27. RA
huhhdddddd
R R Down
X A stream
R R targets
RARE DNA BINDING SITE
28.
29. KEY
Beta Carotene
STRA6 specific receptor
BCO-I
RALD Retinaldehyde
Cellular Retinol Binding Protein
CRBP
ADH Alcohol Dehydrogenase
LRAT Lecithin Retinol Acytransferase
RALDH Retinaldehyde Dehydrogenase
Retinyl Ester
Cellular Retinoic Acid
Binding Protein
Retinyl Ester Hydrolase
REH Retinoic Acid
RA
Retinol
R Retinoic X Receptor
X
(RBP4) Retinol Binding Protein
R
30. CYP26
R
A Retinoic Acid Receptor
R
Down
Direction to down stream targets
stream
targets
RARE DNA BINDING SITE Retinoic Acid Response Element
31.
32. References
Thodosiou, M. "From Carrot to Clinia: an Overview of the Retinoic Acid Signaling Pathway." MS. Universite De
Lyon, Lyon. Web 2009
Duester, Gregg. "Retinoi Acid Synthesis and Signaling during Early Organogenesis." 2008. MS. Burham Institute
for Medical Research California, La Jolla
Bérubé, Martin. Cartoon-boat-3. Digital image. Http://www.how-to-draw-funny-cartoons.com.
Sell.classyboats.com, 2008. Web. 7 Oct. 2011. http://www.how-to-draw-funny-cartoons.com/cartoon-
boat.html
That's All Folks. Digital image. Http://fringefamily.typepad.com. Web. 6 Oct. 2011.
<http://fringefamily.typepad.com/.a/6a0105364a8fba970c014e885b7218970d-800wi>.
Blood Cells. Digital image. Http://photo-dict.faqs.org/phrase/650/blood-cells.html. 2011. Web. 6 Oct. 2011.
<http://www.google.com/imgres?
33. Liver and intestines. Digital image. Http://www.fotolia.com/. Fotolia, 2004. Web. 6 Oct. 2011
Digestive Sytem. Http://www.infovisual.info/03/057_en.html, 2005.
Polyps in the Colon. Digital image. Http://www.revolutionhealth.com. 2011. Web. 7 Oct. 2011.
<http://www.revolutionhealth.com/articles/colon-cancer-treatment---patient-information-nci-
pdq-/ncicdr0000062954>.
Retinyl Ester. Digital image. Http://www.antioxidantsdetective.com. 2010. Web. 6 Oct. 2011.
<http://www.antioxidantsdetective.com/structure-of-retinyl-ester.html>.
Bugs Bunny. Digital image. Zbrushcentral.com. Web. 7 Oct. 2011
What's up Doc? Dir. Mobydick725. Perf. Bugs Bunny. Http://www.youtube.com. Web. 9 Oct. 2011.
<http://www.youtube.com/watch?v=qO-Np9-pIkY>.
34. Plasma Membrane. Digital image. Http://www.prism.gatech.edu. Web. 9 Oct. 2011
STRA6. Digital image. Http://sd3.myipcn.org. Web. 1 Oct. 2011.
<http://sd3.myipcn.org/science/article/pii/B9780123860415000017>.
