5. Septic (infectious) arthritis
Infection of joint resulted of invasion of the synovial
membrane by microorganisms which can be:
Spread of infection from other parts of the body (hematogenous spread) or
Direct entrance through trauma or surgical instrumentation.
S. aureus causes 50% of all joint infections and 80%
of septic arthritis in patients with rheumatoid arthritis
and diabetes
19. Pathophysiology septic arthritis
Bacterial invasion of synovial space
Inflammation of the synovial tissue
Accumulation of pus in the synovial membrane and
synovial fluid
Abscess accumulation in the synovium and subchondral
bone
Destroying of the cartilage and ankylosis of joints.