Analysis of the current and future market dynamics of PAH market across the US, EU5 (Germany, Spain, Italy, France and United Kingdom) and Japan

1. Pulmonary Arterial
Hypertension (PAH)
Market Insights,
Epidemiology and
Market Forecast 2025
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2. Pulmonary Arterial Hypertension
(PAH)
• Pulmonary Arterial Hypertension (PAH), [WHO
Class I] is a rare, chronic, and progressive form of
Pulmonary Hypertension, which is characterized
by the elevated pulmonary arterial pressure
(PAP) and pulmonary vascular resistance (PVR)
in blood vessels carrying the blood from right side
of heart through lungs.
• It occurs due to the tightening and stiffening of
the small pulmonary arteries leading to the right
ventricular dysfunction and vessel obstruction.
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3. Report Highlights
Analysis of the current and future market dynamics of
PAH market across the US, EU5 (Germany, Spain,
Italy, France and United Kingdom) and Japan
Forecasted sales of PAH
Treatment market for
each of the 7 major
markets, as well as RoE
and RoW
Detailed Assessment of
Clinical trials results of
emerging therapies
Detailed epidemiology
analysis for each of the
7 Major markets
Assessments of the PAH
Treatment marketed
brands and late stage
pipeline products.
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4. Market Key Findings
Global Market Size is expected to be
USD 9.9 Billion by 2025
Endothelin receptor antagonists
contribute major share to the PAH
market
Rising demand of Prostanoids
will fuel the growth of the
market
Flourishing market size, despite the
patent loss of key drugs, owing to
the launch of the first ever gene
therapy in the United States
DelveInsight believes that the
emerging Prostanoid therapies shall
show remarkable growth in the coming
years and have the
potential to become the Standard of
Care
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5. Prevalent Population of PAH in 7 Major
Markets
-
5,000
10,000
15,000
20,000
25,000
2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
Idiopathic PAH Drug/Toxin Induced
CTD associated PAH HIV-related PAH
Portopulmonary Hypertension associated PAH CHD associated PAH
Heritable PAH
PopulationNumber(N)
5000
25,000
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6. Market Forecast
The global
market size of
PAH is expected
to grow at a
CAGR of 7.41%
from 2015 to
2025
LetairisVolibris
(GlaxoSmithKlineGilead
Science), Opsumit(Actelion
Pharmaceuticals Ltd) and
Tracleer (Actelion
Pharmaceuticals) are the
most recommended
endothelin receptor
antagonists
According to
DelveInsight forecasts,
the market is expected
to experience a steady
rise after 2019, which is
attributed to the launch
of new drugs
The launch of new drugs
such as Aurora-GT(First
ever gene therapy for PAH;
to be launched in the
United States) and
Tysuberprost (United
Therapeutics Corp.).
The additional approval of
Opsumit (Actelion
Pharmaceuticals Ltd.) for
the treatment of Pediatric
Pulmonary Arterial
Hypertension shall also
fuel the growth of the
market.
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7. Global Market Size of PAH (2015-
2025)
$9,936.71
$-
$2,000.00
$4,000.00
$6,000.00
$8,000.00
$10,000.00
$12,000.00
2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
RevenueinUSD,Million
The global market size of PAH is expected to reach up to USD 9.9 Billion by the year 2025.
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8. Key Companies
Companies with Market
Dominance
Companies with Emerging
Products
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9. Complete Information
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10. About DelveInsight
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11. • Market Size
• Market Dynamics
• Market Assessment
• Trends Analysis
• Physicians & Patients Perception
• KOLs
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