Niemann Pick Disease is a rare genetic disorder characterized by the inability of the body to transport fatty substances like lipids and cholestrol inside the cells of the body.
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Niemann Pick Disease Type-C
1. Niemann-Pick Disease Type C Market
DelveInsight’s ‘Niemann-Pick Disease Type C (NPC) - Market Insights, Epidemiology and Market
Forecast-2027’ report delivers an in-depth understanding of the disease, historical & forecasted
epidemiology as well as the market trends of Niemann-Pick Disease Type C (NPC) in the United States,
EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.
The Report provides the current treatment practices, emerging drugs having the potential to get
launched in the forecast period, market share of the individual therapies, current and forecasted market
size of Niemann-Pick Disease Type C (NPC) from 2016 to 2027 segmented by seven major markets. The
Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet
medical needs to curate best of the opportunities and assess underlying potential of the market.
Geography Covered
The United States
EU5 (Germany, France, Italy, Spain and the United Kingdom)
Japan
Study Period : 2016-2027
Niemann-Pick Disease Type C (NPC) - Disease Understanding and Treatment Algorithm
The DelveInsight Niemann-Pick Disease Type C (NPC) market report gives the thorough understanding of
the Niemann-Pick Disease Type C (NPC) by including details such as disease definition, classification,
symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and
treatment guidelines for Niemann-Pick Disease Type C (NPC) in the US, Europe, and Japan.
Niemann-Pick Disease Type C (NPC) Epidemiology
The Niemann-Pick Disease Type C (NPC) epidemiology division provide the insights about historical and
current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of
current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part
of the DelveInsight report also provides the diagnosed and treatable patient pool and their trends along
with assumptions undertaken.
The disease epidemiology covered in the report is segmented by total prevalent patient population,
diagnosed population, sub-types specific cases (NPC1 and NPC 2) and clinical distribution of NPC by
phenotypes (early infantile, late infantile, juvenile and adult).
According to DelveInsight, the total prevalent population of NPC was found to be 2,099 in the year 2016
in 7MM.
Niemann-Pick Disease Type C (NPC) Drug Chapters
This segment of the Niemann-Pick Disease Type C (NPC) report encloses the detailed analysis of
marketed drugs and late stage (Phase-III) pipeline drugs. It also helps to understand the clinical trial
details, expressive pharmacological action, agreements and collaborations, approval and patent details,
advantages and disadvantages of each included drug and the latest news and press releases.
The drugs marketed for the treatment mainly includes Substrate Reduction Therapy – Zavesca
[Miglustat; Actelion] and Supportive Therapies for the management of symptoms associated with NPC -
Antiepileptics (Seizures); Tricyclic Antidepressants & CNS Stimulants (Cataplexy); Anticholinergics,
Trihexyphenydil & GABA Derivatives (Dystonia & Tremor); atypical antipsychotics (Psychosis). Detailed
chapters for all of these drugs, along with the upcoming therapies i.e., [VTS-270 (Mallinckrodt),
2. Arimoclomol (Orphazyme), and Trappsol Cyclo (CTD Holdings, Inc.) have been covered in the report.
Niemann-Pick Disease Type C (NPC) Market Outlook
The Niemann-Pick Disease Type C (NPC) market outlook of the report helps to build the detailed
comprehension of the historic, current and forecasted trend of the market by analyzing the impact of
current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
This segment gives a through detail of market trend of each marketed drug and late-stage pipeline
therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria,
mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered
patient segment, expected launch year, competition with other therapies, brand value, their impact on
the market and view of the key opinion leaders. The calculated market data are presented with relevant
tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the global market of Niemann-Pick Disease Type C (NPC) was estimated to be
USD 27.61 billion in 2016.
Niemann-Pick Disease Type C (NPC) Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the market or will
get launched in the market during the study period from 2016-2027. The analysis covers market uptake
by drugs; patient uptake by therapies and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of
new drugs and allows the comparison of the drugs on the basis of market share and size which again will
be useful in investigating factors important in market uptake and in making financial and regulatory
decisions.
The market size of Niemann-Pick Disease Type C (NPC) includes the drug-uptake for individual therapies,
which is further segmented on the basis of market size and market share by Line of therapy and Route
of Administration.
Niemann-Pick Disease Type C (NPC) Report Insights
Patient Population
Therapeutic Approaches
Pipeline Analysis
Market Size and Trends
Market Opportunities
Impact of upcoming Therapies
Niemann-Pick Disease Type C (NPC) Report Key Strengths
10 Year Forecast
7MM Coverage
Epidemiology Segmentation
Drugs Uptake
Highly Analyzed Market
Key Cross Competition
Niemann-Pick Disease Type C (NPC) Report Assessment
3. Current Treatment Practices
Unmet Needs
Detailed Pipeline Product Profiles
Market Attractiveness
Market Drivers and Barriers
Key Benefits
This DelveInsight report will help to develop Business Strategies by
understanding the trends shaping and driving the Niemann-Pick Disease Type C
(NPC) market
Organize sales and marketing efforts by identifying the best opportunities for Niemann-Pick
Disease Type C (NPC) market
To understand the future market competition in the Niemann-Pick Disease Type C (NPC) market