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1. Chikungunya Virus
-Mohammed Huzaifa Saud

2. Introduction
 Chikunguniya fever is a re-emerging disease
characterized by acute fever with severe
arthralgia.
 Name is derive from south african language
which means "that which bends up or gets
folded.“
 This virus was first isolated from human
patients in Tanzania in 1952.

3. Chikungunya a mosquito transmitted Viral
infection.
Family: Togaviridae Genus: Alpha Virus(RNA)
Vector:Aedes Aegypti

4. Transmission of Infection
Transmission of virus is maintained by 2 cycles:
1.Sylvatic cycle
2.Human cycle
Sylvatic Cycle Human Cycle

5. Clinical Manifestation
 Incubation Peroid is of 3-5 days.
 Most common symptoms are fever and severe joint pain ( due arthritis).
 Arthritis is polyarticular, migratory and edematous (joint swelling),
affecting the small joints of wrists and ankles.
 Other symptoms include headache, muscle pain, skin rashes.
 Most patients recover within a week, except for the joint pain (lasts for
months).
Headache Arthritis Fever Skin Rashes

6. Laboratory Diagnosis
Detection of IgM or IgG in a paired serum sample by
ELISA is the mainstay of diagnosis.
Reverse transcriptase PCR can be used to detect viral
RNA.

7. Thank You