Prevalence of Bronchial Asthma Among Patients with Periodontitis

1. Prevalence of Bronchial Asthma
Among Patients with
Periodontitis
Prepared & presented by
ID:
Under Supervision :

2. Objectives
1. Definition of Bronchial Asthma
2. Characteristics of bronchial Asthma
3. Treatment of Bronchial Asthma
4. Relation of bronchial asthma and periodontitis

3. Introduction
• Asthma is a serious global health problem.
• People of all ages in countries throughout the world are affected
by this chronic airway disorder, which can be severe and some-
times fatal.
• The prevalence of asthma is increasing everywhere,
• Several oral health conditions are documented among
asthmatic patients, such as an increased prevalence of
periodontal diseases.1

4. Definition of Bronchial Asthma
• Bronchial asthma is a chronic
respiratory disease that affects 1-20%
of the population of various countries.
• The number of asthma patients in the
world reaches 300 millions and is
estimated to increase by 100 million in
2025.2
• Bronchial asthma is defined as a
disease with chronic inflammation of
the airways that involves many
inflammatory cells and results in
bronchial hyper responsiveness
towards various stimuli and signed by
airway obstruction that is reversible
with or without treatment.3

5. Characteristics of bronchial Asthma
• Asthma is characterized by
episodic or persistent symptom
of
1. Wheezing; a high-pitched
whistling sound made while
breathing
2. Dyspnea; Difficult, painful
breathing or shortness of
breath.
3. Cough (especially at night).

6. Treatment of Bronchial Asthma
• Asthma treatment uses the
following drugs:
1. Bronchodilator/reliever drugs
to dilate the airways.
2. Anti-inflammatory/ controller
drugs to treat inflammation
and control asthma.
• Both bronchodilator and
controller drugs can be
administered by inhalation, oral,
and parenteral.

7. Effective route of drug administration
• The administration of the drug by inhalation is considered more
efficient because it works faster on the target organ and has
minimal systemic effects.
• Short-acting β2 agonists are the type of bronchodilator drugs
that are most commonly used, and inhaled corticosteroids,
which are combined with long-acting β2 agonists.

8. Relation of bronchial asthma and periodontitis
• The long-term use of β2-agonists and inhaled corticosteroids
affect the periodontal tissue by:
1. The content of inhalation drugs can reduce the secretion of
saliva which is exacerbated by the activation of inflammatory
mediators in the gingiva.

9. Relation of bronchial asthma and periodontitis
2. Prolonged use of inhalation drugs results in a decrease of the
defense mechanism of the periodontal tissue which causes
periodontal tissue destruction, and worsen by the patient's
inadequate oral hygiene.

10. Effect of delayed treatment of gingival disease
in bronchial asthma patients
• Periodontal tissue destruction that is not immediately treated
can lead to the progression of periodontal disease to a more
advanced or severe stage(periodontitis).

11. References
1. Arbes SJ Jr., Matsui EC. Can oral pathogens influence allergic disease? J Allergy Clin Immunol
2011;127:1119-27.
2. Gomes-Filho IS, Soledade-Marques KR, Seixas da Cruz S, de Santana Passos-Soares J,
Trindade SC, Barreto ML, et al. Does periodontal infection have an effect on severe asthma in
adults? J Periodontol. 2014;85:e179–187.
3. Ichinose M, Sugiura H, Nagase H, Yamaguchi M, Inoue H, Sagara H, et al. Japanese guidelines
for adult asthma 2017. Allergol Int. 2017; 66(2):163–89.

12. Thank you
Any Questions?