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Apps in the clinical domain
1. Apps in the clinical domain:
what doesn’t work, what
might and why
James Tattersall
Leeds teaching hospitals NHS trust, Mediqal
Health Informatics Limited
jamestattersall@nhs.net
2. Clinical work
• Healthcare is mostly information
management.
• Physicians do nothing else apart from
information management.
3. Medical information
• Safety critical.
• Complex.
• Viewed from different perspectives
– Clinical Specialists
– Clinical Generalists
– Administrators
– Patients
– Carers
5. • “Trusts want systems that are
tailored to their particular
organisation, not standardised
systems.”
– Implementation and adoption of
nationwide electronic health records in
secondary care in England: qualitative
analysis of interim results from a
prospective national evaluation.
Robertson et. al. BMJ 2010;341:c4564
19. Table 1; A simple clinical database designed using the traditional relational model.
Object tables
Drug
Patients ingredient
Staff
patientID Drugs staff ID
Surname drugID s staff name
drug name ingredientID
Firstname staff type
cost ingredient
date of birth date appointed
units of name
Address
Hospital number doseID
Lookup tables Procedure Dose
types frequencie
Units of dose proceduretypeI
Route of s
units of doseID D frequencyID
units of dose administration procedure frequency
name routeID
name name
route
procedure code times per
day
Drug
Event prescriptions
Drug Prescription
tables Procedures Clinics
Blood pressures Admissions ID
procedureID clinicID patientID
Blood pressure ID admission ID
patientID patientID date started
patientID patientID
date date date stopped
date date admitted
procedure typeID clinic typeID drugID
systolic date discharged
procedure note clinic note dose
diastolic reason for admission
staffID performing staffID entered units of doseID
staffID entered discharge summary
staffID entered frequencyID
staffID entered
routeID
staffID entered
staffID stopped
date entered
20. Metadata Fact tables
tables
classID ObjectID
name ClassID
parent_classID Patient name
Is a type of
Smith, John
person
groupID
name
classID Blood
pressure EventID
Describes a ObjectID
patient date
Systolic 01/07/2007
groupID attribute
attributeID belongs to
blood
pressure
group
eventID
attributeID Systolic
attributeID eventID
numeric
name attributeID
value 126
datatype Systolic date value
Units Numeric
mmHg valueID
Maximum
300 text value
Value table valueID
name object value
22. Principle
• The components of the Reference Model
are like LEGO brick specifications
• Archetypes = instructions/designs
constraining the use of LEGO pieces to
create meaningful structures
Information model
Instances
Archetype A Archetype B
25. Blood pressure
management
• Measurement
• Automatic capture
• Posture
• Setting (clinic, admission, home)
• Cause
• Genetics
• Family history
• Associated medical conditions
• Blood tests, screening.
• Allergies
• Co-morbidities
• Drug history
• Prescription
• Risk, cost, benefit.
26. Human genome
• 23 chromosomes
• 25,000 genes.
• 3.2 billion base pairs
• 800 megabytes of data.
• Since individual genomes vary by
less than 1% from each other, the
variations of a given human's
genome from a common reference
can be losslessly compressed to
roughly 4 megabytes.