This document summarizes two neuroimaging case studies presented at a data visualization conference. The first case study discusses a reproducible figure from a 2017 paper that used real-time motion analytics during brain MRI to improve data quality and reduce costs. The second case study describes a "Franken-figure" from a 2012 paper that examined how changes in spontaneous activity measured by accelerometry correlated with the extent of cerebral ischemia-reperfusion injury in primates. Figures from both case studies are included to demonstrate data visualization techniques.
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Neuroimaging Data Viz Case Study
1. NEUROIMAGING
DATA VIZ
CASE STUDY
B I O D A T A C L U B , 4 / 6 / 2 0 1 8
B Y E R I C E A R L
O H S U B E H A V I O R A L N E U R O S C I E N C E D C A N L A B S
2. TELLING STORIES
“There are many true statements about complex
topics that are too long to fit on a PowerPoint slide.”
~ Edward Tufte
“An American statistician and professor
emeritus of political science, statistics, and computer
science at Yale University. He is noted for his writings
on information design and as a pioneer in the field
of data visualization.”
~ Wikipedia, 4/3/18
3. TODAY’S STORIES
The Reproducible Figure
Dosenbach, et al, 2017, Real-time motion analytics during brain MRI improve data quality
quality and reduce costs, NeuroImage.
http://www.sciencedirect.com/science/article/pii/S1053811917306729
The Franken-Figure
Urbanski, et al, 2012, Changes in spontaneous activity assessed by accelerometry correlate
correlate with extent of cerebral ischemia-reperfusion injury in the nonhuman primate,
Translational Stroke Research.
https://link.springer.com/article/10.1007/s12975-012-0191-8
The reproducible figure is from a paper on giving the MRI operator feedback on patient motion between WUSTL and OHSU
The franken-figure is from a paper on a non-human primate stroke model from the ONPRC
What story is this trying to tell? (A trend in 4 scatter plots and 2 scatter plots)
[advance] How about now? (The colors represent groups)
[advance] How about now? (“Mean FD vs Age” in the same cohort split differently)
What do you notice about the points on the a and b plots? (The same points, but different colors)
[advance] And here’s the whole story.
A reproducible figure is good when you may have to refine the figure many times.
What story is this trying to tell? (A trend in 4 scatter plots and 2 scatter plots)
[advance] How about now? (The colors represent groups)
[advance] How about now? (“Mean FD vs Age” in the same cohort split differently)
What do you notice about the points on the a and b plots? (The same points, but different colors)
[advance] And here’s the whole story.
A reproducible figure is good when you may have to refine the figure many times.
What story is this trying to tell? (A trend in 4 scatter plots and 2 scatter plots)
[advance] How about now? (The colors represent groups)
[advance] How about now? (“Mean FD vs Age” in the same cohort split differently)
What do you notice about the points on the a and b plots? (The same points, but different colors)
[advance] And here’s the whole story.
A reproducible figure is good when you may have to refine the figure many times.
What story is this trying to tell? (A trend in 4 scatter plots and 2 scatter plots)
[advance] How about now? (The colors represent groups)
[advance] How about now? (“Mean FD vs Age” in the same cohort split differently)
What do you notice about the points on the a and b plots? (The same points, but different colors)
[advance] And here’s the whole story.
A reproducible figure is good when you may have to refine the figure many times.
“The Franken-figure: A Frankenstein’s Monster of different plots or images used to tell a more cohesive story.”
Any guesses as to the story here?
On the left are axial slices of a rhesus macaque’s brain
On the right are 3D models of those same brains
The top and bottom are 2 days after stroke and 7 days after stroke for that same macaque, respectively
How many pieces of software do you think I used to make this figure?
[advance] And here’s the whole story.
A franken-figure is good to tell a story outside the bounds of one piece of software.
“The Franken-figure: A Frankenstein’s Monster of different plots or images used to tell a more cohesive story.”
Any guesses as to the story here?
On the left are axial slices of a rhesus macaque’s brain
On the right are 3D models of those same brains
The top and bottom are 2 days after stroke and 7 days after stroke for that same macaque, respectively
How many pieces of software do you think I used to make this figure?
[advance] And here’s the whole story.
A franken-figure is good to tell a story outside the bounds of one piece of software.