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Peritoneal Dialysis
The Basics
Copy Right BCIT Specialty Nursing Nephrology
Review
 Review is an overview…students must still review all
course materials from NSNN 7400 to this point to
prepare for the exam…including article materials.
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Definition
 Treatment for renal failure
 Uses clients peritoneal membrane as semipermeable
membrane
 Dialysis fluid instilled into peritoneal cavity
 Continuous modality
 Uremic toxins and solutes move across membrane by
process of Diffusion
 Fluid removal by Osmosis
 Regulates toxins, excess electrolytes and fluids
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What’s the Difference?
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Who Benefits from PD?
 Viable and effective dialysis treatment option for most ESRD clients
 Preserves residual renal function
 Reduces cardiovascular instability
 Decreases potential for systemic inflammation
 Improves blood pressure and volume control
 Allows client independence( travel) , promotes self-management and
self regulation
 Delay in use of blood access sites (AVF/CVC)
 Reduction in health care costs due do home and self management
focus
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Contraindications for PD
 History of multiple abdominal surgeries( scarring and adhesions
may reduce surface area of peritoneal membrane)
 Presence of known peritoneal fissures( openings in between the
peritoneum and the pleura)
 Chronic and severe back pain
 Morbid obesity
 Acute or active diverticular disease ( may lead to ruptures into
peritoneum/ peritonitis.
 Advanced COPD ( increased pressure on diaphragm)
 Incapacitation- self-care not possible/ no caregiver.
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The Terms!
 Dialysate: PD solution composed of water; an osmotic agent,
(dextrose); electrolytes such as sodium, chloride, magnesium,
calcium and buffer; lactate or bicarbonate
 Volume: the amount of dialysate used, typically ranging from two –
three litres
 Effluent: spent dialysate containing wastes and excess fluid from
the process of diffusion and osmosis.
 Fill (or infusion): a short period of time during which fresh dialysate
is instilled into the peritoneal cavity. Approximately 10 minutes.
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The Terms!
 Dwell: the time during which dialysate sits in the peritoneal cavity,
permitting the dialysis to occur. This phase may take
approximately four to five hours to complete for clients on CAPD or
about an hour and a half to complete for clients on APD
 Drain: the short period during which dialysate is removed from the
peritoneal cavity. Takes approximately 20 minutes to complete.
 Exchange: the entire process of fill, dwell and drain. Several
exchanges within a 24 –hour period is typical
 Osmosis: movement of water through a semipermeable
membrane from solution of low concentration into a solution with a
higher concentration
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PD Cannula (Catheter)
• Long pliable tube with many perforations to
assist with fluid instillation and drainage
• Catheter inserted at the bedside under
local anesthetic or in the OR under general
anesthetic
• Small incision made near the belly button
and then the tube is tunneled and the tip
placed in the abdomen
• The catheter is sutured initially
• Needs time to heal and tissue growth to
take place into the cuffs
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Nursing Nephrology
PD
Cannula (Catheter)
 Flushes done post insertion
 After healing complete, ongoing flushing
done and training takes place
 Some of the catheter remains outside the
body at all times
 Catheter may be buried under skin if not
starting treatment for some time
 Exit site must be kept clean and covered
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Types of peritoneal Dialysis
 Continuous Ambulatory Peritoneal Dialysis CAPD
 Performed manually through the day by client
 Generally 4-5 exchanges during waking hours
 Dialysate left in the peritoneal cavity overnight
 Requires little equipment, no power source
 Automated Peritoneal Dialysis APD
 Use of mechanical device called cycler
 Automatically controls exchange process
 Usually performed at night while client asleep
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Removal of Fluid
 Ultrafiltration will be achieved through osmosis.
 Osmosis moves water through a semi-permeable membrane from
a solution of low solute concentration to a solution of high solute
concentration.
 A high solute concentration is required on one side of the
peritoneal membrane.
 Concentration of the PD solution, dwell time, membrane
permeability, oncotic pressure in the capillary beds play an
important role.
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Copy Right BCIT Specialty Nursing Nephrology
Length of time exposed to
membrane (dwell time)
Membrane Permeability
Concentration
Gradient (PD solution)
Factors affecting
rate of Osmosis
Ultrafiltration Achieved through Osmosis:
Oncotic
pressure in
capillary
beds
Osmosis
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PD Focused Assessment
 Ideal weight assessment
 Appetite, nutritional status
 N+V, bowel routine/ constipation
 VS
 Exit site assessment
 Frequency and duration of exchanges
 Effluent ( if applicable)
 Adequacy , PET results
 Blood work
 Medications
 Comorbidities, diabetes etc.
 Psycho-social issues
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Pre-dialysis Assessment:
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Vital
signs
Fluid
intake
Edema
Appetite
Bowels
Respiratory
status
Medications
lab work
JVD
Previous data
Weight
Urine
output
1. Ideal Weight
Assessment
PD Complications
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Purpose:
 To understand common complications that occur in PD, and expand
participant’s knowledge base of troubleshooting techniques.
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Overview
 Membrane Assessment
 Draining Issues
 PD Fluid Gone Wrong
 Exit Site Infection
 Peritonitis
 Catheter Leaks
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Physical Complications of PD
 Tunnel Infection
 Constipation
 Abdominal Discomfort
 Catheter Obstruction
 Hemoperitoneum
 Hypervolemia
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Membrane Assessment
What does a healthy membrane look like?
*No scar tissue, large surface area, no hernias or prior surgeries to the area.
As well as minimizing peritonitis. This will achieve optimal PD.
*If you use larger fill volumes based on the body’s surface area, it will ensure
greater contact of the dialysis solution with the membrane which maximizes
diffusion.
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Important Facts
 PD different then HD in that peritoneal membrane is
permeable to plasma proteins which can be lost in
peritoneal fluid
 Clients protein intake may need to be increased
 During acute inflammation –peritonitis, membrane
permeability temporarily increases. Conversely +
overtime scarring from chronic inflammation can
decrease permeability
 IMPORTANT to keep peritonitis to a minimum.
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Exit Site Infection
Draining Issues
What are draining issues ?
 Blood or fibrin clots
 Air lock
 Constipation
 Catheter migration
 Omental wrap
 Kinked or clamped faulty equipment
 Outflow failure:
The drainage volume is substantially less than the inflow volume and there is no evidence of pericatheter leakage. Usually occurs soon after catheter placement. Often preceded by irregular drainage, increased fibrin in
the dialysate or constipation.
 Inflow failure:
Solution will not flow from the dialysate bag into the peritoneal cavity.
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Draining Issues
 What do we do about that?
Irrigate the peritoneal catheter per program policy.
Notify the Nephrologist when a blockage is suspected.
If using a thrombolytic agent, it requires a dwell period in the catheter in direct contact
with the clot to initiate local fibrinolysis.
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BCPRA
BCPRA
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Draining issues
Patient teaching:
 Assess drained effluent with each exchange for color, clarity and volume.
 Awareness of the importance of maintaining a bowel routine.
 Check for line kinks and or closed clamps as a first step if difficulty in
draining is noted.
 Change position and increase ambulation if difficulty in draining is noted.
 Report changes in drained volume or speed of drainage when noted.
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Draining issues
Documentation:
 Assessed drainage problems
 Appearance and volume of drained effluent
 Treatment options provided
 Patient response to treatment options
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PD fluid gone wrong
 Is this good or bad?
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 What is the situation?
 White strands in effluent are fibrin.
 Fibrin formation increases in peritonitis.
 If untreated the fibrin can block the catheter and cause drain/filling problems.
 What do we do to fix Fibrin?
 Add heparin to solution for a dwell (PD clinic will give dosing).
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PD fluid gone wrong
 Is this good or bad?
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 Causes
 Menstruating women, heavy lifting/trauma to abdomen
 Ruptured cyst if you have polycystic disease
 Recent enema, sigmoidoscopy, colonoscopy
 Recent PD catheter insertion
 It can also be an indication of abdominal trauma, disease and peritonitis.
 What do we do to fix it?
 Do two exchanges- by filling and immediately draining with no dwell time in between. Add heparin to each solution fill bag. Pt should call PD clinic if not clearing in one
day.
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Exit Site infection
 What does it look like:
Red, swollen, painful, tender, draining
 Exit site infection can cause exit site tunnel infection and peritonitis. As a
complication of infection, a patient can have intestinal perforation. Early
surgical intervention and possible catheter removal should be performed
in addition to immediate initiation of therapy with antibiotics or antifungal.
 An exit-site infection that does not respond to treatment may lead to
persistent peritonitis which may require catheter removal or occasional
discontinuation of the peritoneal dialysis.
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Would you remove crusts or scabs at the exit
site?
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 It’s a barrier to exit site entrance. Removal may open it and
allow bacteria inside. It will come off on its own. Patience….
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Peritonitis
 What is it?
Infections can thicken/ scar membrane overtime, PD may not be an option.
 Signs and Symptoms of peritonitis include:
 Abdominal pain
 Cloudy dialysis fluid
 An unusual odour of dialysis fluid
 Bloating or a feeling of fullness in abdomen
 Fever
 Nausea /Vomiting/Diarrhea
 Loss of appetite/ Fatigue
 Inability to pass stool or gas
 Area around PD catheter red or painful
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Sign and symptoms of Peritonitis
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Peritonitis
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Peritonitis
 What do we do about it?
 Instruct patient to Drain PD fluid and keep bag to take to the hospital. Go to ER if PD unit is
closed.
 Peritonitis is one of the most feared complications of PD. As peritonitis is a life threatening
condition, it can be very disturbing for a person. Clients can live in constant fear of having it
– and can be paranoid with personal hygiene. They can isolate themselves from friends
and the outside world to minimize the risk of infection.
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Catheter leaks
S&S:
•Genital, scrotal, or penile edema
•Volume overload with decreased UF
•External fluid at wound or exit site
•Edema of abdomen / increased girth
•Weight gain
•Decreased exchange of drain volume
Abdominal CT scan or fluoroscopy with contrast can reveal catheter leaks. When the catheter is
leaking, PD can be delayed for 2-3 weeks. Sometimes, a client has to be moved for hemodialysis
for 1-2 weeks. Catheter leaks may require surgical repair or catheter replacement. Catheter leakage
can increase the risk for exit site infection and peritonitis. The client may need to visit the PD clinic
more frequently. Body image can also be impacted by this problem.
Copy Right BCIT Specialty Nursing Nephrology
References
• Counts, S.C. Core Curriculum for Nephrology Nursing 5th
edition 2008; 828 - 829.
• Ash S. Peritoneal Access Devices. Handbook of Dialysis,
4th Edition (2007) Lippincott Williams & Wilkins 356- 375
• Piarano, B., Bailie, G., Bernardini, J. et al. ISPD Guidelines
Recommendations. Peritoneal dialysis – related infections
recommendations: 2005 update. Peritoneal Dialysis
International 2005:25:107-31.
• NSNN 7400 NSNN 7400 MODULE 4 COURSE NOTES
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Valuable Resource
 http://www.bcrenalagency.ca/health-
professionals/clinical-resources/pd-patient-training-
modules
 E-Learning Modules
Copy Right BCIT Specialty Nursing Nephrology

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Peritoneal-Dialysis-exam-review.pptx

  • 1. Peritoneal Dialysis The Basics Copy Right BCIT Specialty Nursing Nephrology
  • 2. Review  Review is an overview…students must still review all course materials from NSNN 7400 to this point to prepare for the exam…including article materials. Copy Right BCIT Specialty Nursing Nephrology
  • 3. Definition  Treatment for renal failure  Uses clients peritoneal membrane as semipermeable membrane  Dialysis fluid instilled into peritoneal cavity  Continuous modality  Uremic toxins and solutes move across membrane by process of Diffusion  Fluid removal by Osmosis  Regulates toxins, excess electrolytes and fluids Copy Right BCIT Specialty Nursing Nephrology
  • 4. What’s the Difference? Copy Right BCIT Specialty Nursing Nephrology
  • 5. Copy Right BCIT Specialty Nursing Nephrology
  • 6. Who Benefits from PD?  Viable and effective dialysis treatment option for most ESRD clients  Preserves residual renal function  Reduces cardiovascular instability  Decreases potential for systemic inflammation  Improves blood pressure and volume control  Allows client independence( travel) , promotes self-management and self regulation  Delay in use of blood access sites (AVF/CVC)  Reduction in health care costs due do home and self management focus Copy Right BCIT Specialty Nursing Nephrology
  • 7. Contraindications for PD  History of multiple abdominal surgeries( scarring and adhesions may reduce surface area of peritoneal membrane)  Presence of known peritoneal fissures( openings in between the peritoneum and the pleura)  Chronic and severe back pain  Morbid obesity  Acute or active diverticular disease ( may lead to ruptures into peritoneum/ peritonitis.  Advanced COPD ( increased pressure on diaphragm)  Incapacitation- self-care not possible/ no caregiver. Copy Right BCIT Specialty Nursing Nephrology
  • 8. The Terms!  Dialysate: PD solution composed of water; an osmotic agent, (dextrose); electrolytes such as sodium, chloride, magnesium, calcium and buffer; lactate or bicarbonate  Volume: the amount of dialysate used, typically ranging from two – three litres  Effluent: spent dialysate containing wastes and excess fluid from the process of diffusion and osmosis.  Fill (or infusion): a short period of time during which fresh dialysate is instilled into the peritoneal cavity. Approximately 10 minutes. Copy Right BCIT Specialty Nursing Nephrology
  • 9. The Terms!  Dwell: the time during which dialysate sits in the peritoneal cavity, permitting the dialysis to occur. This phase may take approximately four to five hours to complete for clients on CAPD or about an hour and a half to complete for clients on APD  Drain: the short period during which dialysate is removed from the peritoneal cavity. Takes approximately 20 minutes to complete.  Exchange: the entire process of fill, dwell and drain. Several exchanges within a 24 –hour period is typical  Osmosis: movement of water through a semipermeable membrane from solution of low concentration into a solution with a higher concentration Copy Right BCIT Specialty Nursing Nephrology
  • 10. PD Cannula (Catheter) • Long pliable tube with many perforations to assist with fluid instillation and drainage • Catheter inserted at the bedside under local anesthetic or in the OR under general anesthetic • Small incision made near the belly button and then the tube is tunneled and the tip placed in the abdomen • The catheter is sutured initially • Needs time to heal and tissue growth to take place into the cuffs Copy Right BCIT Specialty Nursing Nephrology
  • 11. PD Cannula (Catheter)  Flushes done post insertion  After healing complete, ongoing flushing done and training takes place  Some of the catheter remains outside the body at all times  Catheter may be buried under skin if not starting treatment for some time  Exit site must be kept clean and covered Copy Right BCIT Specialty Nursing Nephrology
  • 12. Types of peritoneal Dialysis  Continuous Ambulatory Peritoneal Dialysis CAPD  Performed manually through the day by client  Generally 4-5 exchanges during waking hours  Dialysate left in the peritoneal cavity overnight  Requires little equipment, no power source  Automated Peritoneal Dialysis APD  Use of mechanical device called cycler  Automatically controls exchange process  Usually performed at night while client asleep Copy Right BCIT Specialty Nursing Nephrology
  • 13. Removal of Fluid  Ultrafiltration will be achieved through osmosis.  Osmosis moves water through a semi-permeable membrane from a solution of low solute concentration to a solution of high solute concentration.  A high solute concentration is required on one side of the peritoneal membrane.  Concentration of the PD solution, dwell time, membrane permeability, oncotic pressure in the capillary beds play an important role. Copy Right BCIT Specialty Nursing Nephrology
  • 14. Copy Right BCIT Specialty Nursing Nephrology Length of time exposed to membrane (dwell time) Membrane Permeability Concentration Gradient (PD solution) Factors affecting rate of Osmosis Ultrafiltration Achieved through Osmosis: Oncotic pressure in capillary beds
  • 15. Osmosis Copy Right BCIT Specialty Nursing Nephrology
  • 16. PD Focused Assessment  Ideal weight assessment  Appetite, nutritional status  N+V, bowel routine/ constipation  VS  Exit site assessment  Frequency and duration of exchanges  Effluent ( if applicable)  Adequacy , PET results  Blood work  Medications  Comorbidities, diabetes etc.  Psycho-social issues Copy Right BCIT Specialty Nursing Nephrology
  • 17. Pre-dialysis Assessment: Copy Right BCIT Specialty Nursing Nephrology Vital signs Fluid intake Edema Appetite Bowels Respiratory status Medications lab work JVD Previous data Weight Urine output 1. Ideal Weight Assessment
  • 18. PD Complications Copy Right BCIT Specialty Nursing Nephrology
  • 19. Purpose:  To understand common complications that occur in PD, and expand participant’s knowledge base of troubleshooting techniques. Copy Right BCIT Specialty Nursing Nephrology
  • 20. Overview  Membrane Assessment  Draining Issues  PD Fluid Gone Wrong  Exit Site Infection  Peritonitis  Catheter Leaks Copy Right BCIT Specialty Nursing Nephrology
  • 21. Physical Complications of PD  Tunnel Infection  Constipation  Abdominal Discomfort  Catheter Obstruction  Hemoperitoneum  Hypervolemia Copy Right BCIT Specialty Nursing Nephrology
  • 22. Membrane Assessment What does a healthy membrane look like? *No scar tissue, large surface area, no hernias or prior surgeries to the area. As well as minimizing peritonitis. This will achieve optimal PD. *If you use larger fill volumes based on the body’s surface area, it will ensure greater contact of the dialysis solution with the membrane which maximizes diffusion. Copy Right BCIT Specialty Nursing Nephrology
  • 23. Important Facts  PD different then HD in that peritoneal membrane is permeable to plasma proteins which can be lost in peritoneal fluid  Clients protein intake may need to be increased  During acute inflammation –peritonitis, membrane permeability temporarily increases. Conversely + overtime scarring from chronic inflammation can decrease permeability  IMPORTANT to keep peritonitis to a minimum. Copy Right BCIT Specialty Nursing Nephrology
  • 24. Copy Right BCIT Specialty Nursing Nephrology Exit Site Infection
  • 25. Draining Issues What are draining issues ?  Blood or fibrin clots  Air lock  Constipation  Catheter migration  Omental wrap  Kinked or clamped faulty equipment  Outflow failure: The drainage volume is substantially less than the inflow volume and there is no evidence of pericatheter leakage. Usually occurs soon after catheter placement. Often preceded by irregular drainage, increased fibrin in the dialysate or constipation.  Inflow failure: Solution will not flow from the dialysate bag into the peritoneal cavity. Copy Right BCIT Specialty Nursing Nephrology
  • 26. Draining Issues  What do we do about that? Irrigate the peritoneal catheter per program policy. Notify the Nephrologist when a blockage is suspected. If using a thrombolytic agent, it requires a dwell period in the catheter in direct contact with the clot to initiate local fibrinolysis. Copy Right BCIT Specialty Nursing Nephrology
  • 27. BCPRA BCPRA Copy Right BCIT Specialty Nursing Nephrology
  • 28. Draining issues Patient teaching:  Assess drained effluent with each exchange for color, clarity and volume.  Awareness of the importance of maintaining a bowel routine.  Check for line kinks and or closed clamps as a first step if difficulty in draining is noted.  Change position and increase ambulation if difficulty in draining is noted.  Report changes in drained volume or speed of drainage when noted. Copy Right BCIT Specialty Nursing Nephrology
  • 29. Draining issues Documentation:  Assessed drainage problems  Appearance and volume of drained effluent  Treatment options provided  Patient response to treatment options Copy Right BCIT Specialty Nursing Nephrology
  • 30. PD fluid gone wrong  Is this good or bad? Copy Right BCIT Specialty Nursing Nephrology
  • 31.  What is the situation?  White strands in effluent are fibrin.  Fibrin formation increases in peritonitis.  If untreated the fibrin can block the catheter and cause drain/filling problems.  What do we do to fix Fibrin?  Add heparin to solution for a dwell (PD clinic will give dosing). Copy Right BCIT Specialty Nursing Nephrology
  • 32. PD fluid gone wrong  Is this good or bad? Copy Right BCIT Specialty Nursing Nephrology
  • 33.  Causes  Menstruating women, heavy lifting/trauma to abdomen  Ruptured cyst if you have polycystic disease  Recent enema, sigmoidoscopy, colonoscopy  Recent PD catheter insertion  It can also be an indication of abdominal trauma, disease and peritonitis.  What do we do to fix it?  Do two exchanges- by filling and immediately draining with no dwell time in between. Add heparin to each solution fill bag. Pt should call PD clinic if not clearing in one day. Copy Right BCIT Specialty Nursing Nephrology
  • 34. Copy Right BCIT Specialty Nursing Nephrology
  • 35. Exit Site infection  What does it look like: Red, swollen, painful, tender, draining  Exit site infection can cause exit site tunnel infection and peritonitis. As a complication of infection, a patient can have intestinal perforation. Early surgical intervention and possible catheter removal should be performed in addition to immediate initiation of therapy with antibiotics or antifungal.  An exit-site infection that does not respond to treatment may lead to persistent peritonitis which may require catheter removal or occasional discontinuation of the peritoneal dialysis. Copy Right BCIT Specialty Nursing Nephrology
  • 36. Would you remove crusts or scabs at the exit site? Copy Right BCIT Specialty Nursing Nephrology
  • 37.  It’s a barrier to exit site entrance. Removal may open it and allow bacteria inside. It will come off on its own. Patience…. Copy Right BCIT Specialty Nursing Nephrology
  • 38. Peritonitis  What is it? Infections can thicken/ scar membrane overtime, PD may not be an option.  Signs and Symptoms of peritonitis include:  Abdominal pain  Cloudy dialysis fluid  An unusual odour of dialysis fluid  Bloating or a feeling of fullness in abdomen  Fever  Nausea /Vomiting/Diarrhea  Loss of appetite/ Fatigue  Inability to pass stool or gas  Area around PD catheter red or painful Copy Right BCIT Specialty Nursing Nephrology
  • 39. Sign and symptoms of Peritonitis Copy Right BCIT Specialty Nursing Nephrology
  • 40. Peritonitis Copy Right BCIT Specialty Nursing Nephrology
  • 41. Peritonitis  What do we do about it?  Instruct patient to Drain PD fluid and keep bag to take to the hospital. Go to ER if PD unit is closed.  Peritonitis is one of the most feared complications of PD. As peritonitis is a life threatening condition, it can be very disturbing for a person. Clients can live in constant fear of having it – and can be paranoid with personal hygiene. They can isolate themselves from friends and the outside world to minimize the risk of infection. Copy Right BCIT Specialty Nursing Nephrology
  • 42. Catheter leaks S&S: •Genital, scrotal, or penile edema •Volume overload with decreased UF •External fluid at wound or exit site •Edema of abdomen / increased girth •Weight gain •Decreased exchange of drain volume Abdominal CT scan or fluoroscopy with contrast can reveal catheter leaks. When the catheter is leaking, PD can be delayed for 2-3 weeks. Sometimes, a client has to be moved for hemodialysis for 1-2 weeks. Catheter leaks may require surgical repair or catheter replacement. Catheter leakage can increase the risk for exit site infection and peritonitis. The client may need to visit the PD clinic more frequently. Body image can also be impacted by this problem. Copy Right BCIT Specialty Nursing Nephrology
  • 43. References • Counts, S.C. Core Curriculum for Nephrology Nursing 5th edition 2008; 828 - 829. • Ash S. Peritoneal Access Devices. Handbook of Dialysis, 4th Edition (2007) Lippincott Williams & Wilkins 356- 375 • Piarano, B., Bailie, G., Bernardini, J. et al. ISPD Guidelines Recommendations. Peritoneal dialysis – related infections recommendations: 2005 update. Peritoneal Dialysis International 2005:25:107-31. • NSNN 7400 NSNN 7400 MODULE 4 COURSE NOTES Copy Right BCIT Specialty Nursing Nephrology