris,	
  and	
  B.L.	
  Wellenback.	
  Cushing's	
  syndrome	
  in	
  pregnancy:	
  Effect	
  of	
  
associated	
  diabetes	
  on	
  fetal	
  and	
  neonatal	
  complicaUons.	
  Am.	
  J.	
  Obstet.	
  Gynecol.	
  44:846,1979.	
  
12. Check,	
  J.H.,	
  J.F.	
  Caro,	
  L.	
  Criden,	
  R.	
  Meltz,	
  and	
  K.	
  Brownstein.	
  Leyding	
  cell	
  responsiveness	
  with	
  gonadal	
  cell	
  
resistance	
  to	
  gonadotropin	
  therapy	
  in	
  Kallman's	
  syndrome.	
  Am.	
  J.	
  Med.	
  67:495,1979.	
  
13. Caro,	
   J.F.,	
   J.H.	
   Castro,	
   and	
   J.A.	
   Glennon.	
   Effect	
   of	
   long-­‐term	
   propranolol	
   administraUon	
   on	
   parathyroid	
  
hormone	
  and	
  calcium	
  concentraUon	
  in	
  primary	
  hyperparathyroidism.	
  Ann.	
  Int.	
  Med.	
  91:740,1979.	
  
14. Caro,	
   J.F.,	
   N.G.	
   Sloane,	
   and	
   J.A.	
   Glennon.	
   Hyperthyroidism	
   with	
   normal	
   serum	
   T4,	
   T3	
   and	
   TBG	
  
immunoreacUvity.	
  J.	
  Clin.	
  Pat.	
  33:868,1980.	
  
15. Caro,	
  J.F.,	
  and	
  P.D.	
  Woolf.	
  Pituitary-­‐ovarian	
  axis	
  responsiUvity	
  to	
  prolonged	
  GnRH	
  infusion	
  in	
  normal	
  and	
  
hyperprolacUnemic	
  women.	
  J.	
  Clin.	
  Endo.	
  Metab.	
  50:999,1980.	
  
16. Insogna,	
   K.L.,	
   D.R.	
   Bordley,	
   J.F.	
   Caro,	
   and	
   D.H.	
   Lockwood.	
   Osteomalacia	
   and	
   weakness	
   due	
   to	
   excessive	
  
antacid	
  ingesUon.	
  J.A.M.A.	
  244:2544,1980.	
  
17. Castro,	
  J.H.,	
  J.F.	
  Caro,	
  Kim,	
  and	
  J.A.	
  Glennon.	
  Effects	
  of	
  PTH	
  infusion	
  in	
  primary	
  hyperparathyroidism	
  on	
  
plasma	
  prolacUn	
  in	
  man.	
  J.	
  Clin.	
  Endo.	
  Metab.	
  51:397,1980.	
  
18. Caro,	
  J.F.,	
  and	
  J.M.	
  Amatruda.	
  FuncUonal	
  relaUonship	
  between	
  insulin	
  binding,	
  acUon	
  and	
  degradaUon.	
  J.	
  
Biol.	
  Chem.	
  255:10052,1980.	
  
19. Caro,	
   J.F.,	
   and	
   J.M.	
   Amatruda.	
   Insulin	
   receptors	
   in	
   hepatocytes:	
   Post	
   receptor	
   events	
   mediate	
   down	
  
regulaUon.	
  Science	
  210:1029,1980.	
  
20. Caro,	
  J.F.,	
  and	
  J.M.	
  Amatruda.	
  	
  The	
  effects	
  of	
  fasUng	
  on	
  glucagon	
  binding	
  and	
  acUon	
  in	
  isolated	
  hepatocytes.	
  
Metabolism	
  29:732,1980.	
  
21. Caro,	
  J.F.	
  and	
  J.A.	
  Glennon,	
  and	
  H.L.	
  Israel.	
  	
  	
  Neuroendocrine	
  studies	
  in	
  sarcoidosis.	
  	
  William,	
  J.W.	
  and	
  Davis,	
  
B.	
  H.	
  (Eds.),	
  Alpha	
  Omega	
  Publ.	
  pp.587,1980.	
  
22. Cech,	
  J.N.,	
  R.B.	
  Freeman,	
  J.F.	
  Caro,	
  and	
  J.M.	
  Amatruda.	
  Insulin	
  acUon	
  and	
  binding	
  in	
  isolated	
  hepatocytes	
  
from	
  fasted,	
  streptozotocin	
  diabeUc	
  and	
  older,	
  spontaneously	
  obese	
  rats.	
  Biochem.	
  J.	
  188:839,1980.	
  
23. Caro,	
  J.F.,	
  and	
  J.M.	
  Amatruda.	
  Evidence	
  for	
  the	
  modulaUon	
  of	
  insulin	
  acUon	
  and	
  degradaUon	
  independently	
  
of	
  insulin	
  binding.	
  Am.	
  J.	
  Physiol.	
  240:E325,1981.	
  
24. Besarab,	
  A.,	
  J.F.	
  Caro,	
  B.U.	
  Ihle,	
  J.F.	
  Burke,	
  and	
  J.A.	
  Glennon.	
  Suppression	
  of	
  secondary	
  hyperparathyroidism	
  
by	
  propranolol	
  in	
  renal	
  failure	
  paUent.	
  Nephron	
  27:127,1981.	
  	
  
25. Besarab,	
  A.	
  and	
   	
  J.F.	
  Caro.	
   	
  Increased	
  absolute	
  calcium	
  binding	
  to	
  albumin	
  in	
  hypoalbuminaemia.	
   	
  J.	
  Clin.	
  
Path.	
  34:1368,1981.	
  
26. Basal,	
  S.,	
  P.D.	
  Woolf,	
  J.A.	
  Fischer,	
  and	
  J.F.	
  Caro.	
  Dopamine	
  does	
  not	
  affect	
  parathyroid	
  funcUon	
  in	
  man.	
  J.	
  
Clin.	
  Endo	
  Metab.	
  54:651,1982.	
  
27. Caro,	
  J.F.,	
  and	
  J.M.	
  Amatruda.	
  The	
  regulaUon	
  of	
  lipid	
  synthesis	
  in	
  freshly	
  isolated	
  hepatocytes	
  and	
  primary	
  
cultures	
  of	
  hepatocytes	
  from	
  fasted	
  rats:	
  The	
  primary	
  role	
  of	
  insulin.	
  Metabolism	
  31:14,1982.	
  
28. Caro,	
  J.F.,	
  and	
  J.M.	
  Amatruda.	
  GlucocorUcoid-­‐induced	
  insulin	
  resistance:	
  The	
  importance	
  of	
  post	
  receptor	
  
events	
  in	
  the	
  regulaUon	
  of	
  insulin	
  binding	
  and	
  degradaUon.	
  J.	
  Clin.	
  Invest.	
  69:866,1982.	
  	
  
29. Caro,	
  J.F.,	
  G.	
  Muller	
  and	
  J.A.	
  Glennon.	
  Insulin	
  processing	
  by	
  the	
  liver.	
  J.	
  Biol.	
  Chem.	
  257:8459,1982.	
  
30. Kauffman,	
  J.M.,	
  and	
  J.F.	
  Caro.	
  Insulin	
  resistance	
  in	
  uremia:	
  CharacterizaUon	
  of	
  insulin	
  acUon	
  binding	
  and	
  
processing	
  in	
  isolated	
  hepatocytes	
  from	
  chronic	
  uremic	
  rat.	
  J.	
  Clin.	
  Invest.	
  71:698,1983.	
  
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine
Jose F. Caro - Art and Medicine

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INterCHANGE Bios and Workshop Descriptions .compressed
 

Jose F. Caro - Art and Medicine

  • 1. Curriculum Vitae     Jose  F.  Caro,  M.D.   Artist Dis/nguished  Professor  of  Medicine  Emeritus   General  Informa/on   Home  Address:                      5947  McKinges  Circle                                                                                      Carmel,  IN  4603   Telephone:                                              252-­‐414-­‐1738   Email:                                                                jfcaro13@gmail.com   webs:                                                                  www.josefcaro.com                                                                                        www.linkedin.com/in/josefcaro   Birthplace:                        Granada,  Spain;  June  27,  1948   CiUzenship:                      USA   Marital  Status:                        Married  with  Marice  E.  Caro  for  42  years   Children:                      Maricelina,  Rodolfo,  Marina  and  Rafael   Grand  Children:                      Olivia,  Elise,  Bridget,  Julia  and  Julian   Summary   Jose F. Caro began a new career in art in 2008. He went back to college to pursue a degree in fine art and is having his pastel paintings peer reviewed by his colleagues. Before this transformation he was the Vice President of Endocrine Research and Clinical Investigation and Global Diabetes Care at Eli Lilly & Comp for 12 years. Prior to joining Lilly he was the Magee Professor of Medicine and Chairman of the Department at Jefferson Medical College for 5 years and the Chief of Endocrinology and Director of the University Diabetes Center at East Carolina University for 10 years. Dr. Caro received his M.D. degree with honors in 1973 from the School of Medicine in Madrid, Spain and Montevideo, Uruguay. He completed residency and fellowship training at Jefferson Medical College and at the University of Rochester. He is Board Certified in Internal Medicine and Endocrinology and Metabolism. Dr. Caro was a member of various professional and honorary societies, including the American Society for Clinical Investigation (Young Turk) and the Association of American Physicians (Old Turk). He was the recipient of the Medal of Honor and is an honorary member of the Real Academy of Medicine of Granada, Spain. He is the Honorary Director of the Peking Diabetes Center and Honorary Professor of the Peking University Health Science Center in China.Dr. He has authored about 200 papers, book chapters and books and he was recently listed as the third most highly cited investigator in the world in the field of Obesity Research by ISI. He served as Editor and Editorial Board member of several journals and has lectured around the world. Dr. Caro has served as a member and Chairman of several study sections at the NIH and more recently as a member of the NIDDK Advisory Council to the President. He lives in Carmel IN with Marice, his spouse for 42 years. His main artistic inspiration is his family...his four children and five grandchildren.
  • 2. ________________________ART_______________________________   Why  a  Second  Career  in  Art?   My great granduncle, Rafael Eiroa, was an artist in the late XIX century Spain. One of his paintings was in my parents’ home. It was a middle age woman sitting in a dilapidated straw chair. Her eyes were unfixed and gazed into space. It was almost as if she was waiting to catch the opportunity she did not have.  Every night I fell to sleep thinking about her, about opportunities, the future, and most definitively that I wanted to paint like my uncle Rafael.  After the Spanish Civil war, my family like many others immigrated to Argentina looking for the freedom they did not have. I still remember vividly those 21 days crossing the ocean aboard the steamship Buena Esperanza (Good Hope).  My great granduncle’s large canvas was carefully removed from the frame by my father, rolled and stored into a trunk labeled “memories from Spain”. Many years had passed before my mother decided to open the trunk.  The canvas was severely damaged.  I was a teenager and had forgotten the woman sitting in a chair. Nevertheless, my parents knowing my interest for art suggested that I repair her. I bought oils and brushes and I did it! I knew then what I wanted to become. But when I told my father about my desire to enter the school of art he said “study son, you will always have time to paint”.  I became a physician and soon after graduation I moved to the USA with my wife and daughter looking for freedom and opportunities, like my parents did. It has been a great 40 years journey but I never found time to paint like my father said. Thus, I left medicine and science at age 60 to find time to paint. My youngest son Rafael after reading this statement he smiled and firmly said “I will start a career in art this fall semester”. If I finish wanting to paint like my uncle Rafael and my son Rafael, I would say it is not a bad way to end. Presentations at Juried Shows.- 2009 Greenville Museum of Art Annual Juried Show. Greenville, NC “Only in California” and “The Magic Five Minutes in the Morning” 2011 Pastel Society of North Carolina, Winter Exhibition. Greensboro, NC “The Beach at Acadia National Park” 2013 Ninth Annual Northeast National Pastel Exhibition, Old Forge, NY “I am not a little girl anymore” 2013 27th Annual International Exhibit. Northwest Pastel Society. Tacoma, WA “At Acadia National Park” 2013 First Carteret County Juried Art Show. Emerald Isle, NC “Shall I grow up?” and “At the Poconos Mountains”
  • 3. 2013 North Carolina Statewide Juried Pastel Exhibition. On Common Grounds: Pastel Paintings From The Mountains To The Sea. “I am not a little girl anymore” 2013 The 23rd International Association of Pastel Societies Juried Exhibition. Marshfield, MA “I am not a little girl anymore” 2014 The Southeastern Pastel Society’s 16th International Exhibition. Oglethorpe University Museum of Art. Atlanta, GA “I am Not Alone” and “Dreaming About Spring” 2014 28th Annual International Exhibit. Northwest Pastel Society. Tacoma, WA “At Acadia National Park” 2014 Northeast National Pastel Exhibition, View.Old Forge NY “Maternity” 2014 Degas Pastel Society Fifteenth Biennial National Exhibition. New Orleans, LA. “Maternity” and “I am not alone” 2014 Southeastern Pastel Society On-Line Juried Exhibition. “Choices” 2015 Pastel Society of the West Coast 2015 Annual Members Show. Haggis Museum, Stockton, CA. “I am not alone” 2015 Southeastern 2015 juried members exhibition. Quinlan Visual Art
 Center, Gainesville, GA. “Maternity” 2015 Degas Pastel Society Nineteenth Membership Exhibition. New Orleans, LA “Choices” and “I am not a little girl anymore” 2015 The Peninsula Art League 2015 Open Juried Show. Harbor History Museum, Gig Harbor, WA “Maternity” and “The hug” One Person Shows.- 2013 Emerald Isle Recreation Center, Emerald Isle, NC
  • 4. 2013 Bogue Banks Public Library, Pine Knoll Shores, NC 2013 Arts for the Hospital, Carteret Hospital, Morehead City, NC Presentations at Non Juried Shows.- 2013 Art for the Heart Annual Exhibition. Carteret County Art Council. Morehead City, NC . “I am not a little girl any more” and “The beach at Emerald Isle” Awards/Honors/Publications.- 2012 The Editor Choice: “Celebration of Water”. Art & Beyond Vol. 6, page 16, 2012. 2013 Juried Associate Member of the Pastel Society of America (PSA) 2013 Featured Artist of the Week with “Are we ready to leave home” at Artists Registry.com 2013 Featured Artwork @The Library. The Shoreline, Vol. 9, No. 8, p. 10 2013 Featured Pastel Artist. News-Time, Vol. 102, No.59, p. 2013 News and Mentions. Art Line, Pastel Society of NC. Vol. 2013 May 2014 The Artist’s Magazine. Annual Art Competition. Portrait/Figure Third Place Winer “I am not a little girl anymore” 2015 Juried Full Member of the Degas Pastel Society. 2015 Juried Full Member Indiana Artists Club Professional Societies and Memberships.- 2008 - 2012 The Indiana Art Association 2009 - Present Hoosier Salon, Patron Association and Fine Art Gallery 2009 - 2012 Northern Indiana Pastel Society 2012 - 2014 Craven Arts Council & Gallery, Inc., NC
  • 5. 2012 - 2014 Seaside Arts Council, NC 2012 - 2014 Art Council of Carteret County, NC 2012- 2014 Pastel Society of North Carolina 2012- 2014 Greenville Museum of Art, NC 2013- Present Juried Associate Member Pastel Society of America (PSA) 2013- Present Northwest Pastel Society 2014- Present Southeastern Pastel Society 2014 - Present Juried member of the Degas Pastel Society Invited Lectures. - “The role of art in society”. Lookout Rotary Club, Morehead City, NC 2012 “The Past and Present of Pastel Painting”. At the Art for the Hospital Annual Meeting. Carteret Community Hospital, Morehead City, NC 2013 Consultant/Advisory Activities. - Member of the Board of Arts for the Hospital. Carteret County Community Hospital, Morehead City, NC Member of the Jury for Arts for the Heart, Student Category, Carteret County Art Council, Morehead City, NC Art education.- 2008-2010 Semester Courses in Fine Art at the Indianapolis Art Center. 2010-2012 Study Fine Art at CCC College, Morehead City, NC 2011-Present Participation at Workshops, critic sections and art classes with experience artists such us W. Creevy, R. McKinley, P. Newell.
  • 6. _______________________MEDICINE_____________________   MEDICAL  EDUCATION   1967  -­‐  1973     School  of  Medicine,  Universidad  Autonoma  de  Madrid,  Spain  and  School  of  Medicine,   Universidad  de  la  Republica,  Montevideo,  Uruguay     POSTGRADUATE  TRAINING   1974  -­‐  1977     Residency   in   Internal   Medicine,   Thomas   Jefferson   University   Hospital   of   Thomas   Jefferson  University,  Philadelphia,  Pennsylvania   1977  -­‐  1978     Fellowship   in   Internal   Medicine,   Thomas   Jefferson   University   Hospital   of   Thomas   Jefferson  University,  Philadelphia,  Pennsylvania   1978  -­‐  1981     Fellowship   in   Endocrinology   and   Metabolism,   Strong   Memorial   Hospital,   University   of   Rochester  School  of  Medicine  and  DenUstry,  Rochester,  New  York   CERTIFICATIONS   1979       Board  CerUficaUon  in  Internal  Medicine,  American  Board  of  Internal  Medicine   1984       Board   CerUficaUon   in   Endocrinology   and   Metabolism,   American   Board   of   Internal   Medicine   APPOINTMENTS   1981  -­‐  1983     Assistant   Professor   of   Medicine,   Endocrinology   and   Metabolism,   Jefferson   Medical   College  of  Thomas  Jefferson  University,  Philadelphia,  Pennsylvania   1983  -­‐  1986     Associate  Professor  of  Medicine,  SecUon  Head  of  Endocrinology  and  Metabolism,  East   Carolina  University  School  of  Medicine,  Greenville,  North  Carolina   1986  -­‐  1991     Professor  of  Medicine,  SecUon  Head  of  Endocrinology  and  Metabolism  and  Director  of   the  University  Diabetes  Center,  East  Carolina  University  School  of  Medicine,  Greenville,   North  Carolina                                                                                                                                      The  Division  of  Endocrinology  and  Metabolism  was  founded.  Six  faculUes  were  recruited   and  mentored  and  all  became  funded  by  the  NIH.  A  comprehensive  Fellowship  Program  
  • 7. was   approved.   The   ECU   Diabetes   and   Obesity   Center   was   established.   Dr.   J.   F.   Caro   became  Program  Director  of  the  “ECU  Diabetes  Program  Project”,  the  largest  NIH  award   in   the   history   of   the   University.   Basic   research   discoveries   were   made   such   as   mechanism(s)  of  IRTK  defects  in  liver,  muscle  and  liver  from  humans  with  diabetes  and   clinical  research  observaUons  were  made  such  as  that  the  gastric  bypass  surgery  prevent   diabetes  by  40  folds  in  people  with  pre-­‐diabetes  and  reverse  diabetes  in  more  than  80   percent  of  paUents  for  more  than  10  years.   1991  -­‐  1996     Magee   Professor   of   Medicine   and   Chairman   of   the   Department,   Jefferson   Medical   College  of  Thomas  Jefferson  University,  Philadelphia,  Pennsylvania                                                                                                  The  Department  of  Medicine  tripled  its  NIH  funding  and  moved  from  the  middle  third  to   the  upper  third  of  NIH  ranking.  The  residency  program  became  the  largest  in  the  State   with  most  house  staff  elecUng  a  career  on  primary  care.  Out  paUent  encounters  tripled   and  hospital’s  paUent  duraUon  of  hospitalizaUon  decreased  by  half.  The  budget  of  the   Department   conUnued   generaUng   overage   for   program   development.   All   this   was   achieved   without   a   significant   increase   in   FTEs.   This   is   what   our   Dean   called   “producUvity  without  expansion”   1996  -­‐  2008     Vice   President,   Endocrine   Research   and   Clinical   InvesUgaUon   and   Vice   President   of   Global  Diabetes  Care.  Lilly  Research  Laboratories,  Eli  Lilly  &  Comp,  Lilly  Corporate  Center,   Indianapolis,  IN                                                                                                The  focus  was  on  drug  discovery  from  hypothesis  generaUon  in  the  laboratory  to  prove   of  concept  in  phase  2  clinical  trials.  The  effort  involved  a  heavily  matrix  organizaUon  with   chemistry,   toxicology,   ADME,   biology,   clinical   pharmacology,   markeUng,   business,   etc.   More  than  40  compounds  were  discovered  that  fulfilled  all  FDA  requirements  to  enter   clinical  trials.  The  endocrine  porlolio  transformed  from  only  Insulin  to  a  more  complete   porlolio   with   several   INDs   and   NDAs   sUll   in   clinical   trials   from   this   decade’s   drug   discovery  pipeline.   1996  -­‐  2008     Professor  of  Medicine,  Indiana  University  School  of  Medicine         Indianapolis,  IN   2005  -­‐  Present     DisUnguished   Professor   of   Medicine,   Emeritus,   East   Carolina   University   School   of   Medicine,  Greenville,  NC   2007  –  Present     Co-­‐Founder,   Chief   ScienUfic   Officer   Emeritus   and   Honorary   Member   of   the   ExecuUve   Commioee  of  Peers  for  Progress.  AAFP,  University  of  North  Carolina,  Chapel  Hill,  NC   2012-­‐Present                                                President  and  Founder,  JFC  SoluUons  LLC   AWARDS  AND  RESEARCH  GRANTS  (direct  cost  only)   1979  -­‐  1981     Juvenile  Diabetes  FoundaUon  Fellowship  Award  (P.I.)  
  • 8.       ($75,000)   1981  -­‐  1983     American  Diabetes  AssociaUon  Wayne  Newton  Research  Grant  (P.I.)         ($68,750)   1981  -­‐  1982     Small  Grant  Award  PHS  Biomedical  Research  Support  Grant  5    S07RR0514,  Jefferson            Jefferson  Medical  College  (P.I.)                                                                                                    ($120,000)   1981  -­‐  1982     Department  of  Medicine  Research  Grant,  Jefferson  Medical     College  (P.I.)         ($12,500)   1981  -­‐  1983     Juvenile  Diabetes  FoundaUon  Research  Grant  (P.I.)         ($110,000)   1982  -­‐  1983     Research  Grant,  Upjohn  Company  (P.I.)         ($31,250)   1982  -­‐  1985   New  InvesUgator  Research  Award  1  R23AM  30558,  NaUonal  InsUtutes  of  Health  (PI)         ($176,500)   1984  -­‐  1985     Research  Grant,  5-­‐81011  Years  Laboratories  (P.I.)         ($43,750)   1985  -­‐  1987     Research  Grant,  Upjohn  Company  (P.I.)         ($50,000)   1985  -­‐  1988     Research  Grant,  R01-­‐AM  32585  NaUonal  InsUtutes  of  Health  (P.I.)         ($297,000)   1986  -­‐  1990   Research  Grant,  R01-­‐DK  38066  NaUonal  InsUtutes  of  Health  (P.I.)  (This  grant  was  funded   but  was  inacUvated  because  of  overlap  with  the  Program  Project  DK  36296   1987  -­‐  1988     Sponsor   of   Fogerty   Fellowship   Award   from   the   NaUonal   InsUtutes   of   Health   (IF05TW04048)  to  Dr.  Ivan  Contreras   1987  -­‐  1992     ECU   Diabetes   Program   Project,   P01-­‐DK   36296   NaUonal   InsUtutes   of   Health   (Program   Director)         ($2,550,000)   1987  -­‐  1992     Research  Grant,  Eli  Lilly  Company  (P.I.)         ($375,000)   1988  -­‐  1989     Research  Grant,  Glaxo  PharmaceuUcal  Company  (P.I.)           ($62,500)   1988  -­‐  1989     Research  Grant,  R03-­‐DK  41191-­‐1  NaUonal  InsUtutes  of  Health  (P.I.)         ($41,250)   1988  -­‐  1989     Research  Grant,  Pfizer  PharmaceuUcal  Company  (P.I.)         ($30,000)  
  • 9. 1989  -­‐  1992   Sponsor  of  Fellowship  Award  from  the  NaUonal  InsUtutes  of  Health  (IF32DK08477)  to  Dr.   Jacob  Friedman   1990  -­‐  1991     Research  Grant,  Park  Davis  PharmaceuUcal  Company  (P.I.)         1990   Small  Grant  Award:  Roaring  VisiUng  Professorship  Program  in  Diabetes  Management         ($6,250)   1990       Research  Grant,  1R03-­‐DK  2924  NaUonal  InsUtutes  of  Health  (P.I.)         ($41,250)   1990  -­‐  1992     Research  Grant,  Amylin  PharmaceuUcal  Company  (P.I.)  ($100,000)   1991  -­‐  1993     Sponsor   of   Fellowship   Award   to   Dr.   Bartolome   Burguera   from   the   Juvenile   Diabetes   FoundaUon   1991  -­‐  1992     Research  Grant,  Hoechst-­‐Roussel  PharmaceuUcals,  Inc.  (P.I.)         ($62,500)   1992  -­‐  1994     Sponsor  of  Fellowship  Award  to  Dr.  Robert  Considine  from  the                                                                                                                                        NaUonal  InsUtutes  of  Health  (IF32DK08888)   1993  -­‐  1994     Research  Grant,  Eli  Lilly  Company  (P.I.)         ($96,015)   1993  -­‐  1994     Research  Grant,  Eli  Lilly  Company    (Co-­‐PI)         ($65,235)   1993  -­‐  1995     Research  Grant,  Amylin  PharmaceuUcal,  Inc.  (P.I.)         ($37,676)   1994  -­‐  1995     Research  Grant,  Miles  Laboratories  (P.I.)         ($153,125)   1994  -­‐  1995     Research  Grant,  Pfizer  PharmaceuUcals  (Co-­‐Invest.)         ($37,500)   1994  -­‐  1996     Research  Grant,  CI-­‐991,  Park  Davis  PharmaceuUcals  (Co-­‐Invest.)         ($47,000)   1992  -­‐  1997     Research  Grant,  R01-­‐DK  44950  NaUonal  InsUtutes  of  Health  (P.I)                                                                                                ($1,900,000)       1994  -­‐  2002     Research  Grant,  UO1-­‐DK48468,  NaUonal  InsUtutes  of  Health  (P.I.)                                                                                                  ($3,422,165)  
  • 10. SPECIAL  RESEARCH  GRANTS   2006-­‐2012                                                Bringing  Research  In  Diabetes  Through  Environment  and  Systems    (BRIDGES).  See      Press   Release   Cape   Town,   South   Africa,   5   December   2006   BRIDGES@IDF.org   Dr.   Caro   idenUfied  the  need  of  translaUonal  research  in  diabetes  at  the  global  level.  He  wrote  a   Grant   to   the   Lilly   FoundaUon   and   provided   support   to   the   InternaUonal   Diabetes   FederaUon.                                                                                                  ($10,000,000)   2007-­‐2012                                      Peers  for  Progress.  See  Press  Release  Leak  wood,  KS,  USA,  June  20,  2007,www.lilly.com/ product/acceess/foundaUon,  Peersforprogress.org                                                                                                Dr.  Caro  idenUfied  the  need  of  new  methods  for  paUent  educaUon  in  diabetes.  He  wrote   a  Grant  to  the  Lilly  FoundaUon  and  provided  support  to  the  American  Academy  of  Family   Physicians  FoundaUon.  Peers  for  progress  will  idenUfy  and  train  laid  volunteers  who  have   diabetes  and  empower  them  to  assist  other  people  with  diabetes.  The  goal  is  to  educate   one  percent  of  the  people  with  diabetes  or  two  million  diabetes  to  become  mentors   around   the   world.   The   concept   was   validated   at   a   World   Health   OrganizaUon   consultaUon,  5-­‐7  November  2007  in  Geneva.                                                                                                ($15,000,000)   HONORS  AND  NAMED  LECTURESHIPS   1986-­‐1992     Recipient   of   the   “   Pearl   Lecturer”   every   year   while   in   the   Faculty   (Senior   Medical   Students'  Teaching  Award).  East  Carolina  University  School  of  Medicine,  Greenville,  NC   1988  -­‐2012     Member  of  the  American  Society  of  Clinical  InvesUgators  (Young  Turk)   1991       Outstanding   InvesUgator   Award.   Department   of   Medicine   Fish   Annual   Research   Day,   East  Carolina  University  School  of  Medicine,  Greenville,  NC,  1991.   1992       Karl   Paschkis   Lecturer,   "NIDDM:   Lessons   from   the   Laboratory."     The   Philadelphia   Endocrine  Society,  Philadelphia,  Pennsylvania,  1992.   1993       Bernardo   A.   Houssay   Lecturer,   "Insulin   Resistance   in   Type   II   Diabetes",   InternaUonal   Diabetes  FoundaUon  and  The  Costa  Rican  AssociaUon  of  Endocrinology,  San  Jose,  Costa   Rica,  1993.   1996       Mithoffer  Lecturer,  "LepUn:    The  Tale  of  an  Obesity  Gene",  Medical  University  of  South   Carolina,  Charleston,  SC,  1996.     1996       Alexander  Marble  Lecturer,  “Obesity:  A  syndrome  of  LepUn  Resistance”.  Joslin  Diabetes   Center.    Harvard  Medical  School.  Boston,  Massachuseos,  1996.   1997       BanUng  and  Best  Lecturer:  “Discovery  of  LepUn”.  University  of  Toronto.    Canada  Diabetes   AssociaUon.    Toronto,  Canada,  1997   1998       Eugene  Furth  Lecturer  “On  the  trail  to  cure  Diabetes”    East  Carolina  University  School  of   Medicine,  Greenville,  North  Carolina,    1998  
  • 11. 1998       A.M.   Cohen   Memorial   Lecturer:   “On   the   Trail   to   Cure   Diabetes”.     VII   InternaUonal   Symposium   on   Insulin   Receptors   and   Insulin   AcUon:   Molecular   and   Clinical   Aspects.     Jerusalem,  Israel,    1998   1998       Recipient   of   the   Medal   of   Honor   and   Honorary   Membership   to   the   Real   Academy   of   Medicine  of  Granada.    Granada,  Spain,  1998   1991  -­‐  2001     The  third  most  highly  cited  invesUgators  in  the  field  of  Obesity  Research  by  the  InsUtute   for  ScienUfic  InformaUon  (I.S.I).   2000  -­‐  2012     Member  of  the  AssociaUon  of  American  Physicians  (Old  Turk)   2004  -­‐  present     Honorary  Director  of  the  Peking  Diabetes  Center  and  Honorary  Professor  of  the  Peking   University  Health  Science  Center.    Peking,  China.   2005       The   Leslie   Nicholas   Lecture   “The   scienUfic   Basis   of   New   Therapies   for   Obesity”.   The   College  of  Physicians  of  Philadelphia,  PA         EDITORIAL  ACTIVITIES   1988  -­‐  1996     Associate  Editor,  Advances  in  Diabetologia   1991  -­‐  1997     Associate  Editor,  Diabetes  Care   1991  -­‐  2002     Editorial  Board,  Journal  of  Clinical  Endocrinology  and  Metabolism   1992  -­‐  2002     SecUon  Editor,  Obesity  Research,  North  American  AssociaUon  for  the  Study  of  Obesity   1994  -­‐  1999       Associate  Editor,  Medicina  y  Cultura   1985  -­‐  2008     Associate  Editor,  Metabolism  Clinical  and  Experimental   2001  -­‐2005     SecUon  Editor,  NutriUon  and  Obesity,  Endotext.com   2004  -­‐  2006     Co-­‐Editor,  The  Metabolic  Syndrome  at  the  Beginning  of  the  XXI  Century:    A  GeneUc  and   Molecular  Approach       2005  -­‐  2008                          Editorial  Board,  Journal  of  Clinical  Endocrinology  and  Metabolism   2005  –  2008     InternaUonal  Editorial  Board,  Obesity  and  Metabolism   CONSULTANT  ACTIVITIES  TO  NIH   1985  -­‐  1989     Member,  Metabolism  Study  SecUon,  NaUonal  InsUtutes  of  ArthriUs,  Diabetes  and  Kidney   Diseases.    NaUonal  InsUtutes  of  Health   1989       Special  Reviewer,  Study  SecUon  for  Small  Business  InnovaUon  Research,  Pharmacology   Panel,  NaUonal  InsUtutes  of  Health  
  • 12. 1989       Member,   Site   Visit   Team,   General   Clinical   Research   Center   Commioee.     NaUonal   InsUtutes  of  Health   1989       Member,  Site  Visit  Team  to  review  a  NIH  General  Clinical  Research  Center   1990       Member,  Clinical  Sciences  Study  SecUon  Site  Visit.    NaUonal  InsUtutes  of  Health   1991       Member,  NIH  Site  Visit  Team,  General  Clinical  Research  Center   1992       Member,  Special  Review  Commioee,  NaUonal  InsUtute  of  General  Medical  Sciences,  NIH   1992       Member,   External   Advisory   Commioee,   Sims'   Obesity   and   NutriUon   Research   Center,   NIDDK  and  NICHD   1992       Member,  NIDDK  Special  Grant  Review  Commioee   1992       Chairman,   Diabetes   Endocrinology   Research   Center   Study   SecUon,   NIH,   Bethesda,   Maryland   1992       Member,  Site  Visit  Team,  General  Clinical  Research  Center,  NaUonal  InsUtute  of  Health   1993       Chairman,   Ad   Hoc   Review   Group   SSS-­‐L   Clinical   Sciences   Review   SecUon,   NaUonal   InsUtute  of  Health.   1994       Member,  Behavioral  and  Neurosciences  Special  Emphasis  Panel,  NIH   1995       Member,  Ad  Hoc  Review  Commioee,  Diabetes  Research  and  Training  Centers,  NaUonal   InsUtute  of  Health   1998                                    Member,  Congressionally  Mandated  Diabetes  Research  Working  Group  and  Chairman  of   the  Industry/Academia  Subgroup,  NaUonal  InsUtute  of  Health  (NIH).   1996  -­‐  2000     Member,   Subcommioee   B   of   the   Diabetes   and   DigesUve   and   Kidney   Diseases   Special   Grants   Review   Commioee,   NaUonal   InsUtute   of   Diabetes   and   DigesUve   and   Kidney   Diseases  (NIDDK),  NIH         2000  -­‐  2004     Member   of   the   NaUonal   InsUtute   of   DigesUves   and   Diabetes   and   Kidney   Diseases   Advisory   Council,   NIH   and   Chairman   of   the   Concurrence   Grant   Awards   Approval   Commioee  of  the  NIDDK  Advisory  Council,  NIH   2000  –  2004     Member  of  the  Disease  PrevenUon  and  Management  Working  Group,  Advisory  Council   of  the  NaUonal  InsUtute  of  Diabetes  and  DigesUve  and  Kidney  Diseases,  NIH   2000  –  2004     Member  of  the  Advisory  Council  OperaUng  Procedures  Working  Group,  NIDDK  Advisory   Council,  NIH        
  • 13. CONSULTANT  ACTIVITIES  TO  THE  AMERICAN  DIABETES  ASSOCIATION   1984  -­‐  1985     Chairman,  PaUent  EducaUon  Commioee,  American  Diabetes  AssociaUon,  North  Carolina   1984  -­‐  1985     President,  American  Diabetes  AssociaUon,  Pio  County  Chapter,  North  Carolina   1985  -­‐  1986     Chairman,  PaUent  EducaUon  Commioee,  American  Diabetes  AssociaUon,  North  Carolina   Affiliate   1988  -­‐  1991     Member,  Professional  EducaUon  Commioee,  American  Diabetes  AssociaUon   1989-­‐1991     Member,   Commioee   on   ScienUfic   and   Medical   Profession.     American   Diabetes   AssociaUon   1992       Member,   Grant   Review   Panel,   Studies   on   GeneUcs   in   NIDDM,   American   Diabetes   AssociaUon,  New  York,  NY.       1989-­‐1991     Master   Faculty,   Clinical   EducaUon   Program,   "Managing   Diabetes   in   the   1990's,"   American  Diabetes  AssociaUon.   1990  -­‐  1991     President  Elect,  American  Diabetes  AssociaUon,  North  Carolina  Affiliate   1991  -­‐  1992     President,  American  Diabetes  AssociaUon,  North  Carolina  Affiliate   1992  -­‐  1996     Member,  Board  of  Directors,  American  Diabetes  AssociaUon,  Pennsylvania  Affiliate   1992  -­‐  1996     Member,   Professional   EducaUon   Commioee,   American   Diabetes   AssociaUon,   Pennsylvania  Affiliate   1993       Panel  member,  Consensus  Development  Conference  on  the  Treatment  of  Hypertension   in  Diabetes,  American  Diabetes  AssociaUon   1993  -­‐  1996     Member  of  the  Academic  Steering  Commioee,  Professional  Diabetes  Academy   1994  -­‐  1996     Chairman,   ScienUfic   and   Medical   MeeUngs   Oversight   Commioee   of   the   American   Diabetes  AssociaUon   1994  -­‐  1996     Member,  Professional  SecUon  Advisory  Panel  of  the  American  Diabetes  AssociaUon   MEDICAL  SCHOOL  COMMITTEES   1985  -­‐  1986     Member,  Policy  and  Review  Commioee  on  Human  Research,  East  Carolina  University   1985  -­‐  1986     Member,  House  Staff  EvaluaUon  Commioee,  East  Carolina  University   1985  -­‐  1991     Member,  Human  Organ  Transplant  Commioee,  East  Carolina  University   1985  -­‐  1991     Member,   Department   of   Medicine   Research   Advisory   Commioee,   East   Carolina   University   1986  -­‐  1987     Member,  RadiaUon  Safety  Commioee,  East  Carolina  University  
  • 14. 1986  -­‐  1987     Member,  InsUtuUonal  Review  Commioee,  Pio  County  Memorial  Hospital   1987  -­‐  1988     Member,  Dean's  Search  Commioee  (Elected  by  the  Faculty),  East  Carolina  University   1987  -­‐  1991     Member,  Jacob  Furth  Prize  Commioee,  East  Carolina  University   1989  -­‐  1990     Chairman,   Ad   Hoc   Commioee,   Clinical   Research   Center,   School   of   Medicine,   East   Carolina  University   1989-­‐1990     Member,   Ad   Hoc   Commioee,   Medical   School   Core   Laboratory   FaciliUes.     School   of   Medicine,  East  Carolina  University   1991       Member,  Search  Commioee  for  Chairman  of  the  Department  of  Medicine  (Elected  by   the  faculty),  East  Carolina  University   1995  -­‐  1996     Member,   University   Advisory   Commioee   on   InternaUonal   Affairs,   Thomas   Jefferson   University   1995  -­‐  1996     Secretary,  Jefferson  Faculty  FoundaUon  ExecuUve  Commioee,  Jefferson  Medical  College   1995       Member,  Jefferson  Faculty  FoundaUon  Finance  Commioee,  Jefferson  Medical  College   OTHER  CONSULTANT/COMMITTEE  WORK   1986-­‐1996     Ad  Hoc  Reviewer,  Research  Grants  Program.    Veterans  AdministraUon,  Washington,  DC   1988  -­‐  1992     Member   of   the   Medical   Science   Review   Commioee,   Juvenile   Diabetes   FoundaUon   InternaUonal   1989-­‐1999     Ad  Hoc  Reviewer,  NaUonal  Science  FoundaUon.    Washington,  DC   1989-­‐1991     Member,  Board  of  Medical  Advisors.    Amylin  CorporaUon,  San  Diego,  CA   1992  -­‐  1996       Member,  Board  of  Trustees,  Methodist  Hospital,  Philadelphia,  PA   1992  -­‐  1996     Member,  Board  of  Trustees,  Magee  RehabilitaUon  Hospital,  Philadelphia,  PA   1992  -­‐  1996     Member,  Board  of  Directors,  Philadelphia  Endocrine  Society   1993  -­‐  1996     Member,  Boston  Obesity/NutriUon  Research  Center  ScienUfic  Advisory  Group   1993  -­‐  1994     Member,  EducaUon  Commioee,  Professional  Diabetes  Academy   1994  -­‐  1996     Member,  Academic  Advisory  Commioee  of  the  Pfizer  VisiUng  Professorship  Program  in   Diabetes  Management   1994       Member,   Commioee   on   Faculty   and   Researchers,   Interamerican   College   of   Physicians   and  Surgeons  
  • 15. 2001  -­‐  2005     Member,  JDRF  Management  Advisory  Board   2004         Member,  American  Obesity  AssociaUon  Advisory  Board   PROFESSIONAL  SOCIETIES/MEMBERSHIPS   1976  -­‐2010     Member,  American  Society  of  Internal  Medicine   1977  -­‐2010     Member,  American  College  of  Physicians   1979  -­‐  2010                                Member,  American  FederaUon  for  Clinical  Research   1980  -­‐  2010     Member,  American  Diabetes  AssociaUon   1980  -­‐  2010     Member,  Endocrine  Society   1984  -­‐  2010     Member,  American  AssociaUon  for  the  Advancement  of  Science   1984  -­‐  2010     Member,  American  Medical  AssociaUon   1984  -­‐  1992     North  Carolina  Medical  Society   1988  -­‐  2010     Member,  American  Society  for  Clinical  InvesUgaUon  (Young  Turk)   1991  -­‐  2010     Member,  Sigma  Xi,  The  ScienUfic  Research  Society   1992  -­‐  1997     Pennsylvania  Medical  Society   1992  -­‐  1997     Philadelphia  County  Medical  Society   1992  -­‐  1997     College  of  Physicians  of  Philadelphia   1992  -­‐  2010     Charter  Member,  American  AssociaUon  of  Clinical  Endocrinologists   1993  -­‐  2010     Fellow,  American  College  of  Physicians   1993  -­‐  2010                                Member,  North  American  AssociaUon  for  the  Study  of  Obesity   1993  -­‐  2010     Member,  Professional  Diabetes  AssociaUon   1995  -­‐  2010     Member,  Society  of  Ibero  LaUn  American  Medical  Professionals   1996  -­‐  1997     Member,  American  Society  for  Clinical  Pharmacology  and  TherapeuUcs   2000  -­‐  2010     Member,  AssociaUon  of  American  Physicians  (Old  Turk)  
  • 16. SPECIAL  POST  GRADUATE  EDUCATION   1992       Program  for  Chiefs  of  Clinical  Services,  Harvard  School  of  Public  Health   1993       Program  for  ExecuUves  in  Managed  Care,  Harvard  School  of  Public  Health   VISITING  PROFESSORSHIPS  AND  SPECIAL  LECTURES   Invited  Speaker.  "Mechanism  of  Insulin  Resistance  in  Uremia."  University  of  Pennsylvania.  Philadelphia,  PA,  1981   Invited  Speaker.  "Insulin  Binding  and  Processing  in  Isolated  Rat  Hepatocytes."  University  of  Virginia.  Charlooesville,   VA,  1981   Invited  Speaker.  "Insulin  Resistance  in  Uremia."  University  of  South  Florida.  Tampa,  FL,  1982   Invited  Speaker.  "Insulin  Resistance  in  Uremia."  Duke  University  School  of  Medicine.  Durham,  NC,  1982   Program  Chairman.  "The  Diagnoses  and  Treatment  of  Type  II  Diabetes."  American  Diabetes  AssociaUon  and  East   Carolina  University  School  of  Medicine.  Greenville,  NC,  1984   Invited  Speaker.  "Management  of  Type  II  Diabetes."  At  the  "First  Congress  in  Washington,  DC  of  the  Interamerican   College  of  Physicians  and  Surgeons."  Washington,  DC,  1984   Invited  Speaker.  "Mechanism  of  Insulin  AcUon"  and  "Hyperlipidemia  in  Diabetes."  The  Third  Annual  ScienUfic  Panel   and  the  University  of  Zulia.  Maracaibo,  Venezuela,  1985   Invited  Speaker.  "Gastric  Bypass:  A  Human  Model  to  Study  Diabetes."  Duke  University  School  of  Medicine.  Durham,   NC,  1985   VisiUng  Professor.  "Mechanism  of  Insulin  Resistance  in  the  Human  Liver  from  PaUents  with  NIDDM."  University  of   Rochester  School  of  Medicine  and  DenUstry.  Rochester,  NY,  1986   Moderator.  "Learn  by  Sharing."  PaUent  EducaUon  Program  of  the  American  Diabetes  AssociaUon,  North  Carolina   Affiliate.  Raleigh,  NC,  1985   Invited   Speaker.   "DiabeUc   Emergencies"   and   "Office   Management   of   Type   II   Diabetes."   14th   Annual   Beach   Workshop.  Myrtle  Beach,  SC,  1986   Invited   Speaker.   "Insulin   Receptor   Kinase   AcUvity   in   Human   Liver,   Muscle,   and   Adipose   Tissue."   Lilly   Research   Laboratories.  Indianapolis,  IN,  1986   VisiUng  Professor.  "ECU  Diabetes  Program  Project."  Diabetes  Branch  of  the  NaUonal  InsUtutes  of  Health,  Bethesda,   MD,  1986   VisiUng  Professor.  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes."  Geriatric  Research  Center,  Johns  Hopkins   University  School  of  Medicine.  BalUmore,  MD,  1986   VisiUng  Professor.  "The  Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes."  Department  of  Pathology,  University   Complutense  School  of  Medicine.  Madrid,  Spain,  1986  
  • 17. Invited  Speaker.  "The  Human  Endocrine  System:  A  Brief  Review."  At  the  Fourth  Annual  Biotechnology  Symposium."   East  Carolina  University  School  of  Medicine.  Greenville,  NC,  1986   VisiUng   Professor.   "Insulin   Receptor   Kinase   in   Important   Target   Tissues   for   Insulin   in   Type   II   Diabetes   Mellitus."   Department  of  Medicine,  University  of  Rochester  School  of  Medicine  and  DenUstry.  Rochester,  NY,  1987   Invited   Speaker.   "The   Insulin   Receptor   and   Liver,   Skeletal   Muscle,   and   Adipose   Tissue   from   Humans   with   and   without  Type  II  Diabetes."  Lilly  Diabetes  Care  InternaUonal  Symposium.    Indianapolis,  IN,  1987   Invited   Speaker.   "Mechanisms   of   Insulin   Resistance   in   Type   II   Diabetes."   At   the   "NaUonal   InsUtutes   of   Health   Centennial,  Nurturing  CreaUve  Research  Genius  for  Biomedicine."  Duke  University  School  of  Medicine.  Durham,   NC,  1987   Symposium   Chairman.   "Diabetes   Mellitus:   Management   in   Pregnancy   and   Childhood."   American   Diabetes   AssociaUon  and  East  Carolina  University  School  of  Medicine.  Greenville,  NC,  1987   Invited  Speaker.  "Type  II  Diabetes  Mellitus:  Treatment  and  ComplicaUons."  The  XI  Interamerican  Medical  Congress   of  the  Spanish-­‐American  Medical  Society.  New  York,  NY,  1987   VisiUng  Professor.  "Mechanisms  of  Insulin  Resistance  in  Type  II  Diabetes."  University  of  Virginia  Diabetes  Center,   Charlooesville,  VA,  1987   VisiUng   Professor.   "Role   of   Insulin   Receptor   Tyrosine   Kinase   in   Insulin   Resistance."   Glaxo   Research   Laboratory.   Research  Triangle  Park,  NC,  1987   Invited   Speaker.   "Advances   in   the   Treatment   of   Type   II   Diabetes."   At   the   XII   Annual   Conference   of   the   North   Carolina  Academy  of  Physicians."  Wrightsville,  NC,  1988   Invited   Speaker.   "Carbohydrate   Metabolism   in   Diabetes."   At   the   "IX   Annual   Congress   of   the   Spanish   Society   of   Diabetes."  Barcelona,  Spain,  1988   Invited  Speaker.  "Current  Views  of  EUology  of  Type  II  Diabetes:  Are  We  Gewng  There?"  At  "Diabetes  Update  1988."   American  Diabetes  AssociaUon  and  East  Carolina  University  School  of  Medicine.  Southern  Pines,  NC,  1988   Invited  Speaker.  "The  Insulin  Receptor  in  Obesity  and  NIDDM:  A  New  Target  for  Clinical  and  Basic  Research."  At  a   symposium  on  the  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes"  70th  Annual  MeeUng  of  the  Endocrine   Society.  New  Orleans,  LA,  1988   VisiUng   Professor   and   Clinical   Scholar.   Lilly   task   force   on   "Early   RecogniUon   and   PrevenUon   of   Diabetes."   Lilly   Research  Laboratories.  Indianapolis,  IN,  1988   Invited  Speaker.  "DiabeUc  Emergencies."  North  Carolina  Family  Physician's  Annual  MeeUng.  Wrightsville  Beach,  NC,   1988   Invited   Speaker.   "Diabetes."   Geriatric   Medicine   Board   Review.   East   Carolina   University   School   of   Medicine.   Greenville,  NC,  1988   VisiUng  Professor.  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes."  Veterans  AdministraUon  Medical  Center  at   Georgetown  University.  Washington,  DC,  1988  
  • 18. Invited   Speaker.   "Insulin   Receptor   Kinase   AlteraUons."   At   the   "AcUon   of   Insulin   and   Related   Growth   Factors   in   Diabetes   Mellitus."   CelebraUng   Joslin's   90th   Anniversary.   Joslin   Diabetes   Center   and   Harvard   Medical   School.   Boston,  MA,  1988   VisiUng  Professor.  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes."  University  of  Illinois  Chicago,  IL,  1988   VisiUng  Professor.  "Insulin  Resistance."  University  of  California,  San  Diego,  CA,  1988   Invited  Speaker.  "DevastaUon  of  the  Disease:  Type  II  Diabetes."  Third  Hispanic  Medical  Congress.  Washington,  DC,   1988   VisiUng  Professor.  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes"  and  "Chronic  ComplicaUons  of  Diabetes."   Diabetes  Branch  of  the  NaUonal  InsUtutes  of  Health.  Bethesda,  MD,  1988   VisiUng  Professor.  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes"  and  "Chronic  ComplicaUons  of  Diabetes."   University  of  Colorado  Health  Sciences  Center.  Denver,  Colorado,  1988   VisiUng   Professor.   "Mechanism   of   Insulin   Resistance   in   Type   II   Diabetes."   Diabetes   Clinical   Research   InsUtute,   Charlooesville,  VA,  1989   VisiUng  Professor.  "The  Insulin  Receptor:  A  New  Target  For  Basic  and  Clinical  InvesUgaUons."  Research  Seminar,   Emory  University,  Atlanta,  GA,  1989   VisiUng   Professor.   "Mechanism   of   Insulin   Resistance   in   Type   II   Diabetes."   Diabetes   Center   of   Eastern   Virginia,   Norfolk,  VA,  1989   Invited  Speaker.  "Mechanism  of  Insulin  AcUon."  Inter-­‐University  Post-­‐Graduate  course  on  Molecular  Mechanism  of   the  Endocrine  System,  Fundacion  Ramon  Areces,  Madrid,  Spain,  1989   Keynote  Speaker.  "The  Pathogenesis  of  Obesity"  and  "Meet  the  Professor:  Problem  Case  Discussion."  At  Diabetes   Mellitus  -­‐  Challenges  in  the  1990's."  American  Diabetes  AssociaUon,  Hilton  Head  Island,  SC,  1989   Invited   Speaker.   "Clinical   and   Physiological   Correlates   of   Glucose   Transport   in   Obesity   and   Diabetes"   at   "The   Symposium  in  FronUers  in  the  Molecular  and  Cellular  Biology  and  Glucose  Transport."  49th  Annual  MeeUng  and   ScienUfic  Sessions,  American  Diabetes  AssociaUon,  1989   Invited  Speaker.  "Insulin  Resistance  in  Obesity:  Towards  a  Molecular  Approach."  UCLA  Symposium  on  Molecular   and  Cellular  Biology,  Keystone,  Colorado,  1989   Keynote   Speaker.   "Advances   in   Diabetes   Mellitus"   at   the   Mexican   Society   of   NutriUon   and   Endocrinology,   Monterey,  Mexico,  1989   Keynote  Speaker.  "Obesity  and  Insulin  Resistance"  and  "Meet  the  Professor:  Diabetes  Mellitus  and  Hypertension"   at  the  IV  InternaUonal  Congress  of  Medicine,  Victoria,  Mexico,  1989   Invited  Speaker.  "Studies  on  the  Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes."  Merck,  Sharp,  &  Dohme  Co.   Rahway,  NJ,  1989   Invited   Speaker.   "The   Insulin   Receptor   and   Post   Receptor   in   Liver   in   NIDDM:   Effects   of   Sulfonylureas."   Fourth   InternaUonal  Conference  on  Diabetes.  University  of  Virginia,  Charlooesville,  VA,  1989  
  • 19. Keynote  Speaker.  "Cellular  AlteraUons  in  Liver,  Muscle,  and  Adipose  Tissues  Responsible  for  Insulin  Resistance  in   Diabetes."   MeeUng   of   the   Diabetes   Treatment   Centers   of   American   FoundaUon.   1989   Annual   Physicians   Conference.  Palm  Desert,  CA,  1989   Invited  Speaker.  "Diabetes  is  a  Serious  Disease"  42nd  Annual  ScienUfic  Assembly  of  the  North  Carolina  Academy  of   Family  Physicians.  Greensboro,  NC,  1990   Invited   Speaker.   "Cellular   AlteraUons   in   Liver,   Muscle,   and   Adipose   Tissue   Responsible   for   Insulin   Resistance   in   NIDDM."  Hershey  Medical  Center,  Hershey,  PA,  1990   Invited  Speaker.  "AlteraUons  in  Insulin  Receptors  and  Glucose  Transporters  in  Obese  and  DiabeUc  Humans,"  at  the   Satellite  MeeUng  of  the  XI  Amsterdam  InternaUonal  Congress  of  Pharmacology,  "Pathophysiology  and  Treatment  of   Diabetes  Mellitus"  Montpellier,  France,  1990   Invited  Speaker.  "Altered  Coupling  of  the  Insulin  Receptor  with  Gi  Protein  in  the  Liver  from  PaUents  with  NIDDM"  at   the  InternaUonal  Symposium  on  Obesity  and  Diabetes  Mellitus,  Nagoya,  Japan,  1990   Invited   Speaker.   "Insulin   AcUon   in   Adipose   Tissue   and   Muscle   in   Human   Obesity   and   Diabetes"   at   the   6th   InternaUonal  Congress  on  Obesity,  Kobe,  Japan,  1990   Invited  Speaker,  "Diagnosis  and  Treatment  of  Diabetes  Mellitus"  and  "Insulin  Resistance  in  Obesity  and  Diabetes   Mellitus"  at  the  LII  NaUonal  Medical  Congress,  San  Jose,  Costa  Rica,  1990   Invited  Speaker,  "Post-­‐Receptor  Defect  in  Type  II  Diabetes"  American  Diabetes  AssociaUon,  Minneapolis  Affiliate,   Minneapolis,  MN,  1990   Invited  Speaker,  "G-­‐Proteins  in  Diabetes"  at  the  Mayo  Clinic,  Rochester,  NY,  1990   Invited   Speaker,   "Overview   of   AlteraUons   in   Insulin   AcUon   in   Human   Diabetes"   at   the   UCLA   Symposium   on   Molecular  and  Cellular  Biology,  Park  City,  Utah,  1991   Invited  Speaker,  "Mechanism  of  Insulin  Resistance  in  NIDDM."  Miles  Laboratories,  West  Haven,  ConnecUcut,  1991   Invited  Speaker,  "Mechanisms  and  Management  of  Type  II  Diabetes."  New  Mexico  Metabolism  Symposium  1991.   Taos,  New  Mexico,  1991   Invited  Speaker,  "Mechanism  of  Insulin  Resistance  in  Type  II  Diabetes.  "Baylor  College  of  Medicine,  Houston,  Texas,   1991   Invited  Speaker,  "Diabetes  Mellitus  PrevenUon  in  the  High  Risk  PaUent,"  at  the  "Current  Advances  in  NutriUonal   Medicine  and  Disease  PrevenUon."  Harvard  Medical  School,  Boston,  MA,  1991   Invited  Speaker,  "NIDDM:  Insulin  Resistance  vs.  Insulin  SecreUon."  NJ  Affiliate  of  the  ADA,  Jamesburg,  NJ,  1991   Keynote  Speaker,  "Diabetes  in  the  90's."  American  Diabetes  AssociaUon,  NC  Affiliate,  Raleigh,  NC,  1991   Invited  Speaker,  "Insulin  Resistance  in  NIDDM."  University  of  Chicago,  Chicago,  IL,  1991   Invited  Speaker,  "Carbohydrate  Metabolism  in  Obesity  and  Diabetes."  NutriUon  and  Diabetes  Mellitus:  Focus  for   the  1990's.  A  Satellite  Symposium  of  the  14th  IDF  Congress.  BalUmore,  MD,  1991  
  • 20. Invited   Speaker,   "Physiology   of   Insulin   AcUon   in   Muscle."   14th   InternaUonal   Diabetes   FederaUon   Congress,   Washington,  DC,  1991   Invited  Speaker,  "Mechanism  of  Insulin  AcUon."  Satellite  Symposium,  14th  IDF  Congress,  Airily,  VA,  1991   VisiUng   Professor,   "Cellular   AlteraUons   in   Liver,   Skeletal   Muscle,   and   Adipose   Tissue   Responsible   for   Insulin   Resistance  in  Obesity  and  Type  II  Diabetes."  Symposium  organized  by  the  USSR  Academy  of  Medical  Sciences  and   the  USSR  Ministry  of  Health,  Moscow,  Russia,  1991   Invited   Speaker,   "The   IGF-­‐1   Receptor   in   NIDDM:   A   Pathway   to   Bypass   Insulin   Resistance?"   39th   Annual   Clinical   Society  ScienUfic  MeeUng  of  the  American  Diabetes  AssociaUon,  New  York  Downstate  Affiliate,  New  York  City,  1991   Invited   Speaker,   "Mechanism   of   Insulin   Resistance   in   Obesity."   Workshop   sponsored   by   the   NaUonal   Diabetes   Advisory  Board,  NaUonal  InsUtutes  of  Health,  Arlington,  VA,  1991   Invited  Speaker,  "Syndrome  X."    11th  Annual  Day  of  Diabetes,  American  Diabetes  AssociaUon,  Columbus,  Georgia,   1992   Invited  Speaker,  "Insulin  Resistance  in  Obesity  and  Non-­‐Insulin  Dependent  Diabetes:    Cause  or  Effect."    Western   Metabolism  Club,  Carmel,  California,  1992   VisiUng   Professor,     "Fat   1992",   Grand   Rounds,   Hospital   of   the   University   of   Pennsylvania,   Philadelphia,   Pennsylvania,  1992   Invited  Speaker,  "Alteraciones  a  nivel  de  receptor  y  post  receptor  en  la  obesidad,"  XXV  Congreso  Nacional  de  la   Sociedad  Española  de  Ciencias  Fisiológicas,  Cordoba,  Spain,  1992   Keynote  Speaker,  "Aspectos  moleculares  de  la  diabetes  mellitus  no  insulinodependiente",  VIII  Congreso  Asociación   LaUnoamericana  de  Diabetes,  Buenos  Aires,  ArgenUna,  1992   Simposium  Speaker,  "Resistencia  insulinica:  su  rol  en  diversos  síndromes,"  VII  Congreso  Asociación  LaUnoamericana   de  Diabetes,  Buenos  Aires,  ArgenUna,  1992   VisiUng  Professor,  "Weight  Loss:    Is  it  a  Miracle?",  Cooper  Hospital/University  of  Medicine  and  DenUstry  of  New   Jersey,  Robert  Wood  Johnson  Medical  School,  Camden,  New  Jersey,  1992   VisiUng  Professor,  "Insulin  Resistance  in  Type  II  Diabetes",  University  of  Piosburgh,  Piosburgh,  Pennsylvania,  1992   VisiUng  Professor,  "Pharmacological  methods  to  bypass  insulin  resistance",  Department  of  Biochemistry,  University   of  Medicine  and  DenUstry  of  New  Jersey/School  of  Osteopathic  Medicine,  Stralord,  New  Jersey,  1992   Invited   Speaker,   "Insulin   Resistance   in   Type   II   Diabetes",   InternaUonal   Diabetes   FederaUon   Congress   and   the   Dominican  Republic  AssociaUon  of  Endocrinology,  Santo  Domingo,  Dominican  Republic,  1993   VisiUng  Professor,  "Insulin  Resistance",  State  University  of  New  York  Health  Science  Center  at  Brooklyn,  Brooklyn,   New  York,  1993   VisiUng   Professor,   "Insulin   Resistance:     A   target   for   the   Clinical   and   Basic   InvesUgator",   The   Milton   S.   Hershey   Medical  Center  of  the  Pennsylvania  State  University,  Hershey,  Pennsylvania,  1993   Invited   Speaker,   "Beyond   the   Basics:     Neuropathy",   the   13th   Annual   Diabetes   Update   '93   -­‐   American   Diabetes   AssociaUon,  Philadelphia,  Pennsylvania,  1993  
  • 21. Invited  Speaker,  "Obesity:    A  Disease  of  the  Adipose  Tissue",  NaUonal  InsUtutes  of  Health,  Bethesda,  Maryland,   1993   Invited  Speaker,  "The  ABCs  of  Thyroid  Disease",  Eastern  Shore  Medical  Symposium,  Rehoboth  Beach,  Delaware,   1993     VisiUng   Professor,   "Gene   Therapy   for   Insulin   Resistance",   Department   of   Biochemistry,   School   of   Medicine,   Universidad  Complutense,  Madrid,  Spain,  1993   Keynote  Speaker,  "Diabetes  in  LaUnos"  8th  Hispanic  Medical  Congress.    The  Interamerican  College  of  Physicians  and   Surgeons,  San  Juan,  Puerto  Rico,  1993     Invited  Speaker,  "The  TranslaUon  of  the  DCCT  to  the  Care  of  PaUents  with  Type  II  Diabetes  Mellitus"  The  Opening   Symposium  of  the  Joslin  Center  for  Diabetes  at  Jefferson  Medical  College  and  Wills  Eye  Hospital,  Philadelphia,  1994   Invited   Speaker,   "Weight   Loss   in   Severely   Obese   Subjects   Prevents   Type   II   Diabetes"     InternaUonal   Symposium   sponsored  by  the  Chinese  NutriUon  Society  and  Shanghai  NutriUon  Society.    Beijing,  China,  1994   Invited  Speaker,  "Thyroid  Nodules"  Diabetes-­‐Endocrine  Symposium,  Medical  College  of  Pennsylvania,  Philadelphia,   Pennsylvania,  1994   Leadership   Workshop:     "TherapeuUc   Choices   in   NIDDM”   54th   Annual   MeeUng,   American   Diabetes   AssociaUon,   New  Orleans,  1994   Invited   Speaker,   "Morbid   Obesity   and   Diabetes"   7th   InternaUonal   Congress   of   Obesity   Satellite   Symposium   on   Surgical  Treatment  of  Obesity,  Montreal,  Quebec,  Canada,  1994   Keynote  Speaker,  "Insulin  Resistance  from  the  laboratory  to  the  bedside",  XVI  Internal  Medicine  Chilean  Congress,   SanUago,  Chile,  1994   Symposium  Speaker,  "Current  and  future  treatment  of  Diabetes  Mellitus",  XVI  Internal  Medicine  Chilean  Congress,   SanUago,  Chile,  1994   Invited  Speaker,  "PrevenUon  of  diabetes:    Is  it  possible?  ",  XVI  Internal  Medicine  Chilean  Congress,  SanUago,  Chile,   1994   Invited  Speaker,  "Insulin  Analogs"  American  Diabetes  AssociaUon,  Northern  Illinois  Affiliate’s  Thirty-­‐Seventh  Annual   Professional  Symposium,  Chicago,  1994   Invited  Speaker,  "The  TranslaUon  of  the  DCCT  to  the  Care  of  the  PaUent  with  Type  II  Diabetes  Mellitus",  The  Third   Annual  Controversies  in  Ambulatory  Care  Medicine,  Philadelphia,  1994   VisiUng  Professor,  "PrevenUon  of  Type  II  Diabetes:    The  Challenge  of  the  Next  Decade",  Medical  Grand  Rounds,   UMDNJ-­‐Robert  Wood  Johnson  Medical  School,  New  Brunswick,  NJ,  1995   VisiUng  Professor,  “The  PromoUon  of  the  Adipocyte:    from  storage  to  an  endocrine  cell”,  Grand  Rounds,  University   of  Southern  California  School  of  Medicine,  Los  Angeles,  CA,  1995   VisiUng   Professor,   “¿Es   el   adiosito   inteligente?”,   Consejo   Superior   de   InvesUgaciones   Cien~ficas,   Madrid,   Spain,   1995  
  • 22. Leadership  Workshop:    "Insulin  AcUon  Enhancers”,  55th  Annual  MeeUng,  American  Diabetes  AssociaUon,  Atlanta,   Georgia,  1995   Invited  Speaker,  “Impact  of  weight  loss  by  surgery  on  metabolic  fitness”,  FASEB  Summer  Conference  on  GeneUc  and   Behavioral  Influences  on  Nutrient  Metabolism  and  Obesity,  Copper  Mountain,  Colorado,  1995   VisiUng  Professor,  “Ob  protein  resistance  in  human  obesity”,  University  of  Chicago,  Chicago,  Illinois,  1995   Plenary  Speaker,  “Studies  of  LepUn  in  Human  Subjects”,  NAASO  MeeUng,  Baton  Rouge,  Louisiana,  1995   Symposium  Speaker,  “The  Gut  and  NIDDM”,  Precose  Specialist  InvesUgator  MeeUng,  Lincolnshire,  IL,  1995   VisiUng  Professor,  “¿Terapia  molecular  de  la  diabetes  o  de  la  obesidad?”,  V  Congreso  de  Ciencias  FarmacéuUcas,   Madrid,  Spain,  1995   Symposium   Speaker,   “Obesidad   e   insulino   resistencia”,   Sociedad   Mexicana   de   Nutrición   y   Endocrinologia,   Guanajuato,  Mexico,  1995   Symposium  Speaker,  “LepUn:    The  sensor  of  either  fact  mass  or  energy  balance?”,  American  Society  for  Parenteral   and  Enteral  NutriUon,  Washington,  DC,  1996   Symposium  Speaker,  “Advances  en  Fisiopatologia  de  la  Obesidad”,  Canary  Islands,  Spain,1996   Invited  Speaker,  “The  Ob  Gene  in  Human  Obesity”,  Western  Metabolism  Club,  Carmel,  CA,  1996   Invited  Speaker,  “Ob  Protein  in  Human  Obesity”,  IBC’s  Second  Annual  InternaUonal  Symposium,  Washington,  DC,   1996   Invited   Speaker,   “New   Insights   into   the   Pathophysiology   and   Therapy   of   Obesity:     The   LepUn   Story”,   Sixteenth   MeeUng  of  the  InternaUonal  ScienUfic  Commioee  on  Diabetes,  Cologne,  Germany,  1996   Invited   Speaker,   “Obesity:     A   GeneUc   Disease?”,   Fourth   ScienUfic   Course   in   PancreaUc   Islet   Physiology   and   Pathology,  Barcelona,  Spain,  1996   Invited  Speaker,  “Obesity:    What  Can  be  Done?”,  Clinical  Endocrinology,  Harvard  Medical  School,  Boston,  MA,  1996   Invited   Speaker,   "Human   Obesity:     What   Have   We   Learned   from   Recent   GeneUc   Insights?",     Biomedicine   '96,   Washington,  D.C.,  1996   VisiUng  Professor,  "LepUn:    The  Tale  of  an  Obesity  Gene,  Part  II:    Rx:    LepUn  Sc,  qday  and  eat  anything  you  want  ,   East  Carolina  University,  Greenville,  NC,  1996   Invited   speaker,   "LepUn   Physiology   and   Pathophysiology   in   Man",   American   Society   for   Clinical   InvesUgaUon,   Washington,  D.C.,  1996   Symposium  Speaker,  "Molecular  therapy  of  obesity  or  diabetes?    That  is  the  quesUon",  XIII  MeeUng  of  the  Spanish   Diabetes  Society,  Oviedo,  Spain,  1996   Keynote  speaker,  "LepUn:    The  tale  of  an  obesity  gene:  American  Diabetes  AssociaUon,  Amelia  Island,  Florida,  1996   Symposium  Speaker:  “Obesity  and  Diabetes”  4th  Annual  Congress  on  Women’s  Health,  Washington,  D.C.,  1996   Invited  Speaker,  “LepUn:  The  Tale  of  an  Obesity  Gene”  Annual  Research  Symposium,  The  InsUtute  of  NutriUon,   University  of  North  Carolina,  Chapel  Hill,  NC,  1996  
  • 23. Invited   Speaker,   “Ob   Protein   in   Human   Obesity”     IBC’s   Third   InternaUonal   Symposium   -­‐   Obesity   -­‐   Advances   in   Understanding  and  Treatment.  San  Diego,  CA,  1996   Invited  Speaker,  “MeeUng  the  Needs  of  paUents:  Emerging  OpUons  in  Diabetes  Care”.    34th  Annual  MeeUng  of  the   European  AssociaUon  for  the  Study  of  Diabetes.  Vienna,  Austria,  1996   Invited  Speaker.  “Obesity  as  a  Metabolic  Disease”.    6th  Annual  Turamberry  Conference.  Aventura,  Florida,  1996   Invited   Speaker.     “The   ob   Gene   Product   and   Nutrient   Balance”.   North   American   AssociaUon   for   the   Study   of   Obesity.  Breckenridge,  Colorado,  1996   Invited  Speaker.    XXVI  Congreso  de  la  Asociación  Española  de  Pediatria.  Valencia,  Spain,  1996   Invited  Speaker.    Human  Obesity:  Beyond  LepUn  ProducUon.  InternaUonal  Congress  on  AnU-­‐Obesity  Drug  Targets.   Cambridge,  MA.,  1996   Invited   Speaker.     Insulina   y   lepUna:   La   Extraña   Pareja.   VIII   Congreso   Sociedad   Valenciana   de   Endocrinologia,   Diabetes  y  nutrición.  Valencia,  Spain,  1996     Invited  Speaker.    Chapter  One  in  the  Story  of  LepUn  in  Humans.  American  Society  for  Clinical  Pharmacology  and   TherapeuUcs.  San  Diego,  CA,  1997   Invited  Speaker.    “Pathophysiology  of  Obesity”.    Symposium  of  the  German  Endocrine  Society.  Lübeck,  Germany,   1997.   Invited   Speaker.     “LepUn:   The   Second   Year”.     2nd   World   Conference   of   the   InternaUonal   Society   for   Molecular   NutriUon  and  Therapy.    Winnipeg,  Canada,  1997.   Invited  Speaker.    "LepUn:  From  Rodents  to  Humans".    InternaUonal  Diabetes  FederaUon  Congress,  Helsinki,  Finland,   1997   Invited   Speaker.     “LepUn:   The   New   Lean   Gene”.     European   Congress   of   Clinical   Chemistry   “Medlab97”,   Basel,   Switzerland,  1997   Invited  Speaker.    Grand  Rounds.    "LepUn:  From  Rodents  to  Humans".    Tulane  University,  New  Orleans,  Louisiana,   1997   Invited   Speaker,   Plenary   Session.     "Current   and   Future   ImplicaUons   For   the   Use   of   LepUn   in   the   Treatment   of   Obesity".    NAASO  Annual  MeeUng,  Cancun,  Mexico,  1997   Invited  Speaker,  Conferencia    “Diabetes,  obesity  y  lepUn”.    Simposia  Harvard  -­‐  Joslin  -­‐  SBD,  XI  Congreso  Brasileño  de   Diabetes,  Porto  Alegre,  Brazil  1997   Medical  Grand  Rounds  -­‐  “The  Role  of  LepUn  in  Body  Weight  RegulaUon”.    The  University  of  Texas.  San  Antonio,  TX,   1997   Research  Seminar:  “Strategies  for  the  treatment  of  type  II  diabetes”.    Garvan  InsUtute.  Sydney,  Australia,  1997   Research   Seminar:   “Recent   Advances   on   LepUn”.     The   Walter   and   Eliza   Hall   InsUtute   for   Medical   Research.     Melbourne,  Australia,  1997   Plenary  Lecturer:  “Strategies  for  the  treatment  of  Obesity”.    NAASO  and  American  Society  of  Clinical  NutriUon.     Merida,  Mexico,  1997  
  • 24. Congreso  Nacional  de  la  Sociedad  Española  de  Diabetes  y  Obesidad:  “LepUna  y  obesidad".    Caceres,  Spain,  1997   Invited   Speaker   -­‐   Bio-­‐chemistry   Seminar:   “Strategy   of   drug   discovery   for   the   treatment   of   obesity”.     Indiana   University  Medical  Center.    Indianapolis,  IN,  1998   Invited   Speaker:   American   Diabetes   AssociaUon   “LepUn   Pathway   as   a   Target   for   Treatment”.     San   Francisco,   California,  1998   Invited  Speaker:  “Addressing  the  AcceleraUng  Cost  of  Chronic  Diseases:    A  Case  Study”.    MeeUng  the  21st  century   healthcare  challenge:    A  New  Vision  for  PharmaceuUcal  InnovaUon.    PHRMA,  U.S.  Embassy.  Tokyo,  Japan,  1998   Opening  Lecture  of  the  XIV  Sociedad  Española  de  Diabetes:  “En  el  camino  a  la  cura  de  la  Diabetes”  Murcia,  Spain,   1998   Keynote  lecture:  “A  new  endocrine  cell:  Biology  and  FuncUon  of  Adipocytes”  71st  Annual  MeeUng  of  the  Japan   Endocrine  Society.    Fukuoka,  Japan,  1998   Plenary   lecture:   “LepUn:   the   Past,   Present   and   Future”.     71st   Annual   MeeUng   of   the   Japan   Endocrine   Society.     Fukuoka,  Japan,  1998   Plenary  lecture:  “From  New  Genes  to  New  Treatments”.    Satellite  Symposium  of  the  8th  InternaUonal  Congress  on   Obesity.    Paris,  France,  1998   Plenary  lecture:  “Emerging  Therapies  for  Type  II  Diabetes”.    34th  Annual  MeeUng  of  the  European  AssociaUon  for   the  Study  of  Diabetes.    Barcelona,  Spain,  1998   Conferencia  Magistral  -­‐  Hospital  Maciel:  “  LepUna  la  Voz  Del  Adiosito”.  Simposio  Obesidad  y  Diabetes  Mellitus  -­‐   Cuando  Y  Como  Intervenir.  Montevideo,  Uruguay,  1998   Conferencia   Magistral   -­‐   Hospital   Maciel:   “Intervenciones   Futuras   en   el   Manejo   de   la   Obesidad.     Montevideo,   Uruguay,  1998   Lilly  Symposium  -­‐  Temas  actuales  en  Diabetes.  “LepUna  y  Obesidad”.  Montevideo,  Uruguay,  1998   Invited   Speaker:   “Opciones   terapéuUcas   en   el   síndrome   de   insulinorresistencia”.     XI   Congreso   ArgenUno   de   Diabetes.    Cordoba,  ArgenUna,  1998   Invited  Speaker:  “LepUna  y  Obesidad”.    XI  Congreso  ArgenUno  de  Diabetes.    Cordoba,  ArgenUna,  1998   Opening   Lecture:   “LepUna:   La   voz   del   Adiosito”.     III   Curso   Sobre   InvesUgaciones   Biomedicas,   Universidad   de   Granada  y  Consejo  Superior  de  InvesUgaciones  Cien~ficas.    Granada,  Spain,  1998   Symposium  Speaker:    “New  Molecular  Target  for  the  treatment  of  Obesity”.    “VI  MeeUng  on  Lipid  Metabolism  and   Related  Pathology”    InsUtuto  Superior  de  Ciencias  da  Sande-­‐Sul.    Costa  da  Caprica,  Portugal,  1998   Symposium  Chairman  and  Speaker:    “Neuroendocrine  integraUon  of  appeUte".    Experimental  Biology  ‘99  MeeUng.     Washington,  D.C.  1999   Invited  Speaker:  "LepUn:  The  tale  of  an  obesity  gene  and  it's  applicaUon  to  children".    Building  Bright  Futures:   Neonatal,   Pediatric   and   Adolescent   NutriUon   in   the   21st   Century.     Indiana   University   School   of   Medicine,   Indianapolis,  IN.    1999  
  • 25. Symposium  Co-­‐Chairman  and  Speaker.    "On  the  trail  to  cure  obesity".    GeneUcs,  Pathophysiology  and  TherapeuUcs   on  the  Eve  of  a  Major  Conceptual  RevoluUon.    Euro-­‐Conference  InsUtute  Pasteur.    Paris,  France,  1999   Invited  Speaker:  "Insulin  Resistance:  A  target  for  drug  therapy  at  the  CMES  Ancillary  Symposium,  The  Endocrine   Society.    Toronto,  Canada,  2000   VisiUng  Professor:    “New  targets  for  the  treatment  of  obesity”.    Medical  Grand  Rounds,  University  of  Piosburgh   School  of  Medicine.    Piosburgh,  PA.    2001   Invited  Speaker:    “The  treatment  of  diabetes  in  the  new  Millennium.    Italian  Society  of  Diabetes.    Florence,  Italy,   2002   Symposium  Speaker:    “New  Drug  Therapies  for  Obesity”  at  Obesity:    Molecular  Causes   and  New  Pathways  for  Treatment  and  PrevenUon.    American  AssociaUon  for  the  Advancement  of  Science  (AAAS)   Annual  MeeUng.    Denver,  Colorado.    2003   Keynote  Speaker:    “The  Do’s  and  Do  Not’s  in  Science:    From  Fuller  Albright  to  the  Present”.  Graduate  Student   Research  Day.    East  Carolina  University.  Greenville,  NC.    2003   Symposium  Speaker:    “Obesity  and  the  Metabolic  Syndrome:    IdenUfying  Underlying  Mechanisms  and  Emerging   Therapies  for  Pharmacological  Treatment”.    PharmaceuUcal  EducaUon  Associates.    Washington,  DC.    2003.   Roundtable  ParUcipant:    “Obesity  and  Cancer”  NaUonal  Dialogue  on  Cancer.    Sponsored  by  President  George  W.   and  Barbara  Bush.    Kennebunkport,  Maine.    2003   Keynote   Speaker   and   Chairperson:     “OpportuniUes   and   Challenges   of   TherapeuUc   Development   for   Obesity”.     World  Obesity  Congress  &  Expo.    Washington,  DC.    2004   Symposium   Speaker:     “Addressing   the   Obesity   Epidemic:     From   Bench   to   Bedside   to   Market”.     The   Endocrine   Society’s  86th  Annual  MeeUng.    New  Orleans,  LA.    2004   Invited   Speaker:     “Overcoming   Diabetes:     A   Long   March   from   Discovery   to   CommercializaUon”.     The   Opening   Ceremony  of  the  Peking  University  Diabetes  Center.    Beijing,  China.    2004   Invited  Speaker:    “AnU-­‐Obesity  Drug  Development:    From  Target  IdenUficaUon  to  Launch”.    NAASO  2004  ScienUfic   MeeUng.    Las  Vegas,  NV.    2004   Invited  Speaker:    “New  Therapies  for  Diabetes”.    Leerink  Swann/MEDACorp.  Inaugural  Health  Care  Conference.     New  York,  NY.    2005   Invited  Speaker:    “Insulin  SensiUvity  Enhancers  for  the  Treatment  and  PrevenUon  of  Diabetes“  Diabetes  and  Obesity   Research  Day.    East  Carolina  University,  Brody  School  of  Medicine.    Greenville,  NC.    2005   Keynote  Speaker  and  Chairperson:    “New  OpportuniUes  and  Challenges  of  TherapeuUc  Developments  with  Obesity   and  Weight  Loss”.    World  Obesity  Congress  &  Expo.    Washington,  DC.    2005   Keynote  Speaker:    “On  the  Trail  to  ARREST  the  Progression  of  Type  2  Diabetes”    College  of  Agriculture  and  Life   Sciences,  University  of  Arizona.    Phoenix,  AZ.    2005       Keynote  Speaker:    “On  the  Trail  to  ARREST  the  Progression  of  the  Metabolic  Syndrome”    8th  Symposium  Fundacion   Lilly  “New  Approaches  to  the  Metabolic  Syndrome”    San  Lorenzo  de  El  Escorial,  Madrid.    2005   Invited  Speaker:  “May  be  difficult  at  Umes…?”  At  The  5th  NaUonal  Metabolic  Day.  Utrecht  University,    Amsterdam,   The  Nederland  2006  
  • 26. Keynote  Speaker:  “Diabesity”  13th  Annual  Kaiser  Permanente  Diabetes  Symposium.  Woodland  Hills,  CA    2007       Invited  Speaker    and  panel  member:  “Clinical  Trials,  Sewng  the  stage  for  the  future”.  At  the  inaugural  Clinical  Trial   Regional  Exchange  Group,  The  North  Carolina  Biotechnology  Center.  Greenville  NC,  2007   Post  Graduate  Course  in  Endocrinology:  “Obesity”.  At  the  Universidad  Catolica,  Montevideo,  Uruguay,  2008   Invited  Speaker:  “Peers  for  Progress”.  At  the  School  of  Medicine,  Maciel  Hospital.  Montevideo,  Uruguay,  2008   PUBLICATIONS   1. Caro,  J.F.,  A.  Besarab,  J.R.  Burke,  and  J.A.  Glennon.    Propranolol:  A  possible  role  in  the  treatment  of  renal   osteodystrophy.  Lancet  II:451,1978.   2. Caro,  J.F.,  and  A.  Besarab.  Propranolol  therapy  for  hyperparathyroidism.  Lancet  II:827,1978.   3. Caro,  J.F.,  A.W.  Meikle,  J.H.  Check,  and  S.N.  Cohen.  "Normal  suppression"  to  dexamethasone  in  Cushing's   disease:  An  expression  of  decreased  metabolic  clearance  for  dexamethasone.  J.  Clin.  Endocrinol.  Metab.   47:667,1978.   4. Ballas,   S.K.,   J.F.   Caro,   and   O.   Miguel.   Quinidine-­‐induced   hemolyUc   anemia:   Immunohematologic   characterizaUon.  Transfusion  18:215,1978.   5. Besarab,  A.,  and  J.F.  Caro.  Mechanism  of  hypercalcemia  in  malignancy.  Cancer  6:2276,1978.   6. Caro,  J.F.,  A.  Besarab,  and  J.A.  Glennon.    SymptomaUc  hypocalcemia  following  combined  calcitonin  and   mithramycin  therapy  for  hypercalcemia  in  malignancy.  Cancer  Treat  Reports  62:1561,1978.   7. Check,  J.H.,  J.F.  Caro,  L.  Jackson,  K.  Nowroozn  and  A.F.  Rakoff.    Clinical  mixed  gonadal  dysgenesis  without  Y   chromosome.  Am.  J.  Obstet.  Gynecol.  131:346,1978.   8. Check,  J.H.,  J.F.  Caro,  and  J.T.  Flynn.  CysUc  gynecomasUa  in  a  male  treated  with  clomiphene  citrate.  Infert.   Sterility  30:713,1978.     9. Caro,  J.F.,  A.  Besarab,  and  J.T.  Flynn.  Prostaglandin  E  and  hypercalcemia  in  breast  carcinoma:  Only  a  tumor   marker?  A  need  for  prospecUve.  Am.  J.  Med.  66:337,1979.   10. Caro,  J.F.,  H.L.  Israel,  and  J.A.  Glennon.  Galactorrhea  in  sarcoidosis:  Dynamic  studies  of  prolacUn,  growth   and  gonadotropic  hormone  levels.  Am.  J.  Med.  Sci.  277:1,1979.   11. Check,  J.H.,  J.F.  Caro,  B.  Kendall,  L.A.  Peris,  and  B.L.  Wellenback.  Cushing's  syndrome  in  pregnancy:  Effect  of   associated  diabetes  on  fetal  and  neonatal  complicaUons.  Am.  J.  Obstet.  Gynecol.  44:846,1979.   12. Check,  J.H.,  J.F.  Caro,  L.  Criden,  R.  Meltz,  and  K.  Brownstein.  Leyding  cell  responsiveness  with  gonadal  cell   resistance  to  gonadotropin  therapy  in  Kallman's  syndrome.  Am.  J.  Med.  67:495,1979.  
  • 27. 13. Caro,   J.F.,   J.H.   Castro,   and   J.A.   Glennon.   Effect   of   long-­‐term   propranolol   administraUon   on   parathyroid   hormone  and  calcium  concentraUon  in  primary  hyperparathyroidism.  Ann.  Int.  Med.  91:740,1979.   14. Caro,   J.F.,   N.G.   Sloane,   and   J.A.   Glennon.   Hyperthyroidism   with   normal   serum   T4,   T3   and   TBG   immunoreacUvity.  J.  Clin.  Pat.  33:868,1980.   15. Caro,  J.F.,  and  P.D.  Woolf.  Pituitary-­‐ovarian  axis  responsiUvity  to  prolonged  GnRH  infusion  in  normal  and   hyperprolacUnemic  women.  J.  Clin.  Endo.  Metab.  50:999,1980.   16. Insogna,   K.L.,   D.R.   Bordley,   J.F.   Caro,   and   D.H.   Lockwood.   Osteomalacia   and   weakness   due   to   excessive   antacid  ingesUon.  J.A.M.A.  244:2544,1980.   17. Castro,  J.H.,  J.F.  Caro,  Kim,  and  J.A.  Glennon.  Effects  of  PTH  infusion  in  primary  hyperparathyroidism  on   plasma  prolacUn  in  man.  J.  Clin.  Endo.  Metab.  51:397,1980.   18. Caro,  J.F.,  and  J.M.  Amatruda.  FuncUonal  relaUonship  between  insulin  binding,  acUon  and  degradaUon.  J.   Biol.  Chem.  255:10052,1980.   19. Caro,   J.F.,   and   J.M.   Amatruda.   Insulin   receptors   in   hepatocytes:   Post   receptor   events   mediate   down   regulaUon.  Science  210:1029,1980.   20. Caro,  J.F.,  and  J.M.  Amatruda.    The  effects  of  fasUng  on  glucagon  binding  and  acUon  in  isolated  hepatocytes.   Metabolism  29:732,1980.   21. Caro,  J.F.  and  J.A.  Glennon,  and  H.L.  Israel.      Neuroendocrine  studies  in  sarcoidosis.    William,  J.W.  and  Davis,   B.  H.  (Eds.),  Alpha  Omega  Publ.  pp.587,1980.   22. Cech,  J.N.,  R.B.  Freeman,  J.F.  Caro,  and  J.M.  Amatruda.  Insulin  acUon  and  binding  in  isolated  hepatocytes   from  fasted,  streptozotocin  diabeUc  and  older,  spontaneously  obese  rats.  Biochem.  J.  188:839,1980.   23. Caro,  J.F.,  and  J.M.  Amatruda.  Evidence  for  the  modulaUon  of  insulin  acUon  and  degradaUon  independently   of  insulin  binding.  Am.  J.  Physiol.  240:E325,1981.   24. Besarab,  A.,  J.F.  Caro,  B.U.  Ihle,  J.F.  Burke,  and  J.A.  Glennon.  Suppression  of  secondary  hyperparathyroidism   by  propranolol  in  renal  failure  paUent.  Nephron  27:127,1981.     25. Besarab,  A.  and    J.F.  Caro.    Increased  absolute  calcium  binding  to  albumin  in  hypoalbuminaemia.    J.  Clin.   Path.  34:1368,1981.   26. Basal,  S.,  P.D.  Woolf,  J.A.  Fischer,  and  J.F.  Caro.  Dopamine  does  not  affect  parathyroid  funcUon  in  man.  J.   Clin.  Endo  Metab.  54:651,1982.   27. Caro,  J.F.,  and  J.M.  Amatruda.  The  regulaUon  of  lipid  synthesis  in  freshly  isolated  hepatocytes  and  primary   cultures  of  hepatocytes  from  fasted  rats:  The  primary  role  of  insulin.  Metabolism  31:14,1982.   28. Caro,  J.F.,  and  J.M.  Amatruda.  GlucocorUcoid-­‐induced  insulin  resistance:  The  importance  of  post  receptor   events  in  the  regulaUon  of  insulin  binding  and  degradaUon.  J.  Clin.  Invest.  69:866,1982.     29. Caro,  J.F.,  G.  Muller  and  J.A.  Glennon.  Insulin  processing  by  the  liver.  J.  Biol.  Chem.  257:8459,1982.   30. Kauffman,  J.M.,  and  J.F.  Caro.  Insulin  resistance  in  uremia:  CharacterizaUon  of  insulin  acUon  binding  and   processing  in  isolated  hepatocytes  from  chronic  uremic  rat.  J.  Clin.  Invest.  71:698,1983.