Presentasi tentang pengaruh PPI dengan kejadian penyakit kardiovaskular

1. PPI and CVD
Deri Arara, MD

2. Deri Arara, MD
Mr. C, 70 years old
Anamnesis :
Chest pain since 7 hours before admission. Prior history
of smoker and diabetes. 2 years ago also had history of
blood transfusion due to melena.
Physical examination:
Vas :5 ; Thorax : in normal limit, abdomen: epigastric
pain (+)
EKG : Sinus Rythm, ST depression at V3-V6
Lab: Hb 10.5 gr/dl, leukocyte 7.000, eGFR 40 cc/min

3. Deri Arara, MD
Patient then underwent early PCI and implanted stent at proximal LAD (CAD 1 VD)
Which one is correct management regarding of duration and also gastric protector
for this patient ?
a. Aspirin + Clopidogrel for 12 months + ranitidine as gastric protector
b. Aspirin + Clopidogrel for 12 months + omeprazole as gastric protector
c. Aspirin + Clopidogrel for 12 months without gastric protector
d. Aspirin + Clopidogrel for 6 months + rabeprazole (pariet) as gastric protector
e. Aspirin + Clopidogrel for 6 months + omeprazole as gastric protector

4. 62

5. Antiplatelet and PPI
Saven, et al. Cureus. 2022. 14(2): e 21885
Scott, et al. Expert Opin Drug MetabToxicol. 2014; 10 (2): 175-89

6. Flowchart of the antiplatelet and PPI co-
administration recommendations
Scott, et al. Expert Opin Drug MetabToxicol. 2014; 10 (2): 175-89

7. Deri Arara, MD
Thank You